adisease

Showing entry for Dysplastic Nevus

General Disease Information
BXGD Id	BXGD004117
Disease Name	Dysplastic Nevus
Disease CUI Id	C0205748
MeSH Codes	C16 C04
Disease Class Name	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms
Semantic Type	Neoplastic Process
Human Phenotype Ontology Id	HP:0001574
Human Phenotype Ontology Term	Abnormality of the integument
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O14746	BXGT004091	Telomerase reverse transcriptase	7015	reviewed	Enzyme
P00533	BXGT005575	Epidermal growth factor receptor	1956	reviewed	Kinase
P01111	BXGT005731	GTPase NRas	4893	reviewed	Enzyme modulator
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P01889	BXGT005809	HLA class I histocompatibility antigen, B-7 alpha chain	3106	reviewed
P02649	BXGT005909	Apolipoprotein E	348	reviewed
P03956	BXGT006120	Interstitial collagenase	4312	reviewed	Enzyme
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P05109	BXGT006318	Protein S100-A8	6279	reviewed	Calcium-binding protein
P06730	BXGT006487	Eukaryotic translation initiation factor 4E	1977	reviewed	Nucleic acid binding
P07339	BXGT006604	Cathepsin D	1509	reviewed	Enzyme
P08253	BXGT006757	72 kDa type IV collagenase	4313	reviewed	Enzyme
P09382	BXGT006882	Galectin-1	3956	reviewed	Signaling
P09488	BXGT006899	Glutathione S-transferase Mu 1	2944	reviewed
P10275	BXGT007552	Androgen receptor	367	reviewed	Nuclear receptor
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P11802	BXGT007750	Cyclin-dependent kinase 4	1019	reviewed	Kinase
P14174	BXGT007991	Macrophage migration inhibitory factor	4282	reviewed
P14921	BXGT008068	Protein C-ets-1	2113	reviewed	Transcription factor
P15056	BXGT008075	Serine/threonine-protein kinase B-raf	673	reviewed	Kinase
P15531	BXGT008136	Nucleoside diphosphate kinase A	4830	reviewed	Kinase
P17931	BXGT008356	Galectin-3	3958	reviewed	Signaling
P18887	BXGT008437	DNA repair protein XRCC1	7515	reviewed
P19021	BXGT008449	Peptidyl-glycine alpha-amidating monooxygenase	5066	reviewed	Enzyme
P22897	BXGT008816	Macrophage mannose receptor 1	4360	reviewed
P24385	BXGT008965	G1/S-specific cyclin-D1	595	reviewed	Enzyme modulator
P24530	BXGT008975	Endothelin receptor type B	1910	reviewed	G-protein coupled receptor
P26368	BXGT009106	Splicing factor U2AF 65 kDa subunit	11338	reviewed
P27540	BXGT009190	Aryl hydrocarbon receptor nuclear translocator	405	reviewed	Transcription factor
P28482	BXGT009263	Mitogen-activated protein kinase 1	5594	reviewed	Kinase
P29017	BXGT009305	T-cell surface glycoprotein CD1c	911	reviewed
P29323	BXGT009334	Ephrin type-B receptor 2	2048	reviewed	Kinase
P30281	BXGT009416	G1/S-specific cyclin-D3	896	reviewed	Enzyme modulator
P30711	BXGT009460	Glutathione S-transferase theta-1	2952	reviewed
P31151	BXGT009510	Protein S100-A7	6278	reviewed	Calcium-binding protein
P38398	BXGT010037	Breast cancer type 1 susceptibility protein	672	reviewed	Enzyme
P40692	BXGT010195	DNA mismatch repair protein Mlh1	4292	reviewed	Nucleic acid binding
P40763	BXGT010202	Signal transducer and activator of transcription 3	6774	reviewed	Nucleic acid binding
P40967	BXGT010212	Melanocyte protein PMEL	6490	reviewed	Signaling
P43246	BXGT010371	DNA mismatch repair protein Msh2	4436	reviewed	Nucleic acid binding
P45452	BXGT010462	Collagenase 3	4322	reviewed	Enzyme
P49747	BXGT010732	Cartilage oligomeric matrix protein	1311	reviewed
P51452	BXGT010849	Dual specificity protein phosphatase 3	1845	reviewed
P58004	BXGT011222	Sestrin-2	83667	reviewed	Enzyme
P61978	BXGT011399	Heterogeneous nuclear ribonucleoprotein K	3190	reviewed	Enzyme
Q00534	BXGT012533	Cyclin-dependent kinase 6	1021	reviewed	Kinase
Q00987	BXGT012559	E3 ubiquitin-protein ligase Mdm2	4193	reviewed	Nucleic acid binding
Q01726	BXGT012610	Melanocyte-stimulating hormone receptor	4157	reviewed	G-protein coupled receptor
Q13526	BXGT013369	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	5300	reviewed
Q14116	BXGT013442	Interleukin-18	3606	reviewed
Q14749	BXGT013503	Glycine N-methyltransferase	27232	reviewed
Q15554	BXGT013577	Telomeric repeat-binding factor 2	7014	reviewed
Q16658	BXGT013651	Fascin	6624	reviewed	Cellular structure
Q92993	BXGT019403	Histone acetyltransferase KAT5	10524	reviewed
Q9BXH1	BXGT020167	Bcl-2-binding component 3	27113	reviewed
Q9GZX6	BXGT020428	Interleukin-22	50616	reviewed
Q9HCU9	BXGT020539	Breast cancer metastasis-suppressor 1	25855	reviewed
Q9UNL4	BXGT021790	Inhibitor of growth protein 4	51147	reviewed	Nucleic acid binding
Q9UQD0	BXGT021811	Sodium channel protein type 8 subunit alpha	6334	reviewed	Ion channel

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}