Showing entry for Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT022664
Protein NameElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial
Uniport IdQ16134
GeneETFDH
Gene Id2110
DomainETF_QO; Thi4
Pfam -  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0022900 electron transport chain
Biological Process GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase
Biological Process GO:0022904 respiratory electron transport chain
Biological Process GO:0006979 response to oxidative stress
molecular function GO:0051539 4 iron, 4 sulfur cluster binding
molecular function GO:0009055 electron transfer activity
molecular function GO:0004174 electron-transferring-flavoprotein dehydrogenase activity
molecular function GO:0050660 flavin adenine dinucleotide binding
molecular function GO:0046872 metal ion binding
molecular function GO:0016491 oxidoreductase activity
molecular function GO:0043783 oxidoreductase activity, oxidizing metal ions with flavin as acceptor
molecular function GO:0048038 quinone binding
molecular function GO:0048039 ubiquinone binding
cellular component GO:0031305 integral component of mitochondrial inner membrane
cellular component GO:0005759 mitochondrial matrix
cellular component GO:0031966 mitochondrial membrane
Reactome
Pathway Id Pathway Name
R-HSA-1428517 The citric acid (TCA) cycle and respiratory electron transport
R-HSA-1430728 Metabolism
R-HSA-163200 Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
R-HSA-611105 Respiratory electron transport
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001122 BXGD000023 Acidosis Nutritional and Metabolic Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0015672 BXGD001011 Fatigue Pathological Conditions, Signs and Symptoms
C0015695 BXGD001013 Fatty Liver Digestive System Diseases
C0017639 BXGD001133 Gliosis Pathological Conditions, Signs and Symptoms
C0017979 BXGD001159 Glycosuria Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0019209 BXGD001305 Hepatomegaly Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0020615 BXGD001445 Hypoglycemia Nutritional and Metabolic Diseases
C0020617 BXGD001446 Hypoglycemic coma Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases; Nervous System Diseases; Endocrine System Diseases
C0022346 BXGD001537 Icterus Pathological Conditions, Signs and Symptoms
C0022680 BXGD001576 Polycystic Kidney Diseases Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0025517 BXGD001875 Metabolic Diseases Nutritional and Metabolic Diseases
C0026827 BXGD001936 Muscle hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0026848 BXGD001941 Myopathy Musculoskeletal Diseases; Nervous System Diseases
C0027497 BXGD001993 Nausea Pathological Conditions, Signs and Symptoms
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0030552 BXGD002238 Paresis Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0042963 BXGD003018 Vomiting Pathological Conditions, Signs and Symptoms
C0151786 BXGD003475 Muscle Weakness Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0221355 BXGD004447 Macrocephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0239676 BXGD004989 High forehead
C0265783 BXGD005575 Congenital hypoplasia of lung Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases
C0266483 BXGD005680 Pachygyria Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0268238 BXGD005862 Triglyceride storage disease with ichthyosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Nervous System Diseases
C0268594 BXGD005998 Glutaric aciduria
C0268596 BXGD006000 Multiple Acyl Coenzyme A Dehydrogenase Deficiency Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0342788 BXGD007552 Renal carnitine transport defect Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases; Cardiovascular Diseases
C0342790 BXGD007553 Carnitine palmitoyl transferase 2 deficiency Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0369183 BXGD007960 Erythrocyte Mean Corpuscular Hemoglobin Test
C0410214 BXGD008420 Myopathy with Abnormal Lipid Metabolism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Musculoskeletal Diseases; Nervous System Diseases
C0410916 BXGD008452 Neonatal Death Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications
C0423113 BXGD008473 Telecanthus Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0424503 BXGD008532 Dysmorphic facies
C0476237 BXGD008983 Metabolic symptoms
C0476273 BXGD008986 Respiratory distress Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases
C0546389 BXGD009336 Hepatic periportal necrosis
C0744356 BXGD010094 Abnormality of the genital system Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0857379 BXGD011148 Abnormality of the pinna
C1261502 BXGD011856 Finding of Mean Corpuscular Hemoglobin
C1836542 BXGD014129 Depressed nasal bridge
C1839603 BXGD014388 Proximal tubulopathy Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1843920 BXGD014619 COENZYME Q10 DEFICIENCY Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases; Musculoskeletal Diseases; Nervous System Diseases
C1847868 BXGD014893 Generalized aminoaciduria
C1853136 BXGD015305 Neutral Lipid Storage Disease with Myopathy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Musculoskeletal Diseases; Nervous System Diseases
C1856401 BXGD015600 Glutaric Aciduria IIA Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C1856403 BXGD015601 Glutaric Aciduria IIB Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C1856405 BXGD015602 Glutaric Aciduria IIC Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C1859308 BXGD015871 PREMATURE CENTROMERE DIVISION
C1865353 BXGD016318 Ethylmalonic aciduria
C1866134 BXGD016378 Wide anterior fontanel
C1969144 BXGD016760 Renal cortical cysts
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2711227 BXGD017478 Steatohepatitis Digestive System Diseases
C2985280 BXGD018223 Blood Protein Measurement
C3278156 BXGD018731 GLUTARIC ACIDEMIA IIC
C4016438 BXGD020334 GLUTARIC ACIDEMIA IIC, LATE-ONSET
C4025586 BXGD021679 Electron transfer flavoprotein-ubiquinone oxidoreductase defect
C4025603 BXGD021689 Glutaric acidemia Nutritional and Metabolic Diseases
C4551720 BXGD023400 Primary Ciliary Dyskinesia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0030663 Metformin 129.1
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein