Showing entry for Hemoglobin subunit zeta


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT005832
Protein NameHemoglobin subunit zeta
Uniport IdP02008
GeneHBZ
Gene Id3050
DomainGlobin
Pfam PF00042  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0098869 cellular oxidant detoxification
Biological Process GO:0043249 erythrocyte maturation
Biological Process GO:0042744 hydrogen peroxide catabolic process
Biological Process GO:0000122 negative regulation of transcription by RNA polymerase II
molecular function GO:0020037 heme binding
molecular function GO:0005506 iron ion binding
molecular function GO:0043177 organic acid binding
molecular function GO:0019825 oxygen binding
molecular function GO:0005344 oxygen carrier activity
cellular component GO:0070062 extracellular exosome
cellular component GO:0031838 haptoglobin-hemoglobin complex
cellular component GO:0005833 hemoglobin complex
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002312 BXGD000107 alpha-Thalassemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0005283 BXGD000308 beta Thalassemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0005940 BXGD000352 Bone Diseases Musculoskeletal Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0014772 BXGD000948 Red Blood Cell Count measurement
C0019045 BXGD001269 Hemoglobinopathies Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0019348 BXGD001325 Herpes Simplex Infections Infections; Skin and Connective Tissue Diseases
C0020097 BXGD001360 HTLV-I Infections Infections; Immune System Diseases
C0023418 BXGD001642 leukemia Neoplasms
C0023440 BXGD001646 Acute Erythroblastic Leukemia Neoplasms; Hemic and Lymphatic Diseases
C0023492 BXGD001671 Leukemia, T-Cell Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023493 BXGD001672 Adult T-Cell Lymphoma/Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024299 BXGD001758 Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024314 BXGD001767 Lymphoproliferative Disorders Immune System Diseases; Hemic and Lymphatic Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0029453 BXGD002154 Osteopenia Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0030481 BXGD002228 Tropical Spastic Paraparesis Infections; Nervous System Diseases
C0037054 BXGD002663 Sickle Cell Trait Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0039730 BXGD002826 Thalassemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0158995 BXGD003917 Congenital anemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0200695 BXGD004046 Fetal hemoglobin determination
C0238790 BXGD004956 bone destruction
C0271980 BXGD006284 beta^0^ Thalassemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0272002 BXGD006292 alpha^0^ Thalassemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0472761 BXGD008916 Homozygous alpha thalassemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0524587 BXGD009232 Mean Corpuscular Volume (result)
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0598766 BXGD009669 Leukemogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C1261502 BXGD011856 Finding of Mean Corpuscular Hemoglobin
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1332206 BXGD012504 Adult Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332979 BXGD012571 Childhood Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1456873 BXGD013129 alpha^+^ Thalassemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C2347748 BXGD017041 Adult Erythroleukemia
C2985280 BXGD018223 Blood Protein Measurement
C3161174 BXGD018505 Hemoglobin H Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C3278365 BXGD018737 HEMOGLOBIN H HYDROPS FETALIS SYNDROME
C3841475 BXGD019800 beta^+^ Thalassemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C4520840 BXGD023041 Erythroleukemia (Erythroid/Myeloid) Neoplasms; Hemic and Lymphatic Diseases
C4528257 BXGD023159 Corpuscular Hemoglobin Concentration Mean
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0004275 Acetaldehyde 44.05
BXGC0008676 Haem 616.49
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein