Showing entry for (D)-Serine


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0030028
Compound Name(D)-Serine
Structure
FormulaC3H7NO3
InchiKeyMTCFGRXMJLQNBG-UWTATZPHSA-N
SMILESOC[C@H](C(=O)O)N
InchiInChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m1/s1
IUPAC(2R)-2-amino-3-hydroxypropanoic acid
Molecular Weight105.04
Pubchem Id71077
Chembl IdCHEMBL285123
Targets of Information Source
DrugBank DB03929
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
P23415 BXGT008864 Glycine receptor subunit alpha-1 reviewed Ion channel GLRA1 approved; experimental -
Q05586 BXGT012826 Glutamate receptor ionotropic, NMDA 1 reviewed Ion channel GRIN1 approved; experimental -
P29508 BXGT009358 Serpin B3 reviewed Enzyme modulator SERPINB3 approved; experimental -
P36275 BXGT009916 Head decoration protein reviewed - shp approved; experimental -
PDB DSN
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
P35439 BXGT009831 Glutamate receptor ionotropic, NMDA 1 reviewed Grin1 - 7020 - - -
P36275 BXGT009916 Head decoration protein reviewed shp - - - - -
P01308 BXGT005749 Insulin reviewed INS - - - - -
P56254 BXGT011160 Kalata-B1 reviewed OAK1 - - - - -
P0C8P8 BXGT007452 Thiostrepton reviewed tpdA - - - - -
B5U2V4 BXGT002178 Thuricin17 unreviewed tucA1 - - - - -
Q9R1M7 BXGT021417 Glutamate receptor ionotropic, NMDA 3A reviewed Grin3a - - - - -
Q8VHN2 BXGT018931 Glutamate receptor ionotropic, NMDA 3B reviewed Grin3b - - - - -
P05129 BXGT006322 Protein kinase C gamma type reviewed PRKCG Kinase - - - -
Q63226 BXGT016063 Glutamate receptor ionotropic, delta-2 reviewed Grid2 - - - 1000000 -
P00441 BXGT005540 Superoxide dismutase [Cu-Zn] reviewed SOD1 Enzyme - - - -
A9CP13 BXGT001780 D-serine dehydratase unreviewed chDSD - - - - -
Q8IIS0 BXGT018280 D-aminoacyl-tRNA deacylase reviewed dtd - - - - -
P02640 BXGT005907 Villin-1 reviewed VIL1 - - - - -
Q8ZNT7 BXGT019225 D-cysteine desulfhydrase reviewed dcyD - - - - -
P66899 BXGT011551 Diaminopropionate ammonia-lyase reviewed ygeX - - - - -
A0A0R4I973 BXGT000600 ML032222a iGluR unreviewed ML032222a - 1700000 - - -
Q948Z4 BXGT019557 Snakin-1 reviewed SN1 - - - - -
Q8IVG9 BXGT018344 Humanin reviewed MT-RNR2 - - - - -
P62987 BXGT011478 Ubiquitin-60S ribosomal protein L40 reviewed UBA52 Nucleic acid binding - - - -
P26349 BXGT009103 Exendin-4 reviewed - - - - -
P0CG47 BXGT007467 Polyubiquitin-B reviewed UBB Nucleic acid binding - - - -
P01501 BXGT025041 Melittin reviewed MELT - - - - -
Q9RBQ1 BXGT021439 Beta-lactamase unreviewed blaL2 - - - - -
Q5M0B4 BXGT015565 Serine hydroxymethyltransferase reviewed glyA - - - - -
Binding DB 23167
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT009831 Glutamate receptor ionotropic, NMDA 1 reviewed Grin1 - 670 - -
reviewed BXGT017247 Proton-coupled amino acid transporter 1 reviewed Transporter SLC36A1 22000000 - - -
CHEMBL CHEMBL285123
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
Q7Z2H8 BXGT017247 Proton-coupled amino acid transporter 1 reviewed Transporter SLC36A1 pKi '=' -1 mM
Q9R1M7 BXGT021417 Glutamate receptor ionotropic, NMDA 3A reviewed - Grin3a EC50 '=' 200 nM
Q8VHN2 BXGT018931 Glutamate receptor ionotropic, NMDA 3B reviewed - Grin3b EC50 '=' 200 nM
Q62645 BXGT016035 Glutamate receptor ionotropic, NMDA 2D reviewed - Grin2d EC50 '=' 200 nM
Q00961 BXGT012556 Glutamate receptor ionotropic, NMDA 2C reviewed - Grin2c EC50 '=' 200 nM
Q00960 BXGT012555 Glutamate receptor ionotropic, NMDA 2B reviewed - Grin2b EC50 '=' 200 nM
Q00959 BXGT012554 Glutamate receptor ionotropic, NMDA 2A reviewed - Grin2a EC50 '=' 200 nM
P35439 BXGT009831 Glutamate receptor ionotropic, NMDA 1 reviewed - Grin1 EC50 '=' 200 nM
Q9R1M7 BXGT021417 Glutamate receptor ionotropic, NMDA 3A reviewed - Grin3a Ki '=' 316 nM
Q8VHN2 BXGT018931 Glutamate receptor ionotropic, NMDA 3B reviewed - Grin3b Ki '=' 316 nM
Q62645 BXGT016035 Glutamate receptor ionotropic, NMDA 2D reviewed - Grin2d Ki '=' 316 nM
Q00961 BXGT012556 Glutamate receptor ionotropic, NMDA 2C reviewed - Grin2c Ki '=' 316 nM
Q00960 BXGT012555 Glutamate receptor ionotropic, NMDA 2B reviewed - Grin2b Ki '=' 316 nM
Q00959 BXGT012554 Glutamate receptor ionotropic, NMDA 2A reviewed - Grin2a Ki '=' 316 nM
P35439 BXGT009831 Glutamate receptor ionotropic, NMDA 1 reviewed - Grin1 Ki '=' 316 nM
Q96KQ7 BXGT019687 Histone-lysine N-methyltransferase EHMT2 reviewed Epigenetic regulator EHMT2 Potency - 11917 nM
O15648 BXGT004185 ATP-dependent 6-phosphofructokinase reviewed - pfk Potency - 17782 nM
P35439 BXGT009831 Glutamate receptor ionotropic, NMDA 1 reviewed - Grin1 IC50 '=' 670 nM
O89049 BXGT005293 Thioredoxin reductase 1, cytoplasmic reviewed - Txnrd1 Potency - 354 nM
Q9R1M7 BXGT021417 Glutamate receptor ionotropic, NMDA 3A reviewed - Grin3a IC50 '=' 300 nM
Q8VHN2 BXGT018931 Glutamate receptor ionotropic, NMDA 3B reviewed - Grin3b IC50 '=' 300 nM
Q62645 BXGT016035 Glutamate receptor ionotropic, NMDA 2D reviewed - Grin2d IC50 '=' 300 nM
Q00961 BXGT012556 Glutamate receptor ionotropic, NMDA 2C reviewed - Grin2c IC50 '=' 300 nM
Q00960 BXGT012555 Glutamate receptor ionotropic, NMDA 2B reviewed - Grin2b IC50 '=' 300 nM
Q00959 BXGT012554 Glutamate receptor ionotropic, NMDA 2A reviewed - Grin2a IC50 '=' 300 nM
P35439 BXGT009831 Glutamate receptor ionotropic, NMDA 1 reviewed - Grin1 IC50 '=' 300 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 2985 nM
Q96KQ7 BXGT019687 Histone-lysine N-methyltransferase EHMT2 reviewed Epigenetic regulator EHMT2 Potency - 22 nM
Q7Z2H8 BXGT017247 Proton-coupled amino acid transporter 1 reviewed Transporter SLC36A1 Ki '=' 22000000 nM
Q9R1M7 BXGT021417 Glutamate receptor ionotropic, NMDA 3A reviewed - Grin3a EC50 '=' 160 nM
Q8VHN2 BXGT018931 Glutamate receptor ionotropic, NMDA 3B reviewed - Grin3b EC50 '=' 160 nM
Q62645 BXGT016035 Glutamate receptor ionotropic, NMDA 2D reviewed - Grin2d EC50 '=' 160 nM
Q00961 BXGT012556 Glutamate receptor ionotropic, NMDA 2C reviewed - Grin2c EC50 '=' 160 nM
Q00960 BXGT012555 Glutamate receptor ionotropic, NMDA 2B reviewed - Grin2b EC50 '=' 160 nM
Q00959 BXGT012554 Glutamate receptor ionotropic, NMDA 2A reviewed - Grin2a EC50 '=' 160 nM
P35439 BXGT009831 Glutamate receptor ionotropic, NMDA 1 reviewed - Grin1 EC50 '=' 160 nM
Q12809 BXGT013267 Potassium voltage-gated channel subfamily H member 2 reviewed Ion channel KCNH2 Potency - 35481 nM
P49798 BXGT010745 Regulator of G-protein signaling 4 reviewed Enzyme modulator RGS4 Potency - 843 nM
Q91Y77 BXGT019323 Monocarboxylate transporter 10 reviewed - Slc16a10 Activity - - -
P54132 BXGT011032 Bloom syndrome protein reviewed - BLM Potency '=' 2 nM
Q9Z1J7 BXGT022405 Amino acid transporter unreviewed - Slc1a5 IC50 '=' 1581000 nM
P02545 BXGT005889 Prelamin-A/C reviewed - LMNA Potency '=' 12589 nM
Q15758 BXGT013594 Neutral amino acid transporter B(0) reviewed Transporter SLC1A5 IC50 '=' 4913000 nM
Q9Z1J7 BXGT022405 Amino acid transporter unreviewed - Slc1a5 IC50 '=' 2592000 nM
P43007 BXGT010350 Neutral amino acid transporter A reviewed Transporter SLC1A4 IC50 '=' 3937000 nM
P63116 BXGT011501 Asc-type amino acid transporter 1 reviewed - Slc7a10 IC50 '=' 9400 nM
Q9Z1J7 BXGT022405 Amino acid transporter unreviewed - Slc1a5 Inhibition '>=' 25 %
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00008 Garlic Allium sativum Herbs and Spices
BXGF00027 Chinese mustard Brassica juncea Vegetables
BXGF00200 Mung bean Vigna radiata Pulses
BXGF00337 Ginkgo nuts Ginkgo biloba Herbs and Spices
BXGF00380 White mustard Sinapis alba Herbs and Spices
BXGF01140 Angelica gigas Angelica gigas Medicinal Plant
BXGF02049 Angelica sinensis Angelica sinensis Medicinal Plant
BXGF03490 Atractylodes macrocephala koidz Atractylodes macrocephala koidz Others
BXGF04842 Angelica acutiloba Angelica acutiloba Medicinal Plant
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease