Showing entry for Metastasis from malignant tumor of prostate


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD012147
Disease NameMetastasis from malignant tumor of prostate
Disease CUI IdC1282496
MeSH Codes   
Disease Class Name
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
A0A024RAV5 BXGT000013 V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b 3845 unreviewed
O00159 BXGT003886 Unconventional myosin-Ic 4641 reviewed Cellular structure
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O14746 BXGT004091 Telomerase reverse transcriptase 7015 reviewed Enzyme
O15054 BXGT004121 Lysine-specific demethylase 6B 23135 reviewed Epigenetic regulator
O15439 BXGT004169 Multidrug resistance-associated protein 4 10257 reviewed Transporter
O43497 BXGT004596 Voltage-dependent T-type calcium channel subunit alpha-1G 8913 reviewed Ion channel
O60260 BXGT004864 E3 ubiquitin-protein ligase parkin 5071 reviewed Enzyme
O75311 BXGT005109 Glycine receptor subunit alpha-3 8001 reviewed Ion channel
O75385 BXGT005121 Serine/threonine-protein kinase ULK1 8408 reviewed Kinase
O94907 BXGT005340 Dickkopf-related protein 1 22943 reviewed
O96028 BXGT005417 Histone-lysine N-methyltransferase NSD2 7468 reviewed Epigenetic regulator
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P00749 BXGT005641 Urokinase-type plasminogen activator 5328 reviewed Enzyme
P01106 BXGT005730 Myc proto-oncogene protein 4609 reviewed Transcription factor
P01116 BXGT005733 GTPase KRas 3845 reviewed Enzyme modulator
P01133 BXGT005736 Pro-epidermal growth factor 1950 reviewed
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01148 BXGT005739 Progonadoliberin-1 2796 reviewed
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02751 BXGT005943 Fibronectin 2335 reviewed Signaling
P02766 BXGT005953 Transthyretin 7276 reviewed Transporter
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P02786 BXGT005961 Transferrin receptor protein 1 7037 reviewed Enzyme
P02818 BXGT005969 Osteocalcin 632 reviewed
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P03956 BXGT006120 Interstitial collagenase 4312 reviewed Enzyme
P04150 BXGT006154 Glucocorticoid receptor 2908 reviewed Nuclear receptor
P04278 BXGT006182 Sex hormone-binding globulin 6462 reviewed
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 2064 reviewed Kinase
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P04792 BXGT006264 Heat shock protein beta-1 3315 reviewed
P05093 BXGT006313 Steroid 17-alpha-hydroxylase/17,20 lyase 1586 reviewed
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05362 BXGT006350 Intercellular adhesion molecule 1 3383 reviewed
P06239 BXGT006427 Tyrosine-protein kinase Lck 3932 reviewed Kinase
P07225 BXGT006572 Vitamin K-dependent protein S 5627 reviewed
P07288 BXGT006591 Prostate-specific antigen 354 reviewed Enzyme
P07355 BXGT006609 Annexin A2 302 reviewed
P07550 BXGT006636 Beta-2 adrenergic receptor 154 reviewed G-protein coupled receptor
P07602 BXGT006646 Prosaposin 5660 reviewed
P07900 BXGT006696 Heat shock protein HSP 90-alpha 3320 reviewed Chaperone
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P08581 BXGT006794 Hepatocyte growth factor receptor 4233 reviewed Kinase
P08887 BXGT006835 Interleukin-6 receptor subunit alpha 3570 reviewed Signaling
P09038 BXGT006851 Fibroblast growth factor 2 2247 reviewed Signaling
P09429 BXGT006889 High mobility group protein B1 3146 reviewed Nucleic acid binding
P09466 BXGT006892 Glycodelin 5047 reviewed Enzyme
P09486 BXGT006897 SPARC 6678 reviewed Signaling
P09874 BXGT006934 Poly [ADP-ribose] polymerase 1 142 reviewed
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10275 BXGT007552 Androgen receptor 367 reviewed Nuclear receptor
P11021 BXGT007644 Endoplasmic reticulum chaperone BiP 3309 reviewed
P11308 BXGT007684 Transcriptional regulator ERG 2078 reviewed Transcription factor
P11388 BXGT007697 DNA topoisomerase 2-alpha 7153 reviewed
P11511 BXGT007717 Aromatase 1588 reviewed Enzyme
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P13726 BXGT007950 Tissue factor 2152 reviewed Receptor
P14060 BXGT007978 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 3283 reviewed Enzyme
P14210 BXGT007994 Hepatocyte growth factor 3082 reviewed Enzyme
P14416 BXGT008011 D(2) dopamine receptor 1813 reviewed G-protein coupled receptor
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P15309 BXGT008105 Prostatic acid phosphatase 55 reviewed Enzyme
P15531 BXGT008136 Nucleoside diphosphate kinase A 4830 reviewed Kinase
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P15941 BXGT008176 Mucin-1 4582 reviewed
P16070 BXGT008186 CD44 antigen 960 reviewed
P18075 BXGT008375 Bone morphogenetic protein 7 655 reviewed Signaling
P18405 BXGT008400 3-oxo-5-alpha-steroid 4-dehydrogenase 1 6715 reviewed Enzyme
P18827 BXGT008427 Syndecan-1 6382 reviewed Extracellular structure
P21802 BXGT008691 Fibroblast growth factor receptor 2 2263 reviewed Kinase
P22004 BXGT008718 Bone morphogenetic protein 6 654 reviewed Signaling
P22392 BXGT008762 Nucleoside diphosphate kinase B 654364 reviewed Kinase
P23458 BXGT008868 Tyrosine-protein kinase JAK1 3716 reviewed Kinase
P24941 BXGT009002 Cyclin-dependent kinase 2 1017 reviewed Kinase
P25101 BXGT009018 Endothelin-1 receptor 1909 reviewed G-protein coupled receptor
P26447 BXGT009114 Protein S100-A4 6275 reviewed Calcium-binding protein
P27487 BXGT009187 Dipeptidyl peptidase 4 1803 reviewed Enzyme
P30086 BXGT009400 Phosphatidylethanolamine-binding protein 1 5037 reviewed Enzyme modulator
P30153 BXGT009409 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform 5518 reviewed Enzyme
P31213 BXGT009515 3-oxo-5-alpha-steroid 4-dehydrogenase 2 6716 reviewed Enzyme
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P35030 BXGT009784 Trypsin-3 5646 reviewed Enzyme
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35613 BXGT009856 Basigin 682 reviewed
P35869 BXGT009877 Aryl hydrocarbon receptor 196 reviewed Transcription factor
P36955 BXGT009946 Pigment epithelium-derived factor 5176 reviewed Enzyme modulator
P37173 BXGT009970 TGF-beta receptor type-2 7048 reviewed Kinase
P38398 BXGT010037 Breast cancer type 1 susceptibility protein 672 reviewed Enzyme
P38936 BXGT010074 Cyclin-dependent kinase inhibitor 1 1026 reviewed
P42226 BXGT010288 Signal transducer and activator of transcription 6 6778 reviewed Nucleic acid binding
P42330 BXGT010301 Aldo-keto reductase family 1 member C3 8644 reviewed Enzyme
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P42574 BXGT010317 Caspase-3 836 reviewed Enzyme
P43405 BXGT010386 Tyrosine-protein kinase SYK 6850 reviewed Kinase
P45983 BXGT010494 Mitogen-activated protein kinase 8 5599 reviewed Kinase
P46531 BXGT010526 Neurogenic locus notch homolog protein 1 4851 reviewed
P48060 BXGT010615 Glioma pathogenesis-related protein 1 11010 reviewed Immune response
P48061 BXGT010616 Stromal cell-derived factor 1 6387 reviewed
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P49711 BXGT010728 Transcriptional repressor CTCF 10664 reviewed Transcription factor
P49767 BXGT010739 Vascular endothelial growth factor C 7424 reviewed Signaling
P49841 BXGT010750 Glycogen synthase kinase-3 beta 2932 reviewed Kinase
P50281 BXGT010788 Matrix metalloproteinase-14 4323 reviewed Enzyme
P51681 BXGT010878 C-C chemokine receptor type 5 1234 reviewed G-protein coupled receptor
P52701 BXGT010943 DNA mismatch repair protein Msh6 2956 reviewed Nucleic acid binding
P54132 BXGT011032 Bloom syndrome protein 641 reviewed
P54278 BXGT011038 Mismatch repair endonuclease PMS2 5395 reviewed Nucleic acid binding
P55786 BXGT011125 Puromycin-sensitive aminopeptidase 9520 reviewed Enzyme
P56945 BXGT011206 Breast cancer anti-estrogen resistance protein 1 9564 reviewed
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P60568 BXGT011315 Interleukin-2 3558 reviewed
P61073 BXGT011352 C-X-C chemokine receptor type 4 7852 reviewed G-protein coupled receptor
P62136 BXGT011407 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit 5499 reviewed Enzyme
P63279 BXGT011514 SUMO-conjugating enzyme UBC9 7329 reviewed
P68104 BXGT011575 Elongation factor 1-alpha 1 1915 reviewed Enzyme
P78380 BXGT011841 Oxidized low-density lipoprotein receptor 1 4973 reviewed
P98160 BXGT012228 Basement membrane-specific heparan sulfate proteoglycan core protein 3339 reviewed Enzyme modulator
Q00535 BXGT012534 Cyclin-dependent-like kinase 5 1020 reviewed Kinase
Q04609 BXGT012768 Glutamate carboxypeptidase 2 2346 reviewed Enzyme
Q05823 BXGT012840 2-5A-dependent ribonuclease 6041 reviewed Kinase
Q06828 BXGT012893 Fibromodulin 2331 reviewed
Q07011 BXGT012912 Tumor necrosis factor receptor superfamily member 9 3604 reviewed
Q12931 BXGT013282 Heat shock protein 75 kDa, mitochondrial 10131 reviewed Chaperone
Q12965 BXGT013285 Unconventional myosin-Ie 4643 reviewed Cellular structure
Q13163 BXGT013321 Dual specificity mitogen-activated protein kinase kinase 5 5607 reviewed Kinase
Q13315 BXGT013339 Serine-protein kinase ATM 472 reviewed Kinase
Q13363 BXGT013344 C-terminal-binding protein 1 1487 reviewed Transcription factor
Q13478 BXGT013362 Interleukin-18 receptor 1 8809 reviewed Receptor
Q13501 BXGT013365 Sequestosome-1 8878 reviewed
Q13510 BXGT013367 Acid ceramidase 427 reviewed Enzyme
Q14393 BXGT013466 Growth arrest-specific protein 6 2621 reviewed Extracellular structure
Q14457 BXGT013472 Beclin-1 8678 reviewed Enzyme modulator
Q14683 BXGT013500 Structural maintenance of chromosomes protein 1A 8243 reviewed
Q14749 BXGT013503 Glycine N-methyltransferase 27232 reviewed
Q15022 BXGT013523 Polycomb protein SUZ12 23512 reviewed Nucleic acid binding
Q15257 BXGT013554 Serine/threonine-protein phosphatase 2A activator 5524 reviewed Enzyme modulator
Q15366 BXGT013559 Poly(rC)-binding protein 2 5094 reviewed Enzyme
Q15910 BXGT013612 Histone-lysine N-methyltransferase EZH2 2146 reviewed Epigenetic regulator
Q16512 BXGT013631 Serine/threonine-protein kinase N1 5585 reviewed Kinase
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q16678 BXGT013656 Cytochrome P450 1B1 1545 reviewed Enzyme
Q460N5 BXGT014635 Protein mono-ADP-ribosyltransferase PARP14 54625 reviewed
Q7Z2W7 BXGT017248 Transient receptor potential cation channel subfamily M member 8 79054 reviewed Ion channel
Q86YC2 BXGT017633 Partner and localizer of BRCA2 79728 reviewed
Q8TC12 BXGT018793 Retinol dehydrogenase 11 51109 reviewed Enzyme
Q8TDB6 BXGT018807 E3 ubiquitin-protein ligase DTX3L 151636 reviewed Enzyme
Q8TDQ0 BXGT018810 Hepatitis A virus cellular receptor 2 84868 reviewed
Q92731 BXGT019366 Estrogen receptor beta 2100 reviewed Nuclear receptor
Q969G3 BXGT019607 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 6605 reviewed
Q969I3 BXGT019609 Glycine N-acyltransferase-like protein 1 92292 reviewed
Q96GD4 BXGT019667 Aurora kinase B 9212 reviewed Kinase
Q99683 BXGT019947 Mitogen-activated protein kinase kinase kinase 5 4217 reviewed Kinase
Q99755 BXGT019958 Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha 8394 reviewed Kinase
Q9BUZ4 BXGT020139 TNF receptor-associated factor 4 9618 reviewed Signaling
Q9H7Z6 BXGT020493 Histone acetyltransferase KAT8 84148 reviewed
Q9H8P0 BXGT020497 Polyprenol reductase 79644 reviewed
Q9HAS3 BXGT020507 Solute carrier family 28 member 3 64078 reviewed Transporter
Q9NTG7 BXGT021211 NAD-dependent protein deacetylase sirtuin-3, mitochondrial 23410 reviewed Epigenetic regulator
Q9NYV4 BXGT021262 Cyclin-dependent kinase 12 51755 reviewed Kinase
Q9NZQ7 BXGT021281 Programmed cell death 1 ligand 1 29126 reviewed Receptor
Q9P0U3 BXGT021292 Sentrin-specific protease 1 29843 reviewed Enzyme
Q9UBK8 BXGT021655 Methionine synthase reductase 4552 reviewed
Q9UBN7 BXGT021658 Histone deacetylase 6 10013 reviewed Epigenetic regulator
Q9UQ80 BXGT021806 Proliferation-associated protein 2G4 5036 reviewed
Q9Y4K1 BXGT022281 Beta/gamma crystallin domain-containing protein 1 202 reviewed
Q9Y5K2 BXGT022293 Kallikrein-4 9622 reviewed Enzyme
Q9Y617 BXGT022314 Phosphoserine aminotransferase 29968 reviewed
P35232 BXGT022663 Prohibitin 5245 reviewed
Q13330 BXGT023103 Metastasis-associated protein MTA1 9112 reviewed Nucleic acid binding
P53539 BXGT023438 Protein fosB 2354 reviewed Transcription factor
O60232 BXGT024169 Protein ZNRD2 10534 reviewed
P20809 BXGT025043 Interleukin-11 3589 reviewed
P33993 BXGT025970 DNA replication licensing factor MCM7 4176 reviewed Enzyme
Q9UHE8 BXGT025995 Metalloreductase STEAP1 26872 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease