Showing entry for Unconventional myosin-Ic


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT003886
Protein NameUnconventional myosin-Ic
Uniport IdO00159
GeneMYO1C
Gene Id4641
DomainIQ; Myosin_head; Myosin_TH1
Pfam PF00612   PF00063   PF06017  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007015 actin filament organization
Biological Process GO:0071346 cellular response to interferon-gamma
Biological Process GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis
Biological Process GO:0051028 mRNA transport
Biological Process GO:0030838 positive regulation of actin filament polymerization
Biological Process GO:0030335 positive regulation of cell migration
Biological Process GO:0038089 positive regulation of cell migration by vascular endothelial growth factor signaling pathway
Biological Process GO:1900078 positive regulation of cellular response to insulin stimulus
Biological Process GO:0045815 positive regulation of gene expression, epigenetic
Biological Process GO:0090314 positive regulation of protein targeting to membrane
Biological Process GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway
Biological Process GO:0006605 protein targeting
Biological Process GO:0006612 protein targeting to membrane
Biological Process GO:2000810 regulation of bicellular tight junction assembly
Biological Process GO:0030050 vesicle transport along actin filament
molecular function GO:0030898 actin-dependent ATPase activity
molecular function GO:0051015 actin filament binding
molecular function GO:0005524 ATP binding
molecular function GO:0005516 calmodulin binding
molecular function GO:0000146 microfilament motor activity
molecular function GO:0008022 protein C-terminus binding
molecular function GO:0017160 Ral GTPase binding
molecular function GO:0005102 signaling receptor binding
cellular component GO:0015629 actin cytoskeleton
cellular component GO:0009925 basal plasma membrane
cellular component GO:0005903 brush border
cellular component GO:0005737 cytoplasm
cellular component GO:0030659 cytoplasmic vesicle membrane
cellular component GO:0005829 cytosol
cellular component GO:0070062 extracellular exosome
cellular component GO:0031941 filamentous actin
cellular component GO:0016328 lateral plasma membrane
cellular component GO:0016020 membrane
cellular component GO:0045121 membrane raft
cellular component GO:0005902 microvillus
cellular component GO:0016604 nuclear body
cellular component GO:0005643 nuclear pore
cellular component GO:0005730 nucleolus
cellular component GO:0005654 nucleoplasm
cellular component GO:0045335 phagocytic vesicle
cellular component GO:0005886 plasma membrane
cellular component GO:0032587 ruffle membrane
cellular component GO:0060171 stereocilium membrane
cellular component GO:0016461 unconventional myosin complex
cellular component GO:0031982 vesicle
Reactome
Pathway Id Pathway Name
R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane
R-HSA-1643685 Disease
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-199991 Membrane Trafficking
R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis
R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation
R-HSA-5653656 Vesicle-mediated transport
R-HSA-5663205 Infectious disease
R-HSA-9658195 Leishmania infection
R-HSA-9664407 Parasite infection
R-HSA-9664417 Leishmania phagocytosis
R-HSA-9664422 FCGR3A-mediated phagocytosis
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0004238 BXGD000262 Atrial Fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0018784 BXGD001220 Sensorineural Hearing Loss (disorder) Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0023508 BXGD001675 White Blood Cell Count procedure
C0023893 BXGD001716 Liver Cirrhosis, Experimental Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0024636 BXGD001793 Malocclusion Stomatognathic Diseases
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0042834 BXGD003004 Vital capacity
C0235480 BXGD004751 Paroxysmal atrial fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0235989 BXGD004801 Renal interstitial fibrosis Female Urogenital Diseases and Pregnancy Complications; Skin and Connective Tissue Diseases; Male Urogenital Diseases
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0282612 BXGD006820 Prostatic Intraepithelial Neoplasias Neoplasms
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0452138 BXGD008831 Sensorineural hearing loss, bilateral Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0936223 BXGD011477 Metastatic Prostate Carcinoma Neoplasms; Male Urogenital Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1282496 BXGD012147 Metastasis from malignant tumor of prostate
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1852282 BXGD015269 DEAFNESS, AUTOSOMAL DOMINANT 1 (disorder) Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C1969372 BXGD016775 Tubulointerstitial fibrosis
C2585653 BXGD017139 Persistent atrial fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C3468561 BXGD018908 familial atrial fibrillation Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein