Showing entry for 7-dehydrocholesterol reductase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT021657
Protein Name7-dehydrocholesterol reductase
Uniport IdQ9UBM7
GeneDHCR7
Gene Id1717
DomainERG4_ERG24
Pfam PF01222  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.3 Lipid metabolism hsa00100 Steroid biosynthesis
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0001568 blood vessel development
Biological Process GO:0016132 brassinosteroid biosynthetic process
Biological Process GO:0030154 cell differentiation
Biological Process GO:0006695 cholesterol biosynthetic process
Biological Process GO:0033489 cholesterol biosynthetic process via desmosterol
Biological Process GO:0033490 cholesterol biosynthetic process via lathosterol
Biological Process GO:0030324 lung development
Biological Process GO:0035264 multicellular organism growth
Biological Process GO:0009791 post-embryonic development
Biological Process GO:0042127 regulation of cell population proliferation
Biological Process GO:0045540 regulation of cholesterol biosynthetic process
Biological Process GO:0016126 sterol biosynthetic process
molecular function GO:0047598 7-dehydrocholesterol reductase activity
molecular function GO:0050661 NADP binding
molecular function GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors
molecular function GO:0009918 sterol delta7 reductase activity
cellular component GO:0005829 cytosol
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0005789 endoplasmic reticulum membrane
cellular component GO:0030176 integral component of endoplasmic reticulum membrane
cellular component GO:0016020 membrane
cellular component GO:0005640 nuclear outer membrane
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-1655829 Regulation of cholesterol biosynthesis by SREBP (SREBF)
R-HSA-191273 Cholesterol biosynthesis
R-HSA-2426168 Activation of gene expression by SREBF (SREBP)
R-HSA-556833 Metabolism of lipids
R-HSA-6807047 Cholesterol biosynthesis via desmosterol
R-HSA-6807062 Cholesterol biosynthesis via lathosterol
R-HSA-8957322 Metabolism of steroids
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000768 BXGD000007 Congenital Abnormality Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0000772 BXGD000009 Multiple congenital anomalies Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0001807 BXGD000077 Aggressive behavior Behavior and Behavior Mechanisms
C0003492 BXGD000198 Aortic coarctation Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0004352 BXGD000269 Autistic Disorder Mental Disorders
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0004943 BXGD000297 Behcet Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Skin and Connective Tissue Diseases; Stomatognathic Diseases; Cardiovascular Diseases
C0005745 BXGD000331 Blepharoptosis Eye Diseases
C0005944 BXGD000355 Metabolic Bone Disorder Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0006157 BXGD000377 Breech Presentation Female Urogenital Diseases and Pregnancy Complications
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007222 BXGD000454 Cardiovascular Diseases Cardiovascular Diseases
C0008073 BXGD000518 Developmental Disabilities Mental Disorders
C0008149 BXGD000520 Chlamydia Infections Female Urogenital Diseases and Pregnancy Complications; Infections; Male Urogenital Diseases
C0008297 BXGD000522 Choanal Atresia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0008925 BXGD000575 Cleft Palate Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases
C0009081 BXGD000581 Congenital clubfoot Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0009806 BXGD000633 Constipation Pathological Conditions, Signs and Symptoms
C0010054 BXGD000647 Coronary Arteriosclerosis Cardiovascular Diseases
C0010068 BXGD000648 Coronary heart disease Cardiovascular Diseases
C0010417 BXGD000670 Cryptorchidism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Male Urogenital Diseases; Endocrine System Diseases
C0010964 BXGD000692 Dandy-Walker Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0011854 BXGD000753 Diabetes Mellitus, Insulin-Dependent Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0013274 BXGD000809 Patent ductus arteriosus Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0013336 BXGD000815 Dwarfism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases
C0013595 BXGD000858 Eczema Skin and Connective Tissue Diseases
C0015300 BXGD000973 Exophthalmos Eye Diseases
C0015544 BXGD001003 Failure to Thrive Pathological Conditions, Signs and Symptoms
C0015934 BXGD001026 Fetal Growth Retardation Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0017168 BXGD001101 Gastroesophageal reflux disease Digestive System Diseases
C0017601 BXGD001125 Glaucoma Eye Diseases
C0018784 BXGD001220 Sensorineural Hearing Loss (disorder) Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0018817 BXGD001235 Atrial Septal Defects Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0018818 BXGD001236 Ventricular Septal Defects Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0019569 BXGD001337 Hirschsprung Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases
C0020224 BXGD001366 Polyhydramnios Female Urogenital Diseases and Pregnancy Complications
C0020255 BXGD001369 Hydrocephalus Nervous System Diseases
C0020295 BXGD001372 Hydronephrosis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0020443 BXGD001385 Hypercholesterolemia Nutritional and Metabolic Diseases
C0020534 BXGD001421 Orbital separation excessive Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0020557 BXGD001432 Hypertriglyceridemia Nutritional and Metabolic Diseases
C0022821 BXGD001590 Kyphosis deformity of spine Musculoskeletal Diseases
C0023890 BXGD001713 Liver Cirrhosis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0024433 BXGD001771 Macrostomia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Stomatognathic Diseases
C0025362 BXGD001866 Mental Retardation Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0025517 BXGD001875 Metabolic Diseases Nutritional and Metabolic Diseases
C0025958 BXGD001882 Microcephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0025988 BXGD001883 Microglossia Stomatognathic Diseases
C0025990 BXGD001884 Micrognathism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases
C0025995 BXGD001885 Micromelia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0026106 BXGD001889 Mild Mental Retardation Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0026650 BXGD001913 Movement Disorders Nervous System Diseases
C0026697 BXGD001918 Mucolipidoses Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Musculoskeletal Diseases; Nervous System Diseases
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0026826 BXGD001935 Muscle Hypertonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0026827 BXGD001936 Muscle hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0027707 BXGD002024 Nephritis, Interstitial Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0028738 BXGD002081 Nystagmus Eye Diseases; Nervous System Diseases
C0029124 BXGD002113 Optic Atrophy Eye Diseases; Nervous System Diseases
C0029453 BXGD002154 Osteopenia Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0032460 BXGD002355 Polycystic Ovary Syndrome Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0033377 BXGD002406 Ptosis Pathological Conditions, Signs and Symptoms
C0034013 BXGD002450 Precocious Puberty Endocrine System Diseases
C0034194 BXGD002472 Pyloric Stenosis Digestive System Diseases
C0035579 BXGD002560 Rickets Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0036439 BXGD002615 Scoliosis, unspecified Musculoskeletal Diseases
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0036875 BXGD002640 Disorders of Sex Development Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0038379 BXGD002752 Strabismus Eye Diseases; Nervous System Diseases
C0040427 BXGD002864 Tooth Abnormalities Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Stomatognathic Diseases
C0040433 BXGD002865 Tooth Crowding Stomatognathic Diseases
C0040457 BXGD002867 Tooth, Supernumerary Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Stomatognathic Diseases
C0040583 BXGD002878 Tracheal Stenosis Respiratory Tract Diseases
C0041349 BXGD002920 Nephritis, Tubulointerstitial Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0042133 BXGD002960 Uterine Fibroids Neoplasms
C0042870 BXGD003008 Vitamin D Deficiency Nutritional and Metabolic Diseases
C0042963 BXGD003018 Vomiting Pathological Conditions, Signs and Symptoms
C0079541 BXGD003081 Holoprosencephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0079924 BXGD003103 Oligohydramnios Female Urogenital Diseases and Pregnancy Complications
C0085271 BXGD003148 Self-Injurious Behavior Behavior and Behavior Mechanisms
C0085584 BXGD003195 Encephalopathies Nervous System Diseases
C0086543 BXGD003294 Cataract Eye Diseases
C0151526 BXGD003432 Premature Birth Female Urogenital Diseases and Pregnancy Complications
C0151718 BXGD003464 Hypocholesterolemia Nutritional and Metabolic Diseases
C0152237 BXGD003569 Talipes Calcaneovalgus Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0152427 BXGD003590 Polydactyly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0156394 BXGD003856 Hypertrophy of clitoris Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0175694 BXGD004002 Smith-Lemli-Opitz Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0202117 BXGD004074 Low density lipoprotein cholesterol measurement
C0202236 BXGD004086 Triglycerides measurement
C0206762 BXGD004290 Limb Deformities, Congenital Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0221210 BXGD004406 Congenital malrotation of intestine Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases
C0221352 BXGD004444 Syndactyly of fingers Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Musculoskeletal Diseases
C0221357 BXGD004449 Brachydactyly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0221373 BXGD004454 Claw hand Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0231679 BXGD004507 Ulnar deviation of the fingers
C0235659 BXGD004763 Reduced fetal movement Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0235833 BXGD004775 Congenital diaphragmatic hernia Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0235991 BXGD004802 Small for gestational age (disorder) Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications
C0239234 BXGD004974 Low set ears
C0239676 BXGD004989 High forehead
C0239946 BXGD005010 Fibrosis, Liver Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0239998 BXGD005012 Recurrent infections Pathological Conditions, Signs and Symptoms; Infections; Musculoskeletal Diseases
C0240063 BXGD005015 Coloboma of iris Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0262586 BXGD005258 Osteopenia/osteoporosis Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0263401 BXGD005298 Cutis marmorata Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Skin and Connective Tissue Diseases; Cardiovascular Diseases; Wounds and Injuries
C0265267 BXGD005492 Congenital Hemidysplasia with Ichthyosiform Erythroderma and Limb Defects Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Musculoskeletal Diseases
C0265706 BXGD005570 Gastroschisis Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0265783 BXGD005575 Congenital hypoplasia of lung Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases
C0266054 BXGD005615 Premature tooth eruption
C0266111 BXGD005620 Bifid tongue Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0266249 BXGD005635 Gallbladder anomaly congenital Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases
C0266294 BXGD005644 Unilateral agenesis of kidney Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0266295 BXGD005645 Congenital hypoplasia of kidney Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0266313 BXGD005650 Allanson Pantzar McLeod syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0266362 BXGD005657 Ambiguous Genitalia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0266387 BXGD005661 Bicornuate uterus Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0266411 BXGD005664 Septate vagina Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0266435 BXGD005668 Congenital hypoplasia of penis Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0266551 BXGD005693 Congenital coloboma of iris Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0266642 BXGD005705 Situs ambiguus Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0268800 BXGD006041 Simple renal cyst Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0275524 BXGD006376 Coinfection Infections
C0282643 BXGD006822 Smith-Lemli-Opitz Syndrome, Type I Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0282644 BXGD006823 Smith-Lemli-Opitz Syndrome, Type II Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0302142 BXGD006831 Deformity Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0338502 BXGD007192 Hypoplasia of the optic nerve Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Nervous System Diseases
C0338656 BXGD007211 Impaired cognition Mental Disorders
C0341787 BXGD007422 Bifid scrotum
C0344482 BXGD007678 Hypoplasia of corpus callosum Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0349506 BXGD007912 Photosensitivity of skin Skin and Connective Tissue Diseases
C0349588 BXGD007933 Short stature
C0376480 BXGD007998 Gingival Overgrowth Stomatognathic Diseases
C0376634 BXGD008006 Craniofacial Abnormalities Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0392482 BXGD008048 Common atrium Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0392885 BXGD008071 High density lipoprotein measurement
C0398739 BXGD008223 Congenital disorder of glycosylation, type 2C Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0400966 BXGD008266 Non-alcoholic Fatty Liver Disease Digestive System Diseases
C0406740 BXGD008368 Kohlschutter Tonz syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders; Stomatognathic Diseases
C0423109 BXGD008470 Upward slant of palpebral fissure
C0423110 BXGD008471 Downward slant of palpebral fissure
C0424295 BXGD008524 Hyperactive behavior Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0424605 BXGD008535 Developmental delay (disorder) Mental Disorders
C0424731 BXGD008542 Single transverse palmar crease Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0428472 BXGD008630 Serum HDL cholesterol measurement
C0428474 BXGD008631 Serum LDL cholesterol measurement
C0431478 BXGD008692 Posteriorly rotated ear
C0431659 BXGD008699 Hypoplasia of scrotum
C0431890 BXGD008712 Hypoplasia of thumb Musculoskeletal Diseases
C0431904 BXGD008713 Ulnar polydactyly of fingers Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0432040 BXGD008715 Simple syndactyly of toes, first web space
C0432072 BXGD008718 Dysmorphic features
C0432333 BXGD008778 Abnormal dermatoglyphic pattern Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0521525 BXGD009139 Short neck
C0521619 BXGD009149 Obstruction of pelviureteric junction Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0524528 BXGD009229 Pervasive Development Disorder Mental Disorders
C0524910 BXGD009248 Hepatitis C, Chronic Digestive System Diseases; Infections
C0549306 BXGD009368 Mesomelia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Musculoskeletal Diseases
C0557874 BXGD009444 Global developmental delay
C0575897 BXGD009524 Thumb deformity Musculoskeletal Diseases
C0678230 BXGD009750 Congenital Epicanthus
C0685695 BXGD009813 Abnormal lung lobation Respiratory Tract Diseases
C0694563 BXGD009854 Excessive daytime somnolence
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0747085 BXGD010158 Recurrent otitis media Otorhinolaryngologic Diseases
C0848558 BXGD010882 Hypospadias Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0860204 BXGD011219 Cholestatic liver disease Digestive System Diseases
C0878787 BXGD011392 Growth failure
C0920299 BXGD011465 Overriding toe Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C1136179 BXGD011712 Hammer Toe Musculoskeletal Diseases
C1263846 BXGD011897 Attention deficit hyperactivity disorder Mental Disorders
C1302790 BXGD012313 Congenital malformation syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C1384666 BXGD012948 hearing impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C1386048 BXGD012950 Intrauterine retardation
C1387005 BXGD012953 Penis agenesis Male Urogenital Diseases
C1389016 BXGD012962 ATRIOVENTRICULAR CANAL DEFECT Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C1445957 BXGD013081 Serum total cholesterol measurement
C1510586 BXGD013176 Autism Spectrum Disorders Mental Disorders
C1531647 BXGD013301 Cerebral ventriculomegaly Nervous System Diseases
C1609433 BXGD013438 Congenital absence of kidneys syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1785148 BXGD013754 RAPP-HODGKIN SYNDROME Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Stomatognathic Diseases
C1827524 BXGD013773 Wide spaced nipples
C1833362 BXGD013919 Sleep-wake cycle disturbance
C1836047 BXGD014074 Long face
C1836195 BXGD014094 Short toe
C1836542 BXGD014129 Depressed nasal bridge
C1836923 BXGD014178 Gastrointestinal dysmotility
C1836940 BXGD014182 Thickened nuchal skin fold
C1837142 BXGD014201 Poor suck
C1839326 BXGD014367 Abnormal form of the vertebral bodies
C1839546 BXGD014385 Microretrognathia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases
C1839758 BXGD014402 Narrow forehead
C1840069 BXGD014433 Sandal gap
C1840077 BXGD014434 Anteverted nostril
C1842083 BXGD014494 Abnormality of the ribs
C1844573 BXGD014646 Large earlobe
C1844605 BXGD014651 Periorbital wrinkles
C1844731 BXGD014669 Hypoplastic nasal tip
C1846421 BXGD014811 Lathosterolosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C1849172 BXGD015019 Frontal lobe hypoplasia
C1849185 BXGD015020 Elevated 7-dehydrocholesterol
C1849186 BXGD015021 Severe photosensitivity Skin and Connective Tissue Diseases
C1849367 BXGD015046 Nasal bridge wide
C1849537 BXGD015063 Persistent open anterior fontanelle
C1853235 BXGD015318 Sclerocornea Eye Diseases
C1854114 BXGD015383 Short nose
C1854418 BXGD015402 Biparietal narrowing
C1857276 BXGD015688 Trichohepatoenteric Syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Skin and Connective Tissue Diseases
C1857278 BXGD015690 Partial or complete agenesis of corpus callosum
C1857453 BXGD015703 Renal hypoplasia/aplasia
C1857486 BXGD015710 Low-set, posteriorly rotated ears
C1857500 BXGD015711 Broad alveolar ridges
C1858120 BXGD015774 Generalized hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1858545 BXGD015804 Facial capillary hemangioma Neoplasms
C1859126 BXGD015854 Stippled epiphyses
C1861866 BXGD016087 Aplasia/Hypoplasia of the corpus callosum
C1865014 BXGD016282 Long philtrum
C1865572 BXGD016331 Proximal placement of thumb
C1865596 BXGD016332 Desmosterolosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C1866730 BXGD016419 Rhizomelia
C1868720 BXGD016531 Periventricular Nodular Heterotopia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C1956257 BXGD016623 Pulmonary Stenosis Cardiovascular Diseases
C1956346 BXGD016627 Coronary Artery Disease Cardiovascular Diseases
C1963184 BXGD016688 Nystagmus, CTCAE 3.0
C2112129 BXGD016921 Postaxial foot polydactyly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2674608 BXGD017250 Feeding difficulties in infancy
C2675111 BXGD017272 Abnormal eyelash morphology
C2677180 BXGD017366 Congenital microcephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C2711227 BXGD017478 Steatohepatitis Digestive System Diseases
C2713347 BXGD017495 7-Dehydrocholesterol Reductase Deficiency Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C2717836 BXGD017510 Steroid Sulfatase Deficiency Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C2720163 BXGD017530 Placental Steroid Sulfatase Deficiency Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C2749463 BXGD017620 Aplasia/Hypoplasia of the radius
C2751532 BXGD017722 3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 Deficiency Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C2919142 BXGD017867 Short Stature, CTCAE
C2931867 BXGD018084 Dandy Walker cyst Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C3266731 BXGD018602 2-methyl-3-hydroxybutyric aciduria Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C3278401 BXGD018739 Hypopigmentation of hair
C3278923 BXGD018748 Dilated ventricles (finding)
C3279222 BXGD018751 Aplasia/Hypoplasia of the cerebellum
C3281160 BXGD018885 EHLERS-DANLOS SYNDROME, KYPHOSCOLIOTIC TYPE, 2
C3495559 BXGD018994 Juvenile arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C3696376 BXGD019346 3-Methylglutaconic Aciduria Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C3714581 BXGD019415 Multicystic Dysplastic Kidney Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C3887499 BXGD019884 Renal cyst Pathological Conditions, Signs and Symptoms; Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C4020968 BXGD020516 Abnormal localization of kidney
C4021085 BXGD020544 Abnormality of brain morphology
C4021777 BXGD020773 Abnormality of the larynx
C4021785 BXGD020778 Abnormality of the metacarpal bones Musculoskeletal Diseases
C4021800 BXGD020790 Abnormality of dental enamel
C4023676 BXGD021237 Increased nuchal translucency Pathological Conditions, Signs and Symptoms
C4024202 BXGD021303 Reduced number of teeth
C4024745 BXGD021401 Aplasia/Hypoplasia affecting the eye
C4025158 BXGD021569 Rudimentary postaxial polydactyly of hands
C4082169 BXGD022084 Metatarsus Varus Musculoskeletal Diseases
C4266451 BXGD022319 Fetal abnormality
C4551570 BXGD023357 2-3 toe syndactyly
C4551905 BXGD023438 Pulmonary Venous Return Anomaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases; Cardiovascular Diseases
C4554036 BXGD023557 Nystagmus, CTCAE 5.0
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0013588 Epipachysamine D 450.36
BXGC0019621 (+)-Axillaridine A 462.32
BXGC0034783 Doxorubicin 543.17
BXGC0045938 (+)-(20S)-3-(Benzoylamino)-20-(Dimethylamino)-5Alpha-Pregn-2-En-4Beta-Yl Acetate 506.35
BXGC0045944 (+)-Spiropachysine 462.36
BXGC0045953 (+)-(20S)-20-(Dimethylamino)-3-(3'alpha-Isopropyl)-Lactam-5Alpha-Pregn-2-En-4-One 454.36
BXGC0045954 (+)-(20S)-20-(Dimethylamino)-16Alpha-Hydroxy-3-(3'alpha-Isopropyl)-La Ctam-5Alpha-Pregn-2-En-4-One 470.35
BXGC0046256 (+)-(20S)-2Alpha-Hydroxy-20-(Dimethylamino)-3Beta-Phthalimido-5 Alpha-Pregnan-4Beta-Yl Acetate 550.34
BXGC0050467 (-)-Pachyaximine A 359.32
BXGC0052527 (+)-Pachysamine B 442.39
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein