adisease

Showing entry for Juvenile Neuronal Ceroid Lipofuscinosis

General Disease Information
BXGD Id	BXGD010422
Disease Name	Juvenile Neuronal Ceroid Lipofuscinosis
Disease CUI Id	C0751383
MeSH Codes	C16 C18 C10
Disease Class Name	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id	DOID:0014667 DOID:630
Disease Ontology Class Name	disease of metabolism; genetic disease
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O14773	BXGT004096	Tripeptidyl-peptidase 1	1200	reviewed	Enzyme
O95278	BXGT005370	Laforin	7957	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P05067	BXGT006306	Amyloid-beta precursor protein	351	reviewed	Enzyme modulator
P07339	BXGT006604	Cathepsin D	1509	reviewed	Enzyme
P0DMM9	BXGT007504	Sulfotransferase 1A3	6818	reviewed
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P11308	BXGT007684	Transcriptional regulator ERG	2078	reviewed	Transcription factor
P20807	BXGT008601	Calpain-3	825	reviewed	Enzyme
P27361	BXGT009176	Mitogen-activated protein kinase 3	5595	reviewed	Kinase
P29466	BXGT009349	Caspase-1	834	reviewed	Enzyme
P41180	BXGT010230	Extracellular calcium-sensing receptor	846	reviewed	G-protein coupled receptor
P50225	BXGT010781	Sulfotransferase 1A1	6817	reviewed
P50897	BXGT010823	Palmitoyl-protein thioesterase 1	5538	reviewed	Enzyme
P51790	BXGT010890	H(+)/Cl(-) exchange transporter 3	1182	reviewed	Ion channel
P52594	BXGT010936	Arf-GAP domain and FG repeat-containing protein 1	3267	reviewed
P53396	BXGT010988	ATP-citrate synthase	47	reviewed	Enzyme
P60709	BXGT011322	Actin, cytoplasmic 1	60	reviewed	Cellular structure
Q05329	BXGT012814	Glutamate decarboxylase 2	2572	reviewed	Enzyme
Q16595	BXGT013643	Frataxin, mitochondrial	2395	reviewed	Enzyme
Q16637	BXGT013646	Survival motor neuron protein	6607	reviewed	Epigenetic regulator
Q5VZ30	BXGT015894	Glutamate decarboxylase 2 (Pancreatic islets and brain, 65kDa)	2572	unreviewed
Q8IVA8	BXGT018342	Glutamate decarboxylase 1 (Brain, 67kDa)	2571	unreviewed
Q99259	BXGT019915	Glutamate decarboxylase 1	2571	reviewed	Enzyme
Q9Y2W7	BXGT022250	Calsenilin	30818	reviewed	Ion channel
A6NHC0	BXGT022690	Calpain-8	388743	reviewed
P00738	BXGT022874	Haptoglobin	3240	reviewed	Enzyme

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}