Showing entry for Prostratin


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0019625
Compound NameProstratin
Structure
FormulaC22H30O6
InchiKeyBOJKFRKNLSCGHY-HXGSDTCMSA-N
SMILESOCC1=C[C@H]2[C@H]3[C@@](C3(C)C)(OC(=O)C)C[C@H]([C@@]2([C@H]2[C@@](C1)(O)C(=O)C(=C2)C)O)C
InchiInChI=1S/C22H30O6/c1-11-6-16-20(26,18(11)25)9-14(10-23)7-15-17-19(4,5)21(17,28-13(3)24)8-12(2)22(15,16)27/h6-7,12,15-17,23,26-27H,8-10H2,1-5H3/t12-,15+,16-,17-,20-,21+,22-/m1/s1
IUPAC
Molecular Weight390.2
Pubchem Id454217
Chembl IdCHEMBL170518
Targets of Information Source
DrugBank n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
PDB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Binding DB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
CHEMBL CHEMBL170518
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
Q04759 BXGT012781 Protein kinase C theta type reviewed Kinase PRKCQ Ki '=' 190 nM
Q15139 BXGT013546 Serine/threonine-protein kinase D1 reviewed Kinase PRKD1 Ki '=' 190 nM
P24723 BXGT008989 Protein kinase C eta type reviewed Kinase PRKCH Ki '=' 190 nM
Q02156 BXGT012639 Protein kinase C epsilon type reviewed Kinase PRKCE Ki '=' 190 nM
P05771 BXGT006384 Protein kinase C beta type reviewed Kinase PRKCB Ki '=' 190 nM
Q05655 BXGT012832 Protein kinase C delta type reviewed Kinase PRKCD Ki '=' 190 nM
P05129 BXGT006322 Protein kinase C gamma type reviewed Kinase PRKCG Ki '=' 190 nM
P17252 BXGT008294 Protein kinase C alpha type reviewed Kinase PRKCA Ki '=' 190 nM
O94806 BXGT005335 Serine/threonine-protein kinase D3 reviewed Kinase PRKD3 Ki '=' 190 nM
Q04759 BXGT012781 Protein kinase C theta type reviewed Kinase PRKCQ Ki '=' 210 nM
Q15139 BXGT013546 Serine/threonine-protein kinase D1 reviewed Kinase PRKD1 Ki '=' 210 nM
P24723 BXGT008989 Protein kinase C eta type reviewed Kinase PRKCH Ki '=' 210 nM
Q02156 BXGT012639 Protein kinase C epsilon type reviewed Kinase PRKCE Ki '=' 210 nM
P05771 BXGT006384 Protein kinase C beta type reviewed Kinase PRKCB Ki '=' 210 nM
Q05655 BXGT012832 Protein kinase C delta type reviewed Kinase PRKCD Ki '=' 210 nM
P05129 BXGT006322 Protein kinase C gamma type reviewed Kinase PRKCG Ki '=' 210 nM
P17252 BXGT008294 Protein kinase C alpha type reviewed Kinase PRKCA Ki '=' 210 nM
O94806 BXGT005335 Serine/threonine-protein kinase D3 reviewed Kinase PRKD3 Ki '=' 210 nM
P04409 BXGT006208 Protein kinase C alpha type reviewed - PRKCA Ki '=' 4 nM
Q04759 BXGT012781 Protein kinase C theta type reviewed Kinase PRKCQ Activity - - -
Q15139 BXGT013546 Serine/threonine-protein kinase D1 reviewed Kinase PRKD1 Activity - - -
P24723 BXGT008989 Protein kinase C eta type reviewed Kinase PRKCH Activity - - -
Q02156 BXGT012639 Protein kinase C epsilon type reviewed Kinase PRKCE Activity - - -
Q05513 BXGT012820 Protein kinase C zeta type reviewed Kinase PRKCZ Activity - - -
P05771 BXGT006384 Protein kinase C beta type reviewed Kinase PRKCB Activity - - -
Q05655 BXGT012832 Protein kinase C delta type reviewed Kinase PRKCD Activity - - -
P05129 BXGT006322 Protein kinase C gamma type reviewed Kinase PRKCG Activity - - -
P17252 BXGT008294 Protein kinase C alpha type reviewed Kinase PRKCA Activity - - -
P41743 BXGT010270 Protein kinase C iota type reviewed Kinase PRKCI Activity - - -
O94806 BXGT005335 Serine/threonine-protein kinase D3 reviewed Kinase PRKD3 Activity - - -
Q01279 BXGT012581 Epidermal growth factor receptor reviewed - Egfr Effective concentration '=' 220 nM
O42275 BXGT004559 Acetylcholinesterase reviewed - ache Inhibition '=' -10 %
P81908 BXGT011959 Cholinesterase reviewed - BCHE Inhibition '=' 3 %
P17252 BXGT008294 Protein kinase C alpha type reviewed Kinase PRKCA Activity - - -
Q05655 BXGT012832 Protein kinase C delta type reviewed Kinase PRKCD Activity - - -
Q04759 BXGT012781 Protein kinase C theta type reviewed Kinase PRKCQ Activity - - -
Q04759 BXGT012781 Protein kinase C theta type reviewed Kinase PRKCQ EC50 '=' 910 nM
Q15139 BXGT013546 Serine/threonine-protein kinase D1 reviewed Kinase PRKD1 EC50 '=' 910 nM
P24723 BXGT008989 Protein kinase C eta type reviewed Kinase PRKCH EC50 '=' 910 nM
Q02156 BXGT012639 Protein kinase C epsilon type reviewed Kinase PRKCE EC50 '=' 910 nM
Q05513 BXGT012820 Protein kinase C zeta type reviewed Kinase PRKCZ EC50 '=' 910 nM
P05771 BXGT006384 Protein kinase C beta type reviewed Kinase PRKCB EC50 '=' 910 nM
Q05655 BXGT012832 Protein kinase C delta type reviewed Kinase PRKCD EC50 '=' 910 nM
P05129 BXGT006322 Protein kinase C gamma type reviewed Kinase PRKCG EC50 '=' 910 nM
P17252 BXGT008294 Protein kinase C alpha type reviewed Kinase PRKCA EC50 '=' 910 nM
P41743 BXGT010270 Protein kinase C iota type reviewed Kinase PRKCI EC50 '=' 910 nM
O94806 BXGT005335 Serine/threonine-protein kinase D3 reviewed Kinase PRKD3 EC50 '=' 910 nM
P05771 BXGT006384 Protein kinase C beta type reviewed Kinase PRKCB Activity - - -
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF02217 Euphorbia fischeriana Euphorbia fischeriana Medicinal Plant
BXGF02883 Trigonostemon howii Trigonostemon howii Others
BXGF04922 Euphorbia ebracteolata Euphorbia ebracteolata Medicinal Plant
BXGF05242 Euphorbia cornigera Euphorbia cornigera Others
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease