Showing entry for Primary Ciliary Dyskinesia


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD023400
Disease NamePrimary Ciliary Dyskinesia
Disease CUI IdC4551720
MeSH Codes C16   C08   C09  
Disease Class NameCongenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:630   DOID:225  
Disease Ontology Class Namegenetic disease; syndrome
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O76082 BXGT005175 Solute carrier family 22 member 5 6584 reviewed Transporter
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01909 BXGT005815 HLA class II histocompatibility antigen, DQ alpha 1 chain 3117 reviewed Immune response
P01911 BXGT005816 HLA class II histocompatibility antigen, DRB1-15 beta chain 3123 reviewed Immune response
P02741 BXGT005936 C-reactive protein 1401 reviewed
P04070 BXGT006143 Vitamin K-dependent protein C 5624 reviewed Enzyme
P04150 BXGT006154 Glucocorticoid receptor 2908 reviewed Nuclear receptor
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 2064 reviewed Kinase
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05362 BXGT006350 Intercellular adhesion molecule 1 3383 reviewed
P06730 BXGT006487 Eukaryotic translation initiation factor 4E 1977 reviewed Nucleic acid binding
P07202 BXGT006565 Thyroid peroxidase 7173 reviewed Enzyme
P07437 BXGT006624 Tubulin beta chain 203068 reviewed Cellular structure
P07550 BXGT006636 Beta-2 adrenergic receptor 154 reviewed G-protein coupled receptor
P07900 BXGT006696 Heat shock protein HSP 90-alpha 3320 reviewed Chaperone
P08575 BXGT006793 Receptor-type tyrosine-protein phosphatase C 5788 reviewed Enzyme
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10599 BXGT007583 Thioredoxin 7295 reviewed
P11021 BXGT007644 Endoplasmic reticulum chaperone BiP 3309 reviewed
P11226 BXGT007675 Mannose-binding protein C 4153 reviewed Receptor
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P13569 BXGT007923 Cystic fibrosis transmembrane conductance regulator 1080 reviewed Ion channel
P14678 BXGT008038 Small nuclear ribonucleoprotein-associated proteins B and B' 6628 reviewed Nucleic acid binding
P16220 BXGT008206 Cyclic AMP-responsive element-binding protein 1 1385 reviewed
P17516 BXGT008313 Aldo-keto reductase family 1 member C4 1109 reviewed Enzyme
P18827 BXGT008427 Syndecan-1 6382 reviewed Extracellular structure
P21579 BXGT008665 Synaptotagmin-1 6857 reviewed Transporter
P21589 BXGT008669 5'-nucleotidase 4907 reviewed Enzyme
P21730 BXGT008687 C5a anaphylatoxin chemotactic receptor 1 728 reviewed G-protein coupled receptor
P25025 BXGT009006 C-X-C chemokine receptor type 2 3579 reviewed G-protein coupled receptor
P25942 BXGT009079 Tumor necrosis factor receptor superfamily member 5 958 reviewed
P30085 BXGT009399 UMP-CMP kinase 51727 reviewed Kinase
P34932 BXGT009772 Heat shock 70 kDa protein 4 3308 reviewed
P35219 BXGT009797 Carbonic anhydrase-related protein 767 reviewed
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P49913 BXGT010761 Cathelicidin antimicrobial peptide 820 reviewed
P83916 BXGT012025 Chromobox protein homolog 1 10951 reviewed Epigenetic regulator
Q04206 BXGT012754 Transcription factor p65 5970 reviewed Transcription factor
Q13705 BXGT013393 Activin receptor type-2B 93 reviewed Kinase
Q15063 BXGT013531 Periostin 10631 reviewed Signaling
Q16878 BXGT013687 Cysteine dioxygenase type 1 1036 reviewed
Q4KMG0 BXGT014850 Cell adhesion molecule-related/down-regulated by oncogenes 50937 reviewed
Q5VWK5 BXGT015891 Interleukin-23 receptor 149233 reviewed Signaling
Q8WXI4 BXGT019013 Acyl-coenzyme A thioesterase 11 26027 reviewed Enzyme
Q92793 BXGT019374 CREB-binding protein 1387 reviewed
Q92834 BXGT019381 X-linked retinitis pigmentosa GTPase regulator 6103 reviewed
Q9BW19 BXGT020148 Kinesin-like protein KIFC1 3833 reviewed Cellular structure
Q9H015 BXGT020432 Solute carrier family 22 member 4 6583 reviewed Transporter
Q9H4A3 BXGT020473 Serine/threonine-protein kinase WNK1 65125 reviewed Kinase
Q9HC29 BXGT020526 Nucleotide-binding oligomerization domain-containing protein 2 64127 reviewed Enzyme
Q9NRP7 BXGT021192 Serine/threonine-protein kinase 36 27148 reviewed Kinase
Q9NRR6 BXGT021193 Phosphatidylinositol polyphosphate 5-phosphatase type IV 56623 reviewed
Q9UGP5 BXGT021689 DNA polymerase lambda 27343 reviewed Enzyme
Q9UM47 BXGT021772 Neurogenic locus notch homolog protein 3 4854 reviewed
Q16134 BXGT022664 Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial 2110 reviewed Enzyme
Q9BQQ3 BXGT024065 Golgi reassembly-stacking protein 1 64689 reviewed
Q9P121 BXGT025711 Neurotrimin 50863 reviewed
P11836 BXGT025994 B-lymphocyte antigen CD20 931 reviewed Receptor
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease