acompound

Showing entry for L-Asparagine

General Compound Information
BXGC Id	BXGC0000458
Compound Name	L-Asparagine
Structure
Formula	C4H8N2O3
InchiKey	DCXYFEDJOCDNAF-REOHCLBHSA-N
SMILES	N[C@@H](CC(N)=O)C(O)=O
Inchi	InChI=1S/C4H8N2O3/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H2,6,7)(H,8,9)/t2-/m0/s1
IUPAC	(2S)-2-amino-3-carbamoylpropanoic acid
Molecular Weight	132.12
Pubchem Id	6267
Chembl Id	CHEMBL58832

Targets of Information Source

DrugBank

DB00174

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Q15758	BXGT013594	Neutral amino acid transporter B(0)	reviewed	Transporter	SLC1A5	approved; investigational; nutraceutical	-
Q7L266	BXGT016993	Isoaspartyl peptidase/L-asparaginase	reviewed	Enzyme	ASRGL1	approved; investigational; nutraceutical	substrate
Q96I59	BXGT019675	Probable asparagine--tRNA ligase, mitochondrial	reviewed	Enzyme	NARS2	approved; investigational; nutraceutical	-
P08243	BXGT006755	Asparagine synthetase [glutamine-hydrolyzing]	reviewed	Enzyme	ASNS	approved; investigational; nutraceutical	-
O43776	BXGT004624	Asparagine--tRNA ligase, cytoplasmic	reviewed	Enzyme	NARS	approved; investigational; nutraceutical	-
Q9H2H9	BXGT022646	Sodium-coupled neutral amino acid transporter 1	reviewed	Transporter	SLC38A1	approved; investigational; nutraceutical	-
Q96QD8	BXGT022647	Sodium-coupled neutral amino acid transporter 2	reviewed	Transporter	SLC38A2	approved; investigational; nutraceutical	-
Q99624	BXGT019942	Sodium-coupled neutral amino acid transporter 3	reviewed	Transporter	SLC38A3	approved; investigational; nutraceutical	-
Q969I6	BXGT022648	Sodium-coupled neutral amino acid transporter 4	reviewed	Transporter	SLC38A4	approved; investigational; nutraceutical	inhibitor

PDB

ASN

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
P00963	BXGT005706	Aspartate--ammonia ligase	reviewed	asnA	-	-	-	-	-
P01575	BXGT005769	Interferon beta	reviewed	Ifnb1	-	-	-	-	-
P03369	BXGT006058	Gag-Pol polyprotein	reviewed	gag-pol	-	-	-	-	-
P39377	BXGT010114	Isoaspartyl dipeptidase	reviewed	iadA	-	-	-	-	-
P0ACI6	BXGT007266	Regulatory protein AsnC	reviewed	asnC	-	-	-	-	-
P63488	BXGT011524	Glutamyl-tRNA(Gln) amidotransferase subunit A	reviewed	gatA	-	-	-	-	-
Q47898	BXGT014720	N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase	reviewed		-	-	-	-	-
P0A962	BXGT007174	L-asparaginase 1	reviewed	ansA	-	-	-	-	-
P94421	BXGT012131	Petrobactin-binding protein YclQ	reviewed	yclQ	-	-	-	-	-
O66610	BXGT004952	Glutamyl-tRNA(Gln) amidotransferase subunit A	reviewed	gatA	-	-	-	-	-
Q5F9C2	BXGT015365	Uncharacterized protein	unreviewed	NGO_0477	-	-	-	-	-
P00784	BXGT005655	Papain	reviewed		-	-	-	-	-
Q9V228	BXGT021859	AsnS-like asparaginyl-tRNA synthetase related protein	unreviewed	asnS-like	-	-	-	-	-
P00876	BXGT005680	Ribulose bisphosphate carboxylase large chain	reviewed	rbcL	-	-	-	-	-
G1EUI6	BXGT003425	Lectin	unreviewed	pelA	-	-	-	-	-
V5IRV7	BXGT022583	Thermolysin	unreviewed		-	-	-	-	-
H0W0T5	BXGT003576	Uncharacterized protein	unreviewed	ASPG	-	-	-	-	-
N1P8Q8	BXGT003874	Nta1p	unreviewed	CENPK1137D_1355	-	-	-	-	-
Q9CES5	BXGT020233	Glutamine ABC transporter permease and substrate binding protein protein	unreviewed	glnP	-	-	-	-	-
P40969	BXGT010213	Centromere DNA-binding protein complex CBF3 subunit B	reviewed	CEP3	-	-	-	-	-
P96257	BXGT012172	Probable glutamine-binding lipoprotein GlnH (GLNBP)	unreviewed	glnH	-	-	-	-	-
Q9KQ43	BXGT024361	Methyl-accepting chemotaxis protein	unreviewed	VC_2161	-	-	-	6300	-
G3JPF7	BXGT024674	Chitinase	unreviewed	CCM_08020	-	-	-	-	-
P00805	BXGT005663	L-asparaginase 2	reviewed	ansB	-	-	-	-	-
Q8A0N4	BXGT025630	Endo-beta-N-acetylglucosaminidase F1	unreviewed	BT_3987	-	-	-	-	-
P14618	BXGT008027	Pyruvate kinase PKM	reviewed	PKM	Kinase	-	-	-	-
Q9BYC5	BXGT025656	Alpha-(1,6)-fucosyltransferase	reviewed	FUT8	-	-	-	-	-

Binding DB

181137

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT006812	Cytochrome P450 3A4	reviewed	Enzyme	CYP3A4	-	>10000	-	-

CHEMBL

CHEMBL58832

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
Q9Z1J7	BXGT022405	Amino acid transporter	unreviewed	-	Slc1a5	IC50	'='	57200	nM
Q91Y77	BXGT019323	Monocarboxylate transporter 10	reviewed	-	Slc16a10	Activity	-	-	-
Q15758	BXGT013594	Neutral amino acid transporter B(0)	reviewed	Transporter	SLC1A5	IC50	'='	674000	nM
P43007	BXGT010350	Neutral amino acid transporter A	reviewed	Transporter	SLC1A4	IC50	'='	656000	nM
P08684	BXGT006812	Cytochrome P450 3A4	reviewed	Enzyme	CYP3A4	IC50	'>'	10000	nM
Q9Z1J7	BXGT022405	Amino acid transporter	unreviewed	-	Slc1a5	IC50	'='	108000	nM
P63116	BXGT011501	Asc-type amino acid transporter 1	reviewed	-	Slc7a10	IC50	'='	668000	nM
Q9Z1J7	BXGT022405	Amino acid transporter	unreviewed	-	Slc1a5	Inhibition	'>='	25	%
Q4CVY4	BXGT026093	Carbonic anhydrase-like protein, putative	unreviewed	-	Tc00.1047053509597.20	KA	'>'	100	uM
P00918	BXGT005690	Carbonic anhydrase 2	reviewed	-	CA2	KA	'>'	100	uM
P00915	BXGT005689	Carbonic anhydrase 1	reviewed	-	CA1	KA	'='	11	uM

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00006	Garden onion	Allium cepa	Vegetables
BXGF00008	Garlic	Allium sativum	Herbs and Spices
BXGF00012	Pineapple	Ananas comosus	Fruits
BXGF00015	Wild celery	Apium graveolens	Herbs and Spices
BXGF00018	Horseradish	Armoracia rusticana	Herbs and Spices
BXGF00019	Tarragon	Artemisia dracunculus	Herbs and Spices
BXGF00021	Asparagus	Asparagus officinalis	Vegetables
BXGF00022	Oat	Avena sativa	Cereals and cereal products
BXGF00027	Chinese mustard	Brassica juncea	Vegetables
BXGF00038	Tea	Camellia sinensis	Teas
BXGF00040	Pepper (C. annuum)	Capsicum annuum	Vegetables
BXGF00056	Mandarin orange (Clementine, Tangerine)	Citrus reticulata	Fruits
BXGF00057	Sweet orange	Citrus sinensis	Fruits
BXGF00059	Arabica coffee	Coffea arabica	Coffee and coffee products
BXGF00065	Cucumber	Cucumis sativus	Gourds
BXGF00088	Barley	Hordeum vulgare	Cereals and cereal products
BXGF00098	Lentils	Lens culinaris	Pulses
BXGF00105	Apple	Malus pumila	Fruits
BXGF00115	Bitter gourd	Momordica charantia	Gourds
BXGF00125	Rice	Oryza sativa	Cereals and cereal products
BXGF00129	Parsnip	Pastinaca sativa	Vegetables
BXGF00134	Common bean	Phaseolus vulgaris	Pulses
BXGF00135	Date	Phoenix dactylifera	Fruits
BXGF00146	Sour cherry	Prunus cerasus	Fruits
BXGF00155	Blackcurrant	Ribes nigrum	Fruits
BXGF00162	Red raspberry	Rubus idaeus	Fruits
BXGF00165	Common sage	Salvia officinalis	Herbs and Spices
BXGF00169	Rye	Secale cereale	Cereals and cereal products
BXGF00173	Garden tomato (var.)	Solanum lycopersicum var. lycopersicum	Vegetables
BXGF00174	Eggplant	Solanum melongena	Vegetables
BXGF00184	Linden	Tilia	Herbs and Spices
BXGF00197	Broad bean	Vicia faba	Pulses
BXGF00199	Gram bean	Vigna mungo	Pulses
BXGF00200	Mung bean	Vigna radiata	Pulses
BXGF00206	Ginger	Zingiber officinale	Herbs and Spices
BXGF00225	Swiss chard	Beta vulgaris ssp. cicla	Vegetables
BXGF00246	Red beetroot	Beta vulgaris var. rubra	Vegetables
BXGF00337	Ginkgo nuts	Ginkgo biloba	Herbs and Spices
BXGF00363	Wild leek	Allium ampeloprasum	Vegetables
BXGF00369	Sacred lotus	Nelumbo nucifera	Vegetables
BXGF00370	White lupine	Lupinus albus	Pulses
BXGF00380	White mustard	Sinapis alba	Herbs and Spices
BXGF00393	Pepper (C. frutescens)	Capsicum annuum var. annuum	Vegetables
BXGF00446	Sugar apple	Annona squamosa	Fruits
BXGF00519	Wheat	Triticum	Cereals and cereal products
BXGF00802	Soft-necked garlic	Allium sativum L. var. sativum	Herbs and Spices
BXGF00819	Pulses		Pulses
BXGF00824	Green vegetables		Vegetables
BXGF00825	Root vegetables		Vegetables
BXGF00828	Yellow zucchini	Cucurbita pepo var. cylindrica	Gourds
BXGF00829	Green bell pepper	Capsicum annuum	Vegetables
BXGF00830	Yellow bell pepper	Capsicum annuum	Vegetables
BXGF00831	Orange bell pepper	Capsicum annuum	Vegetables
BXGF00832	Red bell pepper	Capsicum annuum	Vegetables
BXGF00840	Romaine lettuce	Lactuca sativa L. var. longifolia	Vegetables
BXGF00845	Castanospermum australe	Castanospermum australe	Vegetables
BXGF01140	Angelica gigas	Angelica gigas	Medicinal Plant
BXGF01214	Asparagus cochinchinensis	Asparagus cochinchinensis	Medicinal Plant
BXGF01307	Hemerocallis radix	Hemerocallis radix	Others
BXGF01911	Bupleurum scorzonerifolium	Bupleurum scorzonerifolium	Medicinal Plant
BXGF01941	Scrophularia nodosa	Scrophularia nodosa	Medicinal Plant
BXGF02049	Angelica sinensis	Angelica sinensis	Medicinal Plant
BXGF02268	Ginkgo semen	Ginkgo semen	Others
BXGF02965	Arabidopsis thaliana	Arabidopsis thaliana	Medicinal Plant
BXGF03846	Platymiscium floribundum	Platymiscium floribundum	Others
BXGF03908	Hedysarum multijugum maxim	Hedysarum multijugum maxim	Others
BXGF04232	Caesalpinia crista	Caesalpinia crista	Medicinal Plant
BXGF04842	Angelica acutiloba	Angelica acutiloba	Medicinal Plant
BXGF04875	Bupleurum chinense	Bupleurum chinense	Medicinal Plant
BXGF04981	Bupleurum falcatum	Bupleurum falcatum	Medicinal Plant
BXGF05341	Scrophularia ningpoensis	Scrophularia ningpoensis	Medicinal Plant
BXGF05651	Humulus scandens	Humulus scandens	Human Edible Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}