Showing entry for Peripheral T-Cell Lymphoma


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD003101
Disease NamePeripheral T-Cell Lymphoma
Disease CUI IdC0079774
MeSH Codes C04   C20   C15  
Disease Class NameNeoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:7   DOID:14566  
Disease Ontology Class Namedisease of anatomical entity; disease of cellular proliferation
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O14746 BXGT004091 Telomerase reverse transcriptase 7015 reviewed Enzyme
O14757 BXGT004092 Serine/threonine-protein kinase Chk1 1111 reviewed Kinase
O75874 BXGT005157 Isocitrate dehydrogenase [NADP] cytoplasmic 3417 reviewed
O94804 BXGT005334 Serine/threonine-protein kinase 10 6793 reviewed Kinase
P00491 BXGT005555 Purine nucleoside phosphorylase 4860 reviewed Enzyme
P00739 BXGT005633 Haptoglobin-related protein 3250 reviewed Enzyme
P01106 BXGT005730 Myc proto-oncogene protein 4609 reviewed Transcription factor
P01111 BXGT005731 GTPase NRas 4893 reviewed Enzyme modulator
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01579 BXGT005770 Interferon gamma 3458 reviewed
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05771 BXGT006384 Protein kinase C beta type 5579 reviewed Kinase
P06241 BXGT006429 Tyrosine-protein kinase Fyn 2534 reviewed Kinase
P08473 BXGT006773 Neprilysin 4311 reviewed Enzyme
P08684 BXGT006812 Cytochrome P450 3A4 1576 reviewed Enzyme
P09382 BXGT006882 Galectin-1 3956 reviewed Signaling
P10144 BXGT007541 Granzyme B 3002 reviewed Enzyme
P10276 BXGT007553 Retinoic acid receptor alpha 5914 reviewed Nuclear receptor
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10646 BXGT007598 Tissue factor pathway inhibitor 7035 reviewed Enzyme modulator
P10747 BXGT007609 T-cell-specific surface glycoprotein CD28 940 reviewed
P11309 BXGT007685 Serine/threonine-protein kinase pim-1 5292 reviewed Kinase
P11912 BXGT007758 B-cell antigen receptor complex-associated protein alpha chain 973 reviewed Receptor
P14784 BXGT008054 Interleukin-2 receptor subunit beta 3560 reviewed Receptor
P15498 BXGT008133 Proto-oncogene vav 7409 reviewed
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P15813 BXGT008158 Antigen-presenting glycoprotein CD1d 912 reviewed
P16070 BXGT008186 CD44 antigen 960 reviewed
P16234 BXGT008209 Platelet-derived growth factor receptor alpha 5156 reviewed Kinase
P16591 BXGT008246 Tyrosine-protein kinase Fer 2241 reviewed Kinase
P17706 BXGT008330 Tyrosine-protein phosphatase non-receptor type 2 5771 reviewed
P18146 BXGT008384 Early growth response protein 1 1958 reviewed Nucleic acid binding
P19113 BXGT008458 Histidine decarboxylase 3067 reviewed
P19838 BXGT008526 Nuclear factor NF-kappa-B p105 subunit 4790 reviewed Transcription factor
P20248 BXGT008554 Cyclin-A2 890 reviewed Enzyme modulator
P22607 BXGT008784 Fibroblast growth factor receptor 3 2261 reviewed Kinase
P24385 BXGT008965 G1/S-specific cyclin-D1 595 reviewed Enzyme modulator
P25942 BXGT009079 Tumor necrosis factor receptor superfamily member 5 958 reviewed
P28072 BXGT009231 Proteasome subunit beta type-6 5694 reviewed
P28908 BXGT009302 Tumor necrosis factor receptor superfamily member 8 943 reviewed
P29350 BXGT009335 Tyrosine-protein phosphatase non-receptor type 6 5777 reviewed
P29475 BXGT009353 Nitric oxide synthase, brain 4842 reviewed
P31151 BXGT009510 Protein S100-A7 6278 reviewed Calcium-binding protein
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P31785 BXGT009577 Cytokine receptor common subunit gamma 3561 reviewed Signaling
P32302 BXGT009619 C-X-C chemokine receptor type 5 643 reviewed G-protein coupled receptor
P35228 BXGT009800 Nitric oxide synthase, inducible 4843 reviewed
P35610 BXGT009855 Sterol O-acyltransferase 1 6646 reviewed Enzyme
P37023 BXGT009953 Serine/threonine-protein kinase receptor R3 94 reviewed Kinase
P39060 BXGT010088 Collagen alpha-1(XVIII) chain 80781 reviewed
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P41182 BXGT010231 B-cell lymphoma 6 protein 604 reviewed
P41212 BXGT010235 Transcription factor ETV6 2120 reviewed Transcription factor
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P43403 BXGT010385 Tyrosine-protein kinase ZAP-70 7535 reviewed Kinase
P43405 BXGT010386 Tyrosine-protein kinase SYK 6850 reviewed Kinase
P46527 BXGT010525 Cyclin-dependent kinase inhibitor 1B 1027 reviewed
P46531 BXGT010526 Neurogenic locus notch homolog protein 1 4851 reviewed
P48735 BXGT010657 Isocitrate dehydrogenase [NADP], mitochondrial 3418 reviewed
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P50591 BXGT010814 Tumor necrosis factor ligand superfamily member 10 8743 reviewed Signaling
P50613 BXGT010815 Cyclin-dependent kinase 7 1022 reviewed Kinase
P51679 BXGT010877 C-C chemokine receptor type 4 1233 reviewed G-protein coupled receptor
P51692 BXGT010885 Signal transducer and activator of transcription 5B 6777 reviewed Nucleic acid binding
P52333 BXGT010928 Tyrosine-protein kinase JAK3 3718 reviewed Kinase
P55040 BXGT011099 GTP-binding protein GEM 2669 reviewed
P60568 BXGT011315 Interleukin-2 3558 reviewed
P61586 BXGT011375 Transforming protein RhoA 387 reviewed Enzyme modulator
P61769 BXGT011383 Beta-2-microglobulin 567 reviewed Immune response
Q00534 BXGT012533 Cyclin-dependent kinase 6 1021 reviewed Kinase
Q02363 BXGT012650 DNA-binding protein inhibitor ID-2 3398 reviewed Transcription factor
Q02763 BXGT012667 Angiopoietin-1 receptor 7010 reviewed Kinase
Q02790 BXGT012672 Peptidyl-prolyl cis-trans isomerase FKBP4 2288 reviewed Enzyme
Q07820 BXGT012942 Induced myeloid leukemia cell differentiation protein Mcl-1 4170 reviewed Signaling
Q08881 BXGT013012 Tyrosine-protein kinase ITK/TSK 3702 reviewed Kinase
Q13126 BXGT013313 S-methyl-5'-thioadenosine phosphorylase 4507 reviewed Enzyme
Q13315 BXGT013339 Serine-protein kinase ATM 472 reviewed Kinase
Q13547 BXGT013373 Histone deacetylase 1 3065 reviewed Epigenetic regulator
Q14204 BXGT013456 Cytoplasmic dynein 1 heavy chain 1 1778 reviewed Enzyme
Q14289 BXGT013459 Protein-tyrosine kinase 2-beta 2185 reviewed Kinase
Q14790 BXGT013505 Caspase-8 841 reviewed Enzyme
Q15303 BXGT013557 Receptor tyrosine-protein kinase erbB-4 2066 reviewed Kinase
Q15389 BXGT013564 Angiopoietin-1 284 reviewed Signaling
Q15910 BXGT013612 Histone-lysine N-methyltransferase EZH2 2146 reviewed Epigenetic regulator
Q5TC82 BXGT015851 Roquin-1 149041 reviewed
Q6N021 BXGT016378 Methylcytosine dioxygenase TET2 54790 reviewed
Q8TDQ0 BXGT018810 Hepatitis A virus cellular receptor 2 84868 reviewed
Q92692 BXGT019361 Nectin-2 5819 reviewed
Q92769 BXGT019370 Histone deacetylase 2 3066 reviewed Epigenetic regulator
Q99623 BXGT019941 Prohibitin-2 11331 reviewed
Q99653 BXGT019945 Calcineurin B homologous protein 1 11261 reviewed
Q9NR12 BXGT021174 PDZ and LIM domain protein 7 9260 reviewed Cellular structure
Q9NRW4 BXGT021196 Dual specificity protein phosphatase 22 56940 reviewed
Q9NZQ7 BXGT021281 Programmed cell death 1 ligand 1 29126 reviewed Receptor
Q9UBT6 BXGT021664 DNA polymerase kappa 51426 reviewed
Q9UJU2 BXGT021730 Lymphoid enhancer-binding factor 1 51176 reviewed
Q9UKV0 BXGT021750 Histone deacetylase 9 9734 reviewed Epigenetic regulator
Q9UM73 BXGT021773 ALK tyrosine kinase receptor 238 reviewed Kinase
Q9Y6K1 BXGT022331 DNA (cytosine-5)-methyltransferase 3A 1788 reviewed
P31358 BXGT025061 CAMPATH-1 antigen 1043 reviewed
Q8IUN9 BXGT025263 C-type lectin domain family 10 member A 10462 reviewed Receptor
Q9H1K1 BXGT025766 Iron-sulfur cluster assembly enzyme ISCU, mitochondrial 23479 reviewed
P11836 BXGT025994 B-lymphocyte antigen CD20 931 reviewed Receptor
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease