adisease

General Disease Information
BXGD Id	BXGD009991
Disease Name	Limb defects
Disease CUI Id	C0740404
MeSH Codes
Disease Class Name
Semantic Type	Congenital Abnormality
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00755	BXGT003945	Protein Wnt-7a	7476	reviewed	Signaling
O15119	BXGT004128	T-box transcription factor TBX3	6926	reviewed	Transcription factor
O75581	BXGT005136	Low-density lipoprotein receptor-related protein 6	4040	reviewed
O94907	BXGT005340	Dickkopf-related protein 1	22943	reviewed
P02452	BXGT005878	Collagen alpha-1(I) chain	1277	reviewed
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P04792	BXGT006264	Heat shock protein beta-1	3315	reviewed
P06702	BXGT006476	Protein S100-A9	6280	reviewed	Calcium-binding protein
P10070	BXGT007534	Zinc finger protein GLI2	2736	reviewed
P11362	BXGT007693	Fibroblast growth factor receptor 1	2260	reviewed	Kinase
P38919	BXGT010072	Eukaryotic initiation factor 4A-III	9775	reviewed
P40225	BXGT010168	Thrombopoietin	7066	reviewed
P46531	BXGT010526	Neurogenic locus notch homolog protein 1	4851	reviewed
P63000	BXGT011481	Ras-related C3 botulinum toxin substrate 1	5879	reviewed	Enzyme modulator
Q02127	BXGT012635	Dihydroorotate dehydrogenase (quinone), mitochondrial	1723	reviewed	Enzyme
Q15223	BXGT013551	Nectin-1	5818	reviewed
Q16719	BXGT013662	Kynureninase	8942	reviewed	Enzyme
Q96SW2	BXGT019743	Protein cereblon	51185	reviewed	Enzyme
Q99593	BXGT019939	T-box transcription factor TBX5	6910	reviewed	Transcription factor
Q9NYL2	BXGT021259	Mitogen-activated protein kinase kinase kinase 20	51776	reviewed	Kinase
Q9Y3B4	BXGT022255	Splicing factor 3B subunit 6	51639	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}