Showing entry for Hereditary Nonpolyposis Colorectal Neoplasms


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD000607
Disease NameHereditary Nonpolyposis Colorectal Neoplasms
Disease CUI IdC0009405
MeSH Codes C16   C06   C04   C18  
Disease Class NameCongenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Neoplasms; Nutritional and Metabolic Diseases
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:630  
Disease Ontology Class Namegenetic disease
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O14965 BXGT004117 Aurora kinase A 6790 reviewed Kinase
O96017 BXGT005415 Serine/threonine-protein kinase Chk2 11200 reviewed Kinase
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P04798 BXGT006265 Cytochrome P450 1A1 1543 reviewed Enzyme
P05067 BXGT006306 Amyloid-beta precursor protein 351 reviewed Enzyme modulator
P05093 BXGT006313 Steroid 17-alpha-hydroxylase/17,20 lyase 1586 reviewed
P07099 BXGT006546 Epoxide hydrolase 1 2052 reviewed
P12830 BXGT007852 Cadherin-1 999 reviewed
P15056 BXGT008075 Serine/threonine-protein kinase B-raf 673 reviewed Kinase
P15941 BXGT008176 Mucin-1 4582 reviewed
P16070 BXGT008186 CD44 antigen 960 reviewed
P21964 BXGT008714 Catechol O-methyltransferase 1312 reviewed Enzyme
P29466 BXGT009349 Caspase-1 834 reviewed Enzyme
P35221 BXGT009798 Catenin alpha-1 1495 reviewed Cellular structure
P37173 BXGT009970 TGF-beta receptor type-2 7048 reviewed Kinase
P40692 BXGT010195 DNA mismatch repair protein Mlh1 4292 reviewed Nucleic acid binding
P43246 BXGT010371 DNA mismatch repair protein Msh2 4436 reviewed Nucleic acid binding
P46527 BXGT010525 Cyclin-dependent kinase inhibitor 1B 1027 reviewed
P51532 BXGT010852 Transcription activator BRG1 6597 reviewed Epigenetic regulator
P52701 BXGT010943 DNA mismatch repair protein Msh6 2956 reviewed Nucleic acid binding
P54278 BXGT011038 Mismatch repair endonuclease PMS2 5395 reviewed Nucleic acid binding
Q05823 BXGT012840 2-5A-dependent ribonuclease 6041 reviewed Kinase
Q07812 BXGT012940 Apoptosis regulator BAX 581 reviewed Signaling
Q12913 BXGT013279 Receptor-type tyrosine-protein phosphatase eta 5795 reviewed Enzyme
Q13315 BXGT013339 Serine-protein kinase ATM 472 reviewed Kinase
Q13426 BXGT013353 DNA repair protein XRCC4 7518 reviewed
Q16790 BXGT013670 Carbonic anhydrase 9 768 reviewed
Q86YC2 BXGT017633 Partner and localizer of BRCA2 79728 reviewed
Q99728 BXGT019956 BRCA1-associated RING domain protein 1 580 reviewed
Q9UQ84 BXGT021807 Exonuclease 1 9156 reviewed Enzyme
Q9Y2M0 BXGT022241 Fanconi-associated nuclease 1 22909 reviewed
P25054 BXGT022961 Adenomatous polyposis coli protein 324 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease