adisease

Showing entry for MELAS Syndrome

General Disease Information
BXGD Id	BXGD003971
Disease Name	MELAS Syndrome
Disease CUI Id	C0162671
MeSH Codes	C16 C18 C05 C10 C14
Disease Class Name	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Musculoskeletal Diseases; Nervous System Diseases; Cardiovascular Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O15239	BXGT004139	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1	4694	reviewed
P00156	BXGT005469	Cytochrome b	4519	reviewed
P00441	BXGT005540	Superoxide dismutase [Cu-Zn]	6647	reviewed	Enzyme
P00491	BXGT005555	Purine nucleoside phosphorylase	4860	reviewed	Enzyme
P00846	BXGT005674	ATP synthase subunit a	4508	reviewed	Transporter
P01583	BXGT005771	Interleukin-1 alpha	3552	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P02462	BXGT005881	Collagen alpha-1(IV) chain	1282	reviewed
P03886	BXGT006108	NADH-ubiquinone oxidoreductase chain 1	4535	reviewed	Enzyme
P03897	BXGT006111	NADH-ubiquinone oxidoreductase chain 3	4537	reviewed
P03905	BXGT006113	NADH-ubiquinone oxidoreductase chain 4	4538	reviewed	Enzyme
P03915	BXGT006114	NADH-ubiquinone oxidoreductase chain 5	4540	reviewed	Enzyme
P03923	BXGT006115	NADH-ubiquinone oxidoreductase chain 6	4541	reviewed
P04179	BXGT006163	Superoxide dismutase [Mn], mitochondrial	6648	reviewed	Enzyme
P05937	BXGT006396	Calbindin	793	reviewed	Calcium-binding protein
P07202	BXGT006565	Thyroid peroxidase	7173	reviewed	Enzyme
P07477	BXGT006629	Trypsin-1	5644	reviewed	Enzyme
P08243	BXGT006755	Asparagine synthetase [glutamine-hydrolyzing]	440	reviewed	Enzyme
P12235	BXGT007774	ADP/ATP translocase 1	291	reviewed	Transporter
P20132	BXGT008546	L-serine dehydratase/L-threonine deaminase	10993	reviewed	Enzyme
P28331	BXGT009252	NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial	4719	reviewed	Enzyme
P36551	BXGT009927	Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial	1371	reviewed	Enzyme
P42345	BXGT010304	Serine/threonine-protein kinase mTOR	2475	reviewed	Kinase
P42684	BXGT010331	Tyrosine-protein kinase ABL2	27	reviewed	Kinase
P49821	BXGT010748	NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial	4723	reviewed
P50591	BXGT010814	Tumor necrosis factor ligand superfamily member 10	8743	reviewed	Signaling
P54098	BXGT011030	DNA polymerase subunit gamma-1	5428	reviewed	Enzyme
P60709	BXGT011322	Actin, cytoplasmic 1	60	reviewed	Cellular structure
Q00059	BXGT012512	Transcription factor A, mitochondrial	7019	reviewed
Q00796	BXGT012549	Sorbitol dehydrogenase	6652	reviewed	Enzyme
Q8NI60	BXGT018572	Atypical kinase COQ8A, mitochondrial	56997	reviewed	Kinase
Q99551	BXGT019933	Transcription termination factor 1, mitochondrial	7978	reviewed
Q9UBL9	BXGT021656	P2X purinoceptor 2	22953	reviewed	Ion channel
P00395	BXGT023596	Cytochrome c oxidase subunit 1	4512	reviewed	Enzyme
P07954	BXGT023939	Fumarate hydratase, mitochondrial	2271	reviewed	Enzyme
P00403	BXGT026137	Cytochrome c oxidase subunit 2	4513	reviewed	Enzyme

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}