acompound

Showing entry for Eriodictyol

General Compound Information
BXGC Id	BXGC0039476
Compound Name	Eriodictyol
Structure
Formula	C15H12O6
InchiKey	SBHXYTNGIZCORC-ZDUSSCGKSA-N
SMILES	Oc1cc2O[C@@H](CC(=O)c2c(c1)O)c1ccc(c(c1)O)O
Inchi	InChI=1S/C15H12O6/c16-8-4-11(19)15-12(20)6-13(21-14(15)5-8)7-1-2-9(17)10(18)3-7/h1-5,13,16-19H,6H2/t13-/m0/s1
IUPAC	(2S)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-2,3-dihydrochromen-4-one
Molecular Weight	288.06
Pubchem Id	440735
Chembl Id	CHEMBL8996

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

ERD

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
P51110	BXGT010831	Dihydroflavonol 4-reductase	reviewed	DFR	-	-	-	-	-

Binding DB

50325671

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT006753	Heat shock protein HSP 90-beta	reviewed	Chaperone	HSP90AB1	-	200	-	-
reviewed	BXGT005690	Carbonic anhydrase 2	reviewed		CA2	>10000	-	-	-
reviewed	BXGT005689	Carbonic anhydrase 1	reviewed		CA1	>10000	-	-	-
reviewed	BXGT008802	Carbonic anhydrase 4	reviewed		CA4	73	-	-	-
reviewed	BXGT010364	Carbonic anhydrase 7	reviewed		CA7	4.3	-	-	-
reviewed	BXGT004601	Carbonic anhydrase 12	reviewed		CA12	31	-	-	-
reviewed	BXGT006265	Cytochrome P450 1A1	reviewed	Enzyme	CYP1A1	-	10973	-	-
reviewed	BXGT013656	Cytochrome P450 1B1	reviewed	Enzyme	CYP1B1	-	1284	-	-
reviewed	BXGT008751	Acetylcholinesterase	reviewed	Enzyme	ACHE	-	1663800	-	-
reviewed	BXGT009938	Receptor-type tyrosine-protein kinase FLT3	reviewed	Kinase	FLT3	-	>10000	-	-

CHEMBL

CHEMBL8996

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P81908	BXGT011959	Cholinesterase	reviewed	-	BCHE	Inhibition	'='	0	%
P22303	BXGT008751	Acetylcholinesterase	reviewed	Enzyme	ACHE	IC50	'='	1663800	nM
O42713	BXGT004563	Polyphenol oxidase 2	reviewed	-	PPO2	Inhibition	-	-	-
P80457	BXGT011911	Xanthine dehydrogenase/oxidase	reviewed	-	XDH	Inhibition	'='	47	%
P04798	BXGT006265	Cytochrome P450 1A1	reviewed	Enzyme	CYP1A1	IC50	'='	10973	nM
P47199	BXGT010568	Quinone oxidoreductase	reviewed	-	Cryz	CD	'>'	10	ug ml-1
O42713	BXGT004563	Polyphenol oxidase 2	reviewed	-	PPO2	Inhibition	'<'	10	%
Q16678	BXGT013656	Cytochrome P450 1B1	reviewed	Enzyme	CYP1B1	IC50	'='	1284	nM
P36888	BXGT009938	Receptor-type tyrosine-protein kinase FLT3	reviewed	Kinase	FLT3	IC50	'>'	10000	nM
O42275	BXGT004559	Acetylcholinesterase	reviewed	-	ache	Inhibition	'='	20	%
O43570	BXGT004601	Carbonic anhydrase 12	reviewed	-	CA12	Ki	'='	31	nM
Q9N1N9	BXGT021115	Carboxylic ester hydrolase	unreviewed	-	BCHE	IC50	'='	1124400	nM
Q9N1N9	BXGT021115	Carboxylic ester hydrolase	unreviewed	-	BCHE	Ki	-	-	-
Q60795	BXGT016000	Nuclear factor erythroid 2-related factor 2	reviewed	-	Nfe2l2	FC	'='	1	-
P05177	BXGT006336	Cytochrome P450 1A2	reviewed	Enzyme	CYP1A2	IC50	'='	53214	nM
P22303	BXGT008751	Acetylcholinesterase	reviewed	Enzyme	ACHE	Ki	-	-	-
P00918	BXGT005690	Carbonic anhydrase 2	reviewed	-	CA2	Ki	'>'	10000	nM
P22748	BXGT008802	Carbonic anhydrase 4	reviewed	-	CA4	Ki	'='	72	nM
P43166	BXGT010364	Carbonic anhydrase 7	reviewed	-	CA7	Ki	'='	4	nM
P00915	BXGT005689	Carbonic anhydrase 1	reviewed	-	CA1	Ki	'>'	10000	nM

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00055	Pummelo	Citrus maxima	Fruits
BXGF00183	Common thyme	Thymus vulgaris	Herbs and Spices
BXGF00432	Sesbania flower	Sesbania bispinosa	Vegetables
BXGF00851	Myrsine capitellata	Myrsine capitellata	Medicinal Plant
BXGF00870	Othonna sedifolia	Othonna sedifolia	Others
BXGF00878	Lespedeza bicolor	Lespedeza bicolor	Medicinal Plant
BXGF00901	Ipomoea muricata	Ipomoea muricata	Medicinal Plant
BXGF00945	Chrysanthemum sinense	Chrysanthemum sinense	Others
BXGF01115	Eriodictyon californicum	Eriodictyon californicum	Medicinal Plant
BXGF01122	Sideritis trojana	Sideritis trojana	Others
BXGF01145	Pterocarpus officinalis	Pterocarpus officinalis	Medicinal Plant
BXGF01177	Vernonia lanuginosa	Vernonia lanuginosa	Others
BXGF01188	Calycanthus floridus	Calycanthus floridus	Medicinal Plant
BXGF01200	Markhamia stipulata	Markhamia stipulata	Medicinal Plant
BXGF01208	Angelica lucida	Angelica lucida	Human Edible Plant
BXGF01229	Strophanthus kombe	Strophanthus kombe	Medicinal Plant
BXGF01271	Castanea vesca	Castanea vesca	Others
BXGF01319	Adenia globosa	Adenia globosa	Others
BXGF01342	Hypericum reflexum	Hypericum reflexum	Others
BXGF01364	Vinca minor	Vinca minor	Human Edible Plant
BXGF01403	Aglaia grandis	Aglaia grandis	Medicinal Plant
BXGF01429	Osteospermum fruticosum	Osteospermum fruticosum	Others
BXGF01433	Catunaregam tomentosa	Catunaregam tomentosa	Human Edible Plant
BXGF01461	Liriodendron tulipifera	Liriodendron tulipifera	Medicinal Plant
BXGF01506	Thymus quinquecostatus	Thymus quinquecostatus	Medicinal Plant
BXGF01539	Euphrasia stricta	Euphrasia stricta	Others
BXGF01626	Nerine bowdenii	Nerine bowdenii	Others
BXGF01629	Satureja odora	Satureja odora	Medicinal Plant
BXGF01630	Cotula cinerea	Cotula cinerea	Medicinal Plant
BXGF01706	Daphniphyllum paxianum	Daphniphyllum paxianum	Others
BXGF01826	Hypericum hirsutum	Hypericum hirsutum	Medicinal Plant
BXGF02048	Sideritis soluta	Sideritis soluta	Others
BXGF02155	Chrysanthemum uliginosum	Chrysanthemum uliginosum	Others
BXGF02323	Dalbergia hupeana	Dalbergia hupeana	Medicinal Plant
BXGF02403	Eucalyptus radiata	Eucalyptus radiata	Human Edible Plant
BXGF02528	Cirsium oligophyllum	Cirsium oligophyllum	Medicinal Plant
BXGF02940	Conyza japonica	Conyza japonica	Medicinal Plant
BXGF03050	Dracocephalum tanguticum	Dracocephalum tanguticum	Others
BXGF03110	Gleditsia sinensis	Gleditsia sinensis	Medicinal Plant
BXGF03219	Hymenoxys insignis	Hymenoxys insignis	Others
BXGF03247	Anastatica hierochuntica	Anastatica hierochuntica	Medicinal Plant
BXGF03303	Psorothamnus polydenius	Psorothamnus polydenius	Others
BXGF03312	Ajania fruticulosa	Ajania fruticulosa	Medicinal Plant
BXGF03346	Dendrobium candidum	Dendrobium candidum	Others
BXGF03392	Paulownia tomentosa	Paulownia tomentosa	Medicinal Plant
BXGF03572	Calicotome villosa	Calicotome villosa	Medicinal Plant
BXGF03672	Erysimum siliculosum	Erysimum siliculosum	Others
BXGF04150	Erycibe expansa	Erycibe expansa	Medicinal Plant
BXGF04263	Glycine soja	Glycine soja	Medicinal Plant
BXGF04300	Tetrapanax papyrifer	Tetrapanax papyrifer	Medicinal Plant
BXGF04301	Dorstenia dinklagei	Dorstenia dinklagei	Others
BXGF04328	Croton zehntneri	Croton zehntneri	Others
BXGF04750	Scutellaria baicalensis	Scutellaria baicalensis	Medicinal Plant
BXGF04772	Sapium haematospermum	Sapium haematospermum	Medicinal Plant
BXGF04785	Ilex taubertiana	Ilex taubertiana	Others
BXGF04910	Spinulum annotinum	Spinulum annotinum	Medicinal Plant
BXGF04967	Cudrania tricuspidata	Cudrania tricuspidata	Medicinal Plant
BXGF04997	Geum japonicum	Geum japonicum	Medicinal Plant
BXGF05195	Limonium sinense	Limonium sinense	Others
BXGF05204	Erigeron breviscapus	Erigeron breviscapus	Medicinal Plant
BXGF05399	Zanthoxylum myriacanthum	Zanthoxylum myriacanthum	Medicinal Plant
BXGF05456	Anaphalis araneosa	Anaphalis araneosa	Others
BXGF05492	Bhesa nitidissima	Bhesa nitidissima	Others
BXGF05522	Solidago serotina	Solidago serotina	Others
BXGF05590	Peucedanum ostruthium	Peucedanum ostruthium	Medicinal Plant
BXGF05626	Annona glabra	Annona glabra	Medicinal Plant
BXGF05643	Viguiera stenoloba	Viguiera stenoloba	Others
BXGF05689	Artemisia klotzchiana	Artemisia klotzchiana	Others
BXGF05720	Camchaya loloana	Camchaya loloana	Others
BXGF05724	Rothmannia wittii	Rothmannia wittii	Medicinal Plant
BXGF05732	Mimusops caffra	Mimusops caffra	Human Edible Plant
BXGF05788	Mollugo spergula	Mollugo spergula	Medicinal Plant
BXGF05809	Sonchus oleraceus	Sonchus oleraceus	Medicinal Plant
BXGF05846	Ranzania japonica	Ranzania japonica	Others
BXGF05867	Asphodelus tenuifolius	Asphodelus tenuifolius	Medicinal Plant
BXGF05876	Gleditsia japonica	Gleditsia japonica	Medicinal Plant
BXGF05904	Impatiens edgeworthii	Impatiens edgeworthii	Others
BXGF05940	Artemisia kurramensis	Artemisia kurramensis	Others
BXGF05965	Episcia cupreata	Episcia cupreata	Others
BXGF05967	Veronica arvensis	Veronica arvensis	Medicinal Plant
BXGF06052	Astragalus curvicarpus	Astragalus curvicarpus	Others
BXGF06115	Kaempferia rotunda	Kaempferia rotunda	Medicinal Plant
BXGF06167	Sorbaria sorbifolia	Sorbaria sorbifolia	Medicinal Plant
BXGF06168	Nicotiana affinis	Nicotiana affinis	Others
BXGF06183	Adina sessilifolia	Adina sessilifolia	Others
BXGF06186	Jasonia candicans	Jasonia candicans	Others
BXGF06222	Senecio sandersonii	Senecio sandersonii	Others

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}