Showing entry for Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT013369
Protein NamePeptidyl-prolyl cis-trans isomerase NIMA-interacting 1
Uniport IdQ13526
GenePIN1
Gene Id5300
DomainRotamase; WW
Pfam PF00639   PF00397  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
5. Organismal Systems 5.1 Immune system hsa04622 RIG-I-like receptor signaling pathway
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007049 cell cycle
Biological Process GO:1902430 negative regulation of amyloid-beta formation
Biological Process GO:2000146 negative regulation of cell motility
Biological Process GO:0070373 negative regulation of ERK1 and ERK2 cascade
Biological Process GO:0043524 negative regulation of neuron apoptotic process
Biological Process GO:0032091 negative regulation of protein binding
Biological Process GO:0042177 negative regulation of protein catabolic process
Biological Process GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway
Biological Process GO:0032480 negative regulation of type I interferon production
Biological Process GO:0030182 neuron differentiation
Biological Process GO:0090263 positive regulation of canonical Wnt signaling pathway
Biological Process GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development
Biological Process GO:0043547 positive regulation of GTPase activity
Biological Process GO:0043525 positive regulation of neuron apoptotic process
Biological Process GO:0032092 positive regulation of protein binding
Biological Process GO:0035307 positive regulation of protein dephosphorylation
Biological Process GO:0001934 positive regulation of protein phosphorylation
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:0051443 positive regulation of ubiquitin-protein transferase activity
Biological Process GO:0000413 protein peptidyl-prolyl isomerization
Biological Process GO:0050821 protein stabilization
Biological Process GO:0032465 regulation of cytokinesis
Biological Process GO:0010468 regulation of gene expression
Biological Process GO:0007088 regulation of mitotic nuclear division
Biological Process GO:0060393 regulation of pathway-restricted SMAD protein phosphorylation
Biological Process GO:1900180 regulation of protein localization to nucleus
Biological Process GO:0001932 regulation of protein phosphorylation
Biological Process GO:0031647 regulation of protein stability
Biological Process GO:1901796 regulation of signal transduction by p53 class mediator
Biological Process GO:0001666 response to hypoxia
Biological Process GO:0050808 synapse organization
molecular function GO:0008013 beta-catenin binding
molecular function GO:0016859 cis-trans isomerase activity
molecular function GO:0032794 GTPase activating protein binding
molecular function GO:0031434 mitogen-activated protein kinase kinase binding
molecular function GO:0003774 motor activity
molecular function GO:0003755 peptidyl-prolyl cis-trans isomerase activity
molecular function GO:0051219 phosphoprotein binding
molecular function GO:0050815 phosphoserine residue binding
molecular function GO:0050816 phosphothreonine residue binding
molecular function GO:0048156 tau protein binding
cellular component GO:0036064 ciliary basal body
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0030496 midbody
cellular component GO:0005739 mitochondrion
cellular component GO:0043005 neuron projection
cellular component GO:0016607 nuclear speck
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
R-HSA-1169408 ISG15 antiviral mechanism
R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes
R-HSA-1280215 Cytokine Signaling in Immune system
R-HSA-162582 Signal Transduction
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta
R-HSA-194315 Signaling by Rho GTPases
R-HSA-195258 RHO GTPase Effectors
R-HSA-212436 Generic Transcription Pathway
R-HSA-3700989 Transcriptional Regulation by TP53
R-HSA-5633007 Regulation of TP53 Activity
R-HSA-5668599 RHO GTPases Activate NADPH Oxidases
R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation
R-HSA-6804758 Regulation of TP53 Activity through Acetylation
R-HSA-6811555 PI5P Regulates TP53 Acetylation
R-HSA-73857 RNA Polymerase II Transcription
R-HSA-74160 Gene expression (Transcription)
R-HSA-913531 Interferon Signaling
R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000768 BXGD000007 Congenital Abnormality Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0001175 BXGD000029 Acquired Immunodeficiency Syndrome Infections; Immune System Diseases
C0001193 BXGD000030 Apert syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0001623 BXGD000066 Adrenal gland hypofunction Endocrine System Diseases
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002726 BXGD000125 Amyloidosis Nutritional and Metabolic Diseases
C0002736 BXGD000127 Amyotrophic Lateral Sclerosis Nutritional and Metabolic Diseases; Nervous System Diseases
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0005940 BXGD000352 Bone Diseases Musculoskeletal Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007134 BXGD000443 Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0007222 BXGD000454 Cardiovascular Diseases Cardiovascular Diseases
C0007847 BXGD000492 Malignant tumor of cervix Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0008928 BXGD000576 Cleidocranial Dysplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0009404 BXGD000606 Colorectal Neoplasms Digestive System Diseases; Neoplasms
C0009663 BXGD000618 Condylomata Acuminata Infections; Skin and Connective Tissue Diseases
C0010278 BXGD000660 Craniosynostosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0010606 BXGD000677 Adenoid Cystic Carcinoma Neoplasms
C0011265 BXGD000708 Presenile dementia Nervous System Diseases; Mental Disorders
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011881 BXGD000760 Diabetic Nephropathy Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0014859 BXGD000961 Esophageal Neoplasms Digestive System Diseases; Neoplasms
C0015625 BXGD001006 Fanconi Anemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Hemic and Lymphatic Diseases
C0015695 BXGD001013 Fatty Liver Digestive System Diseases
C0016057 BXGD001042 Fibrosarcoma Neoplasms
C0017636 BXGD001131 Glioblastoma Neoplasms
C0017638 BXGD001132 Glioma Neoplasms
C0018129 BXGD001175 Graft Rejection
C0018801 BXGD001226 Heart failure Cardiovascular Diseases
C0018802 BXGD001227 Congestive heart failure Cardiovascular Diseases
C0019163 BXGD001295 Hepatitis B Digestive System Diseases; Infections
C0020179 BXGD001363 Huntington Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders
C0020456 BXGD001392 Hyperglycemia Nutritional and Metabolic Diseases
C0020503 BXGD001411 Hyperparathyroidism, Secondary Endocrine System Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0021051 BXGD001475 Immunologic Deficiency Syndromes Immune System Diseases
C0023418 BXGD001642 leukemia Neoplasms
C0023465 BXGD001656 Acute monocytic leukemia Neoplasms
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0023487 BXGD001669 Acute Promyelocytic Leukemia Neoplasms
C0023492 BXGD001671 Leukemia, T-Cell Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023493 BXGD001672 Adult T-Cell Lymphoma/Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023524 BXGD001681 Leukoencephalopathy, Progressive Multifocal Infections; Nervous System Diseases
C0023890 BXGD001713 Liver Cirrhosis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0024141 BXGD001740 Lupus Erythematosus, Systemic Skin and Connective Tissue Diseases; Immune System Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0024668 BXGD001795 Mammary Neoplasms, Experimental Neoplasms
C0025149 BXGD001826 Medulloblastoma Neoplasms
C0025202 BXGD001832 melanoma Neoplasms
C0025517 BXGD001875 Metabolic Diseases Nutritional and Metabolic Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0031090 BXGD002280 Periodontal Diseases Stomatognathic Diseases
C0031099 BXGD002282 Periodontitis Stomatognathic Diseases
C0033578 BXGD002408 Prostatic Neoplasms Neoplasms; Male Urogenital Diseases
C0034068 BXGD002457 Pulmonary Eosinophilia Respiratory Tract Diseases; Hemic and Lymphatic Diseases
C0034069 BXGD002458 Pulmonary Fibrosis Respiratory Tract Diseases
C0036220 BXGD002587 Kaposi Sarcoma Neoplasms; Infections
C0036690 BXGD002632 Septicemia Pathological Conditions, Signs and Symptoms; Infections
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0038868 BXGD002781 Progressive supranuclear palsy Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0039538 BXGD002819 Teratoma Neoplasms
C0040136 BXGD002845 Thyroid Neoplasm Neoplasms; Endocrine System Diseases
C0042373 BXGD002978 Vascular Diseases Cardiovascular Diseases
C0042769 BXGD002999 Virus Diseases Infections
C0042834 BXGD003004 Vital capacity
C0085084 BXGD003121 Motor Neuron Disease Nervous System Diseases
C0151517 BXGD003431 Complete atrioventricular block Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0151779 BXGD003473 Cutaneous Melanoma Neoplasms; Skin and Connective Tissue Diseases
C0152013 BXGD003516 Adenocarcinoma of lung (disorder) Neoplasms
C0152018 BXGD003518 Esophageal carcinoma Digestive System Diseases; Neoplasms
C0153381 BXGD003626 Malignant neoplasm of mouth Neoplasms; Stomatognathic Diseases
C0153452 BXGD003647 Malignant neoplasm of gallbladder Digestive System Diseases; Neoplasms
C0153676 BXGD003679 Secondary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0162429 BXGD003942 Malnutrition Nutritional and Metabolic Diseases
C0162534 BXGD003953 Prion Diseases Infections; Nervous System Diseases
C0162871 BXGD003996 Aortic Aneurysm, Abdominal Cardiovascular Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0205647 BXGD004099 Follicular adenoma Neoplasms
C0205748 BXGD004117 Dysplastic Nevus Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms
C0220630 BXGD004302 Adult Liver Carcinoma Digestive System Diseases; Neoplasms
C0220641 BXGD004305 Lip and Oral Cavity Carcinoma Neoplasms; Stomatognathic Diseases
C0231341 BXGD004492 Premature aging syndrome Pathological Conditions, Signs and Symptoms
C0235782 BXGD004769 Gallbladder Carcinoma Digestive System Diseases; Neoplasms
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0236642 BXGD004815 Pick Disease of the Brain Nervous System Diseases; Mental Disorders
C0238463 BXGD004938 Papillary thyroid carcinoma Neoplasms; Endocrine System Diseases
C0239946 BXGD005010 Fibrosis, Liver Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0263630 BXGD005335 Hypertrophic disorder of skin, unspecified Skin and Connective Tissue Diseases
C0268398 BXGD005933 Familial lichen amyloidosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C0271650 BXGD006227 Impaired glucose tolerance Nutritional and Metabolic Diseases
C0278510 BXGD006526 Childhood Medulloblastoma Neoplasms
C0278595 BXGD006545 Adult Fibrosarcoma Neoplasms
C0278876 BXGD006607 Adult Medulloblastoma Neoplasms
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0278883 BXGD006614 Metastatic melanoma Neoplasms
C0279000 BXGD006622 Liver and Intrahepatic Biliary Tract Carcinoma Digestive System Diseases; Neoplasms
C0279626 BXGD006657 Squamous cell carcinoma of esophagus Digestive System Diseases; Neoplasms
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0280100 BXGD006713 Solid Neoplasm Neoplasms
C0280324 BXGD006740 Laryngeal Squamous Cell Carcinoma Neoplasms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0282612 BXGD006820 Prostatic Intraepithelial Neoplasias Neoplasms
C0302180 BXGD006833 Condyloma
C0302592 BXGD006851 Cervix carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0338451 BXGD007176 Frontotemporal dementia Nutritional and Metabolic Diseases; Nervous System Diseases; Mental Disorders
C0340076 BXGD007302 Asthmatic pulmonary eosinophilia Respiratory Tract Diseases; Hemic and Lymphatic Diseases
C0342384 BXGD007470 Idiopathic hypogonadotropic hypogonadism Endocrine System Diseases
C0345904 BXGD007745 Malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0346429 BXGD007828 Multiple malignancy Neoplasms
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0405580 BXGD008325 Adrenal cortical hypofunction Endocrine System Diseases
C0424574 BXGD008534 Duration of sleep
C0426799 BXGD008578 Congenital hypoplasia of clavicle Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0476089 BXGD008977 Endometrial Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0494463 BXGD009029 Alzheimer Disease, Late Onset Nervous System Diseases; Mental Disorders
C0497327 BXGD009061 Dementia Nervous System Diseases; Mental Disorders
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0524909 BXGD009247 Hepatitis B, Chronic Digestive System Diseases; Infections
C0546837 BXGD009343 Malignant neoplasm of esophagus Digestive System Diseases; Neoplasms
C0553723 BXGD009416 Squamous cell carcinoma of skin Neoplasms; Skin and Connective Tissue Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0598766 BXGD009669 Leukemogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0677886 BXGD009734 Epithelial ovarian cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0677932 BXGD009736 Progressive Neoplastic Disease
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0729531 BXGD009928 Viral respiratory infection Infections; Respiratory Tract Diseases
C0740457 BXGD010000 Malignant neoplasm of kidney Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0750974 BXGD010270 Brain Tumor, Primary Neoplasms; Nervous System Diseases
C0751072 BXGD010312 Frontotemporal Lobar Degeneration Nutritional and Metabolic Diseases; Nervous System Diseases; Mental Disorders
C0856169 BXGD011096 Endothelial dysfunction
C0887833 BXGD011398 Carcinoma, Pancreatic Ductal Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0947751 BXGD011494 Vascular inflammations Cardiovascular Diseases
C0948008 BXGD011499 Ischemic stroke Nervous System Diseases; Cardiovascular Diseases
C0949664 BXGD011583 Tauopathies Nervous System Diseases
C1096063 BXGD011600 Drug Resistant Epilepsy Nervous System Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1168401 BXGD011792 Squamous cell carcinoma of the head and neck Neoplasms
C1257931 BXGD011815 Mammary Neoplasms, Human Neoplasms; Skin and Connective Tissue Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1270972 BXGD012006 Mild cognitive disorder Mental Disorders
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C1335302 BXGD012775 Pancreatic Ductal Adenocarcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C1336076 BXGD012828 Sporadic Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C1378703 BXGD012933 Renal carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1397307 BXGD012996 Cardiac fibrosis
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1512409 BXGD013188 Hepatocarcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C1561643 BXGD013363 Chronic Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1608408 BXGD013434 Malignant transformation
C1611743 BXGD013456 Familial (FPAH)
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1832661 BXGD013866 ANOPHTHALMIA AND PULMONARY HYPOPLASIA Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Respiratory Tract Diseases
C1851841 BXGD015242 ECTRODACTYLY, ECTODERMAL DYSPLASIA, AND CLEFT LIP/PALATE SYNDROME 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Stomatognathic Diseases
C1960398 BXGD016658 HER2-positive carcinoma of breast Neoplasms; Skin and Connective Tissue Diseases
C1961099 BXGD016672 Precursor T-Cell Lymphoblastic Leukemia-Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2363741 BXGD017100 HIV-1 infection
C2699510 BXGD017460 Split-Hand/Foot Malformation Pathological Conditions, Signs and Symptoms
C2711227 BXGD017478 Steatohepatitis Digestive System Diseases
C2931822 BXGD018068 Nasopharyngeal carcinoma Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C2945759 BXGD018189 aggressive cancer
C3241937 BXGD018578 Nonalcoholic Steatohepatitis Digestive System Diseases
C3266262 BXGD018600 Multiple Chronic Conditions Pathological Conditions, Signs and Symptoms
C3469521 BXGD018910 FANCONI ANEMIA, COMPLEMENTATION GROUP A (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Hemic and Lymphatic Diseases
C3539781 BXGD019086 Progressive cGVHD
C3539878 BXGD019087 Triple Negative Breast Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C3811918 BXGD019664 GRN-related frontotemporal dementia Nutritional and Metabolic Diseases; Nervous System Diseases; Mental Disorders
C3854222 BXGD019826 Human immunodeficiency virus (HIV) II infection category B1
C3888088 BXGD019947 SMITH-MCCORT DYSPLASIA 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C4048328 BXGD021903 cervical cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4525297 BXGD023131 Stage 0 Gallbladder Cancer AJCC v8
C4525300 BXGD023132 Stage IIA Gallbladder Cancer AJCC v8
C4525301 BXGD023133 Stage IIB Gallbladder Cancer AJCC v8
C4525302 BXGD023134 Stage III Gallbladder Cancer AJCC v8
C4525305 BXGD023135 Stage IV Gallbladder Cancer AJCC v8
C4529962 BXGD023178 Fatty Liver Disease
C4703473 BXGD023650 Atherosclerotic lesion Cardiovascular Diseases
C4704874 BXGD023682 Mammary Carcinoma, Human Neoplasms; Skin and Connective Tissue Diseases
C4721579 BXGD023759 Secondary malignant neoplasm of colon and/or rectum Digestive System Diseases; Neoplasms
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
C4722518 BXGD023806 Triple-Negative Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C4733095 BXGD023910 HER2-negative breast cancer
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000205 Theobromine 180.16
BXGC0000279 L-Alanine 89.09
BXGC0000286 L-DOPA 197.19
BXGC0000288 L-Proline 115.13
BXGC0000324 Isovitexin 432.38
BXGC0000369 Methyl gallate 184.15
BXGC0000388 Nobiletin 402.39
BXGC0000397 Diosmetin 7-rutinoside 608.54
BXGC0000430 Gossypol 518.55
BXGC0000436 Glycerol 92.09
BXGC0000530 Hydroquinone 110.11
BXGC0000563 1H-Indole-3-methanol 147.17
BXGC0000647 L-Malic acid 134.09
BXGC0000651 Harmalan 184.24
BXGC0000679 Palmidrol 299.49
BXGC0000759 Arabinan 243.22
BXGC0000805 Bis(2-furanylmethyl) disulfide 226.32
BXGC0000988 3' 5'-cyclic AMP 329.21
BXGC0001002 1,2-Benzenediol 110.11
BXGC0001167 Isoorientin 7-O-(6'''-O-(E)-feruloyl)glucoside 448.38
BXGC0001199 3,3'-Dihydroxy-4,5-dimethoxybibenzyl 286.33
BXGC0001403 5-Hydroxy-3,3',4',6,7,8-hexamethoxyflavone 418.39
BXGC0001476 Girinimbine 263.33
BXGC0001495 (R)-Roemerine 279.33
BXGC0001498 Boldine 327.37
BXGC0001691 Questiomycin A 212.2
BXGC0001742 Eupafolin 316.26
BXGC0001782 Sennoside B 862.74
BXGC0001823 Morusinol 438.47
BXGC0001876 Chrysoeriol 300.26
BXGC0001940 Daphnetin 178.14
BXGC0001965 Hesperidin 610.56
BXGC0001991 Juglone 174.15
BXGC0002018 Morin 302.24
BXGC0002037 Pinocembrin 256.26
BXGC0002061 Aloeemodin 270.24
BXGC0002064 Amentoflavone 538.46
BXGC0002071 Apigenin 270.24
BXGC0002445 Nonanoic acid 158.24
BXGC0002906 Caffeic acid ester 284.31
BXGC0003452 Pectolinarigenin 314.29
BXGC0003705 Chloride 35.45
BXGC0003852 Nigrin B 506.47
BXGC0004276 Acetamide 59.07
BXGC0004322 xi-3-Hydroxy-5-phenylpentanoic acid O-beta-D-Glucopyranoside 356.37
BXGC0004965 Rhein 284.22
BXGC0005319 Garcinone E 464.55
BXGC0005502 Coumestrol 268.22
BXGC0005682 3,3',4,4'-Tetrahydroxylignan 302.36
BXGC0005683 Quercetin 302.24
BXGC0005721 Bisdemethoxycurcumin 308.33
BXGC0005793 Baicalein 270.24
BXGC0005981 (S)-4',5,7-Trihydroxy-8-prenylflavanone 340.38
BXGC0005982 Curcumin 368.38
BXGC0006062 Isoorientin 448.38
BXGC0006107 alpha-Linolenic acid 278.43
BXGC0006162 L-Glutamic acid 147.13
BXGC0006193 Ellagic acid 302.19
BXGC0006291 Scopoletin 192.17
BXGC0006306 Myricetin 318.24
BXGC0006308 Myricetin 3-rhamnoside 464.38
BXGC0006367 Mangiferin 422.34
BXGC0006635 Luteolin 286.24
BXGC0007029 Emodin 270.24
BXGC0007368 Luteolin 7-glucoside 448.38
BXGC0008181 Morusin 420.45
BXGC0008707 Isoliquiritigenin 256.25
BXGC0008912 Panasenoside 610.52
BXGC0008943 Kaempferol 3-robinobioside 594.52
BXGC0009194 Quercetin 3-glucuronide 478.36
BXGC0009332 Pelanin 356.5
BXGC0009649 Dihydrocapsaicin 307.43
BXGC0010010 3,8''-Biapigenin 538.46
BXGC0010427 Xanthotoxol geranyl ether 338.4
BXGC0010605 N-Malonylanthranilic acid 223.18
BXGC0011421 3-Hydroxy-1-(4-hydroxyphenyl)-1-propanone 166.17
BXGC0011627 Glycyrrhetic acid 470.69
BXGC0012874 Continentalic acid 302.22
BXGC0013582 Curcumin 368.13
BXGC0014019 (2S,3S)-2-Amino-3-Hydroxybutanedioic Acid 149.03
BXGC0014094 Norswertianolin 422.08
BXGC0014695 Loratadine 382.14
BXGC0014870 4,5-Dimethoxy-11-Methyl-[1,3]Dioxolo[4,5-C]Acridin-6-One 313.1
BXGC0014934 L-Norepinephrine 169.07
BXGC0015031 Diethyl Phthalate 222.09
BXGC0016681 Hispidin 246.05
BXGC0017158 thunberginol A 270.05
BXGC0017933 Sulfuretin 270.05
BXGC0018004 \N 186.08
BXGC0018071 Totarol 286.23
BXGC0018252 Embelin 294.18
BXGC0020012 [(1R,2R)-2,3-Dihydroxy-1-(7-Methoxy-2-Oxochromen-6-Yl)-3-Methylbutyl] (E)-2-Methylbut-2-Enoate 376.15
BXGC0020995 6-[(3E,5E,7S)-5,7-Dimethyl-2-Oxonona-3,5-Dienyl]-2,4-Dihydroxy-3-Methylbenzaldehyde 316.17
BXGC0021255 4-[(3S)-8,8-Dimethyl-3,4-Dihydro-2H-Pyrano[2,3-F]Chromen-3-Yl]Benzene-1,3-Diol 324.14
BXGC0021893 Norepinephrine 169.07
BXGC0022009 (9R)-9-[(9R)-2-Carboxy-4-Hydroxy-10-Oxo-5-[(3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Oxan-2-Yl]Oxy-9H-Anthracen-9-Yl]-4-Hydroxy-10-Oxo-5-[(2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Oxan-2-Yl]Oxy-9H-Anthracene-2-Carboxylic Acid 862.2
BXGC0022169 2-[(1S,6R)-6-(2,4-Dihydroxybenzoyl)-5-(2,4-Dihydroxyphenyl)-3-Methylcyclohex-2-En-1-Yl]-1,3,5A,8-Tetrahydroxy-10A-(3-Methylbut-2-Enyl)-[1]Benzofuro[3,2-B]Chromen-11-One 708.22
BXGC0022621 3-[(2S)-5,7-Dihydroxy-2-(4-Hydroxyphenyl)-3,4-Dihydro-2H-Chromen-8-Yl]-5,7-Dihydroxy-2-(4-Hydroxyphenyl)Chromen-4-One 526.13
BXGC0023321 Quercetin Dihydrate 302.04
BXGC0024428 3-(1H-Benzimidazol-2-Yl)-7-(Diethylamino)Chromen-2-One 333.15
BXGC0024813 Demethoxycurcumin 338.12
BXGC0025017 Bergamottin 338.15
BXGC0025862 Levothyroxine 776.69
BXGC0026125 Bellidifolin 274.05
BXGC0026480 Osajin 404.16
BXGC0026607 epiberberine 336.12
BXGC0026943 Toxyloxanthone C 328.09
BXGC0027421 Paclitaxel 853.33
BXGC0027536 Diosmin 608.17
BXGC0027644 2-(3,4-Dihydroxyphenyl)-5-Hydroxy-7-[(2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-Trihydroxy-6-Methyloxan-2-Yl]Oxymethyl]Oxan-2-Yl]Oxychromen-4-One 594.16
BXGC0028001 Beta-Lapachone 242.09
BXGC0028589 5,6,7,8-Tetrahydroxy-2-(4-Hydroxyphenyl)Chromen-4-One 302.04
BXGC0028823 (2R,3R,4S,5S,6R)-2-[[(1S,2R,3R)-7-Hydroxy-1-(4-Hydroxy-3,5-Dimethoxyphenyl)-3-(Hydroxymethyl)-6,8-Dimethoxy-1,2,3,4-Tetrahydronaphthalen-2-Yl]Methoxy]-6-(Hydroxymethyl)Oxane-3,4,5-Triol 582.23
BXGC0029379 Swertianolin 436.1
BXGC0029601 EUPAROTIN ACETATE 418.16
BXGC0029721 Sclerotiorin 390.12
BXGC0030248 2-(4-Hydroxyphenyl)Chromen-4-One 238.06
BXGC0030714 Daphnoretin 352.06
BXGC0030879 Mesodihydroguaiaretic Acid 330.18
BXGC0031002 Diffractaic Acid 374.14
BXGC0031090 Kazinol B 392.2
BXGC0031326 Paxilline 435.24
BXGC0031717 Purpurin 256.04
BXGC0032061 Methylmalonic Acid 118.03
BXGC0032635 [2-Methoxy-4-[(E)-Prop-1-Enyl]Phenyl] Acetate 206.09
BXGC0032911 1,3,4,5,6-Pentahydroxyhexan-2-One 180.06
BXGC0033310 Epigalocatechin Gallate 458.08
BXGC0033776 Cycloheximide 281.16
BXGC0034256 Rottlerin 516.18
BXGC0035197 Acetyl-11-Keto-Beta-Boswellic Acid 512.35
BXGC0035557 Pratol 268.07
BXGC0036458 4-(2-Methylbutan-2-Yl)Phenol 164.12
BXGC0036632 Austrobailignan 6 328.17
BXGC0036681 7,11B-Dihydro-6H-Indeno[2,1-C]Chromene-3,6A,9,10-Tetrol 286.08
BXGC0036864 Cyclovalone 366.15
BXGC0036918 5-Hydroxy-2-(4-Hydroxy-3,5-Dimethoxyphenyl)-6,7-Dimethoxychromen-4-One 374.1
BXGC0037718 Ethacrynic Acid 302.01
BXGC0037722 Pomiferin 420.16
BXGC0038066 Rescinnamine 634.29
BXGC0038083 Daphnorin 514.11
BXGC0038197 2-Methoxyphenazine 210.08
BXGC0038895 Emodic Acid 300.03
BXGC0039397 Athraquinones A 240.04
BXGC0039807 Nootkatin 232.15
BXGC0040358 Lobaric Acid 456.18
BXGC0040779 Gerontoxanthone I 396.16
BXGC0040936 Sid26657808 284.07
BXGC0041070 Taxol C 847.38
BXGC0041676 Pentamethylquercetin 372.12
BXGC0042035 raubasine 352.18
BXGC0042046 Actinodaphnine 311.12
BXGC0042107 Methyl 18-Hydroxy-1,3,11,12,14,15,16,17,18,19,20,21-Dodecahydroyohimban-19-Carboxylate 354.19
BXGC0042336 7-Amino-4-Hydroxynaphthalene-2-Sulfonic Acid 239.03
BXGC0042397 5,7-Dihydroxy-2-(4-Hydroxyphenyl)-6-Methyl-2,3-Dihydrochromen-4-One 286.08
BXGC0042546 5-Hydroxy-2-(4-Hydroxyphenyl)-7-Methoxy-2,3-Dihydrochromen-4-One 286.08
BXGC0043125 Taxifolin 304.06
BXGC0043126 Nicardipine 479.21
BXGC0043703 Domoic Acid 311.14
BXGC0043790 2-(2-Acetyl-3,5-Dihydroxyphenyl)Acetic Acid 210.05
BXGC0043875 Karanjin 292.07
BXGC0044857 Sp-600125 220.06
BXGC0046139 Aminoglutethimide 232.12
BXGC0046755 Yohimbine 354.19
BXGC0046862 Benzo[Def]Chrysene 252.09
BXGC0047186 (2S,3S)-2-(3,4-Dihydroxyphenyl)-5,7-Dihydroxy-3-[(2S,3R,4R,5R,6S)-3,4,5-Trihydroxy-6-Methyloxan-2-Yl]Oxy-2,3-Dihydrochromen-4-One 450.12
BXGC0047405 Gamolenic Acid 278.22
BXGC0048028 testosterone 288.21
BXGC0050184 Myricitrin 464.1
BXGC0050284 10-Hydroxycamptothecin 364.11
BXGC0050599 tetrandrine 622.3
BXGC0050726 5,7-Dihydroxy-2-(4-Hydroxyphenyl)-3-[(2R,3S,4R,5R,6S)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Oxan-2-Yl]Oxychromen-4-One 448.1
BXGC0051756 [8,8-Dimethyl-9-[(Z)-2-Methylbut-2-Enoyl]Oxy-2-Oxo-9,10-Dihydropyrano[2,3-F]Chromen-10-Yl] (Z)-2-Methylbut-2-Enoate 426.17
BXGC0051864 Aristolochic Acid 341.05
BXGC0052374 Reserpine 608.27
BXGC0052948 Tanshinone I 276.08
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein