Showing entry for Thromboangiitis Obliterans



                               
General Disease Information
BXGD IdBXGD002834
Disease NameThromboangiitis Obliterans
Disease CUI IdC0040021
MeSH Codes C14  
Disease Class NameCardiovascular Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:7  
Disease Ontology Class Namedisease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00182 BXGT003889 Galectin-9 3965 reviewed Signaling
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O14672 BXGT004081 Disintegrin and metalloproteinase domain-containing protein 10 102 reviewed
O94813 BXGT005337 Slit homolog 2 protein 9353 reviewed
P00734 BXGT005630 Prothrombin 2147 reviewed Enzyme
P01042 BXGT005722 Kininogen-1 3827 reviewed Enzyme modulator
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01579 BXGT005770 Interferon gamma 3458 reviewed
P01583 BXGT005771 Interleukin-1 alpha 3552 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P01889 BXGT005809 HLA class I histocompatibility antigen, B-7 alpha chain 3106 reviewed
P01909 BXGT005815 HLA class II histocompatibility antigen, DQ alpha 1 chain 3117 reviewed Immune response
P01911 BXGT005816 HLA class II histocompatibility antigen, DRB1-15 beta chain 3123 reviewed Immune response
P02647 BXGT005908 Apolipoprotein A-I 335 reviewed
P04150 BXGT006154 Glucocorticoid receptor 2908 reviewed Nuclear receptor
P04440 BXGT006216 HLA class II histocompatibility antigen, DP beta 1 chain 3115 reviewed Immune response
P05121 BXGT006320 Plasminogen activator inhibitor 1 5054 reviewed Enzyme modulator
P05230 BXGT006344 Fibroblast growth factor 1 2246 reviewed Signaling
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05362 BXGT006350 Intercellular adhesion molecule 1 3383 reviewed
P05771 BXGT006384 Protein kinase C beta type 5579 reviewed Kinase
P08069 BXGT006723 Insulin-like growth factor 1 receptor 3480 reviewed Kinase
P08254 BXGT006758 Stromelysin-1 4314 reviewed Enzyme
P08575 BXGT006793 Receptor-type tyrosine-protein phosphatase C 5788 reviewed Enzyme
P09429 BXGT006889 High mobility group protein B1 3146 reviewed Nucleic acid binding
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P13501 BXGT007917 C-C motif chemokine 5 6352 reviewed Signaling
P14210 BXGT007994 Hepatocyte growth factor 3082 reviewed Enzyme
P15090 BXGT008079 Fatty acid-binding protein, adipocyte 2167 reviewed
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P16070 BXGT008186 CD44 antigen 960 reviewed
P16473 BXGT008234 Thyrotropin receptor 7253 reviewed G-protein coupled receptor
P16581 BXGT008245 E-selectin 6401 reviewed
P17252 BXGT008294 Protein kinase C alpha type 5578 reviewed Kinase
P17948 BXGT008358 Vascular endothelial growth factor receptor 1 2321 reviewed Kinase
P19320 BXGT008470 Vascular cell adhesion protein 1 7412 reviewed
P25942 BXGT009079 Tumor necrosis factor receptor superfamily member 5 958 reviewed
P28300 BXGT009243 Protein-lysine 6-oxidase 4015 reviewed
P29474 BXGT009352 Nitric oxide synthase, endothelial 4846 reviewed
P29965 BXGT009388 CD40 ligand 959 reviewed Signaling
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P34998 BXGT009781 Corticotropin-releasing factor receptor 1 1394 reviewed
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P42224 BXGT010286 Signal transducer and activator of transcription 1-alpha/beta 6772 reviewed Nucleic acid binding
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P43405 BXGT010386 Tyrosine-protein kinase SYK 6850 reviewed Kinase
P45983 BXGT010494 Mitogen-activated protein kinase 8 5599 reviewed Kinase
P46531 BXGT010526 Neurogenic locus notch homolog protein 1 4851 reviewed
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P56945 BXGT011206 Breast cancer anti-estrogen resistance protein 1 9564 reviewed
P61011 BXGT011346 Signal recognition particle 54 kDa protein 6729 reviewed Nucleic acid binding
P62736 BXGT011452 Actin, aortic smooth muscle 59 reviewed Cellular structure
P78504 BXGT011844 Protein jagged-1 182 reviewed
Q13285 BXGT013335 Steroidogenic factor 1 2516 reviewed Nuclear receptor
Q14289 BXGT013459 Protein-tyrosine kinase 2-beta 2185 reviewed Kinase
Q14469 BXGT013473 Transcription factor HES-1 3280 reviewed Transcription factor
Q15109 BXGT013537 Advanced glycosylation end product-specific receptor 177 reviewed Receptor
Q15796 BXGT013599 Mothers against decapentaplegic homolog 2 4087 reviewed Transcription factor
Q53EL6 BXGT015008 Programmed cell death protein 4 27250 reviewed Nucleic acid binding
Q5VWK5 BXGT015891 Interleukin-23 receptor 149233 reviewed Signaling
Q8TDQ0 BXGT018810 Hepatitis A virus cellular receptor 2 84868 reviewed
Q96P20 BXGT019704 NACHT, LRR and PYD domains-containing protein 3 114548 reviewed
Q99836 BXGT019970 Myeloid differentiation primary response protein MyD88 4615 reviewed Enzyme modulator
Q9HBE5 BXGT020518 Interleukin-21 receptor 50615 reviewed Receptor
Q9Y251 BXGT022215 Heparanase 10855 reviewed Enzyme
Q96QD8 BXGT022647 Sodium-coupled neutral amino acid transporter 2 54407 reviewed Transporter
P04439 BXGT022649 HLA class I histocompatibility antigen, A-3 alpha chain 3105 reviewed
Q16552 BXGT023419 Interleukin-17A 3605 reviewed
Q96QC4 BXGT023878 MHC class I polypeptide-related sequence A 100507436 unreviewed
Q9UQE7 BXGT025899 Structural maintenance of chromosomes protein 3 9126 reviewed
P00403 BXGT026137 Cytochrome c oxidase subunit 2 4513 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease