Showing entry for Selenoprotein S


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT020110
Protein NameSelenoprotein S
Uniport IdQ9BQE4
GeneSELENOS
Gene Id55829
DomainSelenoprotein_S
Pfam PF06936  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
2. Genetic Information Processing 2.3 Folding, sorting and degradation hsa04141 Protein processing in endoplasmic reticulum
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0045454 cell redox homeostasis
Biological Process GO:0032869 cellular response to insulin stimulus
Biological Process GO:0071222 cellular response to lipopolysaccharide
Biological Process GO:0034599 cellular response to oxidative stress
Biological Process GO:0030968 endoplasmic reticulum unfolded protein response
Biological Process GO:0006983 ER overload response
Biological Process GO:0045184 establishment of protein localization
Biological Process GO:0002865 negative regulation of acute inflammatory response to antigenic stimulus
Biological Process GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
Biological Process GO:0046325 negative regulation of glucose import
Biological Process GO:0045719 negative regulation of glycogen biosynthetic process
Biological Process GO:0050728 negative regulation of inflammatory response
Biological Process GO:0032715 negative regulation of interleukin-6 production
Biological Process GO:2000110 negative regulation of macrophage apoptotic process
Biological Process GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process
Biological Process GO:0032720 negative regulation of tumor necrosis factor production
Biological Process GO:0016567 protein ubiquitination
Biological Process GO:0006111 regulation of gluconeogenesis
Biological Process GO:0080164 regulation of nitric oxide metabolic process
Biological Process GO:0009749 response to glucose
Biological Process GO:0051775 response to redox state
Biological Process GO:0030970 retrograde protein transport, ER to cytosol
Biological Process GO:0030433 ubiquitin-dependent ERAD pathway
molecular function GO:0016209 antioxidant activity
molecular function GO:0051117 ATPase binding
molecular function GO:0019899 enzyme binding
molecular function GO:0038023 signaling receptor activity
molecular function GO:1990381 ubiquitin-specific protease binding
cellular component GO:0005881 cytoplasmic microtubule
cellular component GO:0036513 Derlin-1 retrotranslocation complex
cellular component GO:0036502 Derlin-1-VIMP complex
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0005789 endoplasmic reticulum membrane
cellular component GO:0030176 integral component of endoplasmic reticulum membrane
cellular component GO:0034362 low-density lipoprotein particle
cellular component GO:0005886 plasma membrane
cellular component GO:0034361 very-low-density lipoprotein particle
Reactome
Pathway Id Pathway Name
R-HSA-392499 Metabolism of proteins
R-HSA-597592 Post-translational protein modification
R-HSA-8852135 Protein ubiquitination
R-HSA-8866654 E3 ubiquitin ligases ubiquitinate target proteins
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001342 BXGD000042 Acute periodontitis Stomatognathic Diseases
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007222 BXGD000454 Cardiovascular Diseases Cardiovascular Diseases
C0007820 BXGD000491 Cerebrovascular Disorders Nervous System Diseases; Cardiovascular Diseases
C0009319 BXGD000596 Colitis Digestive System Diseases
C0009324 BXGD000597 Ulcerative Colitis Digestive System Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0010054 BXGD000647 Coronary Arteriosclerosis Cardiovascular Diseases
C0010068 BXGD000648 Coronary heart disease Cardiovascular Diseases
C0011615 BXGD000738 Dermatitis, Atopic Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Immune System Diseases
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011854 BXGD000753 Diabetes Mellitus, Insulin-Dependent Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0013595 BXGD000858 Eczema Skin and Connective Tissue Diseases
C0020877 BXGD001471 Ileitis Digestive System Diseases
C0021368 BXGD001502 Inflammation Pathological Conditions, Signs and Symptoms
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0021670 BXGD001509 insulinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0025517 BXGD001875 Metabolic Diseases Nutritional and Metabolic Diseases
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0031106 BXGD002283 Aggressive Periodontitis Stomatognathic Diseases
C0033578 BXGD002408 Prostatic Neoplasms Neoplasms; Male Urogenital Diseases
C0036690 BXGD002632 Septicemia Pathological Conditions, Signs and Symptoms; Infections
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0040128 BXGD002844 Thyroid Diseases Endocrine System Diseases
C0221757 BXGD004472 alpha 1-Antitrypsin Deficiency Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Respiratory Tract Diseases
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0342649 BXGD007522 Vascular calcification Nutritional and Metabolic Diseases
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0524620 BXGD009236 Metabolic Syndrome X Nutritional and Metabolic Diseases
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0677607 BXGD009721 Hashimoto Disease Endocrine System Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0856169 BXGD011096 Endothelial dysfunction
C0948008 BXGD011499 Ischemic stroke Nervous System Diseases; Cardiovascular Diseases
C1096293 BXGD011616 Macroangiopathy
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1956346 BXGD016627 Coronary Artery Disease Cardiovascular Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2745963 BXGD017571 Kashin-Beck Disease Musculoskeletal Diseases
C3501835 BXGD019026 alpha-1-Antitrypsin Deficiency, Autosomal Recessive Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Respiratory Tract Diseases
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0003705 Chloride 35.45
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein