adisease

Showing entry for ATRIOVENTRICULAR CANAL DEFECT

General Disease Information
BXGD Id	BXGD012962
Disease Name	ATRIOVENTRICULAR CANAL DEFECT
Disease CUI Id	C1389016
MeSH Codes	C16 C14
Disease Class Name	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
Semantic Type	Anatomical Abnormality
Human Phenotype Ontology Id	HP:0001626
Human Phenotype Ontology Term	Abnormality of the cardiovascular system
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O15151	BXGT004132	Protein Mdm4	4194	reviewed	Nucleic acid binding
O43318	BXGT004586	Mitogen-activated protein kinase kinase kinase 7	6885	reviewed	Kinase
O95644	BXGT005389	Nuclear factor of activated T-cells, cytoplasmic 1	4772	reviewed	Transcription factor
P01133	BXGT005736	Pro-epidermal growth factor	1950	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P04049	BXGT006133	RAF proto-oncogene serine/threonine-protein kinase	5894	reviewed	Kinase
P08151	BXGT006731	Zinc finger protein GLI1	2735	reviewed
P12821	BXGT007849	Angiotensin-converting enzyme	1636	reviewed	Enzyme
P15056	BXGT008075	Serine/threonine-protein kinase B-raf	673	reviewed	Kinase
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P21333	BXGT008638	Filamin-A	2316	reviewed
P24468	BXGT008969	COUP transcription factor 2	7026	reviewed	Nuclear receptor
P36894	BXGT009939	Bone morphogenetic protein receptor type-1A	657	reviewed	Kinase
P41440	BXGT010261	Folate transporter 1	6573	reviewed	Transporter
P52952	BXGT010966	Homeobox protein Nkx-2.5	1482	reviewed	Transcription factor
Q04771	BXGT012783	Activin receptor type-1	90	reviewed	Kinase
Q06124	BXGT012856	Tyrosine-protein phosphatase non-receptor type 11	5781	reviewed
Q13705	BXGT013393	Activin receptor type-2B	93	reviewed	Kinase
Q96PY6	BXGT019712	Serine/threonine-protein kinase Nek1	4750	reviewed	Kinase
Q99593	BXGT019939	T-box transcription factor TBX5	6910	reviewed	Transcription factor
Q99707	BXGT019952	Methionine synthase	4548	reviewed
Q9UBM7	BXGT021657	7-dehydrocholesterol reductase	1717	reviewed	Enzyme

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}