Showing entry for D(1A) dopamine receptor


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT008440
Protein NameD(1A) dopamine receptor
Uniport IdP18901
GeneDrd1
Gene Id
Domain7tm_1
Pfam PF00001  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007190 activation of adenylate cyclase activity
Biological Process GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway
Biological Process GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
Biological Process GO:0007628 adult walking behavior
Biological Process GO:0008306 associative learning
Biological Process GO:0014002 astrocyte development
Biological Process GO:0001662 behavioral fear response
Biological Process GO:0048148 behavioral response to cocaine
Biological Process GO:0019722 calcium-mediated signaling
Biological Process GO:0071870 cellular response to catecholamine stimulus
Biological Process GO:1903351 cellular response to dopamine
Biological Process GO:0071456 cellular response to hypoxia
Biological Process GO:0032869 cellular response to insulin stimulus
Biological Process GO:0021853 cerebral cortex GABAergic interneuron migration
Biological Process GO:0007268 chemical synaptic transmission
Biological Process GO:0001661 conditioned taste aversion
Biological Process GO:0021542 dentate gyrus development
Biological Process GO:0007212 dopamine receptor signaling pathway
Biological Process GO:0015872 dopamine transport
Biological Process GO:0042755 eating behavior
Biological Process GO:0007631 feeding behavior
Biological Process GO:0046323 glucose import
Biological Process GO:0007186 G protein-coupled receptor signaling pathway
Biological Process GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
Biological Process GO:0007625 grooming behavior
Biological Process GO:0046959 habituation
Biological Process GO:0021766 hippocampus development
Biological Process GO:0043987 histone H3-S10 phosphorylation
Biological Process GO:0006886 intracellular protein transport
Biological Process GO:0007612 learning
Biological Process GO:0007626 locomotory behavior
Biological Process GO:0060292 long-term synaptic depression
Biological Process GO:0060291 long-term synaptic potentiation
Biological Process GO:0042711 maternal behavior
Biological Process GO:0007617 mating behavior
Biological Process GO:0007613 memory
Biological Process GO:0099010 modification of postsynaptic structure
Biological Process GO:0006936 muscle contraction
Biological Process GO:0060548 negative regulation of cell death
Biological Process GO:0030336 negative regulation of cell migration
Biological Process GO:0042321 negative regulation of circadian sleep/wake cycle, sleep
Biological Process GO:0006469 negative regulation of protein kinase activity
Biological Process GO:0019228 neuronal action potential
Biological Process GO:0035106 operant conditioning
Biological Process GO:0021769 orbitofrontal cortex development
Biological Process GO:0030432 peristalsis
Biological Process GO:0060158 phospholipase C-activating dopamine receptor signaling pathway
Biological Process GO:0030335 positive regulation of cell migration
Biological Process GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway
Biological Process GO:2000253 positive regulation of feeding behavior
Biological Process GO:0010628 positive regulation of gene expression
Biological Process GO:1900273 positive regulation of long-term synaptic potentiation
Biological Process GO:0045838 positive regulation of membrane potential
Biological Process GO:0001934 positive regulation of protein phosphorylation
Biological Process GO:0051281 positive regulation of release of sequestered calcium ion into cytosol
Biological Process GO:0051968 positive regulation of synaptic transmission, glutamatergic
Biological Process GO:0099170 postsynaptic modulation of chemical synaptic transmission
Biological Process GO:0006606 protein import into nucleus
Biological Process GO:0042053 regulation of dopamine metabolic process
Biological Process GO:0043269 regulation of ion transport
Biological Process GO:0048169 regulation of long-term neuronal synaptic plasticity
Biological Process GO:0001932 regulation of protein phosphorylation
Biological Process GO:2000300 regulation of synaptic vesicle exocytosis
Biological Process GO:0019229 regulation of vasoconstriction
Biological Process GO:0014823 response to activity
Biological Process GO:0043200 response to amino acid
Biological Process GO:0001975 response to amphetamine
Biological Process GO:0042220 response to cocaine
Biological Process GO:0042493 response to drug
Biological Process GO:0032355 response to estradiol
Biological Process GO:0045471 response to ethanol
Biological Process GO:0032094 response to food
Biological Process GO:0043278 response to morphine
Biological Process GO:0035094 response to nicotine
Biological Process GO:0014070 response to organic cyclic compound
Biological Process GO:0010243 response to organonitrogen compound
Biological Process GO:0032526 response to retinoic acid
Biological Process GO:0048545 response to steroid hormone
Biological Process GO:0046960 sensitization
Biological Process GO:0035176 social behavior
Biological Process GO:0021756 striatum development
Biological Process GO:0007416 synapse assembly
Biological Process GO:0001963 synaptic transmission, dopaminergic
Biological Process GO:0001659 temperature homeostasis
Biological Process GO:0019226 transmission of nerve impulse
Biological Process GO:0042311 vasodilation
Biological Process GO:0008542 visual learning
molecular function GO:0031701 angiotensin receptor binding
molecular function GO:0051117 ATPase binding
molecular function GO:0031750 D3 dopamine receptor binding
molecular function GO:0035240 dopamine binding
molecular function GO:0004952 dopamine neurotransmitter receptor activity
molecular function GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs
molecular function GO:0008144 drug binding
molecular function GO:0001965 G-protein alpha-subunit binding
molecular function GO:0004930 G protein-coupled receptor activity
molecular function GO:0004993 G protein-coupled serotonin receptor activity
molecular function GO:0030594 neurotransmitter receptor activity
molecular function GO:0044877 protein-containing complex binding
molecular function GO:0019903 protein phosphatase binding
molecular function GO:0005102 signaling receptor binding
cellular component GO:0030424 axon
cellular component GO:0043679 axon terminus
cellular component GO:0005901 caveola
cellular component GO:0060170 ciliary membrane
cellular component GO:0005929 cilium
cellular component GO:0030425 dendrite
cellular component GO:0043198 dendritic shaft
cellular component GO:0043197 dendritic spine
cellular component GO:0044327 dendritic spine head
cellular component GO:0044326 dendritic spine neck
cellular component GO:0012505 endomembrane system
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0005789 endoplasmic reticulum membrane
cellular component GO:0098982 GABA-ergic synapse
cellular component GO:0098978 glutamatergic synapse
cellular component GO:0016021 integral component of membrane
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0099055 integral component of postsynaptic membrane
cellular component GO:0099056 integral component of presynaptic membrane
cellular component GO:0016020 membrane
cellular component GO:0043025 neuronal cell body
cellular component GO:0097730 non-motile cilium
cellular component GO:0005634 nucleus
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000538 (R)-Norepinephrine 169.18
BXGC0000994 Liriodenine 275.26
BXGC0001495 (R)-Roemerine 279.33
BXGC0001538 Atherosperminine 309.4
BXGC0002867 Lappaurin 284.74
BXGC0003005 3-Phenylpyridine 155.2
BXGC0003066 Phenols 199.27
BXGC0003196 Aripiprazole 448.39
BXGC0004665 4-Aminobutyric acid 103.12
BXGC0005867 Serotonin 176.22
BXGC0005871 Dopamine 153.18
BXGC0006162 L-Glutamic acid 147.13
BXGC0013854 Histamine 111.08
BXGC0014063 Norstephalagine 295.12
BXGC0014322 (S)-Bulbocapnine 325.13
BXGC0014634 Homoaromoline 608.29
BXGC0014893 2,3-Dimethoxy-6-Methyl-5,6,6A,7-Tetrahydro-4H-Dibenzo[De,G]Quinolin-1-Ol 311.15
BXGC0018547 N,N-Dimethyl-2-Naphtho[2,1-G][1,3]Benzodioxol-5-Ylethanamine 293.14
BXGC0019520 Anolobine 281.11
BXGC0021893 Norepinephrine 169.07
BXGC0022524 Isopiline 297.14
BXGC0024722 Stepholidine 327.15
BXGC0024748 Anonaine 265.11
BXGC0029807 Anisocoumarin H 314.15
BXGC0031080 Scopolamine 303.15
BXGC0031384 Epinephrine 183.09
BXGC0031861 6-Methyl-5,6,6A,7-Tetrahydro-4H-Dibenzo[De,G]Quinoline 235.14
BXGC0033089 Falcarindiol 260.18
BXGC0033674 Predicentrine 341.16
BXGC0034961 Norboldine 313.13
BXGC0035865 (+)-Pentazocine 285.21
BXGC0035962 Notopterol 354.15
BXGC0041195 Boldine 327.15
BXGC0042455 (+/-)-Nuciferine 295.16
BXGC0042510 Fluoxetine 309.13
BXGC0042574 Ibogaine 310.2
BXGC0046755 Yohimbine 354.19
BXGC0048699 Obaberine 622.3
BXGC0050517 (R)-(+)-Coclaurine 285.14
BXGC0050599 tetrandrine 622.3
BXGC0053872 Glaucine 355.18
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein