Showing entry for Tyrosine-protein kinase Fyn



                       
General Target Information
BXGT IdBXGT006429
Protein NameTyrosine-protein kinase Fyn
Uniport IdP06241
GeneFYN
Gene Id2534
DomainPkinase_Tyr; SH2; SH3_1
Pfam PF07714   PF00017   PF00018  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04071 Sphingolipid signaling pathway
3. Environmental Information Processing 3.2 Signal transduction hsa04072 Phospholipase D signaling pathway
5. Organismal Systems 5.8 Development hsa04360 Axon guidance
5. Organismal Systems 5.8 Development hsa04380 Osteoclast differentiation
4. Cellular Processes 4.3 Cellular community - eukaryotes hsa04510 Focal adhesion
4. Cellular Processes 4.3 Cellular community - eukaryotes hsa04520 Adherens junction
5. Organismal Systems 5.1 Immune system hsa04611 Platelet activation
5. Organismal Systems 5.1 Immune system hsa04650 Natural killer cell mediated cytotoxicity
5. Organismal Systems 5.1 Immune system hsa04660 T cell receptor signaling pathway
5. Organismal Systems 5.1 Immune system hsa04664 Fc epsilon RI signaling pathway
5. Organismal Systems 5.6 Nervous system hsa04725 Cholinergic synapse
6. Human Diseases 6.4 Neurodegenerative diseases hsa05020 Prion diseases
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05130 Pathogenic Escherichia coli infection
6. Human Diseases 6.6 Cardiovascular diseases hsa05416 Viral myocarditis
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0050798 activated T cell proliferation
Biological Process GO:0002250 adaptive immune response
Biological Process GO:0007411 axon guidance
Biological Process GO:0007596 blood coagulation
Biological Process GO:0006816 calcium ion transport
Biological Process GO:0030154 cell differentiation
Biological Process GO:1904646 cellular response to amyloid-beta
Biological Process GO:1905430 cellular response to glycine
Biological Process GO:1905232 cellular response to L-glutamate
Biological Process GO:0071375 cellular response to peptide hormone stimulus
Biological Process GO:0036120 cellular response to platelet-derived growth factor stimulus
Biological Process GO:0071560 cellular response to transforming growth factor beta stimulus
Biological Process GO:0019221 cytokine-mediated signaling pathway
Biological Process GO:0048813 dendrite morphogenesis
Biological Process GO:0097062 dendritic spine maintenance
Biological Process GO:0050966 detection of mechanical stimulus involved in sensory perception of pain
Biological Process GO:0048013 ephrin receptor signaling pathway
Biological Process GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis
Biological Process GO:0007631 feeding behavior
Biological Process GO:0030900 forebrain development
Biological Process GO:0003015 heart process
Biological Process GO:0045087 innate immune response
Biological Process GO:0035556 intracellular signal transduction
Biological Process GO:0007612 learning
Biological Process GO:0050900 leukocyte migration
Biological Process GO:0000165 MAPK cascade
Biological Process GO:0050804 modulation of chemical synaptic transmission
Biological Process GO:1902951 negative regulation of dendritic spine maintenance
Biological Process GO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
Biological Process GO:0010629 negative regulation of gene expression
Biological Process GO:0010730 negative regulation of hydrogen peroxide biosynthetic process
Biological Process GO:0043524 negative regulation of neuron apoptotic process
Biological Process GO:1903202 negative regulation of oxidative stress-induced cell death
Biological Process GO:0042177 negative regulation of protein catabolic process
Biological Process GO:0031397 negative regulation of protein ubiquitination
Biological Process GO:0001764 neuron migration
Biological Process GO:0038083 peptidyl-tyrosine autophosphorylation
Biological Process GO:0018108 peptidyl-tyrosine phosphorylation
Biological Process GO:0030168 platelet activation
Biological Process GO:2001056 positive regulation of cysteine-type endopeptidase activity
Biological Process GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
Biological Process GO:1901216 positive regulation of neuron death
Biological Process GO:0010976 positive regulation of neuron projection development
Biological Process GO:1903997 positive regulation of non-membrane spanning protein tyrosine kinase activity
Biological Process GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
Biological Process GO:0051897 positive regulation of protein kinase B signaling
Biological Process GO:1905477 positive regulation of protein localization to membrane
Biological Process GO:1900182 positive regulation of protein localization to nucleus
Biological Process GO:0090314 positive regulation of protein targeting to membrane
Biological Process GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein
Biological Process GO:0006468 protein phosphorylation
Biological Process GO:1905664 regulation of calcium ion import across plasma membrane
Biological Process GO:0042127 regulation of cell population proliferation
Biological Process GO:0008360 regulation of cell shape
Biological Process GO:0050690 regulation of defense response to virus by virus
Biological Process GO:1900449 regulation of glutamate receptor signaling pathway
Biological Process GO:0050730 regulation of peptidyl-tyrosine phosphorylation
Biological Process GO:1904645 response to amyloid-beta
Biological Process GO:0042493 response to drug
Biological Process GO:0045471 response to ethanol
Biological Process GO:0042542 response to hydrogen peroxide
Biological Process GO:0000304 response to singlet oxygen
Biological Process GO:0002223 stimulatory C-type lectin receptor signaling pathway
Biological Process GO:0031295 T cell costimulation
Biological Process GO:0050852 T cell receptor signaling pathway
Biological Process GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
Biological Process GO:0048010 vascular endothelial growth factor receptor signaling pathway
molecular function GO:0043014 alpha-tubulin binding
molecular function GO:0005524 ATP binding
molecular function GO:0042609 CD4 receptor binding
molecular function GO:0042610 CD8 receptor binding
molecular function GO:0097718 disordered domain specific binding
molecular function GO:0019899 enzyme binding
molecular function GO:0046875 ephrin receptor binding
molecular function GO:0070851 growth factor receptor binding
molecular function GO:0042802 identical protein binding
molecular function GO:0044325 ion channel binding
molecular function GO:0046872 metal ion binding
molecular function GO:0004715 non-membrane spanning protein tyrosine kinase activity
molecular function GO:0051428 peptide hormone receptor binding
molecular function GO:0043548 phosphatidylinositol 3-kinase binding
molecular function GO:0004713 protein tyrosine kinase activity
molecular function GO:0005102 signaling receptor binding
molecular function GO:0048156 tau protein binding
molecular function GO:0050321 tau-protein kinase activity
molecular function GO:0042608 T cell receptor binding
molecular function GO:0031802 type 5 metabotropic glutamate receptor binding
cellular component GO:0005884 actin filament
cellular component GO:0044297 cell body
cellular component GO:0005829 cytosol
cellular component GO:0030425 dendrite
cellular component GO:0005768 endosome
cellular component GO:0031234 extrinsic component of cytoplasmic side of plasma membrane
cellular component GO:0097386 glial cell projection
cellular component GO:0045121 membrane raft
cellular component GO:0005739 mitochondrion
cellular component GO:0005634 nucleus
cellular component GO:0097038 perinuclear endoplasmic reticulum
cellular component GO:0048471 perinuclear region of cytoplasm
cellular component GO:0005886 plasma membrane
cellular component GO:0014069 postsynaptic density
cellular component GO:0098685 Schaffer collateral - CA1 synapse
Reactome
Pathway Id Pathway Name
R-HSA-109582 Hemostasis
R-HSA-114604 GPVI-mediated activation cascade
R-HSA-1227986 Signaling by ERBB2
R-HSA-1257604 PIP3 activates AKT signaling
R-HSA-1266738 Developmental Biology
R-HSA-1266738 Developmental Biology
R-HSA-1280215 Cytokine Signaling in Immune system
R-HSA-1280215 Cytokine Signaling in Immune system
R-HSA-1280218 Adaptive Immune System
R-HSA-1280218 Adaptive Immune System
R-HSA-1433557 Signaling by SCF-KIT
R-HSA-1433557 Signaling by SCF-KIT
R-HSA-1433559 Regulation of KIT signaling
R-HSA-1500931 Cell-Cell communication
R-HSA-1500931 Cell-Cell communication
R-HSA-162582 Signal Transduction
R-HSA-162582 Signal Transduction
R-HSA-162906 HIV Infection
R-HSA-162909 Host Interactions of HIV factors
R-HSA-1643685 Disease
R-HSA-164944 Nef and signal transduction
R-HSA-164952 The role of Nef in HIV-1 replication and disease pathogenesis
R-HSA-168249 Innate Immune System
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-168256 Immune System
R-HSA-194138 Signaling by VEGF
R-HSA-199418 Negative regulation of the PI3K/AKT network
R-HSA-202733 Cell surface interactions at the vascular wall
R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis
R-HSA-2029481 FCGR activation
R-HSA-210990 PECAM1 interactions
R-HSA-2172127 DAP12 interactions
R-HSA-2172127 DAP12 interactions
R-HSA-2219528 PI3K/AKT Signaling in Cancer
R-HSA-2219530 Constitutive Signaling by Aberrant PI3K in Cancer
R-HSA-2424491 DAP12 signaling
R-HSA-2424491 DAP12 signaling
R-HSA-2454202 Fc epsilon receptor (FCERI) signaling
R-HSA-2682334 EPH-Ephrin signaling
R-HSA-2682334 EPH-Ephrin signaling
R-HSA-2730905 Role of LAT2/NTAL/LAB on calcium mobilization
R-HSA-373753 Nephrin family interactions
R-HSA-373753 Nephrin family interactions
R-HSA-373755 Semaphorin interactions
R-HSA-373755 Semaphorin interactions
R-HSA-375165 NCAM signaling for neurite out-growth
R-HSA-375165 NCAM signaling for neurite out-growth
R-HSA-388841 Costimulation by the CD28 family
R-HSA-389356 CD28 co-stimulation
R-HSA-389357 CD28 dependent PI3K/Akt signaling
R-HSA-389359 CD28 dependent Vav1 pathway
R-HSA-389513 CTLA4 inhibitory signaling
R-HSA-3928662 EPHB-mediated forward signaling
R-HSA-3928662 EPHB-mediated forward signaling
R-HSA-3928663 EPHA-mediated growth cone collapse
R-HSA-3928663 EPHA-mediated growth cone collapse
R-HSA-3928664 Ephrin signaling
R-HSA-3928664 Ephrin signaling
R-HSA-3928665 EPH-ephrin mediated repulsion of cells
R-HSA-399954 Sema3A PAK dependent Axon repulsion
R-HSA-399955 SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
R-HSA-399955 SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
R-HSA-399956 CRMPs in Sema3A signaling
R-HSA-399956 CRMPs in Sema3A signaling
R-HSA-422475 Axon guidance
R-HSA-422475 Axon guidance
R-HSA-4420097 VEGFA-VEGFR2 Pathway
R-HSA-449147 Signaling by Interleukins
R-HSA-449147 Signaling by Interleukins
R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling
R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling
R-HSA-5621480 Dectin-2 family
R-HSA-5621481 C-type lectin receptors (CLRs)
R-HSA-5621575 CD209 (DC-SIGN) signaling
R-HSA-5663202 Diseases of signal transduction by growth factor receptors and second messengers
R-HSA-5663205 Infectious disease
R-HSA-5673001 RAF/MAP kinase cascade
R-HSA-5683057 MAPK family signaling cascades
R-HSA-5684996 MAPK1/MAPK3 signaling
R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
R-HSA-75892 Platelet Adhesion to exposed collagen
R-HSA-76002 Platelet activation, signaling and aggregation
R-HSA-8866376 Reelin signalling pathway
R-HSA-9006925 Intracellular signaling by second messengers
R-HSA-9006934 Signaling by Receptor Tyrosine Kinases
R-HSA-9006934 Signaling by Receptor Tyrosine Kinases
R-HSA-912631 Regulation of signaling by CBL
R-HSA-912631 Regulation of signaling by CBL
R-HSA-9607240 FLT3 Signaling
R-HSA-9607240 FLT3 Signaling
R-HSA-9658195 Leishmania infection
R-HSA-9662851 Anti-inflammatory response favouring Leishmania parasite infection
R-HSA-9664323 FCGR3A-mediated IL10 synthesis
R-HSA-9664407 Parasite infection
R-HSA-9664417 Leishmania phagocytosis
R-HSA-9664422 FCGR3A-mediated phagocytosis
R-HSA-9664433 Leishmania parasite growth and survival
R-HSA-9669938 Signaling by KIT in disease
R-HSA-9670439 Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants
R-HSA-9675108 Nervous system development
R-HSA-9675108 Nervous system development
R-HSA-983695 Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
R-HSA-983705 Signaling by the B Cell Receptor (BCR)
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0001430 BXGD000054 Adenoma Neoplasms
C0001807 BXGD000077 Aggressive behavior Behavior and Behavior Mechanisms
C0001969 BXGD000094 Alcoholic Intoxication Chemically-Induced Disorders; Mental Disorders
C0001973 BXGD000095 Alcoholic Intoxication, Chronic Chemically-Induced Disorders; Mental Disorders
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002726 BXGD000125 Amyloidosis Nutritional and Metabolic Diseases
C0002957 BXGD000158 Anger Behavior and Behavior Mechanisms
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0005586 BXGD000315 Bipolar Disorder Mental Disorders
C0005684 BXGD000319 Malignant neoplasm of urinary bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005695 BXGD000323 Bladder Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005940 BXGD000352 Bone Diseases Musculoskeletal Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007112 BXGD000429 Adenocarcinoma of prostate Neoplasms; Male Urogenital Diseases
C0007115 BXGD000432 Malignant neoplasm of thyroid Neoplasms; Endocrine System Diseases
C0007370 BXGD000462 Catalepsy Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0007758 BXGD000475 Cerebellar Ataxia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0009241 BXGD000595 Cognition Disorders Mental Disorders
C0009806 BXGD000633 Constipation Pathological Conditions, Signs and Symptoms
C0011269 BXGD000710 Dementia, Vascular Nervous System Diseases; Mental Disorders; Cardiovascular Diseases
C0011854 BXGD000753 Diabetes Mellitus, Insulin-Dependent Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0013080 BXGD000797 Down Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0014544 BXGD000926 Epilepsy Nervous System Diseases
C0014556 BXGD000932 Epilepsy, Temporal Lobe Nervous System Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0020676 BXGD001462 Hypothyroidism Endocrine System Diseases
C0020981 BXGD001474 Angioimmunoblastic Lymphadenopathy Immune System Diseases; Hemic and Lymphatic Diseases
C0022104 BXGD001529 Irritable Bowel Syndrome Digestive System Diseases
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0023493 BXGD001672 Adult T-Cell Lymphoma/Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023893 BXGD001716 Liver Cirrhosis, Experimental Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0024121 BXGD001735 Lung Neoplasms Neoplasms; Respiratory Tract Diseases
C0024141 BXGD001740 Lupus Erythematosus, Systemic Skin and Connective Tissue Diseases; Immune System Diseases
C0024299 BXGD001758 Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0025500 BXGD001874 Mesothelioma Neoplasms
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0029417 BXGD002140 Osteoblastoma Neoplasms
C0029456 BXGD002157 Osteoporosis Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0029574 BXGD002165 Other dermatoses Skin and Connective Tissue Diseases
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0030569 BXGD002242 Secondary Parkinson Disease Nervous System Diseases
C0033578 BXGD002408 Prostatic Neoplasms Neoplasms; Male Urogenital Diseases
C0034069 BXGD002458 Pulmonary Fibrosis Respiratory Tract Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0037019 BXGD002658 Shy-Drager Syndrome Nervous System Diseases; Cardiovascular Diseases
C0037274 BXGD002676 Dermatologic disorders Skin and Connective Tissue Diseases
C0037277 BXGD002677 Skin Diseases, Genetic Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0038356 BXGD002747 Stomach Neoplasms Digestive System Diseases; Neoplasms
C0040136 BXGD002845 Thyroid Neoplasm Neoplasms; Endocrine System Diseases
C0079774 BXGD003101 Peripheral T-Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0085762 BXGD003251 Alcohol abuse Chemically-Induced Disorders; Mental Disorders
C0149782 BXGD003365 Squamous cell carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0149925 BXGD003387 Small cell carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0155877 BXGD003830 Allergic asthma Respiratory Tract Diseases; Immune System Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0206138 BXGD004158 CREST Syndrome Digestive System Diseases; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases; Cardiovascular Diseases
C0233612 BXGD004597 Waxy flexibility Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0233794 BXGD004618 Memory impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0235946 BXGD004789 Cerebral atrophy Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0238198 BXGD004893 Gastrointestinal Stromal Tumors Digestive System Diseases; Neoplasms
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0242422 BXGD005163 Parkinsonian Disorders Nervous System Diseases
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0278015 BXGD006491 Change in stool consistency
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0278883 BXGD006614 Metastatic melanoma Neoplasms
C0279626 BXGD006657 Squamous cell carcinoma of esophagus Digestive System Diseases; Neoplasms
C0280216 BXGD006719 stage, neuroblastoma Neoplasms
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0282612 BXGD006820 Prostatic Intraepithelial Neoplasias Neoplasms
C0338656 BXGD007211 Impaired cognition Mental Disorders
C0343386 BXGD007620 Clostridium difficile infection Infections
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0542476 BXGD009276 Forgetful Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0549473 BXGD009384 Thyroid carcinoma Neoplasms; Endocrine System Diseases
C0553723 BXGD009416 Squamous cell carcinoma of skin Neoplasms; Skin and Connective Tissue Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0687720 BXGD009844 Central Diabetes Insipidus Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0699885 BXGD009869 Carcinoma of bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0752347 BXGD010721 Lewy Body Disease Nervous System Diseases; Mental Disorders
C0871470 BXGD011316 Systolic Pressure
C0949664 BXGD011583 Tauopathies Nervous System Diseases
C1265996 BXGD011927 Large cell neuroendocrine carcinoma Neoplasms
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1334274 BXGD012695 Invasive Carcinoma Neoplasms
C1411966 BXGD013047 Clostridium; difficile (disorder)
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1510586 BXGD013176 Autism Spectrum Disorders Mental Disorders
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1704272 BXGD013537 Benign Prostatic Hyperplasia Male Urogenital Diseases
C1708349 BXGD013597 Hereditary Diffuse Gastric Cancer Digestive System Diseases; Neoplasms
C1832661 BXGD013866 ANOPHTHALMIA AND PULMONARY HYPOPLASIA Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Respiratory Tract Diseases
C2938924 BXGD018167 Oestrogen receptor positive breast cancer
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C3266262 BXGD018600 Multiple Chronic Conditions Pathological Conditions, Signs and Symptoms
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4521042 BXGD023055 Complete Trisomy 21 Syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C4551583 BXGD023361 Cerebral cortical atrophy
C4721507 BXGD023747 Alveolitis, Fibrosing Respiratory Tract Diseases
C4733092 BXGD023907 estrogen receptor-negative breast cancer
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000130 Estradiol 272.38
BXGC0000202 Papaverine 339.39
BXGC0000204 Theophylline 180.16
BXGC0000226 Glycine 75.07
BXGC0000284 alpha-Tocopherol 430.71
BXGC0000286 L-DOPA 197.19
BXGC0000433 Triacetin 218.2
BXGC0000434 Ethanol 46.07
BXGC0000436 Glycerol 92.09
BXGC0000439 Chloroform 119.38
BXGC0000441 Dimethyl sulfoxide 78.13
BXGC0000528 Salicylic acid 138.12
BXGC0000536 Phenol 94.11
BXGC0000537 Acetylsalicylic acid 180.16
BXGC0000622 Nicotinic acid 123.11
BXGC0000663 Papain 206.28
BXGC0000759 Arabinan 243.22
BXGC0000764 L-Ascorbic acid 176.12
BXGC0000894 2-Methylthioribosyl-trans-zeatin 323.8
BXGC0001000 4,8,5'-Trimethylpsoralen 228.24
BXGC0001002 1,2-Benzenediol 110.11
BXGC0001325 Progesterone 314.46
BXGC0001502 Caffeine 194.19
BXGC0001545 Harmine 212.25
BXGC0001550 Ficus Latex peptide 2 244.26
BXGC0001767 (E)-Resveratrol 228.25
BXGC0002012 (Z)-Isoeugenol 164.2
BXGC0002402 Ethyl carbamate 89.09
BXGC0002437 Lactic acid 90.08
BXGC0002441 Hydroxyacetic acid 76.05
BXGC0002627 17alpha-ethynylestradiol 296.4
BXGC0002796 Nicotine 162.23
BXGC0002867 Lappaurin 284.74
BXGC0002906 Caffeic acid ester 284.31
BXGC0002916 Melatonin 232.28
BXGC0003066 Phenols 199.27
BXGC0003131 N,N-Dimethylformamide 73.09
BXGC0003501 Parthenolide 248.32
BXGC0003502 Phenylhydrazine 108.14
BXGC0003611 Latex 416.57
BXGC0003690 Glucokinin 764.94
BXGC0003705 Chloride 35.45
BXGC0003707 Estrogen 268.36
BXGC0003773 Estriol 288.38
BXGC0003956 Fenugrin E 178.19
BXGC0004261 Propylene glycol 76.09
BXGC0004277 Acetic acid 60.05
BXGC0004287 Allyl alcohol 58.08
BXGC0004556 1,2,3-Benzenetriol 126.11
BXGC0004560 Benzoic acid 122.12
BXGC0004565 Benzyl alcohol 108.14
BXGC0004587 (E)-3-Phenyl-2-propenal 132.16
BXGC0004712 Methylparaben 152.15
BXGC0005398 (-)-alpha-Narcotine 413.42
BXGC0005508 Safrole 162.19
BXGC0005624 Genistein 270.24
BXGC0005702 2H-1-Benzopyran-2-one 146.15
BXGC0005871 Dopamine 153.18
BXGC0005879 Eugenol 164.2
BXGC0006105 Methyl salicylate 152.15
BXGC0006109 2-Aminoquinoline 144.17
BXGC0006115 Xanthotoxin 216.19
BXGC0006125 Nicotinamide 122.12
BXGC0006156 Dicoumarol 336.3
BXGC0006174 4-Hydroxybenzyl alcohol 124.14
BXGC0006198 Citric acid 192.12
BXGC0006362 Estrone 270.37
BXGC0006366 trans-Ferulic acid 194.18
BXGC0006368 Formic acid 46.03
BXGC0006372 Ergocalciferol 396.65
BXGC0006389 Rotenone 394.42
BXGC0006422 Mercenene 214.05
BXGC0006982 Geraniol 154.25
BXGC0007601 1,8-Cineole 154.25
BXGC0012228 Vitamin D 384.64
BXGC0012243 Ukonan D 151.16
BXGC0012352 Chelerythrine 348.12
BXGC0013452 Dioctyl phthalate 390.28
BXGC0014695 Loratadine 382.14
BXGC0015594 4-Nonylphenol 220.18
BXGC0015987 L-Mimosine 198.06
BXGC0016470 Camptothecin 348.11
BXGC0016671 Leucovorin 473.17
BXGC0016747 Camphor 152.12
BXGC0016891 Nortriptyline 263.17
BXGC0017115 Cephalexin 347.09
BXGC0017719 Strychnine 334.17
BXGC0018403 Hydroxyprogesterone 330.22
BXGC0018491 Methylprednisolone 374.21
BXGC0019117 Tannic Acid 1700.17
BXGC0019164 Raloxifene 473.17
BXGC0020355 Fomepizole 82.05
BXGC0020800 Testosterone 288.21
BXGC0021077 Aconitine 645.31
BXGC0021478 Lipoic Acid 206.04
BXGC0022544 Digoxin 780.43
BXGC0024141 Hydrocortisone 362.21
BXGC0024386 Atractyloside 724.21
BXGC0024413 Emetine 480.3
BXGC0024729 Mercaptopurine 152.02
BXGC0024988 Nifedipine 346.12
BXGC0025658 Vinblastine 810.42
BXGC0026391 Naloxone 327.15
BXGC0026595 Glycyrrhizin 822.4
BXGC0027374 Glyburide 493.14
BXGC0027421 Paclitaxel 853.33
BXGC0027854 Ethosuximide 141.08
BXGC0028885 Secobarbital 238.13
BXGC0030138 Colchicine 399.17
BXGC0030612 tetraethylene glycol 194.12
BXGC0030663 Metformin 129.1
BXGC0030685 Physostigmine 275.16
BXGC0031384 Epinephrine 183.09
BXGC0031622 Podofilox 414.13
BXGC0032368 Sparteine 234.21
BXGC0033776 Cycloheximide 281.16
BXGC0034035 Capsaicin 305.2
BXGC0034768 Vincristine 824.4
BXGC0034778 Artemisinin 282.15
BXGC0034783 Doxorubicin 543.17
BXGC0035519 Amygdalin 457.16
BXGC0037718 Ethacrynic Acid 302.01
BXGC0038963 Dichlorvos 219.95
BXGC0039601 Levocarnitine 161.11
BXGC0039684 Berberine Chloride 336.12
BXGC0040042 Warfarin 308.1
BXGC0040462 Aminosalicylic Acid 153.04
BXGC0041240 Atenolol 266.16
BXGC0042127 Oxyquinoline 145.05
BXGC0042179 Atropine 289.17
BXGC0042211 4-Octylphenol 206.17
BXGC0042222 Propranolol 259.16
BXGC0042339 Terbutaline 225.14
BXGC0042376 Picropodophyllotoxin 414.13
BXGC0042452 Panthenol 205.13
BXGC0042510 Fluoxetine 309.13
BXGC0042519 Glimepiride 490.22
BXGC0042596 Isoniazid 137.06
BXGC0043648 (-)-Camphor 152.12
BXGC0044017 Verapamil 454.28
BXGC0044810 Lamivudine 229.05
BXGC0044857 Sp-600125 220.06
BXGC0045254 Sb-202190 331.11
BXGC0045812 Trifluoperazine 407.16
BXGC0046139 Aminoglutethimide 232.12
BXGC0046755 Yohimbine 354.19
BXGC0046862 Benzo[Def]Chrysene 252.09
BXGC0046996 Thioguanine 167.03
BXGC0047126 Artemether 298.18
BXGC0047692 Gefitinib 446.15
BXGC0048313 Rosmarinic Acid 360.08
BXGC0049391 Betadex 1134.37
BXGC0049738 Dexibuprofen 206.13
BXGC0050099 (2E,5S,6S,8Z,11S)-5,6,15-Trihydroxy-17-Methoxy-11-Methyl-12-Oxabicyclo[12.4.0]Octadeca-1(14),2,8,15,17-Pentaene-7,13-Dione 362.14
BXGC0050471 Fluorouracil 130.02
BXGC0050816 Galantamine 287.15
BXGC0051524 Ouabain 584.28
BXGC0051982 Mannitol 182.08
BXGC0052021 (R)-Ibuprophen 206.13
BXGC0052374 Reserpine 608.27
BXGC0052878 Bisphenol A 228.12
BXGC0053118 Streptomycin 581.27
BXGC0053261 Antimycin A 548.27
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein