Showing entry for Glaucoma, Open-Angle


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD001129
Disease NameGlaucoma, Open-Angle
Disease CUI IdC0017612
MeSH Codes C11  
Disease Class NameEye Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id HP:0000478  
Human Phenotype Ontology TermAbnormality of the eye
Disease Ontology Id DOID:7  
Disease Ontology Class Namedisease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O15305 BXGT004152 Phosphomannomutase 2 5373 reviewed Enzyme
O60313 BXGT004871 Dynamin-like 120 kDa protein, mitochondrial 4976 reviewed Enzyme modulator
O60547 BXGT004881 GDP-mannose 4,6 dehydratase 2762 reviewed Enzyme
O95363 BXGT005375 Phenylalanine--tRNA ligase, mitochondrial 10667 reviewed Enzyme
O96017 BXGT005415 Serine/threonine-protein kinase Chk2 11200 reviewed Kinase
P01019 BXGT005717 Angiotensinogen 183 reviewed Enzyme modulator
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P03956 BXGT006120 Interstitial collagenase 4312 reviewed Enzyme
P04278 BXGT006182 Sex hormone-binding globulin 6462 reviewed
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P05121 BXGT006320 Plasminogen activator inhibitor 1 5054 reviewed Enzyme modulator
P07550 BXGT006636 Beta-2 adrenergic receptor 154 reviewed G-protein coupled receptor
P07900 BXGT006696 Heat shock protein HSP 90-alpha 3320 reviewed Chaperone
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P08588 BXGT006795 Beta-1 adrenergic receptor 153 reviewed G-protein coupled receptor
P09488 BXGT006899 Glutathione S-transferase Mu 1 2944 reviewed
P0DMV8 BXGT007509 Heat shock 70 kDa protein 1A 3304 reviewed
P0DMV9 BXGT007510 Heat shock 70 kDa protein 1B 3304 reviewed
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10826 BXGT007622 Retinoic acid receptor beta 5915 reviewed Nuclear receptor
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P12830 BXGT007852 Cadherin-1 999 reviewed
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P15121 BXGT008083 Aldo-keto reductase family 1 member B1 231 reviewed Enzyme
P16442 BXGT008227 Histo-blood group ABO system transferase 28 reviewed Enzyme
P17643 BXGT008323 5,6-dihydroxyindole-2-carboxylic acid oxidase 7306 reviewed Enzyme
P23560 BXGT008883 Brain-derived neurotrophic factor 627 reviewed Signaling
P23975 BXGT008935 Sodium-dependent noradrenaline transporter 6530 reviewed Transporter
P27169 BXGT009161 Serum paraoxonase/arylesterase 1 5444 reviewed
P28907 BXGT009301 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 952 reviewed Enzyme
P30711 BXGT009460 Glutathione S-transferase theta-1 2952 reviewed
P34130 BXGT009752 Neurotrophin-4 4909 reviewed Signaling
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35555 BXGT009845 Fibrillin-1 2200 reviewed Calcium-binding protein
P38936 BXGT010074 Cyclin-dependent kinase inhibitor 1 1026 reviewed
P39019 BXGT010082 40S ribosomal protein S19 6223 reviewed Nucleic acid binding
P40967 BXGT010212 Melanocyte protein PMEL 6490 reviewed Signaling
P42898 BXGT010344 Methylenetetrahydrofolate reductase 4524 reviewed
P43115 BXGT010356 Prostaglandin E2 receptor EP3 subtype 5733 reviewed G-protein coupled receptor
P48023 BXGT010604 Tumor necrosis factor ligand superfamily member 6 356 reviewed Signaling
Q03518 BXGT012723 Antigen peptide transporter 1 6890 reviewed Transporter
Q14116 BXGT013442 Interleukin-18 3606 reviewed
Q15389 BXGT013564 Angiopoietin-1 284 reviewed Signaling
Q16611 BXGT013644 Bcl-2 homologous antagonist/killer 578 reviewed Signaling
Q16678 BXGT013656 Cytochrome P450 1B1 1545 reviewed Enzyme
Q92731 BXGT019366 Estrogen receptor beta 2100 reviewed Nuclear receptor
Q99700 BXGT019949 Ataxin-2 6311 reviewed Nucleic acid binding
Q99829 BXGT019968 Copine-1 8904 reviewed
Q99972 BXGT019979 Myocilin 4653 reviewed Cellular structure
Q9H816 BXGT020494 5' exonuclease Apollo 64858 reviewed
Q9NNW7 BXGT021139 Thioredoxin reductase 2, mitochondrial 10587 reviewed Enzyme
Q9NP56 BXGT021142 cAMP-specific 3',5'-cyclic phosphodiesterase 7B 27115 reviewed
Q9P212 BXGT021297 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 51196 reviewed Enzyme
Q9UGJ0 BXGT021683 5'-AMP-activated protein kinase subunit gamma-2 51422 reviewed Enzyme modulator
Q9UHD2 BXGT021697 Serine/threonine-protein kinase TBK1 29110 reviewed Kinase
Q16760 BXGT022666 Diacylglycerol kinase delta 8527 reviewed Enzyme
Q9H694 BXGT024116 Protein bicaudal C homolog 1 80114 reviewed Transporter
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease