Showing entry for Quinizarin


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0053494
Compound NameQuinizarin
Structure
FormulaC14H8O4
InchiKeyGUEIZVNYDFNHJU-UHFFFAOYSA-N
SMILESOc1ccc(c2c1C(=O)c1ccccc1C2=O)O
InchiInChI=1S/C14H8O4/c15-9-5-6-10(16)12-11(9)13(17)7-3-1-2-4-8(7)14(12)18/h1-6,15-16H
IUPAC1,4-dihydroxyanthracene-9,10-dione
Molecular Weight240.04
Pubchem Id6688
Chembl IdCHEMBL17594
Targets of Information Source
DrugBank n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
PDB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Binding DB 50240382
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT010656 Casein kinase I isoform delta reviewed Kinase CSNK1D - >40000 - -
reviewed BXGT020536 Casein kinase I isoform gamma-1 reviewed Kinase CSNK1G1 - >40000 - -
reviewed BXGT010655 Casein kinase I isoform alpha reviewed Kinase CSNK1A1 - >40000 - -
reviewed BXGT005293 Thioredoxin reductase 1, cytoplasmic reviewed Txnrd1 - >200000 - -
reviewed BXGT022399 Thioredoxin reductase 2, mitochondrial reviewed Txnrd2 - >200000 - -
CHEMBL CHEMBL17594
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
Q9F4F7 BXGT020344 4'-phosphopantetheinyl transferase ffp reviewed - ffp Potency '=' 79432 nM
P03372 BXGT006059 Estrogen receptor reviewed Nuclear receptor ESR1 Control '=' 106 %
Q92731 BXGT019366 Estrogen receptor beta reviewed Nuclear receptor ESR2 Control '=' 106 %
Q13951 BXGT013407 Core-binding factor subunit beta reviewed - CBFB Potency - 12589 nM
Q01196 BXGT012575 Runt-related transcription factor 1 reviewed Transcription factor RUNX1 Potency - 12589 nM
P10636 BXGT007596 Microtubule-associated protein tau reviewed - MAPT Potency '=' 1995 nM
P19224 BXGT008468 UDP-glucuronosyltransferase 1-6 reviewed - UGT1A6 Activity '=' 0 pm/min/mg
Q03164 BXGT012700 Histone-lysine N-methyltransferase 2A reviewed - KMT2A Potency '=' 12589 nM
O00255 BXGT003903 Menin reviewed - MEN1 Potency '=' 12589 nM
Q9HCP0 BXGT020536 Casein kinase I isoform gamma-1 reviewed Kinase CSNK1G1 IC50 '>' 40000 nM
Q9Z0J5 BXGT022399 Thioredoxin reductase 2, mitochondrial reviewed - Txnrd2 IC50 '>' 200000 nM
P03372 BXGT006059 Estrogen receptor reviewed Nuclear receptor ESR1 Control '=' 104 %
Q92731 BXGT019366 Estrogen receptor beta reviewed Nuclear receptor ESR2 Control '=' 104 %
P48730 BXGT010656 Casein kinase I isoform delta reviewed Kinase CSNK1D IC50 '>' 40000 nM
O60656 BXGT004889 UDP-glucuronosyltransferase 1-9 reviewed - UGT1A9 Activity '=' 40 pm/min/mg
P48729 BXGT010655 Casein kinase I isoform alpha reviewed Kinase CSNK1A1 IC50 '>' 40000 nM
P03372 BXGT006059 Estrogen receptor reviewed Nuclear receptor ESR1 Control '=' 109 %
Q92731 BXGT019366 Estrogen receptor beta reviewed Nuclear receptor ESR2 Control '=' 109 %
P10636 BXGT007596 Microtubule-associated protein tau reviewed - MAPT Potency '=' 14125 nM
P22309 BXGT008753 UDP-glucuronosyltransferase 1-1 reviewed - UGT1A1 Activity '=' 17 pm/min/mg
P22309 BXGT008753 UDP-glucuronosyltransferase 1-1 reviewed - UGT1A1 Activity '=' 0 pm/min/mg
O89049 BXGT005293 Thioredoxin reductase 1, cytoplasmic reviewed - Txnrd1 IC50 '>' 200000 nM
P11473 BXGT007709 Vitamin D3 receptor reviewed Nuclear receptor VDR Potency - 44668 nM
P22310 BXGT008754 UDP-glucuronosyltransferase 1-4 reviewed - UGT1A4 Activity '=' 0 pm/min/mg
P54855 BXGT011088 UDP-glucuronosyltransferase 2B15 reviewed - UGT2B15 Activity '=' 0 pm/min/mg
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF01126 Polygonum cuspidatum Polygonum cuspidatum Medicinal Plant
BXGF04917 Cassia obtusifolia Cassia obtusifolia Medicinal Plant
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease