Showing entry for Complement C3


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT005719
Protein NameComplement C3
Uniport IdP01024
GeneC3
Gene Id718
DomainA2M; A2M_BRD; A2M_recep; ANATO; MG1; MG2; MG3; MG4; NTR; TED_complement
Pfam PF00207   PF07703   PF07677   PF01821   PF17790   PF01835   PF17791   PF17789   PF01759   PF07678  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.3 Signaling molecules and interaction hsa04080 Neuroactive ligand-receptor interaction
4. Cellular Processes 4.1 Transport and catabolism hsa04145 Phagosome
5. Organismal Systems 5.1 Immune system hsa04610 Complement and coagulation cascades
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05133 Pertussis
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05134 Legionellosis
6. Human Diseases 6.10 Infectious diseases: Parasitic hsa05140 Leishmaniasis
6. Human Diseases 6.10 Infectious diseases: Parasitic hsa05142 Chagas disease (American trypanosomiasis)
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05150 Staphylococcus aureus infection
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05152 Tuberculosis
6. Human Diseases 6.9 Infectious diseases: Viral hsa05167 Kaposi sarcoma-associated herpesvirus infection
6. Human Diseases 6.9 Infectious diseases: Viral hsa05168 Herpes simplex virus 1 infection
6. Human Diseases 6.1 Cancers: Overview hsa05203 Viral carcinogenesis
6. Human Diseases 6.3 Immune diseases hsa05322 Systemic lupus erythematosus
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0097242 amyloid-beta clearance
Biological Process GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling
Biological Process GO:0044267 cellular protein metabolic process
Biological Process GO:0006956 complement activation
Biological Process GO:0006957 complement activation, alternative pathway
Biological Process GO:0006958 complement activation, classical pathway
Biological Process GO:0097278 complement-dependent cytotoxicity
Biological Process GO:0150062 complement-mediated synapse pruning
Biological Process GO:0006631 fatty acid metabolic process
Biological Process GO:0007186 G protein-coupled receptor signaling pathway
Biological Process GO:0006955 immune response
Biological Process GO:0006954 inflammatory response
Biological Process GO:0016322 neuron remodeling
Biological Process GO:0043312 neutrophil degranulation
Biological Process GO:0001970 positive regulation of activation of membrane attack complex
Biological Process GO:0045766 positive regulation of angiogenesis
Biological Process GO:2000427 positive regulation of apoptotic cell clearance
Biological Process GO:0010828 positive regulation of glucose transmembrane transport
Biological Process GO:0045745 positive regulation of G protein-coupled receptor signaling pathway
Biological Process GO:0010884 positive regulation of lipid storage
Biological Process GO:0060100 positive regulation of phagocytosis, engulfment
Biological Process GO:0001934 positive regulation of protein phosphorylation
Biological Process GO:0048260 positive regulation of receptor-mediated endocytosis
Biological Process GO:0001798 positive regulation of type IIa hypersensitivity
Biological Process GO:0010575 positive regulation of vascular endothelial growth factor production
Biological Process GO:0043687 post-translational protein modification
Biological Process GO:0030449 regulation of complement activation
Biological Process GO:0050776 regulation of immune response
Biological Process GO:0010866 regulation of triglyceride biosynthetic process
Biological Process GO:0009617 response to bacterium
Biological Process GO:0007165 signal transduction
Biological Process GO:0150064 vertebrate eye-specific patterning
molecular function GO:0031715 C5L2 anaphylatoxin chemotactic receptor binding
molecular function GO:0004866 endopeptidase inhibitor activity
molecular function GO:0005102 signaling receptor binding
cellular component GO:0035578 azurophil granule lumen
cellular component GO:0072562 blood microparticle
cellular component GO:0009986 cell surface
cellular component GO:0005788 endoplasmic reticulum lumen
cellular component GO:0070062 extracellular exosome
cellular component GO:0005576 extracellular region
cellular component GO:0005615 extracellular space
cellular component GO:0005886 plasma membrane
cellular component GO:0032991 protein-containing complex
cellular component GO:0034774 secretory granule lumen
Reactome
Pathway Id Pathway Name
R-HSA-1280218 Adaptive Immune System
R-HSA-162582 Signal Transduction
R-HSA-1643685 Disease
R-HSA-166658 Complement cascade
R-HSA-166663 Initial triggering of complement
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-173736 Alternative complement activation
R-HSA-174577 Activation of C3 and C5
R-HSA-198933 Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
R-HSA-372790 Signaling by GPCR
R-HSA-373076 Class A/1 (Rhodopsin-like receptors)
R-HSA-375276 Peptide ligand-binding receptors
R-HSA-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
R-HSA-388396 GPCR downstream signalling
R-HSA-392499 Metabolism of proteins
R-HSA-418594 G alpha (i) signalling events
R-HSA-500792 GPCR ligand binding
R-HSA-5663205 Infectious disease
R-HSA-597592 Post-translational protein modification
R-HSA-6798695 Neutrophil degranulation
R-HSA-8957275 Post-translational protein phosphorylation
R-HSA-9658195 Leishmania infection
R-HSA-9660826 Purinergic signaling in leishmaniasis infection
R-HSA-9664424 Cell recruitment (pro-inflammatory response)
R-HSA-977606 Regulation of Complement cascade
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001175 BXGD000029 Acquired Immunodeficiency Syndrome Infections; Immune System Diseases
C0001430 BXGD000054 Adenoma Neoplasms
C0001857 BXGD000085 AIDS related complex Infections; Immune System Diseases
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002726 BXGD000125 Amyloidosis Nutritional and Metabolic Diseases
C0002736 BXGD000127 Amyotrophic Lateral Sclerosis Nutritional and Metabolic Diseases; Nervous System Diseases
C0002878 BXGD000137 Anemia, Hemolytic Hemic and Lymphatic Diseases
C0002893 BXGD000150 Refractory anemias Hemic and Lymphatic Diseases
C0003257 BXGD000189 Antibody Deficiency Syndrome Immune System Diseases
C0003460 BXGD000191 Anuria Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0003864 BXGD000231 Arthritis Musculoskeletal Diseases
C0003872 BXGD000235 Arthritis, Psoriatic Skin and Connective Tissue Diseases; Musculoskeletal Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0004114 BXGD000255 Astrocytoma Neoplasms
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0004610 BXGD000281 Bacteremia Pathological Conditions, Signs and Symptoms; Infections
C0004623 BXGD000282 Bacterial Infections Infections
C0005129 BXGD000304 Bernard-Soulier Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007097 BXGD000424 Carcinoma Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007222 BXGD000454 Cardiovascular Diseases Cardiovascular Diseases
C0007786 BXGD000486 Brain Ischemia Nervous System Diseases; Cardiovascular Diseases
C0007787 BXGD000487 Transient Ischemic Attack Nervous System Diseases; Cardiovascular Diseases
C0008149 BXGD000520 Chlamydia Infections Female Urogenital Diseases and Pregnancy Complications; Infections; Male Urogenital Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0009730 BXGD000625 Spinal meningocele Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0009952 BXGD000639 Febrile Convulsions Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0010054 BXGD000647 Coronary Arteriosclerosis Cardiovascular Diseases
C0010068 BXGD000648 Coronary heart disease Cardiovascular Diseases
C0010346 BXGD000664 Crohn Disease Digestive System Diseases
C0010674 BXGD000683 Cystic Fibrosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Respiratory Tract Diseases
C0011195 BXGD000702 Dejerine-Sottas Disease (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0011570 BXGD000729 Mental Depression Behavior and Behavior Mechanisms
C0011581 BXGD000733 Depressive disorder Mental Disorders
C0011615 BXGD000738 Dermatitis, Atopic Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Immune System Diseases
C0011649 BXGD000746 Dermoid Cyst Neoplasms
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011854 BXGD000753 Diabetes Mellitus, Insulin-Dependent Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011881 BXGD000760 Diabetic Nephropathy Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0011882 BXGD000761 Diabetic Neuropathies Nervous System Diseases; Endocrine System Diseases
C0011884 BXGD000762 Diabetic Retinopathy Eye Diseases; Endocrine System Diseases; Cardiovascular Diseases
C0013221 BXGD000804 Drug toxicity Chemically-Induced Disorders
C0014060 BXGD000882 Encephalitis, St. Louis Infections; Nervous System Diseases
C0014070 BXGD000887 Encephalomyelitis Infections; Nervous System Diseases
C0014072 BXGD000888 Experimental Autoimmune Encephalomyelitis Immune System Diseases; Nervous System Diseases
C0014175 BXGD000904 Endometriosis Female Urogenital Diseases and Pregnancy Complications
C0014556 BXGD000932 Epilepsy, Temporal Lobe Nervous System Diseases
C0015672 BXGD001011 Fatigue Pathological Conditions, Signs and Symptoms
C0016037 BXGD001035 Fibrodysplasia Ossificans Progressiva Musculoskeletal Diseases
C0017601 BXGD001125 Glaucoma Eye Diseases
C0017605 BXGD001126 Angle Closure Glaucoma Eye Diseases
C0017606 BXGD001127 Primary angle-closure glaucoma Eye Diseases
C0017658 BXGD001138 Glomerulonephritis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0017661 BXGD001139 IGA Glomerulonephritis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Immune System Diseases
C0017662 BXGD001140 Glomerulonephritis, Membranoproliferative Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Immune System Diseases
C0017665 BXGD001141 Membranous glomerulonephritis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Immune System Diseases
C0017921 BXGD001152 Glycogen storage disease type II Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0018133 BXGD001176 Graft-vs-Host Disease Immune System Diseases
C0018965 BXGD001258 Hematuria Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0019061 BXGD001273 Hemolytic-Uremic Syndrome Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Hemic and Lymphatic Diseases
C0019163 BXGD001295 Hepatitis B Digestive System Diseases; Infections
C0019193 BXGD001299 Hepatitis, Toxic Digestive System Diseases; Chemically-Induced Disorders
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0019348 BXGD001325 Herpes Simplex Infections Infections; Skin and Connective Tissue Diseases
C0020179 BXGD001363 Huntington Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders
C0020258 BXGD001371 Hydrocephalus, Normal Pressure Nervous System Diseases
C0020429 BXGD001378 Hyperalgesia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0020443 BXGD001385 Hypercholesterolemia Nutritional and Metabolic Diseases
C0020473 BXGD001396 Hyperlipidemia Nutritional and Metabolic Diseases
C0020474 BXGD001397 Hyperlipidemia, Familial Combined Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0020557 BXGD001432 Hypertriglyceridemia Nutritional and Metabolic Diseases
C0020615 BXGD001445 Hypoglycemia Nutritional and Metabolic Diseases
C0021051 BXGD001475 Immunologic Deficiency Syndromes Immune System Diseases
C0021359 BXGD001498 Infertility Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0021368 BXGD001502 Inflammation Pathological Conditions, Signs and Symptoms
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0021400 BXGD001504 Influenza Infections; Respiratory Tract Diseases
C0021655 BXGD001508 Insulin Resistance Nutritional and Metabolic Diseases
C0022104 BXGD001529 Irritable Bowel Syndrome Digestive System Diseases
C0022658 BXGD001570 Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0022660 BXGD001571 Kidney Failure, Acute Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0022661 BXGD001572 Kidney Failure, Chronic Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023418 BXGD001642 leukemia Neoplasms
C0023448 BXGD001649 Lymphoid leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023449 BXGD001650 Acute lymphocytic leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023452 BXGD001651 Childhood Acute Lymphoblastic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023530 BXGD001683 Leukopenia Hemic and Lymphatic Diseases
C0023903 BXGD001720 Liver neoplasms Digestive System Diseases; Neoplasms
C0024131 BXGD001736 Lupus Vulgaris Infections; Skin and Connective Tissue Diseases
C0024138 BXGD001738 Lupus Erythematosus, Discoid Skin and Connective Tissue Diseases
C0024141 BXGD001740 Lupus Erythematosus, Systemic Skin and Connective Tissue Diseases; Immune System Diseases
C0024143 BXGD001741 Lupus Nephritis Female Urogenital Diseases and Pregnancy Complications; Skin and Connective Tissue Diseases; Male Urogenital Diseases; Immune System Diseases
C0024312 BXGD001766 Lymphopenia Immune System Diseases; Hemic and Lymphatic Diseases
C0024530 BXGD001783 Malaria Infections
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0024790 BXGD001804 Paroxysmal nocturnal hemoglobinuria Hemic and Lymphatic Diseases
C0025149 BXGD001826 Medulloblastoma Neoplasms
C0025299 BXGD001857 Meningocele Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0025517 BXGD001875 Metabolic Diseases Nutritional and Metabolic Diseases
C0026269 BXGD001897 Mitral Valve Stenosis Cardiovascular Diseases
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027055 BXGD001964 Myocardial Reperfusion Injury Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027121 BXGD001973 Myositis Musculoskeletal Diseases; Nervous System Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027697 BXGD002022 Nephritis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0027726 BXGD002030 Nephrotic Syndrome Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0027947 BXGD002061 Neutropenia Hemic and Lymphatic Diseases
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0028840 BXGD002089 Ocular Hypertension Eye Diseases
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0029458 BXGD002158 Osteoporosis, Postmenopausal Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0030305 BXGD002206 Pancreatitis Digestive System Diseases
C0030524 BXGD002236 Paratuberculosis Infections; Animal Diseases
C0030805 BXGD002256 Bullous pemphigoid Skin and Connective Tissue Diseases; Immune System Diseases
C0030807 BXGD002257 Pemphigus Skin and Connective Tissue Diseases; Immune System Diseases
C0030809 BXGD002258 Pemphigus Vulgaris Skin and Connective Tissue Diseases; Immune System Diseases
C0031099 BXGD002282 Periodontitis Stomatognathic Diseases
C0032285 BXGD002344 Pneumonia Infections; Respiratory Tract Diseases
C0032460 BXGD002355 Polycystic Ovary Syndrome Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0032584 BXGD002363 polyps Pathological Conditions, Signs and Symptoms
C0032914 BXGD002379 Pre-Eclampsia Female Urogenital Diseases and Pregnancy Complications
C0033687 BXGD002415 Proteinuria Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0033860 BXGD002438 Psoriasis Skin and Connective Tissue Diseases
C0034067 BXGD002456 Pulmonary Emphysema Respiratory Tract Diseases
C0034069 BXGD002458 Pulmonary Fibrosis Respiratory Tract Diseases
C0034152 BXGD002467 Henoch-Schoenlein Purpura Pathological Conditions, Signs and Symptoms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0034155 BXGD002468 Purpura, Thrombotic Thrombocytopenic Pathological Conditions, Signs and Symptoms; Hemic and Lymphatic Diseases
C0035078 BXGD002505 Kidney Failure Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0035126 BXGD002509 Reperfusion Injury Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0035258 BXGD002523 Restless Legs Syndrome Nervous System Diseases; Mental Disorders
C0035304 BXGD002528 Retinal Degeneration Eye Diseases
C0035309 BXGD002530 Retinal Diseases Eye Diseases
C0035334 BXGD002539 Retinitis Pigmentosa Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0035344 BXGD002541 Retinopathy of Prematurity Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0035435 BXGD002549 Rheumatism Skin and Connective Tissue Diseases; Musculoskeletal Diseases
C0035455 BXGD002554 Rhinitis Infections; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0036646 BXGD002627 Age-related cataract Eye Diseases
C0038013 BXGD002725 Ankylosing spondylitis Musculoskeletal Diseases
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0038525 BXGD002768 Subarachnoid Hemorrhage Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0040034 BXGD002836 Thrombocytopenia Hemic and Lymphatic Diseases
C0040558 BXGD002873 Toxoplasmosis Infections
C0041234 BXGD002901 Chagas Disease Infections
C0041296 BXGD002903 Tuberculosis Infections
C0041755 BXGD002933 Adverse reaction to drug Chemically-Induced Disorders
C0042165 BXGD002966 Anterior uveitis Eye Diseases
C0042386 BXGD002980 Vasculitis, Hemorrhagic Pathological Conditions, Signs and Symptoms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0042769 BXGD002999 Virus Diseases Infections
C0043349 BXGD003044 Xerophthalmia Eye Diseases
C0085696 BXGD003244 Chronic prostatitis Male Urogenital Diseases
C0086445 BXGD003285 Idiopathic Membranous Glomerulonephritis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Immune System Diseases
C0086922 BXGD003314 Rheumatoid Purpura Pathological Conditions, Signs and Symptoms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0149516 BXGD003324 Chronic sinusitis Infections; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0149931 BXGD003388 Migraine Disorders Nervous System Diseases
C0149940 BXGD003391 Sciatic Neuropathy Nervous System Diseases
C0151517 BXGD003431 Complete atrioventricular block Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0151539 BXGD003435 Blood urea increased Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0151650 BXGD003454 Renal fibrosis Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0151744 BXGD003469 Myocardial Ischemia Cardiovascular Diseases
C0153092 BXGD003615 Mumps meningitis Infections; Nervous System Diseases; Stomatognathic Diseases
C0155626 BXGD003806 Acute myocardial infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0155862 BXGD003827 Streptococcal pneumonia Infections; Respiratory Tract Diseases
C0155877 BXGD003830 Allergic asthma Respiratory Tract Diseases; Immune System Diseases
C0156221 BXGD003842 Acute glomerulonephritis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0162871 BXGD003996 Aortic Aneurysm, Abdominal Cardiovascular Diseases
C0178664 BXGD004032 Glomerulosclerosis (disorder) Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Cardiovascular Diseases
C0202236 BXGD004086 Triglycerides measurement
C0206624 BXGD004190 Hepatoblastoma Neoplasms
C0221021 BXGD004368 Microangiopathic hemolytic anemia Hemic and Lymphatic Diseases
C0221238 BXGD004415 Mesangial proliferative glomerulonephritis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0221505 BXGD004466 Lesion of brain
C0231341 BXGD004492 Premature aging syndrome Pathological Conditions, Signs and Symptoms
C0233523 BXGD004586 Antisocial behavior Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0234985 BXGD004708 Mental deterioration Mental Disorders
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0235989 BXGD004801 Renal interstitial fibrosis Female Urogenital Diseases and Pregnancy Complications; Skin and Connective Tissue Diseases; Male Urogenital Diseases
C0238281 BXGD004902 Middle Cerebral Artery Syndrome Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0238463 BXGD004938 Papillary thyroid carcinoma Neoplasms; Endocrine System Diseases
C0242338 BXGD005149 HTLV Infections Infections; Immune System Diseases
C0242339 BXGD005150 Dyslipidemias Nutritional and Metabolic Diseases
C0242383 BXGD005160 Age related macular degeneration Eye Diseases
C0242461 BXGD005169 Purpura, Nonthrombocytopenic Pathological Conditions, Signs and Symptoms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0242488 BXGD005170 Acute Lung Injury Respiratory Tract Diseases
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0262988 BXGD005278 Vasculitis of the skin Skin and Connective Tissue Diseases; Cardiovascular Diseases
C0263313 BXGD005285 Pemphigus Foliaceus Skin and Connective Tissue Diseases; Immune System Diseases
C0264774 BXGD005427 Mitral and aortic incompetence Cardiovascular Diseases
C0268731 BXGD006029 Renal glomerular disease Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0268732 BXGD006030 Nephritic syndrome Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0268743 BXGD006033 Membranoproliferative Glomerulonephritis, Type II Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Immune System Diseases
C0270707 BXGD006086 Kluver-Bucy Syndrome Nervous System Diseases; Mental Disorders
C0271073 BXGD006157 Eales disease Pathological Conditions, Signs and Symptoms; Eye Diseases; Cardiovascular Diseases
C0271084 BXGD006159 Exudative age-related macular degeneration Eye Diseases
C0271650 BXGD006227 Impaired glucose tolerance Nutritional and Metabolic Diseases
C0272242 BXGD006330 Complement deficiency disease Immune System Diseases; Hemic and Lymphatic Diseases
C0278510 BXGD006526 Childhood Medulloblastoma Neoplasms
C0278876 BXGD006607 Adult Medulloblastoma Neoplasms
C0279628 BXGD006659 Adenocarcinoma Of Esophagus Digestive System Diseases; Neoplasms
C0281658 BXGD006778 Intraocular Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0301918 BXGD006829 Hypersensitivity reaction mediated by immune complex Immune System Diseases
C0338656 BXGD007211 Impaired cognition Mental Disorders
C0339573 BXGD007271 Glaucoma, Primary Open Angle Eye Diseases
C0343386 BXGD007620 Clostridium difficile infection Infections
C0344315 BXGD007666 Depressed mood Behavior and Behavior Mechanisms
C0345904 BXGD007745 Malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0345967 BXGD007756 Malignant mesothelioma Neoplasms; Respiratory Tract Diseases
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0374997 BXGD007967 Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site
C0376362 BXGD007994 Purpura Hemorrhagica Pathological Conditions, Signs and Symptoms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0398623 BXGD008202 Thrombophilia Hemic and Lymphatic Diseases
C0400966 BXGD008266 Non-alcoholic Fatty Liver Disease Digestive System Diseases
C0409974 BXGD008401 Lupus Erythematosus Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases; Immune System Diseases
C0442874 BXGD008814 Neuropathy Nervous System Diseases
C0472381 BXGD008910 Posterior Circulation Transient Ischemic Attack Nervous System Diseases; Cardiovascular Diseases
C0497156 BXGD009053 Lymphadenopathy Hemic and Lymphatic Diseases
C0520679 BXGD009101 Sleep Apnea, Obstructive Respiratory Tract Diseases; Nervous System Diseases
C0524620 BXGD009236 Metabolic Syndrome X Nutritional and Metabolic Diseases
C0524910 BXGD009248 Hepatitis C, Chronic Digestive System Diseases; Infections
C0543698 BXGD009292 Hypersensitive syndrome Immune System Diseases
C0553723 BXGD009416 Squamous cell carcinoma of skin Neoplasms; Skin and Connective Tissue Diseases
C0566602 BXGD009489 Primary sclerosing cholangitis Digestive System Diseases
C0577608 BXGD009532 C4 complement assay (procedure)
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0677607 BXGD009721 Hashimoto Disease Endocrine System Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0686377 BXGD009834 CNS metastases Neoplasms; Nervous System Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0687720 BXGD009844 Central Diabetes Insipidus Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0699949 BXGD009872 airway disease Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases
C0700225 BXGD009882 Serum creatinine raised Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0730285 BXGD009943 Diabetic macular edema Eye Diseases; Endocrine System Diseases; Cardiovascular Diseases
C0740376 BXGD009982 Middle Cerebral Artery Thrombosis Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0740391 BXGD009987 Middle Cerebral Artery Occlusion Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0740392 BXGD009988 Infarction, Middle Cerebral Artery Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0751019 BXGD010293 Carotid Circulation Transient Ischemic Attack Nervous System Diseases; Cardiovascular Diseases
C0751020 BXGD010294 Transient Ischemic Attack, Vertebrobasilar Circulation Nervous System Diseases; Cardiovascular Diseases
C0751021 BXGD010295 Crescendo Transient Ischemic Attacks Nervous System Diseases; Cardiovascular Diseases
C0751022 BXGD010296 Brain Stem Ischemia, Transient Nervous System Diseases; Cardiovascular Diseases
C0751606 BXGD010523 Adult Acute Lymphocytic Leukemia
C0751651 BXGD010539 Mitochondrial Diseases Nutritional and Metabolic Diseases
C0751845 BXGD010605 Middle Cerebral Artery Embolus Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0751846 BXGD010606 Left Middle Cerebral Artery Infarction Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0751847 BXGD010607 Embolic Infarction, Middle Cerebral Artery Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0751848 BXGD010608 Thrombotic Infarction, Middle Cerebral Artery Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0751849 BXGD010609 Right Middle Cerebral Artery Infarction Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0752335 BXGD010720 Neuropsychiatric Systemic Lupus Erythematosus Infections; Skin and Connective Tissue Diseases; Immune System Diseases; Nervous System Diseases; Cardiovascular Diseases
C0848548 BXGD010881 hypertensive nephropathy Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Cardiovascular Diseases
C0853888 BXGD010983 Hypocomplementaemia Hemic and Lymphatic Diseases
C0856825 BXGD011118 Acute GVH disease Immune System Diseases
C0860207 BXGD011220 Drug-Induced Liver Disease Digestive System Diseases; Chemically-Induced Disorders
C0876973 BXGD011322 Infectious Lung Disorder Infections; Respiratory Tract Diseases
C0878521 BXGD011367 Beta thalassemia trait Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0878544 BXGD011368 Cardiomyopathies Cardiovascular Diseases
C0917805 BXGD011414 Transient Cerebral Ischemia Nervous System Diseases; Cardiovascular Diseases
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0920350 BXGD011466 Autoimmune thyroiditis Immune System Diseases; Endocrine System Diseases
C0920563 BXGD011469 Insulin Sensitivity Nutritional and Metabolic Diseases
C0941057 BXGD011492 Ulcerative colitis, quiescent Digestive System Diseases
C0948242 BXGD011519 Nuchal bleb, familial Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Immune System Diseases; Hemic and Lymphatic Diseases
C0949664 BXGD011583 Tauopathies Nervous System Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1261470 BXGD011854 Congenital meningocele Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C1262760 BXGD011886 Hepatitis, Drug-Induced Digestive System Diseases; Chemically-Induced Disorders
C1269683 BXGD012001 Major Depressive Disorder Mental Disorders
C1269955 BXGD012005 Tumor Cell Invasion
C1270972 BXGD012006 Mild cognitive disorder Mental Disorders
C1292769 BXGD012230 Precursor B-cell lymphoblastic leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1319466 BXGD012417 Barber Say syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Stomatognathic Diseases
C1332655 BXGD012544 Complement component 3 deficiency
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C1400417 BXGD013013 Immune complex nephritis
C1504336 BXGD013137 Polypoidal choroidal vasculopathy
C1527335 BXGD013270 Transient Ischemic Attack, Anterior Circulation Nervous System Diseases; Cardiovascular Diseases
C1527336 BXGD013271 Sjogren's Syndrome Eye Diseases; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases; Stomatognathic Diseases
C1535939 BXGD013323 Pneumocystis jiroveci pneumonia Infections; Respiratory Tract Diseases
C1536085 BXGD013334 Geographic Atrophy Eye Diseases
C1561643 BXGD013363 Chronic Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1565489 BXGD013401 Renal Insufficiency Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1565662 BXGD013402 Acute Kidney Insufficiency Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1696708 BXGD013504 Prehypertension Cardiovascular Diseases
C1704231 BXGD013534 Metastatic Malignant Neoplasm to the Leptomeninges Nervous System Diseases
C1704378 BXGD013554 Heymann Nephritis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Immune System Diseases
C1704417 BXGD013557 Hyperlipoproteinemia Type IIb Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C1735608 BXGD013715 SLE flare
C1800706 BXGD013755 Idiopathic Pulmonary Fibrosis Respiratory Tract Diseases
C1837512 BXGD014243 Decreased serum complement C3
C1844383 BXGD014628 Recurrent bacterial infection Infections
C1848296 BXGD014918 DOSAGE-SENSITIVE SEX REVERSAL Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C1857941 BXGD015756 Brooke-Spiegler syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Skin and Connective Tissue Diseases
C1879828 BXGD016582 Benign Teratoma Neoplasms
C1956346 BXGD016627 Coronary Artery Disease Cardiovascular Diseases
C1961099 BXGD016672 Precursor T-Cell Lymphoblastic Leukemia-Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1961102 BXGD016673 Precursor Cell Lymphoblastic Leukemia Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1969372 BXGD016775 Tubulointerstitial fibrosis
C1969651 BXGD016785 Macular Degeneration, Age-Related, 9 Eye Diseases
C2237660 BXGD016962 exudative macular degeneration Eye Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2316810 BXGD017030 Chronic kidney disease stage 5 Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C2609282 BXGD017177 Reticular pseudodrusen
C2609414 BXGD017182 Acute kidney injury Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C2676033 BXGD017322 Hepatoblastoma Caused By Somatic Mutation Digestive System Diseases; Neoplasms
C2699419 BXGD017458 Complement C3 Measurement
C2711227 BXGD017478 Steatohepatitis Digestive System Diseases
C2717961 BXGD017519 Thrombotic Microangiopathies Hemic and Lymphatic Diseases
C2752037 BXGD017757 HEMOLYTIC UREMIC SYNDROME, ATYPICAL, SUSCEPTIBILITY TO, 5
C2931788 BXGD018064 Atypical Hemolytic Uremic Syndrome Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Hemic and Lymphatic Diseases
C2937358 BXGD018159 Cerebral Hemorrhage Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C2985280 BXGD018223 Blood Protein Measurement
C2986717 BXGD018241 Anti-N-Methyl-D-Aspartate Receptor Encephalitis Neoplasms; Immune System Diseases; Nervous System Diseases
C3151071 BXGD018385 COMPLEMENT COMPONENT 3 DEFICIENCY, AUTOSOMAL RECESSIVE Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Immune System Diseases
C3532239 BXGD019055 Mitochondrial cardiomyopathy
C3658248 BXGD019253 Hypertriglyceridemic Waist Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C3658290 BXGD019256 Drug-Induced Acute Liver Injury Digestive System Diseases; Chemically-Induced Disorders
C3854173 BXGD019824 Pre-renal acute kidney injury Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C3854222 BXGD019826 Human immunodeficiency virus (HIV) II infection category B1
C3888896 BXGD019990 Wet age-related macular degeneration
C4015286 BXGD020198 MACULAR DEGENERATION, EARLY-ONSET
C4015971 BXGD020253 MACULAR DEGENERATION, AGE-RELATED, 9, SUSCEPTIBILITY TO
C4049006 BXGD021912 Selective immunoglobulin A deficiency
C4055342 BXGD021999 C3 Glomerulonephritis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C4087273 BXGD022140 C3 glomerulopathy
C4275242 BXGD022371 Sudden sensorineural hearing loss Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C4277682 BXGD022376 Chemical and Drug Induced Liver Injury Digestive System Diseases; Chemically-Induced Disorders
C4279912 BXGD022378 Chemically-Induced Liver Toxicity Digestive System Diseases; Chemically-Induced Disorders
C4285910 BXGD022462 Obstructive sleep apnea hypopnea syndrome
C4290046 BXGD022507 trachomatis
C4529962 BXGD023178 Fatty Liver Disease
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0002586 Calcium 40.08
BXGC0002588 Magnesium 24.31
BXGC0002591 Potassium 39.1
BXGC0002616 Copper 63.55
BXGC0002682 Zinc 65.41
BXGC0002722 Nitrate 62
BXGC0003705 Chloride 35.45
BXGC0018397 beta-1,4-mannan 180.06
BXGC0037687 (4S)-2-methylpentane-2,4-diol 118.1
BXGC0050194 alpha-D-Mannose 180.06
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein