adisease

Showing entry for Sickle Cell Trait

General Disease Information
BXGD Id	BXGD002663
Disease Name	Sickle Cell Trait
Disease CUI Id	C0037054
MeSH Codes	C16 C15
Disease Class Name	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00767	BXGT003949	Acyl-CoA desaturase	6319	reviewed
O14746	BXGT004091	Telomerase reverse transcriptase	7015	reviewed	Enzyme
O14791	BXGT004101	Apolipoprotein L1	8542	reviewed	Transporter
O15553	BXGT004181	Pyrin	4210	reviewed
P00734	BXGT005630	Prothrombin	2147	reviewed	Enzyme
P01270	BXGT005746	Parathyroid hormone	5741	reviewed
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P02008	BXGT005832	Hemoglobin subunit zeta	3050	reviewed
P02042	BXGT005834	Hemoglobin subunit delta	3045	reviewed
P02649	BXGT005909	Apolipoprotein E	348	reviewed
P04040	BXGT006132	Catalase	847	reviewed	Enzyme
P05121	BXGT006320	Plasminogen activator inhibitor 1	5054	reviewed	Enzyme modulator
P05164	BXGT006333	Myeloperoxidase	4353	reviewed	Enzyme
P05231	BXGT006345	Interleukin-6	3569	reviewed
P06732	BXGT006489	Creatine kinase M-type	1158	reviewed	Kinase
P06753	BXGT006498	Tropomyosin alpha-3 chain	7170	reviewed	Cellular structure
P0DMV8	BXGT007509	Heat shock 70 kDa protein 1A	3304	reviewed
P0DMV9	BXGT007510	Heat shock 70 kDa protein 1B	3304	reviewed
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P11413	BXGT007701	Glucose-6-phosphate 1-dehydrogenase	2539	reviewed	Enzyme
P12318	BXGT007799	Low affinity immunoglobulin gamma Fc region receptor II-a	2212	reviewed	Cell adhesion
P12821	BXGT007849	Angiotensin-converting enzyme	1636	reviewed	Enzyme
P16442	BXGT008227	Histo-blood group ABO system transferase	28	reviewed	Enzyme
P16671	BXGT008255	Platelet glycoprotein 4	948	reviewed	Receptor
P18206	BXGT008389	Vinculin	7414	reviewed
P19320	BXGT008470	Vascular cell adhesion protein 1	7412	reviewed
P21583	BXGT008667	Kit ligand	4254	reviewed
P28066	BXGT009227	Proteasome subunit alpha type-5	5686	reviewed
P35228	BXGT009800	Nitric oxide synthase, inducible	4843	reviewed
P35579	BXGT009852	Myosin-9	4627	reviewed
P42898	BXGT010344	Methylenetetrahydrofolate reductase	4524	reviewed
P53985	BXGT011022	Monocarboxylate transporter 1	6566	reviewed	Transporter
P60709	BXGT011322	Actin, cytoplasmic 1	60	reviewed	Cellular structure
P68871	BXGT011615	Hemoglobin subunit beta	3043	reviewed
P69891	BXGT011646	Hemoglobin subunit gamma-1	3047	reviewed
P69892	BXGT011647	Hemoglobin subunit gamma-2	3048	reviewed
P69905	BXGT011649	Hemoglobin subunit alpha	3040	reviewed
P81172	BXGT011935	Hepcidin	57817	reviewed
Q15746	BXGT013591	Myosin light chain kinase, smooth muscle	4638	reviewed	Kinase
Q15750	BXGT013592	TGF-beta-activated kinase 1 and MAP3K7-binding protein 1	10454	reviewed	Kinase
Q30201	BXGT014297	Hereditary hemochromatosis protein	3077	reviewed
Q99250	BXGT019913	Sodium channel protein type 2 subunit alpha	6326	reviewed	Ion channel
Q9BV57	BXGT020140	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase	55256	reviewed	Enzyme
Q9UM73	BXGT021773	ALK tyrosine kinase receptor	238	reviewed	Kinase
P00738	BXGT022874	Haptoglobin	3240	reviewed	Enzyme
P31994	BXGT023298	Low affinity immunoglobulin gamma Fc region receptor II-b	2213	reviewed	Cell adhesion
Q16552	BXGT023419	Interleukin-17A	3605	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}