Showing entry for ATP-sensitive inward rectifier potassium channel 15


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT019953
Protein NameATP-sensitive inward rectifier potassium channel 15
Uniport IdQ99712
GeneKCNJ15
Gene Id3772
DomainIRK; IRK_C
Pfam PF01007   PF17655  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
5. Organismal Systems 5.4 Digestive system hsa04971 Gastric acid secretion
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:1990573 potassium ion import across plasma membrane
Biological Process GO:0006813 potassium ion transport
Biological Process GO:0034765 regulation of ion transmembrane transport
molecular function GO:0005242 inward rectifier potassium channel activity
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-112314 Neurotransmitter receptors and postsynaptic signal transmission
R-HSA-112315 Transmission across Chemical Synapses
R-HSA-112316 Neuronal System
R-HSA-1296041 Activation of G protein gated Potassium channels
R-HSA-1296059 G protein gated Potassium channels
R-HSA-1296065 Inwardly rectifying K+ channels
R-HSA-1296071 Potassium Channels
R-HSA-977443 GABA receptor activation
R-HSA-977444 GABA B receptor activation
R-HSA-991365 Activation of GABAB receptors
R-HSA-997272 Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0013080 BXGD000797 Down Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0020459 BXGD001394 Hyperinsulinism Nutritional and Metabolic Diseases
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0087031 BXGD003319 Juvenile-Onset Still Disease Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0205682 BXGD004105 Waist-Hip Ratio
C3495559 BXGD018994 Juvenile arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C3714758 BXGD019431 Juvenile psoriatic arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C4552091 BXGD023485 Polyarthritis, Juvenile, Rheumatoid Factor Negative Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C4704862 BXGD023681 Polyarthritis, Juvenile, Rheumatoid Factor Positive Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0046755 Yohimbine 354.19
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein