Showing entry for Substance Use Disorders


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD002772
Disease NameSubstance Use Disorders
Disease CUI IdC0038586
MeSH Codes C25   F03  
Disease Class NameChemically-Induced Disorders; Mental Disorders
Semantic TypeMental or Behavioral Dysfunction
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
A1Z1Q3 BXGT001069 ADP-ribose glycohydrolase MACROD2 140733 reviewed
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O00519 BXGT003934 Fatty-acid amide hydrolase 1 2166 reviewed
O15439 BXGT004169 Multidrug resistance-associated protein 4 10257 reviewed Transporter
O43612 BXGT004605 Orexin 3060 reviewed
O75628 BXGT005140 GTP-binding protein REM 1 28954 reviewed
O75751 BXGT005150 Solute carrier family 22 member 3 6581 reviewed Transporter
P00352 BXGT005510 Retinal dehydrogenase 1 216 reviewed Enzyme
P00505 BXGT005560 Aspartate aminotransferase, mitochondrial 2806 reviewed
P01138 BXGT005738 Beta-nerve growth factor 4803 reviewed Signaling
P01189 BXGT005742 Pro-opiomelanocortin 5443 reviewed
P01275 BXGT005747 Glucagon 2641 reviewed
P01303 BXGT005748 Pro-neuropeptide Y 4852 reviewed Signaling
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P04150 BXGT006154 Glucocorticoid receptor 2908 reviewed Nuclear receptor
P05026 BXGT006296 Sodium/potassium-transporting ATPase subunit beta-1 481 reviewed Transporter
P05231 BXGT006345 Interleukin-6 3569 reviewed
P06213 BXGT006425 Insulin receptor 3643 reviewed Kinase
P06850 BXGT006511 Corticoliberin 1392 reviewed Signaling
P07814 BXGT006680 Bifunctional glutamate/proline--tRNA ligase 2058 reviewed Enzyme
P08172 BXGT006737 Muscarinic acetylcholine receptor M2 1129 reviewed G-protein coupled receptor
P08581 BXGT006794 Hepatocyte growth factor receptor 4233 reviewed Kinase
P08908 BXGT006837 5-hydroxytryptamine receptor 1A 3350 reviewed G-protein coupled receptor
P09038 BXGT006851 Fibroblast growth factor 2 2247 reviewed Signaling
P09172 BXGT006865 Dopamine beta-hydroxylase 1621 reviewed
P0DP23 BXGT007520 Calmodulin-1 808 reviewed
P0DP24 BXGT007521 Calmodulin-2 808 reviewed
P10586 BXGT007581 Receptor-type tyrosine-protein phosphatase F 5792 reviewed Enzyme
P10635 BXGT007595 Cytochrome P450 2D6 1565 reviewed
P13569 BXGT007923 Cystic fibrosis transmembrane conductance regulator 1080 reviewed Ion channel
P14416 BXGT008011 D(2) dopamine receptor 1813 reviewed G-protein coupled receptor
P14616 BXGT008026 Insulin receptor-related protein 3645 reviewed Kinase
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P18089 BXGT008379 Alpha-2B adrenergic receptor 151 reviewed G-protein coupled receptor
P21397 BXGT008644 Amine oxidase [flavin-containing] A 4128 reviewed
P21554 BXGT008662 Cannabinoid receptor 1 1268 reviewed G-protein coupled receptor
P21917 BXGT008707 D(4) dopamine receptor 1815 reviewed G-protein coupled receptor
P21964 BXGT008714 Catechol O-methyltransferase 1312 reviewed Enzyme
P23560 BXGT008883 Brain-derived neurotrophic factor 627 reviewed Signaling
P24723 BXGT008989 Protein kinase C eta type 5583 reviewed Kinase
P25101 BXGT009018 Endothelin-1 receptor 1909 reviewed G-protein coupled receptor
P27708 BXGT009202 CAD protein 790 reviewed Enzyme
P28222 BXGT009238 5-hydroxytryptamine receptor 1B 3351 reviewed G-protein coupled receptor
P28223 BXGT009239 5-hydroxytryptamine receptor 2A 3356 reviewed G-protein coupled receptor
P30532 BXGT009433 Neuronal acetylcholine receptor subunit alpha-5 1138 reviewed Ion channel
P30926 BXGT009482 Neuronal acetylcholine receptor subunit beta-4 1143 reviewed Ion channel
P31391 BXGT009535 Somatostatin receptor type 4 6754 reviewed G-protein coupled receptor
P31645 BXGT009558 Sodium-dependent serotonin transporter 6532 reviewed Transporter
P34972 BXGT009779 Cannabinoid receptor 2 1269 reviewed G-protein coupled receptor
P35348 BXGT009814 Alpha-1A adrenergic receptor 148 reviewed G-protein coupled receptor
P35372 BXGT009823 Mu-type opioid receptor 4988 reviewed G-protein coupled receptor
P35462 BXGT009835 D(3) dopamine receptor 1814 reviewed G-protein coupled receptor
P37288 BXGT009977 Vasopressin V1a receptor 552 reviewed G-protein coupled receptor
P41143 BXGT010223 Delta-type opioid receptor 4985 reviewed G-protein coupled receptor
P41145 BXGT010225 Kappa-type opioid receptor 4986 reviewed G-protein coupled receptor
P41212 BXGT010235 Transcription factor ETV6 2120 reviewed Transcription factor
P41594 BXGT010266 Metabotropic glutamate receptor 5 2915 reviewed G-protein coupled receptor
P42357 BXGT010306 Histidine ammonia-lyase 3034 reviewed
P43220 BXGT010367 Glucagon-like peptide 1 receptor 2740 reviewed G-protein coupled receptor
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 1137 reviewed Ion channel
P47898 BXGT010594 5-hydroxytryptamine receptor 5A 3361 reviewed G-protein coupled receptor
P48058 BXGT010614 Glutamate receptor 4 2893 reviewed Ion channel
P49789 BXGT010742 Bis(5'-adenosyl)-triphosphatase 2272 reviewed
Q01959 BXGT012624 Sodium-dependent dopamine transporter 6531 reviewed Transporter
Q02156 BXGT012639 Protein kinase C epsilon type 5581 reviewed Kinase
Q12908 BXGT013278 Ileal sodium/bile acid cotransporter 6555 reviewed Transporter
Q13002 BXGT013303 Glutamate receptor ionotropic, kainate 2 2898 reviewed Ion channel
Q13255 BXGT013332 Metabotropic glutamate receptor 1 2911 reviewed G-protein coupled receptor
Q13451 BXGT013356 Peptidyl-prolyl cis-trans isomerase FKBP5 2289 reviewed Enzyme
Q14123 BXGT013445 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C 5137 reviewed
Q14416 BXGT013468 Metabotropic glutamate receptor 2 2912 reviewed G-protein coupled receptor
Q14831 BXGT013506 Metabotropic glutamate receptor 7 2917 reviewed G-protein coupled receptor
Q16555 BXGT013638 Dihydropyrimidinase-related protein 2 1808 reviewed Enzyme
Q59FK2 BXGT015276 Selenocysteine lyase variant 51540 unreviewed
Q5KU26 BXGT015462 Collectin-12 81035 reviewed Extracellular structure
Q92499 BXGT019350 ATP-dependent RNA helicase DDX1 1653 reviewed
Q96I15 BXGT019674 Selenocysteine lyase 51540 reviewed Enzyme
Q96QU1 BXGT019721 Protocadherin-15 65217 reviewed
Q99685 BXGT019948 Monoglyceride lipase 11343 reviewed Enzyme
Q9BUB5 BXGT020133 MAP kinase-interacting serine/threonine-protein kinase 1 8569 reviewed Kinase
Q9H227 BXGT020447 Cytosolic beta-glucosidase 57733 reviewed Enzyme
Q9H2G2 BXGT020452 STE20-like serine/threonine-protein kinase 9748 reviewed Kinase
Q9HAR2 BXGT020506 Adhesion G protein-coupled receptor L3 23284 reviewed G-protein coupled receptor
Q9NQX4 BXGT021173 Unconventional myosin-Vc 55930 reviewed Cellular structure
Q9NT68 BXGT021210 Teneurin-2 57451 reviewed
Q9NVD7 BXGT021223 Alpha-parvin 55742 reviewed Cellular structure
Q9NZM3 BXGT021278 Intersectin-2 50618 reviewed Enzyme modulator
Q9NZQ7 BXGT021281 Programmed cell death 1 ligand 1 29126 reviewed Receptor
Q8NEU8 BXGT022976 DCC-interacting protein 13-beta 55198 reviewed
P0DP25 BXGT024595 Calmodulin-3 808 reviewed
P27918 BXGT025485 Properdin 5199 reviewed
O43172 BXGT026158 U4/U6 small nuclear ribonucleoprotein Prp4 9128 reviewed Nucleic acid binding
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease