Showing entry for Protein-glutamine gamma-glutamyltransferase E


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT012965
Protein NameProtein-glutamine gamma-glutamyltransferase E
Uniport IdQ08188
GeneTGM3
Gene Id7053
DomainTransglut_C; Transglut_core; Transglut_N
Pfam PF00927   PF01841   PF00868  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0043163 cell envelope organization
Biological Process GO:0006464 cellular protein modification process
Biological Process GO:0031069 hair follicle morphogenesis
Biological Process GO:0031424 keratinization
Biological Process GO:0030216 keratinocyte differentiation
Biological Process GO:0018149 peptide cross-linking
molecular function GO:0005509 calcium ion binding
molecular function GO:0003824 catalytic activity
molecular function GO:0003810 protein-glutamine gamma-glutamyltransferase activity
molecular function GO:0005198 structural molecule activity
molecular function GO:0016746 transferase activity, transferring acyl groups
cellular component GO:0005737 cytoplasm
cellular component GO:0070062 extracellular exosome
cellular component GO:0031234 extrinsic component of cytoplasmic side of plasma membrane
cellular component GO:0032991 protein-containing complex
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002171 BXGD000106 Alopecia Areata Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007114 BXGD000431 Malignant neoplasm of skin Neoplasms; Skin and Connective Tissue Diseases
C0007117 BXGD000433 Basal cell carcinoma Neoplasms
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0011603 BXGD000734 Dermatitis Skin and Connective Tissue Diseases
C0011608 BXGD000736 Dermatitis Herpetiformis Skin and Connective Tissue Diseases; Immune System Diseases
C0011615 BXGD000738 Dermatitis, Atopic Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Immune System Diseases
C0013595 BXGD000858 Eczema Skin and Connective Tissue Diseases
C0014527 BXGD000923 Epidermolysis Bullosa Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0014859 BXGD000961 Esophageal Neoplasms Digestive System Diseases; Neoplasms
C0020179 BXGD001363 Huntington Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders
C0022595 BXGD001562 Keratosis Follicularis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0023531 BXGD001684 Leukoplakia Pathological Conditions, Signs and Symptoms; Neoplasms
C0023532 BXGD001685 Leukoplakia, Oral Pathological Conditions, Signs and Symptoms; Neoplasms; Stomatognathic Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0033860 BXGD002438 Psoriasis Skin and Connective Tissue Diseases
C0037274 BXGD002676 Dermatologic disorders Skin and Connective Tissue Diseases
C0079584 BXGD003083 Ichthyosis Vulgaris Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0152018 BXGD003518 Esophageal carcinoma Digestive System Diseases; Neoplasms
C0206139 BXGD004159 Lichen Planus, Oral Skin and Connective Tissue Diseases; Stomatognathic Diseases
C0206710 BXGD004258 Basal Cell Neoplasm Neoplasms
C0239804 BXGD004995 White hair
C0266929 BXGD005722 Chronic Periodontitis Stomatognathic Diseases
C0275524 BXGD006376 Coinfection Infections
C0277959 BXGD006487 Coarse hair
C0278996 BXGD006621 Malignant Head and Neck Neoplasm Neoplasms
C0279626 BXGD006657 Squamous cell carcinoma of esophagus Digestive System Diseases; Neoplasms
C0302254 BXGD006834 Juvenile cataract Eye Diseases
C0343073 BXGD007597 Wooly hair Skin and Connective Tissue Diseases
C0432347 BXGD008779 Uncombable hair syndrome Skin and Connective Tissue Diseases
C0546837 BXGD009343 Malignant neoplasm of esophagus Digestive System Diseases; Neoplasms
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0751676 BXGD010549 Basal Cell Cancer Neoplasms
C0878500 BXGD011365 Intraepithelial Neoplasia Neoplasms
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1608408 BXGD013434 Malignant transformation
C1860607 BXGD015990 Uncombable hair
C1860608 BXGD015991 Pili canaliculi
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C3811653 BXGD019662 Experimental Organism Basal Cell Carcinoma Neoplasms
C3875321 BXGD019874 Inflammatory dermatosis Skin and Connective Tissue Diseases
C3887461 BXGD019876 Head and Neck Carcinoma Neoplasms
C4025700 BXGD021740 Trichodysplasia
C4721806 BXGD023772 Carcinoma, Basal Cell Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002586 Calcium 40.08
BXGC0002588 Magnesium 24.31
BXGC0003705 Chloride 35.45
BXGC0027925 Cpg 363.06
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein