acompound

Showing entry for 2'-Hydroxygenistein

General Compound Information
BXGC Id	BXGC0005945
Compound Name	2'-Hydroxygenistein
Structure
Formula	C15H10O6
InchiKey	GSSOWCUOWLMMRJ-UHFFFAOYSA-N
SMILES	OC1=CC(O)=C(C=C1)C1=COC2=CC(O)=CC(O)=C2C1=O
Inchi	InChI=1S/C15H10O6/c16-7-1-2-9(11(18)3-7)10-6-21-13-5-8(17)4-12(19)14(13)15(10)20/h1-6,16-19H
IUPAC	3-(2,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one
Molecular Weight	286.24
Pubchem Id	5282074
Chembl Id	CHEMBL6665

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

50142192

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT005616	Lysozyme C-1	reviewed		Lyz1	-	9700	-	-
reviewed	BXGT006500	Beta-glucuronidase	reviewed		Gusb	-	5900	-	-

CHEMBL

CHEMBL6665

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P06746	BXGT006496	DNA polymerase beta	reviewed	Enzyme	POLB	Potency	'='	31622	nM
P00697	BXGT005616	Lysozyme C-1	reviewed	-	Lyz1	IC50	'='	9700	nM
Q96QE3	BXGT019718	ATPase family AAA domain-containing protein 5	reviewed	-	ATAD5	Potency	-	29081	nM
P10253	BXGT007550	Lysosomal alpha-glucosidase	reviewed	Enzyme	GAA	Potency	'='	31622	nM
P08659	BXGT006805	Luciferin 4-monooxygenase	reviewed	-		Potency	-	30131	nM
Q9Y253	BXGT022216	DNA polymerase eta	reviewed	-	POLH	Potency	-	79432	nM
P06760	BXGT006500	Beta-glucuronidase	reviewed	-	Gusb	IC50	'='	5900	nM
Q63470	BXGT016073	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	reviewed	-	Dyrk1a	AC50	'='	11325	nM
Q03431	BXGT012714	Parathyroid hormone/parathyroid hormone-related peptide receptor	reviewed	G-protein coupled receptor	PTH1R	Potency	-	56234	nM
P27695	BXGT009199	DNA-(apurinic or apyrimidinic site) lyase	reviewed	-	APEX1	Potency	-	25118	nM
P10636	BXGT007596	Microtubule-associated protein tau	reviewed	-	MAPT	Potency	'='	12589	nM
Q9UNA4	BXGT021785	DNA polymerase iota	reviewed	-	POLI	Potency	-	63095	nM
Q9UBT6	BXGT021664	DNA polymerase kappa	reviewed	-	POLK	Potency	-	89125	nM
P14061	BXGT007979	Estradiol 17-beta-dehydrogenase 1	reviewed	Enzyme	HSD17B1	IC50	'='	1090	nM
P37059	BXGT009957	Estradiol 17-beta-dehydrogenase 2	reviewed	Enzyme	HSD17B2	IC50	'='	2030	nM

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00037	Pigeon pea	Cajanus cajan	Pulses
BXGF00132	Scarlet bean	Phaseolus coccineus	Pulses
BXGF00134	Common bean	Phaseolus vulgaris	Pulses
BXGF00198	Adzuki bean	Vigna angularis	Pulses
BXGF00370	White lupine	Lupinus albus	Pulses
BXGF00819	Pulses		Pulses
BXGF00823	Fruits		Fruits
BXGF00834	Yellow wax bean	Phaseolus vulgaris	Pulses
BXGF00835	Green bean	Phaseolus vulgaris	Pulses
BXGF00865	Hyoscyamus pusillus	Hyoscyamus pusillus	Medicinal Plant
BXGF00903	Crotalaria assamica	Crotalaria assamica	Medicinal Plant
BXGF00957	Allagopappus viscosissimus	Allagopappus viscosissimus	Others
BXGF00980	Parameria laevigata	Parameria laevigata	Medicinal Plant
BXGF01173	Astragalus spinosus	Astragalus spinosus	Others
BXGF01235	Swertia decussata	Swertia decussata	Medicinal Plant
BXGF01269	Peltogyne pubescens	Peltogyne pubescens	Others
BXGF01321	Ranunculus peltatus	Ranunculus peltatus	Others
BXGF01349	Hydrangea serrata	Hydrangea serrata	Medicinal Plant
BXGF01437	Lunularia cruciata	Lunularia cruciata	Others
BXGF01503	Astragalus bicuspis	Astragalus bicuspis	Others
BXGF01761	Styrax agrestis	Styrax agrestis	Others
BXGF01884	Justicia adhatoda	Justicia adhatoda	Medicinal Plant
BXGF02687	Papaver tatricum	Papaver tatricum	Others
BXGF03242	Crotalaria lachnophora	Crotalaria lachnophora	Human Edible Plant
BXGF03731	Rosulabryum capillare	Rosulabryum capillare	Others
BXGF03774	Citrus rugulosa	Citrus rugulosa	Others
BXGF04060	Aglaia australiensis	Aglaia australiensis	Others
BXGF04274	Macadamia ternifolia	Macadamia ternifolia	Medicinal Plant
BXGF05041	Desmodium styracifolium	Desmodium styracifolium	Medicinal Plant
BXGF05050	Diplacus longiflorus	Diplacus longiflorus	Others
BXGF05129	Achillea pseudopectinata	Achillea pseudopectinata	Others
BXGF05291	Teucrium marum	Teucrium marum	Medicinal Plant
BXGF05328	Syzygium nervosum	Syzygium nervosum	Human Edible Plant
BXGF05366	Lepidosperma ustulatum	Lepidosperma ustulatum	Others
BXGF05526	Salvia miltiorrhiza	Salvia miltiorrhiza	Medicinal Plant
BXGF05678	Dunalia solanacea	Dunalia solanacea	Others
BXGF05761	Berberis floribunda	Berberis floribunda	Medicinal Plant
BXGF05810	Pterocarpus indicus	Pterocarpus indicus	Medicinal Plant
BXGF05820	Jamesoniella colorata	Jamesoniella colorata	Medicinal Plant
BXGF05875	Fumaria micrantha	Fumaria micrantha	Others
BXGF05935	Pterodon emarginatus	Pterodon emarginatus	Others
BXGF05948	Berlinia tomentosa	Berlinia tomentosa	Others
BXGF06010	Hibiscus schizopetalus	Hibiscus schizopetalus	Medicinal Plant
BXGF06014	Cymodocea nodosa	Cymodocea nodosa	Others
BXGF06061	Flemingia macrophylla	Flemingia macrophylla	Medicinal Plant
BXGF06077	Bonamia spectabilis	Bonamia spectabilis	Others
BXGF06129	Atuna racemosa	Atuna racemosa	Human Edible Plant
BXGF06180	Astragalus pycnanthus	Astragalus pycnanthus	Others
BXGF06223	Pulsatilla campanella	Pulsatilla campanella	Medicinal Plant
BXGF06266	Crotalaria pallida	Crotalaria pallida	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}