acompound

Showing entry for Naringenin fructoside

General Compound Information
BXGC Id	BXGC0008958
Compound Name	Naringenin fructoside
Structure
Formula	C15H12O5
InchiKey	FTVWIRXFELQLPI-UHFFFAOYSA-N
SMILES	OC1=CC=C(C=C1)C1CC(=O)C2=C(O)C=C(O)C=C2O1
Inchi	InChI=1S/C15H12O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-6,13,16-18H,7H2
IUPAC	5,7-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one
Molecular Weight	272.26
Pubchem Id	932
Chembl Id	CHEMBL32571

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

19461

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT006059	Estrogen receptor	reviewed	Nuclear receptor	ESR1	-	72302	-	-
reviewed	BXGT019366	Estrogen receptor beta	reviewed	Nuclear receptor	ESR2	-	13473	-	-
reviewed	BXGT007717	Aromatase	reviewed	Enzyme	CYP19A1	0.00109662	1000	-	-
reviewed	BXGT005689	Carbonic anhydrase 1	reviewed		CA1	970	-	-	-
reviewed	BXGT005690	Carbonic anhydrase 2	reviewed		CA2	113	-	-	-
reviewed	BXGT014517	Carbonic anhydrase 3	reviewed		CA3	2210	-	-	-
reviewed	BXGT008802	Carbonic anhydrase 4	reviewed		CA4	1120	-	-	-
reviewed	BXGT008844	Carbonic anhydrase 6	reviewed		CA6	1490	-	-	-

CHEMBL

CHEMBL32571

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P08659	BXGT006805	Luciferin 4-monooxygenase	reviewed	-		Potency	-	30131	nM
O75496	BXGT005132	Geminin	reviewed	-	GMNN	Potency	-	2511	nM
P02791	BXGT005965	Ferritin light chain	reviewed	-	FTL	Potency	'='	28183	nM
Q03164	BXGT012700	Histone-lysine N-methyltransferase 2A	reviewed	-	KMT2A	Potency	'='	25118	nM
O00255	BXGT003903	Menin	reviewed	-	MEN1	Potency	'='	25118	nM
P04062	BXGT006140	Lysosomal acid glucosylceramidase	reviewed	-	GBA	Potency	-	22387	nM
P09917	BXGT006941	Arachidonate 5-lipoxygenase	reviewed	Enzyme	ALOX5	Inhibition	'<'	50	%
P04062	BXGT006140	Lysosomal acid glucosylceramidase	reviewed	-	GBA	Potency	-	11220	nM
P08684	BXGT006812	Cytochrome P450 3A4	reviewed	Enzyme	CYP3A4	Potency	'='	12589	nM
P08684	BXGT006812	Cytochrome P450 3A4	reviewed	Enzyme	CYP3A4	Potency	'='	10000	nM
P18054	BXGT008370	Arachidonate 12-lipoxygenase, 12S-type	reviewed	Enzyme	ALOX12	Potency	'='	35481	nM
P27695	BXGT009199	DNA-(apurinic or apyrimidinic site) lyase	reviewed	-	APEX1	Potency	-	199526	nM
Q03164	BXGT012700	Histone-lysine N-methyltransferase 2A	reviewed	-	KMT2A	Potency	'='	39810	nM
O00255	BXGT003903	Menin	reviewed	-	MEN1	Potency	'='	39810	nM
Q9UNA4	BXGT021785	DNA polymerase iota	reviewed	-	POLI	Potency	-	631	nM
P22002	BXGT008717	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed	-	Cacna1c	IC50	'='	100000	nM
P14916	BXGT008066	Urease subunit alpha	reviewed	-	ureA	IC50	'='	328000	nM
P69996	BXGT011656	Urease subunit beta	reviewed	-	ureB	IC50	'='	328000	nM
P51450	BXGT010847	Nuclear receptor ROR-gamma	reviewed	-	Rorc	Potency	'='	15848	nM
P51450	BXGT010847	Nuclear receptor ROR-gamma	reviewed	-	Rorc	Potency	'='	35481	nM
O15648	BXGT004185	ATP-dependent 6-phosphofructokinase	reviewed	-	pfk	Potency	-	756	nM
P22411	BXGT008763	Dipeptidyl peptidase 4	reviewed	-	DPP4	IC50	'='	2500	nM
Q15118	BXGT013540	[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial	reviewed	Kinase	PDK1	Inhibition	'='	4	%
P24941	BXGT009002	Cyclin-dependent kinase 2	reviewed	Kinase	CDK2	Inhibition	'='	14	%
P24864	BXGT009000	G1/S-specific cyclin-E1	reviewed	Enzyme modulator	CCNE1	Inhibition	'='	14	%

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00011	Cashew nut	Anacardium occidentale	Nuts
BXGF00038	Tea	Camellia sinensis	Teas
BXGF00055	Pummelo	Citrus maxima	Fruits
BXGF00057	Sweet orange	Citrus sinensis	Fruits
BXGF00063	Saffron	Crocus sativus	Herbs and Spices
BXGF00082	Fennel	Foeniculum vulgare	Herbs and Spices
BXGF00149	Peach	Prunus persica	Fruits
BXGF00183	Common thyme	Thymus vulgaris	Herbs and Spices
BXGF00186	Fenugreek	Trigonella foenum-graecum	Herbs and Spices
BXGF00206	Ginger	Zingiber officinale	Herbs and Spices
BXGF00522	Narrowleaf cattail	Typha angustifolia	Vegetables
BXGF00871	Citrus unshiu	Citrus unshiu	Medicinal Plant
BXGF01215	Cirsium setosum	Cirsium setosum	Medicinal Plant
BXGF01267	Dendrobium chrysanthum	Dendrobium chrysanthum	Medicinal Plant
BXGF01506	Thymus quinquecostatus	Thymus quinquecostatus	Medicinal Plant
BXGF01721	Humulus lupulus	Humulus lupulus	Medicinal Plant
BXGF01868	Vitex negundo	Vitex negundo	Medicinal Plant
BXGF02167	Scutellaria barbata	Scutellaria barbata	Medicinal Plant
BXGF02362	Prunus serrulata var. spontanea	Prunus serrulata var. spontanea	Medicinal Plant
BXGF02381	Glycyrrhiza inflata	Glycyrrhiza inflata	Medicinal Plant
BXGF02626	Dalbergia odorifera	Dalbergia odorifera	Medicinal Plant
BXGF03078	Chrysanthemum x morifolium	Chrysanthemum x morifolium	Medicinal Plant
BXGF03152	Sophora japonica	Sophora japonica	Medicinal Plant
BXGF03161	Dendrobium chrysotoxum	Dendrobium chrysotoxum	Medicinal Plant
BXGF03189	Rhododendron dauricum	Rhododendron dauricum	Medicinal Plant
BXGF03327	Citrus trifoliata	Citrus trifoliata	Human Edible Plant
BXGF03346	Dendrobium candidum	Dendrobium candidum	Others
BXGF03398	Solanum nigrum	Solanum nigrum	Medicinal Plant
BXGF03632	Dendrobium fimbriatum	Dendrobium fimbriatum	Medicinal Plant
BXGF03721	Lysimachia christinae	Lysimachia christinae	Medicinal Plant
BXGF04053	Smilax china	Smilax china	Medicinal Plant
BXGF04062	Spatholobus suberectus	Spatholobus suberectus	Medicinal Plant
BXGF04080	Persicaria orientalis	Persicaria orientalis	Medicinal Plant
BXGF04200	Euphorbia hirta	Euphorbia hirta	Medicinal Plant
BXGF04600	Typha orientalis	Typha orientalis	Medicinal Plant
BXGF04712	Prunus mume	Prunus mume	Medicinal Plant
BXGF04817	Euonymus alatus	Euonymus alatus	Medicinal Plant
BXGF04872	Glycyrrhiza glabra	Glycyrrhiza glabra	Medicinal Plant
BXGF04881	Fallopia multiflora	Fallopia multiflora	Medicinal Plant
BXGF04928	Citrus grandis	Citrus grandis	Medicinal Plant
BXGF05041	Desmodium styracifolium	Desmodium styracifolium	Medicinal Plant
BXGF05173	Dendrobium nobile	Dendrobium nobile	Medicinal Plant
BXGF05204	Erigeron breviscapus	Erigeron breviscapus	Medicinal Plant
BXGF05277	Prunus davidiana	Prunus davidiana	Medicinal Plant
BXGF05387	Garcinia multiflora	Garcinia multiflora	Medicinal Plant
BXGF05431	Citrus natsudaidai	Citrus natsudaidai	Human Edible Plant
BXGF05631	Turpinia arguta	Turpinia arguta	Others
BXGF05722	Hedysarum polybotrys	Hedysarum polybotrys	Medicinal Plant
BXGF05787	Smilax glabra	Smilax glabra	Medicinal Plant
BXGF05790	Glycyrrhiza uralensis	Glycyrrhiza uralensis	Medicinal Plant
BXGF05819	Citrus aurantium	Citrus aurantium	Medicinal Plant
BXGF06069	Dendrobium loddigesii	Dendrobium loddigesii	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}