Showing entry for HEMOCHROMATOSIS, TYPE 1


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD018909
Disease NameHEMOCHROMATOSIS, TYPE 1
Disease CUI IdC3469186
MeSH Codes C16   C18  
Disease Class NameCongenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:0014667   DOID:630  
Disease Ontology Class Namedisease of metabolism; genetic disease
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O60760 BXGT004899 Hematopoietic prostaglandin D synthase 27306 reviewed
O95864 BXGT005403 Acyl-CoA 6-desaturase 9415 reviewed
P00441 BXGT005540 Superoxide dismutase [Cu-Zn] 6647 reviewed Enzyme
P00450 BXGT005544 Ceruloplasmin 1356 reviewed Enzyme
P01009 BXGT005714 Alpha-1-antitrypsin 5265 reviewed Enzyme modulator
P01148 BXGT005739 Progonadoliberin-1 2796 reviewed
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01889 BXGT005809 HLA class I histocompatibility antigen, B-7 alpha chain 3106 reviewed
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P02774 BXGT005959 Vitamin D-binding protein 2638 reviewed Transporter
P02786 BXGT005961 Transferrin receptor protein 1 7037 reviewed Enzyme
P02787 BXGT005962 Serotransferrin 7018 reviewed Enzyme
P02792 BXGT005966 Ferritin light chain 2512 reviewed Storage
P03956 BXGT006120 Interstitial collagenase 4312 reviewed Enzyme
P04406 BXGT006207 Glyceraldehyde-3-phosphate dehydrogenase 2597 reviewed Enzyme
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P05091 BXGT006312 Aldehyde dehydrogenase, mitochondrial 217 reviewed Enzyme
P05231 BXGT006345 Interleukin-6 3569 reviewed
P09211 BXGT006869 Glutathione S-transferase P 2950 reviewed
P12643 BXGT007830 Bone morphogenetic protein 2 650 reviewed Signaling
P13569 BXGT007923 Cystic fibrosis transmembrane conductance regulator 1080 reviewed Ion channel
P13716 BXGT007948 Delta-aminolevulinic acid dehydratase 210 reviewed Enzyme
P22004 BXGT008718 Bone morphogenetic protein 6 654 reviewed Signaling
P27797 BXGT009206 Calreticulin 811 reviewed Calcium-binding protein
P30556 BXGT009441 Type-1 angiotensin II receptor 185 reviewed G-protein coupled receptor
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P35858 BXGT009876 Insulin-like growth factor-binding protein complex acid labile subunit 3483 reviewed Receptor
P49281 BXGT010689 Natural resistance-associated macrophage protein 2 4891 reviewed Transporter
P49763 BXGT010737 Placenta growth factor 5228 reviewed Signaling
P51668 BXGT010875 Ubiquitin-conjugating enzyme E2 D1 7321 reviewed Enzyme
P61769 BXGT011383 Beta-2-microglobulin 567 reviewed Immune response
P81172 BXGT011935 Hepcidin 57817 reviewed
Q00987 BXGT012559 E3 ubiquitin-protein ligase Mdm2 4193 reviewed Nucleic acid binding
Q15848 BXGT013609 Adiponectin 9370 reviewed
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q16549 BXGT013637 Proprotein convertase subtilisin/kexin type 7 9159 reviewed
Q16595 BXGT013643 Frataxin, mitochondrial 2395 reviewed Enzyme
Q30201 BXGT014297 Hereditary hemochromatosis protein 3077 reviewed
Q53TN4 BXGT015019 Cytochrome b reductase 1 79901 reviewed Enzyme
Q6ZVN8 BXGT016641 Hemojuvelin 148738 reviewed
Q9BXA5 BXGT020163 Succinate receptor 1 56670 reviewed G-protein coupled receptor
P04439 BXGT022649 HLA class I histocompatibility antigen, A-3 alpha chain 3105 reviewed
P00738 BXGT022874 Haptoglobin 3240 reviewed Enzyme
P35670 BXGT023695 Copper-transporting ATPase 2 540 reviewed Transporter
Q99958 BXGT023732 Forkhead box protein C2 2303 reviewed Transcription factor
O15504 BXGT023763 Nucleoporin-like protein 2 11097 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease