adisease

Showing entry for Osteolysis

General Disease Information
BXGD Id	BXGD023735
Disease Name	Osteolysis
Disease CUI Id	C4721411
MeSH Codes	C05
Disease Class Name	Musculoskeletal Diseases
Semantic Type	Pathologic Function
Human Phenotype Ontology Id	HP:0000924
Human Phenotype Ontology Term	Abnormality of the skeletal system
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
A0A024RAV5	BXGT000013	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b	3845	unreviewed
O14788	BXGT004100	Tumor necrosis factor ligand superfamily member 11	8600	reviewed	Signaling
O43683	BXGT004614	Mitotic checkpoint serine/threonine-protein kinase BUB1	699	reviewed	Kinase
O60566	BXGT004884	Mitotic checkpoint serine/threonine-protein kinase BUB1 beta	701	reviewed	Kinase
O75874	BXGT005157	Isocitrate dehydrogenase [NADP] cytoplasmic	3417	reviewed
O96017	BXGT005415	Serine/threonine-protein kinase Chk2	11200	reviewed	Kinase
P01116	BXGT005733	GTPase KRas	3845	reviewed	Enzyme modulator
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01911	BXGT005816	HLA class II histocompatibility antigen, DRB1-15 beta chain	3123	reviewed	Immune response
P02461	BXGT005880	Collagen alpha-1(III) chain	1281	reviewed
P02545	BXGT005889	Prelamin-A/C	4000	reviewed
P04062	BXGT006140	Lysosomal acid glucosylceramidase	2629	reviewed
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P09619	BXGT006911	Platelet-derived growth factor receptor beta	5159	reviewed	Kinase
P09651	BXGT006913	Heterogeneous nuclear ribonucleoprotein A1	3178	reviewed
P11362	BXGT007693	Fibroblast growth factor receptor 1	2260	reviewed	Kinase
P11473	BXGT007709	Vitamin D3 receptor	7421	reviewed	Nuclear receptor
P15056	BXGT008075	Serine/threonine-protein kinase B-raf	673	reviewed	Kinase
P15428	BXGT008121	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	3248	reviewed
P22626	BXGT008787	Heterogeneous nuclear ribonucleoproteins A2/B1	3181	reviewed
P29033	BXGT009308	Gap junction beta-2 protein	2706	reviewed	Cell-cell junction
P35222	BXGT009799	Catenin beta-1	1499	reviewed
P43235	BXGT010368	Cathepsin K	1513	reviewed	Enzyme
P48735	BXGT010657	Isocitrate dehydrogenase [NADP], mitochondrial	3418	reviewed
P51684	BXGT010880	C-C chemokine receptor type 6	1235	reviewed	G-protein coupled receptor
P53634	BXGT011007	Dipeptidyl peptidase 1	1075	reviewed	Enzyme
P55072	BXGT011103	Transitional endoplasmic reticulum ATPase	7415	reviewed
P58335	BXGT011233	Anthrax toxin receptor 2	118429	reviewed	Receptor
Q03431	BXGT012714	Parathyroid hormone/parathyroid hormone-related peptide receptor	5745	reviewed	G-protein coupled receptor
Q04721	BXGT012777	Neurogenic locus notch homolog protein 2	4853	reviewed
Q13501	BXGT013365	Sequestosome-1	8878	reviewed
Q14108	BXGT013440	Lysosome membrane protein 2	950	reviewed	Receptor
Q8NET8	BXGT018557	Transient receptor potential cation channel subfamily V member 3	162514	reviewed	Ion channel
Q92959	BXGT019400	Solute carrier organic anion transporter family member 2A1	6578	reviewed	Transporter
Q9UM47	BXGT021772	Neurogenic locus notch homolog protein 3	4854	reviewed
Q9Y6K9	BXGT022333	NF-kappa-B essential modulator	8517	reviewed	Kinase
P25054	BXGT022961	Adenomatous polyposis coli protein	324	reviewed
Q96JJ3	BXGT024291	Engulfment and cell motility protein 2	63916	reviewed	Signaling

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}