acompound

Showing entry for Liriodenine

General Compound Information
BXGC Id	BXGC0000994
Compound Name	Liriodenine
Structure
Formula	C17H9NO3
InchiKey	MUMCCPUVOAUBAN-UHFFFAOYSA-N
SMILES	O=C1C2=C(C=CC=C2)C2=C3C(C=CN=C13)=CC1=C2OCO1
Inchi	InChI=1S/C17H9NO3/c19-16-11-4-2-1-3-10(11)14-13-9(5-6-18-15(13)16)7-12-17(14)21-8-20-12/h1-7H,8H2
IUPAC	3,5-dioxa-11-azapentacyclo[10.7.1.02,?.0?,2?.01?,1?]icosa-1(20),2(6),7,9,11,14(19),15,17-octaen-13-one
Molecular Weight	275.26
Pubchem Id	10144
Chembl Id	CHEMBL37736

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

50202301

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT008936	Sodium-dependent dopamine transporter	reviewed		Slc6a3	-	31200	-	-
reviewed	BXGT013504	Protein tyrosine phosphatase receptor type C-associated protein	reviewed		PTPRCAP	-	182000	-	-
reviewed	BXGT011367	D(2) dopamine receptor	reviewed		Drd2	-	59000	-	-
reviewed	BXGT008440	D(1A) dopamine receptor	reviewed		Drd1	-	75000	-	-
reviewed	BXGT008936	Sodium-dependent dopamine transporter	reviewed		Slc6a3	-	31000	-	-
reviewed	BXGT004559	Acetylcholinesterase	reviewed		ache	-	>150000	-	-

CHEMBL

CHEMBL37736

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
O42275	BXGT004559	Acetylcholinesterase	reviewed	-	ache	IC50	'>'	150000	nM
P18901	BXGT008440	D(1A) dopamine receptor	reviewed	-	Drd1	IC50	'='	75000	nM
P23977	BXGT008936	Sodium-dependent dopamine transporter	reviewed	-	Slc6a3	IC50	'='	31000	nM
P23977	BXGT008936	Sodium-dependent dopamine transporter	reviewed	-	Slc6a3	IC50	'='	31200	nM
P61169	BXGT011367	D(2) dopamine receptor	reviewed	-	Drd2	IC50	'='	59000	nM
Q14761	BXGT013504	Protein tyrosine phosphatase receptor type C-associated protein	reviewed	-	PTPRCAP	IC50	'='	182000	nM
P00591	BXGT005592	Pancreatic triacylglycerol lipase	reviewed	-	PNLIP	Inhibition	-	-	-
P22002	BXGT008717	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed	-	Cacna1c	IC50	'='	2500	nM
P32297	BXGT009616	Neuronal acetylcholine receptor subunit alpha-3	reviewed	Ion channel	CHRNA3	Inhibition	'='	19	%
P30926	BXGT009482	Neuronal acetylcholine receptor subunit beta-4	reviewed	Ion channel	CHRNB4	Inhibition	'='	19	%
P43681	BXGT010407	Neuronal acetylcholine receptor subunit alpha-4	reviewed	Ion channel	CHRNA4	Inhibition	'='	13	%
P17787	BXGT008341	Neuronal acetylcholine receptor subunit beta-2	reviewed	Ion channel	CHRNB2	Inhibition	'='	13	%

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00014	Custard apple	Annona reticulata	Fruits
BXGF00227	Welsh onion	Allium fistulosum	Herbs and Spices
BXGF00301	Cherimoya	Annona cherimola	Fruits
BXGF00369	Sacred lotus	Nelumbo nucifera	Vegetables
BXGF00397	Colorado pinyon	Pinus edulis	Nuts
BXGF00446	Sugar apple	Annona squamosa	Fruits
BXGF00459	Wax gourd	Benincasa hispida	Gourds
BXGF00863	Pyrus bourgaeana	Pyrus bourgaeana	Human Edible Plant
BXGF00891	Artabotrys uncinatus	Artabotrys uncinatus	Others
BXGF00950	Aconitum vilmorini	Aconitum vilmorini	Others
BXGF01020	Baccharis truncata	Baccharis truncata	Others
BXGF01060	Baccharis grandicapitulata	Baccharis grandicapitulata	Others
BXGF01079	Renealmia alpinia	Renealmia alpinia	Human Edible Plant
BXGF01101	Ononis viscosa	Ononis viscosa	Others
BXGF01192	Cuphea hyssopifolia	Cuphea hyssopifolia	Human Edible Plant
BXGF01207	Morella pensylvanica	Morella pensylvanica	Others
BXGF01237	Magnolia obovata	Magnolia obovata	Medicinal Plant
BXGF01276	Delphinium giraldii	Delphinium giraldii	Medicinal Plant
BXGF01337	Stellaria media	Stellaria media	Medicinal Plant
BXGF01346	Aquilaria agallochum	Aquilaria agallochum	Medicinal Plant
BXGF01394	Holarrhena floribunda	Holarrhena floribunda	Medicinal Plant
BXGF01461	Liriodendron tulipifera	Liriodendron tulipifera	Medicinal Plant
BXGF01493	Curcuma aeruginosa	Curcuma aeruginosa	Medicinal Plant
BXGF01565	Farfugium japonicum	Farfugium japonicum	Medicinal Plant
BXGF01600	Sedum sarmentosum	Sedum sarmentosum	Medicinal Plant
BXGF01603	Piper brachystachyum	Piper brachystachyum	Medicinal Plant
BXGF01628	Salvia broussonetii	Salvia broussonetii	Others
BXGF01656	Eria rigida	Eria rigida	Others
BXGF01688	Tephroseris kirilowii	Tephroseris kirilowii	Medicinal Plant
BXGF01691	Gynoxys verrucosa	Gynoxys verrucosa	Others
BXGF01843	Triunia erythrocarpa	Triunia erythrocarpa	Others
BXGF01967	Senecio congestus	Senecio congestus	Medicinal Plant
BXGF01984	Chloranthus fortunei	Chloranthus fortunei	Others
BXGF02007	Sandoricum koetjape	Sandoricum koetjape	Medicinal Plant
BXGF02033	Suaeda maritima	Suaeda maritima	Medicinal Plant
BXGF02058	Pedicularis rex	Pedicularis rex	Others
BXGF02124	Papaver pseudocanescens	Papaver pseudocanescens	Others
BXGF02137	Goniothalamus amuyon	Goniothalamus amuyon	Medicinal Plant
BXGF02237	Citrus wilsonii	Citrus wilsonii	Medicinal Plant
BXGF02242	Sideritis dasygnaphala	Sideritis dasygnaphala	Others
BXGF02265	Xylopia aethiopica	Xylopia aethiopica	Medicinal Plant
BXGF02346	Piper sylvaticum	Piper sylvaticum	Medicinal Plant
BXGF02382	Gutierrezia dracunculoides	Gutierrezia dracunculoides	Others
BXGF02409	Euphorbia palustris	Euphorbia palustris	Medicinal Plant
BXGF02423	Psidium acutangulum	Psidium acutangulum	Human Edible Plant
BXGF02440	Beesia calthifolia	Beesia calthifolia	Others
BXGF02451	Sorbus torminalis	Sorbus torminalis	Medicinal Plant
BXGF02483	Bursera kerberi	Bursera kerberi	Others
BXGF02509	Xanthium sibiricum	Xanthium sibiricum	Medicinal Plant
BXGF02514	Helenium integrifolium	Helenium integrifolium	Others
BXGF02543	Rhododendron mucronulatum	Rhododendron mucronulatum	Medicinal Plant
BXGF02570	Euonymus fortunei	Euonymus fortunei	Medicinal Plant
BXGF02613	Phlomis crinita	Phlomis crinita	Medicinal Plant
BXGF02661	Sphaerophysa salsula	Sphaerophysa salsula	Others
BXGF02665	Crotalaria stolzii	Crotalaria stolzii	Others
BXGF02682	Selinum libanotis	Selinum libanotis	Others
BXGF02718	Melampodium leucanthum	Melampodium leucanthum	Others
BXGF02734	Clerodendrum trichotomum	Clerodendrum trichotomum	Medicinal Plant
BXGF02750	Juniperus scopulorum	Juniperus scopulorum	Medicinal Plant
BXGF02785	Clinacanthus nutans	Clinacanthus nutans	Medicinal Plant
BXGF02827	Alstonia angustiloba	Alstonia angustiloba	Others
BXGF02840	Lasianthaea podocephala	Lasianthaea podocephala	Others
BXGF02855	Eucalyptus albens	Eucalyptus albens	Others
BXGF02881	Epimedium grandiflorum	Epimedium grandiflorum	Medicinal Plant
BXGF02908	Pellacalyx axillaris	Pellacalyx axillaris	Others
BXGF02914	Michelia alba	Michelia alba	Medicinal Plant
BXGF02922	Stemona tuberosa	Stemona tuberosa	Human Edible Plant
BXGF02930	Euphorbia characias subsp. wulfenii	Euphorbia characias subsp. wulfenii	Medicinal Plant
BXGF02950	Boschniakia rossica	Boschniakia rossica	Medicinal Plant
BXGF02968	Doronicum grandiflorum	Doronicum grandiflorum	Others
BXGF03058	Gymnacranthera paniculata	Gymnacranthera paniculata	Others
BXGF03173	Oxytropis lanata	Oxytropis lanata	Others
BXGF03257	Anagallis monelli	Anagallis monelli	Medicinal Plant
BXGF03259	Populus balsamifera	Populus balsamifera	Medicinal Plant
BXGF03299	Helichrysum fulvum	Helichrysum fulvum	Others
BXGF03315	Magnolia coco	Magnolia coco	Others
BXGF03331	Strychnos gossweileri	Strychnos gossweileri	Others
BXGF03417	Leibnitzia anandria	Leibnitzia anandria	Medicinal Plant
BXGF03475	Lithocarpus haipinii	Lithocarpus haipinii	Others
BXGF03531	Avena fatua	Avena fatua	Medicinal Plant
BXGF03660	Microcos paniculata	Microcos paniculata	Medicinal Plant
BXGF03817	Coffea liberica var. dewevrei	Coffea liberica var. dewevrei	Medicinal Plant
BXGF03957	Centaurea benedicta	Centaurea benedicta	Medicinal Plant
BXGF04011	Botrychium ternatum	Botrychium ternatum	Medicinal Plant
BXGF04064	Rumex japonicus	Rumex japonicus	Medicinal Plant
BXGF04069	Posidonia oceanica	Posidonia oceanica	Others
BXGF04381	Chuquiraga erinacea	Chuquiraga erinacea	Others
BXGF04500	Eliokarmos thyrsoides	Eliokarmos thyrsoides	Others
BXGF04902	Lupinus cosentinii	Lupinus cosentinii	Others
BXGF04912	Corydalis rhizoma	Corydalis rhizoma	Others
BXGF05099	Alpinia flabellata	Alpinia flabellata	Medicinal Plant
BXGF05249	Fouquieria diguetii	Fouquieria diguetii	Others
BXGF05318	Hedysarum gmelini	Hedysarum gmelini	Others
BXGF05465	Euploca racemosa	Euploca racemosa	Others
BXGF05626	Annona glabra	Annona glabra	Medicinal Plant
BXGF05701	Euphorbia pithyusa	Euphorbia pithyusa	Others
BXGF05762	Ardisia hortorum	Ardisia hortorum	Medicinal Plant
BXGF05915	Fritillaria hupehensis	Fritillaria hupehensis	Medicinal Plant
BXGF06054	Angelica japonica	Angelica japonica	Medicinal Plant
BXGF06158	Lathyrus latifolius	Lathyrus latifolius	Medicinal Plant
BXGF06244	Pterocarpus erinaceus	Pterocarpus erinaceus	Medicinal Plant
BXGF06268	Zanthoxylum nitidum	Zanthoxylum nitidum	Medicinal Plant
BXGF06271	Artemisia pectinata	Artemisia pectinata	Others
BXGF06283	Mortonia palmeri	Mortonia palmeri	Others
BXGF06307	Zephyranthes flava	Zephyranthes flava	Others

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}