Showing entry for Serine/threonine-protein kinase receptor R3


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT009953
Protein NameSerine/threonine-protein kinase receptor R3
Uniport IdP37023
GeneACVRL1
Gene Id94
DomainPkinase_Tyr; TGF_beta_GS
Pfam PF07714   PF08515  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.3 Signaling molecules and interaction hsa04060 Cytokine-cytokine receptor interaction
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0001525 angiogenesis
Biological Process GO:0060840 artery development
Biological Process GO:0008015 blood circulation
Biological Process GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis
Biological Process GO:0001955 blood vessel maturation
Biological Process GO:0001974 blood vessel remodeling
Biological Process GO:0030509 BMP signaling pathway
Biological Process GO:0071773 cellular response to BMP stimulus
Biological Process GO:0071363 cellular response to growth factor stimulus
Biological Process GO:0071560 cellular response to transforming growth factor beta stimulus
Biological Process GO:0009953 dorsal/ventral pattern formation
Biological Process GO:0035912 dorsal aorta morphogenesis
Biological Process GO:0003203 endocardial cushion morphogenesis
Biological Process GO:0061154 endothelial tube morphogenesis
Biological Process GO:0007507 heart development
Biological Process GO:0001701 in utero embryonic development
Biological Process GO:0001946 lymphangiogenesis
Biological Process GO:0060836 lymphatic endothelial cell differentiation
Biological Process GO:0043537 negative regulation of blood vessel endothelial cell migration
Biological Process GO:0007162 negative regulation of cell adhesion
Biological Process GO:0030308 negative regulation of cell growth
Biological Process GO:0030336 negative regulation of cell migration
Biological Process GO:0008285 negative regulation of cell population proliferation
Biological Process GO:2000279 negative regulation of DNA biosynthetic process
Biological Process GO:0045602 negative regulation of endothelial cell differentiation
Biological Process GO:0010596 negative regulation of endothelial cell migration
Biological Process GO:0001937 negative regulation of endothelial cell proliferation
Biological Process GO:0051895 negative regulation of focal adhesion assembly
Biological Process GO:0010629 negative regulation of gene expression
Biological Process GO:0045766 positive regulation of angiogenesis
Biological Process GO:0030513 positive regulation of BMP signaling pathway
Biological Process GO:0032332 positive regulation of chondrocyte differentiation
Biological Process GO:0045603 positive regulation of endothelial cell differentiation
Biological Process GO:0001938 positive regulation of endothelial cell proliferation
Biological Process GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation
Biological Process GO:0045893 positive regulation of transcription, DNA-templated
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:0006468 protein phosphorylation
Biological Process GO:0008217 regulation of blood pressure
Biological Process GO:0043535 regulation of blood vessel endothelial cell migration
Biological Process GO:0006275 regulation of DNA replication
Biological Process GO:0001936 regulation of endothelial cell proliferation
Biological Process GO:0006355 regulation of transcription, DNA-templated
Biological Process GO:0001666 response to hypoxia
Biological Process GO:0061298 retina vasculature development in camera-type eye
Biological Process GO:0007165 signal transduction
Biological Process GO:0007179 transforming growth factor beta receptor signaling pathway
Biological Process GO:0060841 venous blood vessel development
Biological Process GO:0035313 wound healing, spreading of epidermal cells
molecular function GO:0048185 activin binding
molecular function GO:0016361 activin receptor activity, type I
molecular function GO:0005524 ATP binding
molecular function GO:0098821 BMP receptor activity
molecular function GO:0046872 metal ion binding
molecular function GO:0019901 protein kinase binding
molecular function GO:0004674 protein serine/threonine kinase activity
molecular function GO:0046332 SMAD binding
molecular function GO:0005024 transforming growth factor beta-activated receptor activity
molecular function GO:0050431 transforming growth factor beta binding
molecular function GO:0005025 transforming growth factor beta receptor activity, type I
molecular function GO:0004675 transmembrane receptor protein serine/threonine kinase activity
cellular component GO:0070724 BMP receptor complex
cellular component GO:0009986 cell surface
cellular component GO:0030425 dendrite
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0043025 neuronal cell body
cellular component GO:0005886 plasma membrane
cellular component GO:0043235 receptor complex
Reactome
Pathway Id Pathway Name
R-HSA-162582 Signal Transduction
R-HSA-201451 Signaling by BMP
R-HSA-9006936 Signaling by TGFB family members
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000768 BXGD000007 Congenital Abnormality Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002418 BXGD000112 Amblyopia Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0002793 BXGD000130 Anaplasia Pathological Conditions, Signs and Symptoms; Neoplasms
C0002871 BXGD000132 Anemia Hemic and Lymphatic Diseases
C0002991 BXGD000167 Cutaneous Fibrous Histiocytoma Neoplasms
C0003486 BXGD000197 Aortic Aneurysm Cardiovascular Diseases
C0003857 BXGD000228 Congenital arteriovenous malformation Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0005779 BXGD000336 Blood Coagulation Disorders Hemic and Lymphatic Diseases
C0006105 BXGD000366 Brain Abscess Infections; Nervous System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006287 BXGD000390 Bronchopulmonary Dysplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007134 BXGD000443 Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0007222 BXGD000454 Cardiovascular Diseases Cardiovascular Diseases
C0007772 BXGD000480 Intracranial Arteriovenous Malformation Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Cardiovascular Diseases
C0007787 BXGD000487 Transient Ischemic Attack Nervous System Diseases; Cardiovascular Diseases
C0008325 BXGD000529 Cholecystitis Digestive System Diseases
C0008350 BXGD000531 Cholelithiasis Digestive System Diseases
C0008626 BXGD000559 Congenital chromosomal disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0009080 BXGD000580 Clubbed Fingers Musculoskeletal Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0009782 BXGD000631 Connective Tissue Diseases Skin and Connective Tissue Diseases
C0010520 BXGD000675 Cyanosis Pathological Conditions, Signs and Symptoms
C0011881 BXGD000760 Diabetic Nephropathy Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0013404 BXGD000833 Dyspnea Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases
C0013595 BXGD000858 Eczema Skin and Connective Tissue Diseases
C0014591 BXGD000938 Epistaxis Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0014867 BXGD000964 Esophageal Varices Digestive System Diseases
C0015934 BXGD001026 Fetal Growth Retardation Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0017181 BXGD001103 Gastrointestinal Hemorrhage Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0018801 BXGD001226 Heart failure Cardiovascular Diseases
C0018802 BXGD001227 Congestive heart failure Cardiovascular Diseases
C0018920 BXGD001246 Hemangioma, Cavernous Neoplasms; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0018926 BXGD001250 Hematemesis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0018932 BXGD001251 Hematochezia Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0018965 BXGD001258 Hematuria Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0019079 BXGD001278 Hemoptysis Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0019829 BXGD001350 Hodgkin Disease Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0020179 BXGD001363 Huntington Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders
C0020456 BXGD001392 Hyperglycemia Nutritional and Metabolic Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0020541 BXGD001424 Portal Hypertension Digestive System Diseases
C0020542 BXGD001425 Pulmonary Hypertension Respiratory Tract Diseases
C0020981 BXGD001474 Angioimmunoblastic Lymphadenopathy Immune System Diseases; Hemic and Lymphatic Diseases
C0023269 BXGD001627 leiomyosarcoma Neoplasms
C0023418 BXGD001642 leukemia Neoplasms
C0023508 BXGD001675 White Blood Cell Count procedure
C0023890 BXGD001713 Liver Cirrhosis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0023895 BXGD001717 Liver diseases Digestive System Diseases
C0024299 BXGD001758 Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024301 BXGD001759 Lymphoma, Follicular Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0025202 BXGD001832 melanoma Neoplasms
C0025222 BXGD001838 Melena Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0026764 BXGD001928 Multiple Myeloma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0026936 BXGD001950 Mycoplasma Infections Infections
C0026948 BXGD001952 Mycosis Fungoides Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0029182 BXGD002121 orbit (eye disorders) Eye Diseases
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0030297 BXGD002204 Pancreatic Neoplasm Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0032461 BXGD002356 Polycythemia Hemic and Lymphatic Diseases
C0032584 BXGD002363 polyps Pathological Conditions, Signs and Symptoms
C0034065 BXGD002454 Pulmonary Embolism Respiratory Tract Diseases; Cardiovascular Diseases
C0034091 BXGD002463 Pulmonary Veno-Occlusive Disease (disorder) Respiratory Tract Diseases; Cardiovascular Diseases
C0035309 BXGD002530 Retinal Diseases Eye Diseases
C0035412 BXGD002548 Rhabdomyosarcoma Neoplasms
C0036421 BXGD002613 Systemic Scleroderma Skin and Connective Tissue Diseases
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0037274 BXGD002676 Dermatologic disorders Skin and Connective Tissue Diseases
C0037579 BXGD002694 Soft Tissue Neoplasms Neoplasms
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0038525 BXGD002768 Subarachnoid Hemorrhage Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0039445 BXGD002810 Hereditary hemorrhagic telangiectasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0039446 BXGD002811 Telangiectasis Cardiovascular Diseases
C0042133 BXGD002960 Uterine Fibroids Neoplasms
C0042373 BXGD002978 Vascular Diseases Cardiovascular Diseases
C0042487 BXGD002986 Venous Thrombosis Cardiovascular Diseases
C0043208 BXGD003039 Wolman Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0079744 BXGD003090 Diffuse Large B-Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0079772 BXGD003099 T-Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0079774 BXGD003101 Peripheral T-Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0085411 BXGD003169 Angiodysplasia Cardiovascular Diseases
C0085576 BXGD003188 Iron-Refractory Iron Deficiency Anemia Nutritional and Metabolic Diseases; Hemic and Lymphatic Diseases
C0085580 BXGD003191 Essential Hypertension Cardiovascular Diseases
C0085605 BXGD003200 Liver Failure Digestive System Diseases
C0149651 BXGD003342 Clubbing
C0149931 BXGD003388 Migraine Disorders Nervous System Diseases
C0152171 BXGD003552 Idiopathic pulmonary hypertension Respiratory Tract Diseases; Cardiovascular Diseases
C0154835 BXGD003748 Retinal telangiectasia Cardiovascular Diseases
C0155675 BXGD003808 Pulmonary Arteriovenous Fistulas Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0158570 BXGD003892 Vascular anomaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0200637 BXGD004042 Monocyte count procedure
C0206138 BXGD004158 CREST Syndrome Digestive System Diseases; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases; Cardiovascular Diseases
C0206139 BXGD004159 Lichen Planus, Oral Skin and Connective Tissue Diseases; Stomatognathic Diseases
C0206180 BXGD004170 Ki-1+ Anaplastic Large Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0206644 BXGD004209 Histiocytoma, Benign Fibrous Neoplasms
C0206645 BXGD004210 Desmoplastic fibroma Neoplasms
C0206754 BXGD004289 Neuroendocrine Tumors Neoplasms
C0220611 BXGD004295 Childhood Rhabdomyosarcoma Neoplasms
C0220630 BXGD004302 Adult Liver Carcinoma Digestive System Diseases; Neoplasms
C0220650 BXGD004310 Metastatic malignant neoplasm to brain Pathological Conditions, Signs and Symptoms; Neoplasms; Nervous System Diseases
C0221045 BXGD004378 High output heart failure Cardiovascular Diseases
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0239105 BXGD004962 Conjunctival telangiectasis
C0241790 BXGD005114 Congenital pulmonary arteriovenous malformation Respiratory Tract Diseases
C0242383 BXGD005160 Age related macular degeneration Eye Diseases
C0265333 BXGD005519 Tricho-dento-osseous syndrome (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Stomatognathic Diseases
C0267370 BXGD005739 Angiodysplasia of colon Digestive System Diseases; Cardiovascular Diseases
C0268596 BXGD006000 Multiple Acyl Coenzyme A Dehydrogenase Deficiency Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0278607 BXGD006548 Adult Leiomyosarcoma Neoplasms
C0278622 BXGD006551 Adult Malignant Peripheral Nerve Sheath Tumor Neoplasms; Nervous System Diseases
C0278678 BXGD006556 Metastatic Renal Cell Cancer
C0278996 BXGD006621 Malignant Head and Neck Neoplasm Neoplasms
C0279000 BXGD006622 Liver and Intrahepatic Biliary Tract Carcinoma Digestive System Diseases; Neoplasms
C0279550 BXGD006635 Adult Rhabdomyosarcoma Neoplasms
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0279986 BXGD006705 Childhood Leiomyosarcoma Neoplasms
C0279987 BXGD006706 Childhood Malignant Peripheral Nerve Sheath Tumor Neoplasms; Nervous System Diseases
C0280100 BXGD006713 Solid Neoplasm Neoplasms
C0334121 BXGD006996 Inflammatory Myofibroblastic Tumor Pathological Conditions, Signs and Symptoms
C0334463 BXGD007076 Malignant Fibrous Histiocytoma Neoplasms
C0334533 BXGD007105 Arteriovenous hemangioma Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Cardiovascular Diseases
C0339510 BXGD007257 Vitelliform Macular Dystrophy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0340100 BXGD007304 High altitude pulmonary edema Respiratory Tract Diseases
C0340542 BXGD007343 Sporadic primary pulmonary hypertension Respiratory Tract Diseases
C0340543 BXGD007344 Familial primary pulmonary hypertension Respiratory Tract Diseases
C0345893 BXGD007743 Juvenile polyposis syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Neoplasms
C0345904 BXGD007745 Malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0346053 BXGD007770 Atypical fibroxanthoma of skin Neoplasms
C0348023 BXGD007866 Spinal arteriovenous malformation Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases; Cardiovascular Diseases
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0392525 BXGD008052 Nephrolithiasis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0398635 BXGD008206 Thromboxane synthetase deficiency Hemic and Lymphatic Diseases
C0428871 BXGD008638 Right to left cardiovascular shunt (finding)
C0520557 BXGD009090 Arteriovenous malformation of liver Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0744321 BXGD010092 Gastrointestinal arteriovenous malformation Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0750880 BXGD010239 Monocyte count result
C0751690 BXGD010553 Malignant Peripheral Nerve Sheath Tumor Neoplasms; Nervous System Diseases
C0752156 BXGD010680 Dural Arteriovenous Fistula Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Cardiovascular Diseases
C0854242 BXGD011009 Gastrointestinal angiodysplasia
C0856169 BXGD011096 Endothelial dysfunction
C0917804 BXGD011413 Arteriovenous Malformations, Cerebral Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Cardiovascular Diseases
C0948008 BXGD011499 Ischemic stroke Nervous System Diseases; Cardiovascular Diseases
C1150929 BXGD011768 2-oxo-hept-3-ene-1,7-dioate hydratase activity
C1168401 BXGD011792 Squamous cell carcinoma of the head and neck Neoplasms
C1257915 BXGD011813 Intestinal Polyposis Digestive System Diseases
C1266121 BXGD011965 Myofibroma (morphologic abnormality) Neoplasms; Skin and Connective Tissue Diseases
C1266127 BXGD011968 Histiocytoma, Angiomatoid Fibrous Neoplasms
C1269955 BXGD012005 Tumor Cell Invasion
C1270972 BXGD012006 Mild cognitive disorder Mental Disorders
C1276146 BXGD012107 Cutaneous lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1301362 BXGD012291 Primary Cutaneous Anaplastic Large Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1302772 BXGD012311 Primary cutaneous lymphoma Neoplasms; Skin and Connective Tissue Diseases; Immune System Diseases; Hemic and Lymphatic Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1332079 BXGD012486 Anaplastic Large Cell Lymphoma, ALK-Positive Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332182 BXGD012495 Adult Anaplastic Large Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332206 BXGD012504 Adult Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332214 BXGD012508 Adult Primary Cutaneous Anaplastic Large Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332942 BXGD012558 Childhood Anaplastic Large Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C1332979 BXGD012571 Childhood Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1335302 BXGD012775 Pancreatic Ductal Adenocarcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C1336548 BXGD012850 Systemic Anaplastic Large Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1368237 BXGD012896 Solitary Myofibromatosis Neoplasms
C1397307 BXGD012996 Cardiac fibrosis
C1458140 BXGD013134 Bleeding tendency Hemic and Lymphatic Diseases
C1519670 BXGD013241 Tumor Angiogenesis Pathological Conditions, Signs and Symptoms
C1562503 BXGD013374 Vein of Galen Malformations Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Cardiovascular Diseases
C1619711 BXGD013460 Gastrointestinal telangiectasia
C1623038 BXGD013475 Cirrhosis Pathological Conditions, Signs and Symptoms
C1658953 BXGD013486 tumor vasculature
C1697453 BXGD013507 Spontaneous hematomas
C1701938 BXGD013524 Associated Pulmonary Arterial Hypertension Respiratory Tract Diseases
C1701939 BXGD013525 Familial pulmonary arterial hypertension
C1832529 BXGD013852 HEREDITARY HEMORRHAGIC TELANGIECTASIA-RELATED PULMONARY ARTERIAL HYPERTENSION Respiratory Tract Diseases; Cardiovascular Diseases
C1838163 BXGD014298 OSLER-RENDU-WEBER SYNDROME 2 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C1838167 BXGD014299 Nail bed telangiectasia Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C1842180 BXGD014504 CAPILLARY MALFORMATION-ARTERIOVENOUS MALFORMATION (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Cardiovascular Diseases
C1855496 BXGD015502 Contiguous gene syndrome
C1857690 BXGD015737 Pulmonary arteriovenous malformation Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C1857697 BXGD015739 Lip telangiectasia
C1857699 BXGD015740 Palate telangiectasia
C1861248 BXGD016024 Fingerpad telangiectases
C1961121 BXGD016675 Congenital vascular anomaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2826323 BXGD017790 Refractory Cytopenia of Childhood
C2919945 BXGD017882 Cavernous Hemangioma of Brain Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C2931822 BXGD018068 Nasopharyngeal carcinoma Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C2937358 BXGD018159 Cerebral Hemorrhage Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C2973725 BXGD018205 Pulmonary arterial hypertension Respiratory Tract Diseases; Cardiovascular Diseases
C3203102 BXGD018555 Idiopathic pulmonary arterial hypertension Respiratory Tract Diseases
C3275758 BXGD018675 Choriocapillaris atrophy
C3809715 BXGD019607 Spontaneous, recurrent epistaxis Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C3850148 BXGD019811 Vascular Remodeling Pathological Conditions, Signs and Symptoms
C3852953 BXGD019814 Pulmonary Arterial Remodeling Pathological Conditions, Signs and Symptoms
C3887461 BXGD019876 Head and Neck Carcinoma Neoplasms
C3887658 BXGD019913 PULMONARY VENOOCCLUSIVE DISEASE 1, AUTOSOMAL DOMINANT Respiratory Tract Diseases; Cardiovascular Diseases
C4021971 BXGD020848 Peripheral arteriovenous fistula Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C4021977 BXGD020853 Visceral angiomatosis
C4022018 BXGD020872 Telangiectasia of the skin Cardiovascular Diseases
C4025853 BXGD021829 Nasal mucosa telangiectasia
C4025878 BXGD021841 Tongue telangiectasia
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4527152 BXGD023153 Tricuspid Valve Regurgitation Velocity
C4551861 BXGD023428 Telangiectasia, Hereditary Hemorrhagic, Type 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C4551903 BXGD023437 Total anomalous pulmonary venous return Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases; Cardiovascular Diseases
C4552070 BXGD023481 Pulmonary Hypertension, Primary, 1 Respiratory Tract Diseases
C4707243 BXGD023712 Familial thoracic aortic aneurysm and aortic dissection
C4721579 BXGD023759 Secondary malignant neoplasm of colon and/or rectum Digestive System Diseases; Neoplasms
C4721698 BXGD023763 Metastatic Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
C4727069 BXGD023850 Advanced Renal Cell Carcinoma
C4748670 BXGD024009 CAPILLARY MALFORMATION-ARTERIOVENOUS MALFORMATION 2
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0045254 Sb-202190 331.11
BXGC0047692 Gefitinib 446.15
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein