Showing entry for FATTY LIVER DISEASE, NONALCOHOLIC, SUSCEPTIBILITY TO, 2


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD018316
Disease NameFATTY LIVER DISEASE, NONALCOHOLIC, SUSCEPTIBILITY TO, 2
Disease CUI IdC3150651
MeSH Codes   
Disease Class Name
Semantic TypeFinding
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:0014667   DOID:630  
Disease Ontology Class Namedisease of metabolism; genetic disease
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O00264 BXGT003904 Membrane-associated progesterone receptor component 1 10857 reviewed Signaling
O14832 BXGT004104 Phytanoyl-CoA dioxygenase, peroxisomal 5264 reviewed
O15438 BXGT004168 Canalicular multispecific organic anion transporter 2 8714 reviewed Transporter
O60674 BXGT004892 Tyrosine-protein kinase JAK2 3717 reviewed Kinase
P00390 BXGT005526 Glutathione reductase, mitochondrial 2936 reviewed Enzyme
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P02452 BXGT005878 Collagen alpha-1(I) chain 1277 reviewed
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P02786 BXGT005961 Transferrin receptor protein 1 7037 reviewed Enzyme
P04035 BXGT006129 3-hydroxy-3-methylglutaryl-coenzyme A reductase 3156 reviewed
P05181 BXGT006337 Cytochrome P450 2E1 1571 reviewed
P06213 BXGT006425 Insulin receptor 3643 reviewed Kinase
P06858 BXGT006515 Lipoprotein lipase 4023 reviewed Enzyme
P08069 BXGT006723 Insulin-like growth factor 1 receptor 3480 reviewed Kinase
P08183 BXGT006741 ATP-dependent translocase ABCB1 5243 reviewed Transporter
P11413 BXGT007701 Glucose-6-phosphate 1-dehydrogenase 2539 reviewed Enzyme
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P13501 BXGT007917 C-C motif chemokine 5 6352 reviewed Signaling
P14735 BXGT008042 Insulin-degrading enzyme 3416 reviewed Enzyme
P15559 BXGT008139 NAD(P)H dehydrogenase [quinone] 1 1728 reviewed
P21399 BXGT008646 Cytoplasmic aconitate hydratase 48 reviewed Enzyme
P25705 BXGT009060 ATP synthase subunit alpha, mitochondrial 498 reviewed Transporter
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P45983 BXGT010494 Mitogen-activated protein kinase 8 5599 reviewed Kinase
P48357 BXGT010627 Leptin receptor 3953 reviewed Signaling
P49748 BXGT010733 Very long-chain specific acyl-CoA dehydrogenase, mitochondrial 37 reviewed Enzyme
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
P81172 BXGT011935 Hepcidin 57817 reviewed
Q12778 BXGT013263 Forkhead box protein O1 2308 reviewed
Q13133 BXGT013315 Oxysterols receptor LXR-alpha 10062 reviewed Nuclear receptor
Q14116 BXGT013442 Interleukin-18 3606 reviewed
Q15848 BXGT013609 Adiponectin 9370 reviewed
Q15910 BXGT013612 Histone-lysine N-methyltransferase EZH2 2146 reviewed Epigenetic regulator
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q76LX8 BXGT016870 A disintegrin and metalloproteinase with thrombospondin motifs 13 11093 reviewed Enzyme
Q8IXJ6 BXGT018362 NAD-dependent protein deacetylase sirtuin-2 22933 reviewed Epigenetic regulator
Q8N6T7 BXGT018525 NAD-dependent protein deacetylase sirtuin-6 51548 reviewed Epigenetic regulator
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 23411 reviewed Epigenetic regulator
Q96P20 BXGT019704 NACHT, LRR and PYD domains-containing protein 3 114548 reviewed
Q96RI1 BXGT019727 Bile acid receptor 9971 reviewed Nuclear receptor
Q9NTG7 BXGT021211 NAD-dependent protein deacetylase sirtuin-3, mitochondrial 23410 reviewed Epigenetic regulator
P00738 BXGT022874 Haptoglobin 3240 reviewed Enzyme
O95140 BXGT024482 Mitofusin-2 9927 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease