Showing entry for Copine-1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT019968
Protein NameCopine-1
Uniport IdQ99829
GeneCPNE1
Gene Id8904
DomainC2; Copine
Pfam PF00168   PF07002  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0071277 cellular response to calcium ion
Biological Process GO:0046474 glycerophospholipid biosynthetic process
Biological Process GO:0006629 lipid metabolic process
Biological Process GO:0043392 negative regulation of DNA binding
Biological Process GO:0010629 negative regulation of gene expression
Biological Process GO:1901223 negative regulation of NIK/NF-kappaB signaling
Biological Process GO:1990138 neuron projection extension
Biological Process GO:0043312 neutrophil degranulation
Biological Process GO:0045666 positive regulation of neuron differentiation
Biological Process GO:0051897 positive regulation of protein kinase B signaling
Biological Process GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway
Biological Process GO:0006508 proteolysis
Biological Process GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling
Biological Process GO:0016192 vesicle-mediated transport
molecular function GO:0005544 calcium-dependent phospholipid binding
molecular function GO:0005509 calcium ion binding
molecular function GO:0004175 endopeptidase activity
molecular function GO:0042802 identical protein binding
molecular function GO:0051059 NF-kappaB binding
molecular function GO:0001786 phosphatidylserine binding
molecular function GO:0005215 transporter activity
cellular component GO:0035577 azurophil granule membrane
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0070062 extracellular exosome
cellular component GO:0016020 membrane
cellular component GO:0031965 nuclear membrane
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-1483206 Glycerophospholipid biosynthesis
R-HSA-1483257 Phospholipid metabolism
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-556833 Metabolism of lipids
R-HSA-6798695 Neutrophil degranulation
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0017612 BXGD001129 Glaucoma, Open-Angle Eye Diseases
C0021704 BXGD001510 Intelligence Behavior and Behavior Mechanisms
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0406208 BXGD008330 Suntan
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0919677 BXGD011435 Protein C measurement
C1168438 BXGD011793 Protein C antigen measurement
C1269955 BXGD012005 Tumor Cell Invasion
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1328504 BXGD012469 Hormone refractory prostate cancer Neoplasms; Male Urogenital Diseases
C1332986 BXGD012574 Childhood Osteosarcoma Neoplasms
C2985280 BXGD018223 Blood Protein Measurement
C3266262 BXGD018600 Multiple Chronic Conditions Pathological Conditions, Signs and Symptoms
C4539944 BXGD023230 SCHIZOPHRENIA 19
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000204 Theophylline 180.16
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein