protein

Showing entry for Cytochrome b

General Target Information
BXGT Id	BXGT005469
Protein Name	Cytochrome b
Uniport Id	P00156
Gene	MT-CYB
Gene Id	4519
Domain	Cytochrome_B; Cytochrom_B_C
Pfam	PF00032 PF00033
Organism	Homo sapiens (Human)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name
1. Metabolism	1.2 Energy metabolism	hsa00190	Oxidative phosphorylation
1. Metabolism	1.0 Global and overview maps	hsa01100	Metabolic pathways
5. Organismal Systems	5.3 Circulatory system	hsa04260	Cardiac muscle contraction
5. Organismal Systems	5.10 Environmental adaptation	hsa04714	Thermogenesis
6. Human Diseases	6.7 Endocrine and metabolic diseases	hsa04932	Non-alcoholic fatty liver disease (NAFLD)
6. Human Diseases	6.4 Neurodegenerative diseases	hsa05010	Alzheimer disease
6. Human Diseases	6.4 Neurodegenerative diseases	hsa05012	Parkinson disease
6. Human Diseases	6.4 Neurodegenerative diseases	hsa05016	Huntington disease

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0031100	animal organ regeneration
Biological Process	GO:0015990	electron transport coupled proton transport
Biological Process	GO:0042538	hyperosmotic salinity response
Biological Process	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c
Biological Process	GO:0046686	response to cadmium ion
Biological Process	GO:0051592	response to calcium ion
Biological Process	GO:0033590	response to cobalamin
Biological Process	GO:0046688	response to copper ion
Biological Process	GO:0042493	response to drug
Biological Process	GO:0045471	response to ethanol
Biological Process	GO:0033762	response to glucagon
Biological Process	GO:0009408	response to heat
Biological Process	GO:0055093	response to hyperoxia
Biological Process	GO:0001666	response to hypoxia
Biological Process	GO:0046689	response to mercury ion
Biological Process	GO:0009636	response to toxic substance
molecular function	GO:0046872	metal ion binding
molecular function	GO:0044877	protein-containing complex binding
molecular function	GO:0008121	ubiquinol-cytochrome-c reductase activity
cellular component	GO:0031305	integral component of mitochondrial inner membrane
cellular component	GO:0005743	mitochondrial inner membrane
cellular component	GO:0005750	mitochondrial respiratory chain complex III
cellular component	GO:0005739	mitochondrion

Reactome

Pathway Id	Pathway Name
R-HSA-1428517	The citric acid (TCA) cycle and respiratory electron transport
R-HSA-1430728	Metabolism
R-HSA-163200	Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
R-HSA-611105	Respiratory electron transport

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class
C0001125	BXGD000024	Acidosis, Lactic	Nutritional and Metabolic Diseases
C0001175	BXGD000029	Acquired Immunodeficiency Syndrome	Infections; Immune System Diseases
C0002395	BXGD000111	Alzheimer's Disease	Nervous System Diseases; Mental Disorders
C0002871	BXGD000132	Anemia	Hemic and Lymphatic Diseases
C0003811	BXGD000222	Cardiac Arrhythmia	Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0003850	BXGD000225	Arteriosclerosis	Cardiovascular Diseases
C0004134	BXGD000256	Ataxia	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0004153	BXGD000260	Atherosclerosis	Cardiovascular Diseases
C0005684	BXGD000319	Malignant neoplasm of urinary bladder	Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005695	BXGD000323	Bladder Neoplasm	Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0006142	BXGD000374	Malignant neoplasm of breast	Neoplasms; Skin and Connective Tissue Diseases
C0006826	BXGD000408	Malignant Neoplasms	Neoplasms
C0006840	BXGD000409	Candidiasis	Infections
C0006849	BXGD000413	Oral candidiasis	Infections; Stomatognathic Diseases
C0007194	BXGD000452	Hypertrophic Cardiomyopathy	Cardiovascular Diseases
C0007222	BXGD000454	Cardiovascular Diseases	Cardiovascular Diseases
C0009324	BXGD000597	Ulcerative Colitis	Digestive System Diseases
C0009402	BXGD000605	Colorectal Carcinoma	Digestive System Diseases; Neoplasms
C0010709	BXGD000689	Cyst	Pathological Conditions, Signs and Symptoms; Neoplasms
C0011603	BXGD000734	Dermatitis	Skin and Connective Tissue Diseases
C0011847	BXGD000749	Diabetes	Endocrine System Diseases
C0011849	BXGD000751	Diabetes Mellitus	Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011853	BXGD000752	Diabetes Mellitus, Experimental	Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011854	BXGD000753	Diabetes Mellitus, Insulin-Dependent	Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0011860	BXGD000755	Diabetes Mellitus, Non-Insulin-Dependent	Nutritional and Metabolic Diseases; Endocrine System Diseases
C0013421	BXGD000837	Dystonia	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0013502	BXGD000848	Echinococcosis	Infections
C0014544	BXGD000926	Epilepsy	Nervous System Diseases
C0014859	BXGD000961	Esophageal Neoplasms	Digestive System Diseases; Neoplasms
C0016053	BXGD001041	Fibromyalgia	Musculoskeletal Diseases; Nervous System Diseases
C0017601	BXGD001125	Glaucoma	Eye Diseases
C0018203	BXGD001184	Chronic granulomatous disease	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Immune System Diseases; Hemic and Lymphatic Diseases
C0018802	BXGD001227	Congestive heart failure	Cardiovascular Diseases
C0018916	BXGD001245	Hemangioma	Neoplasms
C0018979	BXGD001260	Hemianopsia	Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0018989	BXGD001263	Hemiparesis	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0019158	BXGD001293	Hepatitis	Digestive System Diseases
C0019159	BXGD001294	Hepatitis A	Digestive System Diseases; Infections
C0020179	BXGD001363	Huntington Disease	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders
C0020538	BXGD001422	Hypertensive disease	Cardiovascular Diseases
C0022541	BXGD001550	Kearns-Sayre syndrome	Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases; Eye Diseases; Musculoskeletal Diseases; Nervous System Diseases; Cardiovascular Diseases
C0023264	BXGD001625	Leigh Disease	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0023281	BXGD001628	Leishmaniasis	Infections; Skin and Connective Tissue Diseases
C0023283	BXGD001629	Leishmaniasis, Cutaneous	Infections; Skin and Connective Tissue Diseases
C0023290	BXGD001631	Leishmaniasis, Visceral	Infections
C0023418	BXGD001642	leukemia	Neoplasms
C0023893	BXGD001716	Liver Cirrhosis, Experimental	Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0024530	BXGD001783	Malaria	Infections
C0024623	BXGD001791	Malignant neoplasm of stomach	Digestive System Diseases; Neoplasms
C0025202	BXGD001832	melanoma	Neoplasms
C0025309	BXGD001860	Meningoencephalitis	Infections; Nervous System Diseases
C0025362	BXGD001866	Mental Retardation	Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0026769	BXGD001930	Multiple Sclerosis	Immune System Diseases; Nervous System Diseases
C0026848	BXGD001941	Myopathy	Musculoskeletal Diseases; Nervous System Diseases
C0027651	BXGD002009	Neoplasms	Neoplasms
C0027868	BXGD002053	Neuromuscular Diseases	Nervous System Diseases
C0028754	BXGD002082	Obesity	Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0028756	BXGD002083	Obesity, Morbid	Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0029089	BXGD002107	Ophthalmoplegia	Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0029124	BXGD002113	Optic Atrophy	Eye Diseases; Nervous System Diseases
C0029132	BXGD002117	Disorder of the optic nerve	Eye Diseases; Nervous System Diseases
C0030305	BXGD002206	Pancreatitis	Digestive System Diseases
C0030567	BXGD002240	Parkinson Disease	Nervous System Diseases
C0030757	BXGD002251	Pediculus capitis infestation	Infections; Skin and Connective Tissue Diseases
C0031117	BXGD002285	Peripheral Neuropathy	Nervous System Diseases
C0032285	BXGD002344	Pneumonia	Infections; Respiratory Tract Diseases
C0032897	BXGD002378	Prader-Willi Syndrome	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0032915	BXGD002380	Preexcitation Syndrome	Cardiovascular Diseases
C0033626	BXGD002412	Protein Deficiency	Nutritional and Metabolic Diseases
C0035126	BXGD002509	Reperfusion Injury	Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0035334	BXGD002539	Retinitis Pigmentosa	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0040156	BXGD002849	Thyrotoxicosis	Endocrine System Diseases
C0041227	BXGD002899	Trypanosomiasis	Infections
C0041234	BXGD002901	Chagas Disease	Infections
C0043202	BXGD003037	Wolff-Parkinson-White Syndrome	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0085584	BXGD003195	Encephalopathies	Nervous System Diseases
C0085593	BXGD003196	Chills	Pathological Conditions, Signs and Symptoms
C0149721	BXGD003349	Left Ventricular Hypertrophy	Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0149931	BXGD003388	Migraine Disorders	Nervous System Diseases
C0152018	BXGD003518	Esophageal carcinoma	Digestive System Diseases; Neoplasms
C0152025	BXGD003521	Polyneuropathy	Nervous System Diseases
C0152191	BXGD003556	Scotoma, Central	Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0154835	BXGD003748	Retinal telangiectasia	Cardiovascular Diseases
C0162666	BXGD003967	Mitochondrial Encephalomyopathies	Nutritional and Metabolic Diseases; Musculoskeletal Diseases; Nervous System Diseases
C0162670	BXGD003970	Mitochondrial Myopathies	Nutritional and Metabolic Diseases; Musculoskeletal Diseases; Nervous System Diseases
C0162671	BXGD003971	MELAS Syndrome	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Musculoskeletal Diseases; Nervous System Diseases; Cardiovascular Diseases
C0162674	BXGD003973	Chronic progressive external ophthalmoplegia	Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases; Eye Diseases; Musculoskeletal Diseases; Nervous System Diseases
C0234378	BXGD004661	Static Tremor	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0242422	BXGD005163	Parkinsonian Disorders	Nervous System Diseases
C0242698	BXGD005189	Ventricular Dysfunction, Left	Cardiovascular Diseases
C0242706	BXGD005191	Hyperoxia	Pathological Conditions, Signs and Symptoms
C0243026	BXGD005210	Sepsis	Pathological Conditions, Signs and Symptoms; Infections
C0262361	BXGD005229	Growth abnormality
C0268542	BXGD005977	Ornithine carbamoyltransferase deficiency	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0268596	BXGD006000	Multiple Acyl Coenzyme A Dehydrogenase Deficiency	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0270824	BXGD006113	Visual seizure	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0271196	BXGD006171	Scotoma, Centrocecal	Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0272220	BXGD006326	Chronic granulomatous disease, type II	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Immune System Diseases; Hemic and Lymphatic Diseases
C0338437	BXGD007174	Neurocysticercosis	Infections; Nervous System Diseases
C0338503	BXGD007193	Septo-Optic Dysplasia	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0342778	BXGD007548	Ubiquinone dehydrogenase deficiency
C0344232	BXGD007659	Blurred vision	Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0345319	BXGD007726	Cyst of hydatid of Morgagni	Pathological Conditions, Signs and Symptoms; Neoplasms
C0403823	BXGD008315	Asthenozoospermia	Male Urogenital Diseases
C0410000	BXGD008406	Overlap syndrome	Skin and Connective Tissue Diseases; Immune System Diseases
C0424551	BXGD008533	Impaired exercise tolerance
C0431128	BXGD008664	Papillary craniopharyngioma	Neoplasms
C0452138	BXGD008831	Sensorineural hearing loss, bilateral	Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0494475	BXGD009030	Tonic - clonic seizures	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0497327	BXGD009061	Dementia	Nervous System Diseases; Mental Disorders
C0524620	BXGD009236	Metabolic Syndrome X	Nutritional and Metabolic Diseases
C0546837	BXGD009343	Malignant neoplasm of esophagus	Digestive System Diseases; Neoplasms
C0559106	BXGD009465	Ventricular preexcitation	Pathological Conditions, Signs and Symptoms
C0596263	BXGD009639	Carcinogenesis	Pathological Conditions, Signs and Symptoms; Neoplasms
C0677886	BXGD009734	Epithelial ovarian cancer	Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0679427	BXGD009777	myeloblastosis	Pathological Conditions, Signs and Symptoms; Hemic and Lymphatic Diseases
C0699791	BXGD009867	Stomach Carcinoma	Digestive System Diseases; Neoplasms
C0699885	BXGD009869	Carcinoma of bladder	Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0751651	BXGD010539	Mitochondrial Diseases	Nutritional and Metabolic Diseases
C0851886	BXGD010929	Pneumocystis Infections	Infections
C0878544	BXGD011368	Cardiomyopathies	Cardiovascular Diseases
C0917796	BXGD011408	Optic Atrophy, Hereditary, Leber	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Eye Diseases; Nervous System Diseases
C0919267	BXGD011426	ovarian neoplasm	Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0948008	BXGD011499	Ischemic stroke	Nervous System Diseases; Cardiovascular Diseases
C0948444	BXGD011539	Mitochondrial DNA mutation
C1168401	BXGD011792	Squamous cell carcinoma of the head and neck	Neoplasms
C1290884	BXGD012198	Inflammatory disorder	Pathological Conditions, Signs and Symptoms
C1306459	BXGD012361	Primary malignant neoplasm	Neoplasms
C1332977	BXGD012569	Childhood Leukemia	Neoplasms
C1449563	BXGD013086	Cardiomyopathy, Familial Idiopathic	Cardiovascular Diseases
C1535939	BXGD013323	Pneumocystis jiroveci pneumonia	Infections; Respiratory Tract Diseases
C1557375	BXGD013360	Blurred Vision, CTCAE
C1708371	BXGD013600	Histiocytoid Cardiomyopathy	Cardiovascular Diseases
C1838993	BXGD014351	Episodic vomiting	Pathological Conditions, Signs and Symptoms
C1842937	BXGD014546	AURAL ATRESIA, CONGENITAL	Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C1843156	BXGD014561	Progressive sensorineural hearing impairment	Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C1844376	BXGD014627	Granulomatous Disease, Chronic, X-Linked	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Immune System Diseases; Hemic and Lymphatic Diseases
C1852372	BXGD015275	MITOCHONDRIAL COMPLEX III DEFICIENCY (disorder)	Nutritional and Metabolic Diseases
C1853141	BXGD015307	Slow decrease in visual acuity
C1857287	BXGD015692	Stroke-like episode	Nervous System Diseases; Cardiovascular Diseases
C1860475	BXGD015985	Retinal vascular tortuosity
C1861403	BXGD016045	Variable expressivity
C1863999	BXGD016208	Peroxisome Biogenesis Disorder, Complementation Group D	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C1956346	BXGD016627	Coronary Artery Disease	Cardiovascular Diseases
C2239176	BXGD016965	Liver carcinoma	Digestive System Diseases; Neoplasms
C2362324	BXGD017091	Pediatric Obesity	Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C2751582	BXGD017726	Mitochondrial respiratory chain defects
C2930619	BXGD017890	Sex Differentiation Disorders	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C3151898	BXGD018454	MITOCHONDRIAL MYOPATHY, INFANTILE, TRANSIENT
C3275417	BXGD018663	Ragged-red muscle fibers
C3539878	BXGD019087	Triple Negative Breast Neoplasms	Neoplasms; Skin and Connective Tissue Diseases
C3661525	BXGD019266	Autosomal Recessive Chronic Granulomatous Disease	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Immune System Diseases; Hemic and Lymphatic Diseases
C3665346	BXGD019278	Unspecified visual loss	Pathological Conditions, Signs and Symptoms; Eye Diseases
C3665347	BXGD019279	Visual Impairment	Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C3665386	BXGD019284	Abnormal vision	Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C3714756	BXGD019429	Intellectual Disability	Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C3810365	BXGD019652	Central visual impairment	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C4016600	BXGD020347	PARKINSONISM/MELAS OVERLAP SYNDROME
C4021569	BXGD020677	Central retinal vessel vascular tortuosity
C4048268	BXGD021896	Cortical visual impairment	Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C4551472	BXGD023303	Hypertrophic obstructive cardiomyopathy	Cardiovascular Diseases
C4553297	BXGD023538	Cystic Echinocccosis	Infections
C4721453	BXGD023744	Peripheral Nervous System Diseases	Nervous System Diseases
C4721610	BXGD023760	Carcinoma, Ovarian Epithelial	Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C4722518	BXGD023806	Triple-Negative Breast Carcinoma	Neoplasms; Skin and Connective Tissue Diseases
C4732730	BXGD023895	Blood spots

Target protein-related compounds

Compounds

BXGC Id	Compound Name	Strcuture	Molecular Weight
BXGC0008676	Haem		616.49

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}