adisease

Showing entry for Metabolic acidosis

General Disease Information
BXGD Id	BXGD004348
Disease Name	Metabolic acidosis
Disease CUI Id	C0220981
MeSH Codes	C18
Disease Class Name	Nutritional and Metabolic Diseases
Semantic Type	Pathologic Function
Human Phenotype Ontology Id	HP:0001939
Human Phenotype Ontology Term	Abnormality of metabolism/homeostasis
Disease Ontology Id	DOID:0014667
Disease Ontology Class Name	disease of metabolism
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00330	BXGT003910	Pyruvate dehydrogenase protein X component, mitochondrial	8050	reviewed	Enzyme
O43678	BXGT004613	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2	4695	reviewed	Enzyme
O43826	BXGT004629	Glucose-6-phosphate exchanger SLC37A4	2542	reviewed	Transporter
O75251	BXGT005107	NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial	374291	reviewed
O95169	BXGT005356	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial	4714	reviewed	Enzyme
P02730	BXGT005935	Band 3 anion transport protein	6521	reviewed	Transporter
P05062	BXGT006305	Fructose-bisphosphate aldolase B	229	reviewed
P05165	BXGT006334	Propionyl-CoA carboxylase alpha chain, mitochondrial	5095	reviewed	Enzyme
P05166	BXGT006335	Propionyl-CoA carboxylase beta chain, mitochondrial	5096	reviewed	Enzyme
P07902	BXGT006697	Galactose-1-phosphate uridylyltransferase	2592	reviewed	Enzyme
P08235	BXGT006751	Mineralocorticoid receptor	4306	reviewed	Nuclear receptor
P09467	BXGT006893	Fructose-1,6-bisphosphatase 1	2203	reviewed	Enzyme
P09848	BXGT006929	Lactase-phlorizin hydrolase	3938	reviewed	Enzyme
P13866	BXGT007963	Sodium/glucose cotransporter 1	6523	reviewed	Transporter
P19099	BXGT008456	Cytochrome P450 11B2, mitochondrial	1585	reviewed
P21549	BXGT008661	Serine--pyruvate aminotransferase	189	reviewed	Enzyme
P21817	BXGT008693	Ryanodine receptor 1	6261	reviewed	Ion channel
P24752	BXGT008993	Acetyl-CoA acetyltransferase, mitochondrial	38	reviewed	Enzyme
P32754	BXGT009664	4-hydroxyphenylpyruvate dioxygenase	3242	reviewed	Enzyme
P35218	BXGT009796	Carbonic anhydrase 5A, mitochondrial	763	reviewed
P35579	BXGT009852	Myosin-9	4627	reviewed
P35914	BXGT009880	Hydroxymethylglutaryl-CoA lyase, mitochondrial	3155	reviewed	Enzyme
P37088	BXGT009961	Amiloride-sensitive sodium channel subunit alpha	6337	reviewed	Ion channel
P49411	BXGT010703	Elongation factor Tu, mitochondrial	7284	reviewed	Enzyme
P49748	BXGT010733	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	37	reviewed	Enzyme
P49821	BXGT010748	NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial	4723	reviewed
P50747	BXGT010817	Biotin--protein ligase	3141	reviewed	Enzyme
P51168	BXGT010842	Amiloride-sensitive sodium channel subunit beta	6338	reviewed	Ion channel
P51170	BXGT010843	Amiloride-sensitive sodium channel subunit gamma	6340	reviewed	Ion channel
P56556	BXGT011179	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6	4700	reviewed	Enzyme
Q06830	BXGT012894	Peroxiredoxin-1	5052	reviewed	Enzyme
Q07021	BXGT012915	Complement component 1 Q subcomponent-binding protein, mitochondrial	708	reviewed
Q13618	BXGT013382	Cullin-3	8452	reviewed
Q13698	BXGT013392	Voltage-dependent L-type calcium channel subunit alpha-1S	779	reviewed	Ion channel
Q14117	BXGT013443	Dihydropyrimidinase	1807	reviewed	Enzyme
Q16236	BXGT013624	Nuclear factor erythroid 2-related factor 2	4780	reviewed	Enzyme
Q16719	BXGT013662	Kynureninase	8942	reviewed	Enzyme
Q16795	BXGT013671	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial	4704	reviewed	Enzyme
Q2TU34	BXGT014223	Fructose-1,6-bisphosphatase 1	2203	unreviewed
Q6NVY1	BXGT016432	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial	26275	reviewed	Enzyme
Q96EY8	BXGT019655	Corrinoid adenosyltransferase	326625	reviewed	Enzyme
Q96PE7	BXGT019707	Methylmalonyl-CoA epimerase, mitochondrial	84693	reviewed	Enzyme
Q99624	BXGT019942	Sodium-coupled neutral amino acid transporter 3	10991	reviewed	Transporter
Q99714	BXGT019954	3-hydroxyacyl-CoA dehydrogenase type-2	3028	reviewed	Enzyme
Q9H4A3	BXGT020473	Serine/threonine-protein kinase WNK1	65125	reviewed	Kinase
Q9HCC0	BXGT020530	Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial	64087	reviewed	Enzyme
Q9NVS9	BXGT021228	Pyridoxine-5'-phosphate oxidase	55163	reviewed	Enzyme
Q9NX14	BXGT021242	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial	54539	reviewed	Enzyme
Q9P032	BXGT021286	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4	29078	reviewed
Q9ULV0	BXGT021763	Unconventional myosin-Vb	4645	reviewed	Cellular structure
Q9Y375	BXGT022253	Complex I intermediate-associated protein 30, mitochondrial	51103	reviewed
Q9Y4U1	BXGT022285	Methylmalonic aciduria and homocystinuria type C protein	25974	reviewed
P09622	BXGT023116	Dihydrolipoyl dehydrogenase, mitochondrial	1738	reviewed	Enzyme
P07954	BXGT023939	Fumarate hydratase, mitochondrial	2271	reviewed	Enzyme
P98082	BXGT025047	Disabled homolog 2	1601	reviewed	Signaling

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}