Showing entry for Endothelin receptor type B


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT008975
Protein NameEndothelin receptor type B
Uniport IdP24530
GeneEDNRB
Gene Id1910
Domain7tm_1
Pfam PF00001  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04020 Calcium signaling pathway
3. Environmental Information Processing 3.2 Signal transduction hsa04022 cGMP-PKG signaling pathway
3. Environmental Information Processing 3.3 Signaling molecules and interaction hsa04080 Neuroactive ligand-receptor interaction
5. Organismal Systems 5.2 Endocrine system hsa04916 Melanogenesis
5. Organismal Systems 5.2 Endocrine system hsa04926 Relaxin signaling pathway
6. Human Diseases 6.1 Cancers: Overview hsa05200 Pathways in cancer
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007568 aging
Biological Process GO:0019722 calcium-mediated signaling
Biological Process GO:0007166 cell surface receptor signaling pathway
Biological Process GO:0071222 cellular response to lipopolysaccharide
Biological Process GO:0019934 cGMP-mediated signaling
Biological Process GO:0086100 endothelin receptor signaling pathway
Biological Process GO:0048484 enteric nervous system development
Biological Process GO:0035645 enteric smooth muscle cell differentiation
Biological Process GO:0042045 epithelial fluid transport
Biological Process GO:0007186 G protein-coupled receptor signaling pathway
Biological Process GO:0048246 macrophage chemotaxis
Biological Process GO:0030318 melanocyte differentiation
Biological Process GO:0007194 negative regulation of adenylate cyclase activity
Biological Process GO:0043066 negative regulation of apoptotic process
Biological Process GO:0032269 negative regulation of cellular protein metabolic process
Biological Process GO:0014043 negative regulation of neuron maturation
Biological Process GO:0000122 negative regulation of transcription by RNA polymerase II
Biological Process GO:0007399 nervous system development
Biological Process GO:0001755 neural crest cell migration
Biological Process GO:0007422 peripheral nervous system development
Biological Process GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway
Biological Process GO:0008284 positive regulation of cell population proliferation
Biological Process GO:0007204 positive regulation of cytosolic calcium ion concentration
Biological Process GO:0060406 positive regulation of penile erection
Biological Process GO:0001934 positive regulation of protein phosphorylation
Biological Process GO:0035815 positive regulation of renal sodium excretion
Biological Process GO:0035810 positive regulation of urine volume
Biological Process GO:0007497 posterior midgut development
Biological Process GO:0008217 regulation of blood pressure
Biological Process GO:0050678 regulation of epithelial cell proliferation
Biological Process GO:0031620 regulation of fever generation
Biological Process GO:0006885 regulation of pH
Biological Process GO:0051930 regulation of sensory perception of pain
Biological Process GO:1990839 response to endothelin
Biological Process GO:0014070 response to organic cyclic compound
Biological Process GO:0048265 response to pain
Biological Process GO:0019233 sensory perception of pain
Biological Process GO:0042310 vasoconstriction
Biological Process GO:0042311 vasodilation
Biological Process GO:0014826 vein smooth muscle contraction
molecular function GO:0004962 endothelin receptor activity
molecular function GO:0017046 peptide hormone binding
molecular function GO:0031702 type 1 angiotensin receptor binding
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0045121 membrane raft
cellular component GO:0031965 nuclear membrane
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-162582 Signal Transduction
R-HSA-372790 Signaling by GPCR
R-HSA-373076 Class A/1 (Rhodopsin-like receptors)
R-HSA-375276 Peptide ligand-binding receptors
R-HSA-388396 GPCR downstream signalling
R-HSA-416476 G alpha (q) signalling events
R-HSA-500792 GPCR ligand binding
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000737 BXGD000005 Abdominal Pain Pathological Conditions, Signs and Symptoms
C0001430 BXGD000054 Adenoma Neoplasms
C0001486 BXGD000056 Adenovirus Infections Infections
C0001883 BXGD000086 Airway Obstruction Respiratory Tract Diseases
C0001916 BXGD000089 Albinism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Eye Diseases; Skin and Connective Tissue Diseases
C0001973 BXGD000095 Alcoholic Intoxication, Chronic Chemically-Induced Disorders; Mental Disorders
C0003130 BXGD000183 Anoxia Pathological Conditions, Signs and Symptoms
C0003466 BXGD000193 Anus, Imperforate Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0004114 BXGD000255 Astrocytoma Neoplasms
C0004134 BXGD000256 Ataxia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0004238 BXGD000262 Atrial Fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0005684 BXGD000319 Malignant neoplasm of urinary bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005695 BXGD000323 Bladder Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005699 BXGD000325 Blast Phase Pathological Conditions, Signs and Symptoms; Neoplasms; Hemic and Lymphatic Diseases
C0005745 BXGD000331 Blepharoptosis Eye Diseases
C0005890 BXGD000345 Body Height
C0006111 BXGD000369 Brain Diseases Nervous System Diseases
C0006118 BXGD000372 Brain Neoplasms Neoplasms; Nervous System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007097 BXGD000424 Carcinoma Neoplasms
C0007103 BXGD000426 Malignant neoplasm of endometrium Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007134 BXGD000443 Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0007193 BXGD000451 Cardiomyopathy, Dilated Cardiovascular Diseases
C0007222 BXGD000454 Cardiovascular Diseases Cardiovascular Diseases
C0007682 BXGD000471 CNS disorder Nervous System Diseases
C0007785 BXGD000485 Cerebral Infarction Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0007820 BXGD000491 Cerebrovascular Disorders Nervous System Diseases; Cardiovascular Diseases
C0008497 BXGD000549 Choriocarcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0009681 BXGD000621 Anomalous pulmonary artery Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases
C0009806 BXGD000633 Constipation Pathological Conditions, Signs and Symptoms
C0010054 BXGD000647 Coronary Arteriosclerosis Cardiovascular Diseases
C0010674 BXGD000683 Cystic Fibrosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Respiratory Tract Diseases
C0011644 BXGD000744 Scleroderma Skin and Connective Tissue Diseases
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011991 BXGD000766 Diarrhea Pathological Conditions, Signs and Symptoms
C0013080 BXGD000797 Down Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0013146 BXGD000801 Drug abuse Chemically-Induced Disorders; Mental Disorders
C0013336 BXGD000815 Dwarfism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases
C0013502 BXGD000848 Echinococcosis Infections
C0014356 BXGD000910 Enterocolitis Digestive System Diseases
C0015652 BXGD001010 Fascioliasis Digestive System Diseases; Infections
C0015934 BXGD001026 Fetal Growth Retardation Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0017601 BXGD001125 Glaucoma Eye Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0017638 BXGD001132 Glioma Neoplasms
C0018776 BXGD001216 Hearing Loss, Central Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0018780 BXGD001218 Hearing Loss, High-Frequency Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0018784 BXGD001220 Sensorineural Hearing Loss (disorder) Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0018801 BXGD001226 Heart failure Cardiovascular Diseases
C0018802 BXGD001227 Congestive heart failure Cardiovascular Diseases
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0019284 BXGD001312 Diaphragmatic Hernia Pathological Conditions, Signs and Symptoms
C0019569 BXGD001337 Hirschsprung Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases
C0020429 BXGD001378 Hyperalgesia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0020541 BXGD001424 Portal Hypertension Digestive System Diseases
C0020542 BXGD001425 Pulmonary Hypertension Respiratory Tract Diseases
C0021099 BXGD001479 Impetigo Infections; Skin and Connective Tissue Diseases
C0021100 BXGD001480 Bullous impetigo Infections; Skin and Connective Tissue Diseases
C0021843 BXGD001520 Intestinal Obstruction Digestive System Diseases
C0022658 BXGD001570 Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0022679 BXGD001575 Cystic kidney Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023212 BXGD001616 Left-Sided Heart Failure Cardiovascular Diseases
C0023267 BXGD001626 Fibroid Tumor Neoplasms
C0023418 BXGD001642 leukemia Neoplasms
C0023449 BXGD001650 Acute lymphocytic leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023473 BXGD001661 Myeloid Leukemia, Chronic Neoplasms; Hemic and Lymphatic Diseases
C0023520 BXGD001678 Leukodystrophy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0023885 BXGD001711 Liver Abscess Digestive System Diseases; Infections
C0023890 BXGD001713 Liver Cirrhosis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0024115 BXGD001732 Lung diseases Respiratory Tract Diseases
C0024117 BXGD001734 Chronic Obstructive Airway Disease Respiratory Tract Diseases
C0024121 BXGD001735 Lung Neoplasms Neoplasms; Respiratory Tract Diseases
C0024312 BXGD001766 Lymphopenia Immune System Diseases; Hemic and Lymphatic Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0025160 BXGD001827 Megacolon Digestive System Diseases
C0025202 BXGD001832 melanoma Neoplasms
C0025286 BXGD001850 Meningioma Neoplasms; Nervous System Diseases
C0025958 BXGD001882 Microcephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0026764 BXGD001928 Multiple Myeloma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0026827 BXGD001936 Muscle hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027055 BXGD001964 Myocardial Reperfusion Injury Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027498 BXGD001994 Nausea and vomiting Pathological Conditions, Signs and Symptoms
C0027626 BXGD002005 Neoplasm Invasiveness Pathological Conditions, Signs and Symptoms; Neoplasms
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027720 BXGD002028 Nephrosis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0028738 BXGD002081 Nystagmus Eye Diseases; Nervous System Diseases
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0028840 BXGD002089 Ocular Hypertension Eye Diseases
C0028945 BXGD002099 oligodendroglioma Neoplasms
C0029132 BXGD002117 Disorder of the optic nerve Eye Diseases; Nervous System Diseases
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0030193 BXGD002191 Pain Pathological Conditions, Signs and Symptoms
C0031511 BXGD002304 Pheochromocytoma Neoplasms
C0032927 BXGD002381 Precancerous Conditions Neoplasms
C0033377 BXGD002406 Ptosis Pathological Conditions, Signs and Symptoms
C0033578 BXGD002408 Prostatic Neoplasms Neoplasms; Male Urogenital Diseases
C0035126 BXGD002509 Reperfusion Injury Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0036220 BXGD002587 Kaposi Sarcoma Neoplasms; Infections
C0036421 BXGD002613 Systemic Scleroderma Skin and Connective Tissue Diseases
C0036690 BXGD002632 Septicemia Pathological Conditions, Signs and Symptoms; Infections
C0037278 BXGD002678 Skin Diseases, Infectious Infections; Skin and Connective Tissue Diseases
C0037284 BXGD002679 Skin lesion Skin and Connective Tissue Diseases
C0037771 BXGD002702 Paraparesis, Spastic Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0038165 BXGD002735 Staphylococcal Scalded Skin Syndrome Infections; Skin and Connective Tissue Diseases
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0038525 BXGD002768 Subarachnoid Hemorrhage Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0039483 BXGD002813 Giant Cell Arteritis Skin and Connective Tissue Diseases; Immune System Diseases; Nervous System Diseases; Cardiovascular Diseases
C0040136 BXGD002845 Thyroid Neoplasm Neoplasms; Endocrine System Diseases
C0041296 BXGD002903 Tuberculosis Infections
C0041956 BXGD002942 Ureteral obstruction Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0042133 BXGD002960 Uterine Fibroids Neoplasms
C0085109 BXGD003125 Corneal Neovascularization Pathological Conditions, Signs and Symptoms; Eye Diseases
C0085413 BXGD003171 Polycystic Kidney, Autosomal Dominant Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0085580 BXGD003191 Essential Hypertension Cardiovascular Diseases
C0085758 BXGD003250 Aganglionosis, Colonic Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases
C0086692 BXGD003306 Benign Neoplasm Neoplasms
C0149931 BXGD003388 Migraine Disorders Nervous System Diseases
C0151546 BXGD003437 Oral Cavity Carcinoma Digestive System Diseases; Neoplasms; Stomatognathic Diseases
C0151650 BXGD003454 Renal fibrosis Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0151744 BXGD003469 Myocardial Ischemia Cardiovascular Diseases
C0151891 BXGD003499 Retinal depigmentation Pathological Conditions, Signs and Symptoms; Eye Diseases; Skin and Connective Tissue Diseases
C0152013 BXGD003516 Adenocarcinoma of lung (disorder) Neoplasms
C0152025 BXGD003521 Polyneuropathy Nervous System Diseases
C0152136 BXGD003548 Low Tension Glaucoma Eye Diseases
C0152171 BXGD003552 Idiopathic pulmonary hypertension Respiratory Tract Diseases; Cardiovascular Diseases
C0153349 BXGD003621 Malignant neoplasm of tongue Neoplasms; Stomatognathic Diseases
C0153381 BXGD003626 Malignant neoplasm of mouth Neoplasms; Stomatognathic Diseases
C0154723 BXGD003737 Migraine with Aura Nervous System Diseases
C0155877 BXGD003830 Allergic asthma Respiratory Tract Diseases; Immune System Diseases
C0162316 BXGD003936 Iron deficiency anemia Nutritional and Metabolic Diseases; Hemic and Lymphatic Diseases
C0162429 BXGD003942 Malnutrition Nutritional and Metabolic Diseases
C0162770 BXGD003980 Right Ventricular Hypertrophy Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0205748 BXGD004117 Dysplastic Nevus Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms
C0206698 BXGD004248 Cholangiocarcinoma Neoplasms
C0220630 BXGD004302 Adult Liver Carcinoma Digestive System Diseases; Neoplasms
C0220633 BXGD004303 Uveal melanoma Neoplasms; Eye Diseases
C0220641 BXGD004305 Lip and Oral Cavity Carcinoma Neoplasms; Stomatognathic Diseases
C0235480 BXGD004751 Paroxysmal atrial fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0235527 BXGD004753 Heart Failure, Right-Sided Cardiovascular Diseases
C0235833 BXGD004775 Congenital diaphragmatic hernia Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0238463 BXGD004938 Papillary thyroid carcinoma Neoplasms; Endocrine System Diseases
C0239946 BXGD005010 Fibrosis, Liver Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0242852 BXGD005197 Proliferative vitreoretinopathy Eye Diseases
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0262587 BXGD005259 Parathyroid Adenoma Neoplasms; Endocrine System Diseases
C0263498 BXGD005316 Premature canities
C0264716 BXGD005417 Chronic heart failure Cardiovascular Diseases
C0265252 BXGD005483 Coffin-Lowry syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0266292 BXGD005643 Congenital anomaly of the kidney Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0267373 BXGD005741 Intestinal hemorrhage NOS Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0268731 BXGD006029 Renal glomerular disease Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0270192 BXGD006066 Perinatal Subarachnoid Hemorrhage Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0278996 BXGD006621 Malignant Head and Neck Neoplasm Neoplasms
C0279000 BXGD006622 Liver and Intrahepatic Biliary Tract Carcinoma Digestive System Diseases; Neoplasms
C0279626 BXGD006657 Squamous cell carcinoma of esophagus Digestive System Diseases; Neoplasms
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0312414 BXGD006886 Menstrual spotting
C0339543 BXGD007267 Epiretinal Membrane Eye Diseases
C0339789 BXGD007282 Congenital deafness Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Nervous System Diseases; Otorhinolaryngologic Diseases
C0340543 BXGD007344 Familial primary pulmonary hypertension Respiratory Tract Diseases
C0342649 BXGD007522 Vascular calcification Nutritional and Metabolic Diseases
C0343401 BXGD007623 MRSA - Methicillin resistant Staphylococcus aureus infection Infections
C0344312 BXGD007665 White forelock Skin and Connective Tissue Diseases
C0345237 BXGD007720 Short segment Hirschsprung's disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases
C0345240 BXGD007721 Total intestinal aganglionosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases
C0345244 BXGD007722 Neuronal intestinal dysplasia Digestive System Diseases
C0345904 BXGD007745 Malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0349588 BXGD007933 Short stature
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0392514 BXGD008051 Hereditary hemochromatosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0423113 BXGD008473 Telecanthus Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0423318 BXGD008478 Heterochromia iridis Pathological Conditions, Signs and Symptoms; Eye Diseases; Skin and Connective Tissue Diseases
C0424678 BXGD008537 Lean body mass
C0431447 BXGD008690 Synophrys Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0454644 BXGD008850 Delayed speech and language development Behavior and Behavior Mechanisms
C0472383 BXGD008911 Subarachnoid Hemorrhage, Spontaneous Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0476089 BXGD008977 Endometrial Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0520679 BXGD009101 Sleep Apnea, Obstructive Respiratory Tract Diseases; Nervous System Diseases
C0521158 BXGD009130 Recurrent tumor
C0522216 BXGD009197 Abnormal auditory evoked potential
C0553580 BXGD009399 Ewings sarcoma Neoplasms
C0557874 BXGD009444 Global developmental delay
C0563625 BXGD009484 Agnosia for Pain Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0578626 BXGD009551 blue iris (physical finding)
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C0595921 BXGD009626 Intraocular pressure disorder Eye Diseases
C0596240 BXGD009638 Cancer Pain Pathological Conditions, Signs and Symptoms
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0600327 BXGD009704 Toxic Shock Syndrome Pathological Conditions, Signs and Symptoms; Infections
C0600452 BXGD009708 Hepatopulmonary Syndrome Digestive System Diseases; Respiratory Tract Diseases
C0678185 BXGD009744 Pemphigus neonatorum Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Immune System Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0699885 BXGD009869 Carcinoma of bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0751530 BXGD010493 Subarachnoid Hemorrhage, Aneurysmal Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0795688 BXGD010727 Subarachnoid Hemorrhage, Intracranial Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0852036 BXGD010934 Pregnancy associated hypertension Female Urogenital Diseases and Pregnancy Complications; Cardiovascular Diseases
C0856169 BXGD011096 Endothelial dysfunction
C0856554 BXGD011102 Hepatic cancer metastatic Digestive System Diseases; Neoplasms
C0859974 BXGD011205 Neonatal intestinal obstruction Digestive System Diseases
C0878544 BXGD011368 Cardiomyopathies Cardiovascular Diseases
C0948008 BXGD011499 Ischemic stroke Nervous System Diseases; Cardiovascular Diseases
C1168327 BXGD011787 High-Grade Prostatic Intraepithelial Neoplasia Neoplasms; Male Urogenital Diseases
C1168401 BXGD011792 Squamous cell carcinoma of the head and neck Neoplasms
C1257840 BXGD011809 Aganglionosis, Rectosigmoid Colon Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases
C1257915 BXGD011813 Intestinal Polyposis Digestive System Diseases
C1257931 BXGD011815 Mammary Neoplasms, Human Neoplasms; Skin and Connective Tissue Diseases
C1258666 BXGD011825 Myxoid cyst Neoplasms; Skin and Connective Tissue Diseases
C1262477 BXGD011882 Weight decreased Pathological Conditions, Signs and Symptoms
C1266042 BXGD011938 Chromophobe Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1275808 BXGD012094 Congenital central hypoventilation Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases; Nervous System Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C1332986 BXGD012574 Childhood Osteosarcoma Neoplasms
C1384666 BXGD012948 hearing impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C1449563 BXGD013086 Cardiomyopathy, Familial Idiopathic Cardiovascular Diseases
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1512419 BXGD013189 Hereditary Melanoma Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Skin and Connective Tissue Diseases
C1535510 BXGD013319 ADENOMAS AND ADENOCARCINOMAS Neoplasms
C1542647 BXGD013356 bullous staphylococcal impetigo Infections; Skin and Connective Tissue Diseases
C1568249 BXGD013420 Usher Syndrome, Type II Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Nervous System Diseases; Otorhinolaryngologic Diseases
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1623038 BXGD013475 Cirrhosis Pathological Conditions, Signs and Symptoms
C1658953 BXGD013486 tumor vasculature
C1704272 BXGD013537 Benign Prostatic Hyperplasia Male Urogenital Diseases
C1827849 BXGD013780 IgE-mediated allergic asthma Immune System Diseases
C1834055 BXGD013953 Underdeveloped nasal alae
C1836735 BXGD014155 hypopigmented skin patch Skin and Connective Tissue Diseases
C1836736 BXGD014156 White eyelashes
C1836737 BXGD014157 White eyebrow
C1838099 BXGD014294 ABCD syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C1838564 BXGD014319 HIRSCHSPRUNG DISEASE, SUSCEPTIBILITY TO, 2
C1847800 BXGD014889 Waardenburg Syndrome Type 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C1848395 BXGD014921 Large for gestational age Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications
C1848519 BXGD014932 WAARDENBURG SYNDROME, TYPE 4A Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases
C1849367 BXGD015046 Nasal bridge wide
C1853193 BXGD015312 Recurrent skin infections Infections; Skin and Connective Tissue Diseases
C1854113 BXGD015382 Prominent nasal bridge
C1855331 BXGD015488 Olfactory lobe agenesis
C1861537 BXGD016058 OROFACIAL CLEFT 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases
C1862475 BXGD016132 Abnormality of retinal pigmentation
C1867873 BXGD016473 Failure to thrive in infancy
C1959583 BXGD016637 Myocardial Failure Cardiovascular Diseases
C1961112 BXGD016674 Heart Decompensation Cardiovascular Diseases
C1963184 BXGD016688 Nystagmus, CTCAE 3.0
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2700265 BXGD017464 Waardenburg Syndrome Type 2 Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C2919142 BXGD017867 Short Stature, CTCAE
C2931822 BXGD018068 Nasopharyngeal carcinoma Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C2986682 BXGD018238 Locally Recurrent Malignant Neoplasm
C3203102 BXGD018555 Idiopathic pulmonary arterial hypertension Respiratory Tract Diseases
C3266898 BXGD018606 Waardenburg Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C3495676 BXGD019000 Anorectal Malformations Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases
C3554617 BXGD019228 Adducted thumb Musculoskeletal Diseases
C3661523 BXGD019265 Congenital Intestinal Aganglionosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases
C3714602 BXGD019416 Staphylococcal toxic shock syndrome Pathological Conditions, Signs and Symptoms; Infections
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C3714941 BXGD019439 OTOFACIOCERVICAL SYNDROME 1
C3887461 BXGD019876 Head and Neck Carcinoma Neoplasms
C3887514 BXGD019888 Chromophobe carcinoma
C4023346 BXGD021160 Aganglionosis of the small intestine
C4025846 BXGD021826 Abnormality of vision
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4509226 BXGD022972 Heart failure with preserved ejection fraction [HFpEF]
C4520679 BXGD023033 Abnormal macular morphology Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C4521042 BXGD023055 Complete Trisomy 21 Syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C4551649 BXGD023382 Congenital Dysplasia Of The Hip Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C4551683 BXGD023389 Adrenal Gland Pheochromocytoma Neoplasms; Endocrine System Diseases
C4553297 BXGD023538 Cystic Echinocccosis Infections
C4554036 BXGD023557 Nystagmus, CTCAE 5.0
C4704874 BXGD023682 Mammary Carcinoma, Human Neoplasms; Skin and Connective Tissue Diseases
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0006198 Citric acid 192.12
BXGC0028471 Monoolein 356.29
BXGC0051235 Phyllanthin 418.24
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein