Showing entry for Pemphigus Vulgaris


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD002258
Disease NamePemphigus Vulgaris
Disease CUI IdC0030809
MeSH Codes C17   C20  
Disease Class NameSkin and Connective Tissue Diseases; Immune System Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:7  
Disease Ontology Class Namedisease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O14672 BXGT004081 Disintegrin and metalloproteinase domain-containing protein 10 102 reviewed
O75369 BXGT005119 Filamin-B 2317 reviewed
O76054 BXGT005172 SEC14-like protein 2 23541 reviewed
P00441 BXGT005540 Superoxide dismutase [Cu-Zn] 6647 reviewed Enzyme
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P00747 BXGT005639 Plasminogen 5340 reviewed Enzyme
P00749 BXGT005641 Urokinase-type plasminogen activator 5328 reviewed Enzyme
P01024 BXGT005719 Complement C3 718 reviewed Enzyme modulator
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01308 BXGT005749 Insulin 3630 reviewed
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01579 BXGT005770 Interferon gamma 3458 reviewed
P01583 BXGT005771 Interleukin-1 alpha 3552 reviewed
P01889 BXGT005809 HLA class I histocompatibility antigen, B-7 alpha chain 3106 reviewed
P01903 BXGT005814 HLA class II histocompatibility antigen, DR alpha chain 3122 reviewed Immune response
P01909 BXGT005815 HLA class II histocompatibility antigen, DQ alpha 1 chain 3117 reviewed Immune response
P01911 BXGT005816 HLA class II histocompatibility antigen, DRB1-15 beta chain 3123 reviewed Immune response
P01920 BXGT005817 HLA class II histocompatibility antigen, DQ beta 1 chain 3119 reviewed Immune response
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P04150 BXGT006154 Glucocorticoid receptor 2908 reviewed Nuclear receptor
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P05120 BXGT006319 Plasminogen activator inhibitor 2 5055 reviewed Enzyme modulator
P05231 BXGT006345 Interleukin-6 3569 reviewed
P07900 BXGT006696 Heat shock protein HSP 90-alpha 3320 reviewed Chaperone
P08235 BXGT006751 Mineralocorticoid receptor 4306 reviewed Nuclear receptor
P08686 BXGT006813 Steroid 21-hydroxylase 1589 reviewed
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10747 BXGT007609 T-cell-specific surface glycoprotein CD28 940 reviewed
P12830 BXGT007852 Cadherin-1 999 reviewed
P14174 BXGT007991 Macrophage migration inhibitory factor 4282 reviewed
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P15924 BXGT008171 Desmoplakin 1832 reviewed Cellular structure
P16410 BXGT008224 Cytotoxic T-lymphocyte protein 4 1493 reviewed
P17252 BXGT008294 Protein kinase C alpha type 5578 reviewed Kinase
P19838 BXGT008526 Nuclear factor NF-kappa-B p105 subunit 4790 reviewed Transcription factor
P22897 BXGT008816 Macrophage mannose receptor 1 4360 reviewed
P24941 BXGT009002 Cyclin-dependent kinase 2 1017 reviewed Kinase
P26358 BXGT009104 DNA (cytosine-5)-methyltransferase 1 1786 reviewed Epigenetic regulator
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P29323 BXGT009334 Ephrin type-B receptor 2 2048 reviewed Kinase
P32926 BXGT009680 Desmoglein-3 1830 reviewed Cell adhesion
P39900 BXGT010148 Macrophage metalloelastase 4321 reviewed Enzyme
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P42574 BXGT010317 Caspase-3 836 reviewed Enzyme
P43354 BXGT010381 Nuclear receptor subfamily 4 group A member 2 4929 reviewed Nuclear receptor
P45983 BXGT010494 Mitogen-activated protein kinase 8 5599 reviewed Kinase
P46108 BXGT010509 Adapter molecule crk 1398 reviewed
P49137 BXGT010680 MAP kinase-activated protein kinase 2 9261 reviewed Kinase
P55040 BXGT011099 GTP-binding protein GEM 2669 reviewed
P55774 BXGT011124 C-C motif chemokine 18 6362 reviewed Signaling
P55899 BXGT011131 IgG receptor FcRn large subunit p51 2217 reviewed
P63244 BXGT011510 Receptor of activated protein C kinase 1 10399 reviewed
Q02487 BXGT012656 Desmocollin-2 1824 reviewed Cell adhesion
Q03518 BXGT012723 Antigen peptide transporter 1 6890 reviewed Transporter
Q07011 BXGT012912 Tumor necrosis factor receptor superfamily member 9 3604 reviewed
Q13155 BXGT013320 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 7965 reviewed
Q14126 BXGT013446 Desmoglein-2 1829 reviewed Cell adhesion
Q15063 BXGT013531 Periostin 10631 reviewed Signaling
Q15910 BXGT013612 Histone-lysine N-methyltransferase EZH2 2146 reviewed Epigenetic regulator
Q16539 BXGT013634 Mitogen-activated protein kinase 14 1432 reviewed Kinase
Q16874 BXGT013685 Cytochrome P450 21-hydroxylase 1589 unreviewed
Q5Y7D3 BXGT015912 HLA class II histocompatibility antigen DQ beta chain 3119 unreviewed
Q92769 BXGT019370 Histone deacetylase 2 3066 reviewed Epigenetic regulator
Q9BZS1 BXGT020203 Forkhead box protein P3 50943 reviewed
Q9H5I1 BXGT020480 Histone-lysine N-methyltransferase SUV39H2 79723 reviewed
Q9HC29 BXGT020526 Nucleotide-binding oligomerization domain-containing protein 2 64127 reviewed Enzyme
Q9Y2R2 BXGT022243 Tyrosine-protein phosphatase non-receptor type 22 26191 reviewed
P04439 BXGT022649 HLA class I histocompatibility antigen, A-3 alpha chain 3105 reviewed
Q16552 BXGT023419 Interleukin-17A 3605 reviewed
P11836 BXGT025994 B-lymphocyte antigen CD20 931 reviewed Receptor
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease