Showing entry for D-Aspartate


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0038154
Compound NameD-Aspartate
Structure
FormulaC4H7NO4
InchiKeyCKLJMWTZIZZHCS-UWTATZPHSA-N
SMILESOC(=O)C[C@H](C(=O)O)N
InchiInChI=1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/t2-/m1/s1
IUPAC(2R)-2-aminobutanedioic acid
Molecular Weight133.04
Pubchem Id83887
Chembl IdCHEMBL29757
Targets of Information Source
DrugBank DB02655
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
P43133 BXGT010359 Thermolysin reviewed - nprS experimental -
P06608 BXGT006456 L-asparaginase reviewed - ansB experimental -
PDB DAS
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
P00761 BXGT005645 Trypsin reviewed - - - - -
P06608 BXGT006456 L-asparaginase reviewed ansB - - - - -
P00800 BXGT005661 Thermolysin reviewed npr - - - - -
P02640 BXGT005907 Villin-1 reviewed VIL1 - - - - -
Q948Z4 BXGT019557 Snakin-1 reviewed SN1 - - - - -
P62987 BXGT011478 Ubiquitin-60S ribosomal protein L40 reviewed UBA52 Nucleic acid binding - - - -
Q9RNB4 BXGT021477 McyF unreviewed mcyF - - - - -
Q484B6 BXGT014749 Isoaspartyl dipeptidase unreviewed iadA - - - - -
P0CG47 BXGT007467 Polyubiquitin-B reviewed UBB Nucleic acid binding - - - -
P01275 BXGT005747 Glucagon reviewed GCG - - - - -
Q5JID0 BXGT015445 Proton/glutamate symporter, SDF family unreviewed TK0986 - - - - -
Binding DB 31174
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT009831 Glutamate receptor ionotropic, NMDA 1 reviewed Grin1 800 - - -
reviewed BXGT009831 Glutamate receptor ionotropic, NMDA 1 reviewed Grin1 900 - - -
reviewed BXGT009831 Glutamate receptor ionotropic, NMDA 1 reviewed Grin1 >10000 - - -
reviewed BXGT004150 Metabotropic glutamate receptor 6 reviewed G-protein coupled receptor GRM6 - - - >1000000
reviewed BXGT013468 Metabotropic glutamate receptor 2 reviewed G-protein coupled receptor GRM2 - - - >1000000
reviewed BXGT013332 Metabotropic glutamate receptor 1 reviewed G-protein coupled receptor GRM1 - - - >1000000
CHEMBL CHEMBL29757
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
P05177 BXGT006336 Cytochrome P450 1A2 reviewed Enzyme CYP1A2 AC50 - - -
P33261 BXGT009707 Cytochrome P450 2C19 reviewed - CYP2C19 AC50 - - -
P10635 BXGT007595 Cytochrome P450 2D6 reviewed - CYP2D6 AC50 - - -
Q9F4F7 BXGT020344 4'-phosphopantetheinyl transferase ffp reviewed - ffp Potency '=' 79432 nM
O15303 BXGT004150 Metabotropic glutamate receptor 6 reviewed G-protein coupled receptor GRM6 EC50 '>' 1000000 nM
Q9F4F7 BXGT020344 4'-phosphopantetheinyl transferase ffp reviewed - ffp Potency '=' 14125 nM
Q14416 BXGT013468 Metabotropic glutamate receptor 2 reviewed G-protein coupled receptor GRM2 EC50 '>' 1000000 nM
P11712 BXGT007738 Cytochrome P450 2C9 reviewed - CYP2C9 AC50 - - -
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 33498 nM
O59010 BXGT004824 Glutamate transporter homolog reviewed - PH1295 Kd '=' 10 nM
Q9R1M7 BXGT021417 Glutamate receptor ionotropic, NMDA 3A reviewed - Grin3a IC50 '=' 10000 nM
Q8VHN2 BXGT018931 Glutamate receptor ionotropic, NMDA 3B reviewed - Grin3b IC50 '=' 10000 nM
Q62645 BXGT016035 Glutamate receptor ionotropic, NMDA 2D reviewed - Grin2d IC50 '=' 10000 nM
Q00961 BXGT012556 Glutamate receptor ionotropic, NMDA 2C reviewed - Grin2c IC50 '=' 10000 nM
Q00960 BXGT012555 Glutamate receptor ionotropic, NMDA 2B reviewed - Grin2b IC50 '=' 10000 nM
Q00959 BXGT012554 Glutamate receptor ionotropic, NMDA 2A reviewed - Grin2a IC50 '=' 10000 nM
P35439 BXGT009831 Glutamate receptor ionotropic, NMDA 1 reviewed - Grin1 IC50 '=' 10000 nM
P27695 BXGT009199 DNA-(apurinic or apyrimidinic site) lyase reviewed - APEX1 Potency - 158 nM
P16473 BXGT008234 Thyrotropin receptor reviewed G-protein coupled receptor TSHR Potency '=' 7943 nM
Q13255 BXGT013332 Metabotropic glutamate receptor 1 reviewed G-protein coupled receptor GRM1 EC50 '>' 1000000 nM
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 AC50 - - -
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00008 Garlic Allium sativum Herbs and Spices
BXGF00027 Chinese mustard Brassica juncea Vegetables
BXGF00337 Ginkgo nuts Ginkgo biloba Herbs and Spices
BXGF00380 White mustard Sinapis alba Herbs and Spices
BXGF01185 Aloe vera Aloe vera Medicinal Plant
BXGF01333 Leontice robustum Leontice robustum Medicinal Plant
BXGF01900 Aloe ferox Aloe ferox Medicinal Plant
BXGF01911 Bupleurum scorzonerifolium Bupleurum scorzonerifolium Medicinal Plant
BXGF02815 Pinellia ternata Pinellia ternata Medicinal Plant
BXGF02965 Arabidopsis thaliana Arabidopsis thaliana Medicinal Plant
BXGF03359 Amomum melegueta Amomum melegueta Medicinal Plant
BXGF04471 Otholobium glandulosum Otholobium glandulosum Medicinal Plant
BXGF04483 Terminalia brachystemma Terminalia brachystemma Others
BXGF04494 Raoulia australis Raoulia australis Others
BXGF04507 Anacyclus monanthos Anacyclus monanthos Others
BXGF04516 Ulmus campestris Ulmus campestris Medicinal Plant
BXGF04554 Corydalis tashiroi Corydalis tashiroi Others
BXGF04562 Senecio chionophilus Senecio chionophilus Others
BXGF04592 Prunus speciosa Prunus speciosa Others
BXGF04612 Mikania cordifolia Mikania cordifolia Medicinal Plant
BXGF04619 Hakea trifurcata Hakea trifurcata Others
BXGF04624 Astragalus siculus Astragalus siculus Others
BXGF04631 Aloe spicata Aloe spicata Medicinal Plant
BXGF04652 Guizotia scabra Guizotia scabra Medicinal Plant
BXGF04669 Euphorbia cuneata Euphorbia cuneata Medicinal Plant
BXGF04672 Arum palaestinum Arum palaestinum Medicinal Plant
BXGF04872 Glycyrrhiza glabra Glycyrrhiza glabra Medicinal Plant
BXGF04875 Bupleurum chinense Bupleurum chinense Medicinal Plant
BXGF04889 Pogostemon cablin Pogostemon cablin Medicinal Plant
BXGF04926 Aloe africana Aloe africana Medicinal Plant
BXGF04981 Bupleurum falcatum Bupleurum falcatum Medicinal Plant
BXGF05421 Tussilago farfara Tussilago farfara Medicinal Plant
BXGF05511 Acorus gramineus Acorus gramineus Medicinal Plant
BXGF06071 Acorus tatarinowii Acorus tatarinowii Medicinal Plant
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease