Showing entry for Sodium-coupled neutral amino acid transporter 2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT022647
Protein NameSodium-coupled neutral amino acid transporter 2
Uniport IdQ96QD8
GeneSLC38A2
Gene Id54407
Domain_trans
Pfam PF01490  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
5. Organismal Systems 5.6 Nervous system hsa04724 Glutamatergic synapse
5. Organismal Systems 5.6 Nervous system hsa04727 GABAergic synapse
5. Organismal Systems 5.4 Digestive system hsa04974 Protein digestion and absorption
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0032328 alanine transport
Biological Process GO:0003333 amino acid transmembrane transport
Biological Process GO:0006865 amino acid transport
Biological Process GO:0034198 cellular response to amino acid starvation
Biological Process GO:1903841 cellular response to arsenite(3-)
Biological Process GO:0071260 cellular response to mechanical stimulus
Biological Process GO:0021987 cerebral cortex development
Biological Process GO:0007565 female pregnancy
Biological Process GO:0014047 glutamate secretion
Biological Process GO:0006868 glutamine transport
Biological Process GO:0031460 glycine betaine transport
Biological Process GO:0015825 L-serine transport
Biological Process GO:0015804 neutral amino acid transport
Biological Process GO:0010628 positive regulation of gene expression
Biological Process GO:0033120 positive regulation of RNA splicing
Biological Process GO:0080135 regulation of cellular response to stress
Biological Process GO:0150104 transport across blood-brain barrier
molecular function GO:0015171 amino acid transmembrane transporter activity
molecular function GO:0015186 L-glutamine transmembrane transporter activity
molecular function GO:0015194 L-serine transmembrane transporter activity
molecular function GO:0005295 neutral amino acid:sodium symporter activity
cellular component GO:0030424 axon
cellular component GO:0005903 brush border
cellular component GO:0005737 cytoplasm
cellular component GO:0030425 dendrite
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0043025 neuronal cell body
cellular component GO:0005886 plasma membrane
cellular component GO:0042383 sarcolemma
Reactome
Pathway Id Pathway Name
R-HSA-112310 Neurotransmitter release cycle
R-HSA-112315 Transmission across Chemical Synapses
R-HSA-112316 Neuronal System
R-HSA-210500 Glutamate Neurotransmitter Release Cycle
R-HSA-352230 Amino acid transport across the plasma membrane
R-HSA-382551 Transport of small molecules
R-HSA-425393 Transport of inorganic cations/anions and amino acids/oligopeptides
R-HSA-425407 SLC-mediated transmembrane transport
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0011853 BXGD000752 Diabetes Mellitus, Experimental Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0013336 BXGD000815 Dwarfism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases
C0015934 BXGD001026 Fetal Growth Retardation Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0016052 BXGD001040 Fibromuscular Dysplasia Cardiovascular Diseases
C0018553 BXGD001203 Hamartoma Syndrome, Multiple Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms
C0020459 BXGD001394 Hyperinsulinism Nutritional and Metabolic Diseases
C0025202 BXGD001832 melanoma Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027708 BXGD002025 Nephroblastoma Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0040021 BXGD002834 Thromboangiitis Obliterans Cardiovascular Diseases
C0238288 BXGD004905 Muscular Dystrophy, Facioscapulohumeral Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0270824 BXGD006113 Visual seizure Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C1168401 BXGD011792 Squamous cell carcinoma of the head and neck Neoplasms
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1333015 BXGD012581 Childhood Kidney Wilms Tumor Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C3853540 BXGD019820 Aspirin exacerbated respiratory disease Pathological Conditions, Signs and Symptoms; Infections; Respiratory Tract Diseases; Immune System Diseases; Chemically-Induced Disorders; Otorhinolaryngologic Diseases
C4049259 BXGD021916 Hormone refractory breast cancer Neoplasms; Skin and Connective Tissue Diseases
C4281559 BXGD022411 FRONTOMETAPHYSEAL DYSPLASIA 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C4285716 BXGD022449 Melatonin deficiency
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000458 L-Asparagine 132.12
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein