protein

Showing entry for C-type lectin domain family 10 member A

General Target Information
BXGT Id	BXGT025263
Protein Name	C-type lectin domain family 10 member A
Uniport Id	Q8IUN9
Gene	CLEC10A
Gene Id	10462
Domain	Lectin_C
Pfam	PF00059
Organism	Homo sapiens (Human)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0002250	adaptive immune response
Biological Process	GO:0006897	endocytosis
Biological Process	GO:0045087	innate immune response
Biological Process	GO:0002223	stimulatory C-type lectin receptor signaling pathway
molecular function	GO:0030246	carbohydrate binding
cellular component	GO:0016021	integral component of membrane
cellular component	GO:0005886	plasma membrane

Reactome

Pathway Id	Pathway Name
R-HSA-168249	Innate Immune System
R-HSA-168256	Immune System
R-HSA-5621480	Dectin-2 family
R-HSA-5621481	C-type lectin receptors (CLRs)

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class
C0002736	BXGD000127	Amyotrophic Lateral Sclerosis	Nutritional and Metabolic Diseases; Nervous System Diseases
C0003873	BXGD000236	Rheumatoid Arthritis	Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004096	BXGD000252	Asthma	Respiratory Tract Diseases; Immune System Diseases
C0005586	BXGD000315	Bipolar Disorder	Mental Disorders
C0006142	BXGD000374	Malignant neoplasm of breast	Neoplasms; Skin and Connective Tissue Diseases
C0006826	BXGD000408	Malignant Neoplasms	Neoplasms
C0007137	BXGD000445	Squamous cell carcinoma	Neoplasms
C0007570	BXGD000467	Celiac Disease	Digestive System Diseases; Nutritional and Metabolic Diseases
C0007847	BXGD000492	Malignant tumor of cervix	Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0008373	BXGD000536	Cholesteatoma	Skin and Connective Tissue Diseases
C0009324	BXGD000597	Ulcerative Colitis	Digestive System Diseases
C0010346	BXGD000664	Crohn Disease	Digestive System Diseases
C0011603	BXGD000734	Dermatitis	Skin and Connective Tissue Diseases
C0011615	BXGD000738	Dermatitis, Atopic	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Immune System Diseases
C0013595	BXGD000858	Eczema	Skin and Connective Tissue Diseases
C0014457	BXGD000915	Eosinophilia	Hemic and Lymphatic Diseases
C0017741	BXGD001149	Glucose tolerance test
C0019623	BXGD001341	Malignant histiocytosis	Neoplasms; Hemic and Lymphatic Diseases
C0019693	BXGD001346	HIV Infections	Infections; Immune System Diseases
C0021400	BXGD001504	Influenza	Infections; Respiratory Tract Diseases
C0024299	BXGD001758	Lymphoma	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0025202	BXGD001832	melanoma	Neoplasms
C0027627	BXGD002006	Neoplasm Metastasis	Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651	BXGD002009	Neoplasms	Neoplasms
C0036341	BXGD002600	Schizophrenia	Mental Disorders
C0042769	BXGD002999	Virus Diseases	Infections
C0079731	BXGD003087	B-Cell Lymphomas	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0079774	BXGD003101	Peripheral T-Cell Lymphoma	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0085084	BXGD003121	Motor Neuron Disease	Nervous System Diseases
C0086181	BXGD003267	Intravenous Drug Abuse	Chemically-Induced Disorders; Mental Disorders
C0151744	BXGD003469	Myocardial Ischemia	Cardiovascular Diseases
C0152013	BXGD003516	Adenocarcinoma of lung (disorder)	Neoplasms
C0152230	BXGD003564	Cholinergic urticaria	Skin and Connective Tissue Diseases; Immune System Diseases
C0178874	BXGD004037	Tumor Progression	Pathological Conditions, Signs and Symptoms
C0205851	BXGD004132	Germ cell tumor	Neoplasms
C0206623	BXGD004189	Adenosquamous carcinoma	Neoplasms
C0206664	BXGD004226	Teratocarcinoma	Neoplasms
C0220620	BXGD004299	Gastrointestinal Carcinoid Tumor	Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0242379	BXGD005157	Malignant neoplasm of lung	Neoplasms; Respiratory Tract Diseases
C0279650	BXGD006673	Childhood Acute Megakaryoblastic Leukemia	Neoplasms
C0282687	BXGD006826	Hemorrhagic Fever, Ebola	Infections
C0302592	BXGD006851	Cervix carcinoma	Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0376358	BXGD007992	Malignant neoplasm of prostate	Neoplasms; Male Urogenital Diseases
C0410207	BXGD008419	Tubular Aggregate Myopathy	Musculoskeletal Diseases; Nervous System Diseases
C0456889	BXGD008881	Enteropathy-Associated T-Cell Lymphoma	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0524851	BXGD009246	Neurodegenerative Disorders	Nervous System Diseases
C0600139	BXGD009695	Prostate carcinoma	Neoplasms; Male Urogenital Diseases
C0678222	BXGD009749	Breast Carcinoma	Neoplasms; Skin and Connective Tissue Diseases
C0686619	BXGD009835	Secondary malignant neoplasm of lymph node	Pathological Conditions, Signs and Symptoms; Neoplasms
C0919267	BXGD011426	ovarian neoplasm	Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1140680	BXGD011718	Malignant neoplasm of ovary	Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1306459	BXGD012361	Primary malignant neoplasm	Neoplasms
C1306759	BXGD012374	Eosinophilic disorder	Hemic and Lymphatic Diseases
C1332206	BXGD012504	Adult Lymphoma	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332979	BXGD012571	Childhood Lymphoma	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1444844	BXGD013079	Juvenile idiopathic arthritis, enthesitis related arthritis	Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C1834582	BXGD013982	MYELOPROLIFERATIVE SYNDROME, TRANSIENT	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Hemic and Lymphatic Diseases
C2239176	BXGD016965	Liver carcinoma	Digestive System Diseases; Neoplasms
C2363741	BXGD017100	HIV-1 infection
C2985280	BXGD018223	Blood Protein Measurement
C4048328	BXGD021903	cervical cancer	Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C4285693	BXGD022446	HIV-associated neurocognitive disorder	Infections; Immune System Diseases
C4721452	BXGD023743	Intestinal T-Cell Lymphoma	Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C4721610	BXGD023760	Carcinoma, Ovarian Epithelial	Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases

Target protein-related compounds

Compounds

BXGC Id	Compound Name	Strcuture	Molecular Weight
BXGC0002586	Calcium		40.08
BXGC0003705	Chloride		35.45
BXGC0049447	acetate		59.01

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}