Showing entry for Juvenile-Onset Still Disease


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD003319
Disease NameJuvenile-Onset Still Disease
Disease CUI IdC0087031
MeSH Codes C17   C05   C20  
Disease Class NameSkin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
A0A024RAV5 BXGT000013 V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b 3845 unreviewed
O00469 BXGT003926 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 5352 reviewed Enzyme
O75923 BXGT005166 Dysferlin 8291 reviewed Transporter
P01100 BXGT005727 Proto-oncogene c-Fos 2353 reviewed Transcription factor
P01116 BXGT005733 GTPase KRas 3845 reviewed Enzyme modulator
P01133 BXGT005736 Pro-epidermal growth factor 1950 reviewed
P01583 BXGT005771 Interleukin-1 alpha 3552 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P01589 BXGT005773 Interleukin-2 receptor subunit alpha 3559 reviewed Receptor
P01889 BXGT005809 HLA class I histocompatibility antigen, B-7 alpha chain 3106 reviewed
P01911 BXGT005816 HLA class II histocompatibility antigen, DRB1-15 beta chain 3123 reviewed Immune response
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 2064 reviewed Kinase
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05412 BXGT006354 Transcription factor AP-1 3725 reviewed Transcription factor
P07225 BXGT006572 Vitamin K-dependent protein S 5627 reviewed
P07358 BXGT006611 Complement component C8 beta chain 732 reviewed
P07996 BXGT006710 Thrombospondin-1 7057 reviewed
P08069 BXGT006723 Insulin-like growth factor 1 receptor 3480 reviewed Kinase
P08514 BXGT006781 Integrin alpha-IIb 3674 reviewed
P08887 BXGT006835 Interleukin-6 receptor subunit alpha 3570 reviewed Signaling
P10646 BXGT007598 Tissue factor pathway inhibitor 7035 reviewed Enzyme modulator
P10909 BXGT007630 Clusterin 1191 reviewed
P11137 BXGT007656 Microtubule-associated protein 2 4133 reviewed
P11169 BXGT007664 Solute carrier family 2, facilitated glucose transporter member 3 6515 reviewed Transporter
P12314 BXGT007798 High affinity immunoglobulin gamma Fc receptor I 2209 reviewed Cell adhesion
P13224 BXGT007890 Platelet glycoprotein Ib beta chain 2812 reviewed
P14174 BXGT007991 Macrophage migration inhibitory factor 4282 reviewed
P14784 BXGT008054 Interleukin-2 receptor subunit beta 3560 reviewed Receptor
P15309 BXGT008105 Prostatic acid phosphatase 55 reviewed Enzyme
P16410 BXGT008224 Cytotoxic T-lymphocyte protein 4 1493 reviewed
P17066 BXGT008279 Heat shock 70 kDa protein 6 3310 reviewed
P17706 BXGT008330 Tyrosine-protein phosphatase non-receptor type 2 5771 reviewed
P18054 BXGT008370 Arachidonate 12-lipoxygenase, 12S-type 239 reviewed Enzyme
P18146 BXGT008384 Early growth response protein 1 1958 reviewed Nucleic acid binding
P25025 BXGT009006 C-X-C chemokine receptor type 2 3579 reviewed G-protein coupled receptor
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P28562 BXGT009270 Dual specificity protein phosphatase 1 1843 reviewed
P29597 BXGT009367 Non-receptor tyrosine-protein kinase TYK2 7297 reviewed Kinase
P31941 BXGT009585 DNA dC->dU-editing enzyme APOBEC-3A 200315 reviewed
P36959 BXGT009948 GMP reductase 1 2766 reviewed
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P41212 BXGT010235 Transcription factor ETV6 2120 reviewed Transcription factor
P42224 BXGT010286 Signal transducer and activator of transcription 1-alpha/beta 6772 reviewed Nucleic acid binding
P43354 BXGT010381 Nuclear receptor subfamily 4 group A member 2 4929 reviewed Nuclear receptor
P51677 BXGT010876 C-C chemokine receptor type 3 1232 reviewed G-protein coupled receptor
P51965 BXGT010911 Ubiquitin-conjugating enzyme E2 E1 7324 reviewed
P53355 BXGT010985 Death-associated protein kinase 1 1612 reviewed Kinase
P57059 BXGT011210 Serine/threonine-protein kinase SIK1 150094 reviewed
P61073 BXGT011352 C-X-C chemokine receptor type 4 7852 reviewed G-protein coupled receptor
P68036 BXGT011572 Ubiquitin-conjugating enzyme E2 L3 7332 reviewed Enzyme
P78380 BXGT011841 Oxidized low-density lipoprotein receptor 1 4973 reviewed
P84022 BXGT012027 Mothers against decapentaplegic homolog 3 4088 reviewed Transcription factor
P98066 BXGT012225 Tumor necrosis factor-inducible gene 6 protein 7130 reviewed
Q00987 BXGT012559 E3 ubiquitin-protein ligase Mdm2 4193 reviewed Nucleic acid binding
Q01196 BXGT012575 Runt-related transcription factor 1 861 reviewed Transcription factor
Q03164 BXGT012700 Histone-lysine N-methyltransferase 2A 4297 reviewed
Q03405 BXGT012713 Urokinase plasminogen activator surface receptor 5329 reviewed
Q13586 BXGT013380 Stromal interaction molecule 1 6786 reviewed
Q13885 BXGT013400 Tubulin beta-2A chain 7280 reviewed Cellular structure
Q15652 BXGT013587 Probable JmjC domain-containing histone demethylation protein 2C 221037 reviewed
Q86VW1 BXGT017621 Solute carrier family 22 member 16 85413 reviewed Transporter
Q99700 BXGT019949 Ataxin-2 6311 reviewed Nucleic acid binding
Q99712 BXGT019953 ATP-sensitive inward rectifier potassium channel 15 3772 reviewed Ion channel
Q9NYY3 BXGT021264 Serine/threonine-protein kinase PLK2 10769 reviewed Kinase
Q9UIQ6 BXGT021721 Leucyl-cystinyl aminopeptidase 4012 reviewed Enzyme
Q9UKE5 BXGT021741 TRAF2 and NCK-interacting protein kinase 23043 reviewed Kinase
Q9UKV0 BXGT021750 Histone deacetylase 9 9734 reviewed Epigenetic regulator
Q9UNF0 BXGT021786 Protein kinase C and casein kinase substrate in neurons protein 2 11252 reviewed Cellular structure
Q9Y5K3 BXGT022294 Choline-phosphate cytidylyltransferase B 9468 reviewed
Q14186 BXGT023367 Transcription factor Dp-1 7027 reviewed Nucleic acid binding
P53539 BXGT023438 Protein fosB 2354 reviewed Transcription factor
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease