acompound

Showing entry for 2-Methoxyphenol

General Compound Information
BXGC Id	BXGC0005668
Compound Name	2-Methoxyphenol
Structure
Formula	C7H8O2
InchiKey	LHGVFZTZFXWLCP-UHFFFAOYSA-N
SMILES	COC1=C(O)C=CC=C1
Inchi	InChI=1S/C7H8O2/c1-9-7-5-3-2-4-6(7)8/h2-5,8H,1H3
IUPAC	2-methoxyphenol
Molecular Weight	124.14
Pubchem Id	460
Chembl Id	CHEMBL13766

Targets of Information Source

DrugBank

DB11359

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
P02768	BXGT005955	Serum albumin	reviewed	Transporter	ALB	approved	-

PDB

JZ3

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
P00720	BXGT005625	Endolysin	reviewed	E	-	-	-	-	-
P00431	BXGT005533	Cytochrome c peroxidase, mitochondrial	reviewed	CCP1	-	-	-	-	-
O94753	BXGT005326	Versatile peroxidase VPL2	reviewed	vpl2	-	-	-	-	-
A0A076MY51	BXGT000069	Cytochrome P450	unreviewed	AMETH_3834	-	-	-	-	-
P0DPQ7	BXGT024215	Aromatic O-demethylase, cytochrome P450 subunit	reviewed	gcoA	-	-	-	7100	-
P0DPQ7	BXGT024215	Aromatic O-demethylase, cytochrome P450 subunit	reviewed	gcoA	-	-	-	-	-
P02185	BXGT005855	Myoglobin	reviewed	MB	-	-	-	-	-

Binding DB

50240369

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT005689	Carbonic anhydrase 1	reviewed		CA1	60230	-	-	-
reviewed	BXGT005690	Carbonic anhydrase 2	reviewed		CA2	2980	-	-	-
reviewed	BXGT008802	Carbonic anhydrase 4	reviewed		CA4	3560	-	-	-
reviewed	BXGT008844	Carbonic anhydrase 6	reviewed		CA6	217000	-	-	-
reviewed	BXGT005689	Carbonic anhydrase 1	reviewed		CA1	60200	-	-	-
reviewed	BXGT005690	Carbonic anhydrase 2	reviewed		CA2	2940	-	-	-

CHEMBL

CHEMBL13766

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P51449	BXGT010846	Nuclear receptor ROR-gamma	reviewed	Nuclear receptor	RORC	Potency	-	149	nM
P16473	BXGT008234	Thyrotropin receptor	reviewed	G-protein coupled receptor	TSHR	Potency	'='	5011	nM
P00811	BXGT005666	Beta-lactamase	reviewed	-	ampC	Potency	'='	5623	nM
P15917	BXGT008169	Lethal factor	reviewed	-	lef	Inhibition	'='	13	%
Q16236	BXGT013624	Nuclear factor erythroid 2-related factor 2	reviewed	Enzyme	NFE2L2	Potency	-	7307	nM
P29477	BXGT009355	Nitric oxide synthase, inducible	reviewed	-	Nos2	Inhibition	'='	13	%
P00915	BXGT005689	Carbonic anhydrase 1	reviewed	-	CA1	Ki	'='	60200	nM
P15917	BXGT008169	Lethal factor	reviewed	-	lef	Potency	'='	1000	nM
P22894	BXGT008815	Neutrophil collagenase	reviewed	Enzyme	MMP8	Inhibition	'='	4	%
P03956	BXGT006120	Interstitial collagenase	reviewed	Enzyme	MMP1	Inhibition	'='	8	%
O42713	BXGT004563	Polyphenol oxidase 2	reviewed	-	PPO2	Inhibition	'='	-20	%
P00918	BXGT005690	Carbonic anhydrase 2	reviewed	-	CA2	Ki	'='	2940	nM
Q96KQ7	BXGT019687	Histone-lysine N-methyltransferase EHMT2	reviewed	Epigenetic regulator	EHMT2	Potency	-	22387	nM
Q96QE3	BXGT019718	ATPase family AAA domain-containing protein 5	reviewed	-	ATAD5	Potency	-	580	nM
P09917	BXGT006941	Arachidonate 5-lipoxygenase	reviewed	Enzyme	ALOX5	Inhibition	'='	60	%
P04637	BXGT006243	Cellular tumor antigen p53	reviewed	Transcription factor	TP53	Potency	'='	12	nM
P14780	BXGT008053	Matrix metalloproteinase-9	reviewed	Enzyme	MMP9	Inhibition	'='	-6	%
Q9R1A7	BXGT021413	Nuclear receptor subfamily 1 group I member 2	reviewed	-	Nr1i2	Potency	-	79432	nM
P08254	BXGT006758	Stromelysin-1	reviewed	Enzyme	MMP3	Inhibition	'='	-4	%
P08253	BXGT006757	72 kDa type IV collagenase	reviewed	Enzyme	MMP2	Inhibition	'='	-5	%
Q13936	BXGT013404	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed	Ion channel	CACNA1C	IC50	-	-	-
P10275	BXGT007552	Androgen receptor	reviewed	Nuclear receptor	AR	Potency	-	12589	nM
O95342	BXGT005373	Bile salt export pump	reviewed	Transporter	ABCB11	IC50	'>'	1000000	nM

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00015	Wild celery	Apium graveolens	Herbs and Spices
BXGF00021	Asparagus	Asparagus officinalis	Vegetables
BXGF00038	Tea	Camellia sinensis	Teas
BXGF00040	Pepper (C. annuum)	Capsicum annuum	Vegetables
BXGF00050	Chinese cinnamon	Cinnamomum aromaticum	Herbs and Spices
BXGF00058	Coffee	Coffea	Coffee and coffee products
BXGF00059	Arabica coffee	Coffea arabica	Coffee and coffee products
BXGF00068	Turmeric	Curcuma longa	Herbs and Spices
BXGF00081	Fig	Ficus carica	Fruits
BXGF00113	Peppermint	Mentha X piperita	Herbs and Spices
BXGF00170	Sesame	Sesamum orientale	Herbs and Spices
BXGF00173	Garden tomato (var.)	Solanum lycopersicum var. lycopersicum	Vegetables
BXGF00205	Corn	Zea mays	Cereals and cereal products
BXGF00380	White mustard	Sinapis alba	Herbs and Spices
BXGF00815	Milk and milk products		Milk and milk products
BXGF00819	Pulses		Pulses
BXGF00829	Green bell pepper	Capsicum annuum	Vegetables
BXGF00830	Yellow bell pepper	Capsicum annuum	Vegetables
BXGF00831	Orange bell pepper	Capsicum annuum	Vegetables
BXGF00832	Red bell pepper	Capsicum annuum	Vegetables
BXGF01140	Angelica gigas	Angelica gigas	Medicinal Plant
BXGF01424	Atractylodes chinensis	Atractylodes chinensis	Medicinal Plant
BXGF02024	Actaea dahurica	Actaea dahurica	Human Edible Plant
BXGF02049	Angelica sinensis	Angelica sinensis	Medicinal Plant
BXGF02143	Actaea cimicifuga	Actaea cimicifuga	Medicinal Plant
BXGF02182	Atractylodes lancea	Atractylodes lancea	Medicinal Plant
BXGF02243	Scopolia parviflora	Scopolia parviflora	Medicinal Plant
BXGF02815	Pinellia ternata	Pinellia ternata	Medicinal Plant
BXGF04402	Actaea simplex	Actaea simplex	Others
BXGF04607	Morus alba	Morus alba	Medicinal Plant
BXGF04712	Prunus mume	Prunus mume	Medicinal Plant
BXGF04820	Panax ginseng	Panax ginseng	0
BXGF04842	Angelica acutiloba	Angelica acutiloba	Medicinal Plant
BXGF04875	Bupleurum chinense	Bupleurum chinense	Medicinal Plant
BXGF05462	Campsis flos	Campsis flos	Others
BXGF06026	Magnolia officinalis rehd et wils	Magnolia officinalis rehd et wils	Others
BXGF06071	Acorus tatarinowii	Acorus tatarinowii	Medicinal Plant
BXGF06161	Epimedium wushanense	Epimedium wushanense	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}