Showing entry for Intersectin-2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT021278
Protein NameIntersectin-2
Uniport IdQ9NZM3
GeneITSN2
Gene Id50618
DomainC2; EF-hand_4; PH_13; RhoGEF; SH3_1; SH3_2; SH3_9
Pfam PF00168   PF12763   PF16652   PF00621   PF00018   PF07653   PF14604  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0150007 clathrin-dependent synaptic vesicle endocytosis
Biological Process GO:0006897 endocytosis
Biological Process GO:0016197 endosomal transport
Biological Process GO:1903861 positive regulation of dendrite extension
Biological Process GO:0016032 viral process
molecular function GO:0005509 calcium ion binding
molecular function GO:0005085 guanyl-nucleotide exchange factor activity
molecular function GO:0060090 molecular adaptor activity
cellular component GO:0005813 centrosome
cellular component GO:0005905 clathrin-coated pit
cellular component GO:0005737 cytoplasm
cellular component GO:0070062 extracellular exosome
cellular component GO:0098793 presynapse
Reactome
Pathway Id Pathway Name
R-HSA-199991 Membrane Trafficking
R-HSA-5653656 Vesicle-mediated transport
R-HSA-8856825 Cargo recognition for clathrin-mediated endocytosis
R-HSA-8856828 Clathrin-mediated endocytosis
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0005586 BXGD000315 Bipolar Disorder Mental Disorders
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0011570 BXGD000729 Mental Depression Behavior and Behavior Mechanisms
C0011581 BXGD000733 Depressive disorder Mental Disorders
C0017250 BXGD001106 Psychosexual identity disorder Mental Disorders; Behavior and Behavior Mechanisms
C0023508 BXGD001675 White Blood Cell Count procedure
C0027643 BXGD002007 Neoplasm Recurrence, Local Pathological Conditions, Signs and Symptoms; Neoplasms
C0027726 BXGD002030 Nephrotic Syndrome Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0030193 BXGD002191 Pain Pathological Conditions, Signs and Symptoms
C0031212 BXGD002295 Personality Disorders Mental Disorders
C0033578 BXGD002408 Prostatic Neoplasms Neoplasms; Male Urogenital Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0038586 BXGD002772 Substance Use Disorders Chemically-Induced Disorders; Mental Disorders
C0042769 BXGD002999 Virus Diseases Infections
C0085635 BXGD003217 Photopsia Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0086981 BXGD003317 Sicca Syndrome Eye Diseases; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases; Stomatognathic Diseases
C0152244 BXGD003571 Bone Cysts, Aneurysmal Neoplasms; Musculoskeletal Diseases
C0302527 BXGD006850 Pathological personality NOS Mental Disorders
C0344315 BXGD007666 Depressed mood Behavior and Behavior Mechanisms
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0522254 BXGD009199 Analgesic Overuse Headache Nervous System Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0686346 BXGD009831 Gender Dysphoria Mental Disorders
C1257931 BXGD011815 Mammary Neoplasms, Human Neoplasms; Skin and Connective Tissue Diseases
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1527336 BXGD013271 Sjogren's Syndrome Eye Diseases; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases; Stomatognathic Diseases
C3160718 BXGD018468 PARKINSON DISEASE, LATE-ONSET
C3806402 BXGD019507 EPILEPSY, FOCAL, WITH SPEECH DISORDER AND WITH OR WITHOUT MENTAL RETARDATION
C4704874 BXGD023682 Mammary Carcinoma, Human Neoplasms; Skin and Connective Tissue Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0003705 Chloride 35.45
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein