Showing entry for Renal interstitial fibrosis


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD004801
Disease NameRenal interstitial fibrosis
Disease CUI IdC0235989
MeSH Codes C13   C17   C12  
Disease Class NameFemale Urogenital Diseases and Pregnancy Complications; Skin and Connective Tissue Diseases; Male Urogenital Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00159 BXGT003886 Unconventional myosin-Ic 4641 reviewed Cellular structure
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O43318 BXGT004586 Mitogen-activated protein kinase kinase kinase 7 6885 reviewed Kinase
O75469 BXGT005128 Nuclear receptor subfamily 1 group I member 2 8856 reviewed Nuclear receptor
P00747 BXGT005639 Plasminogen 5340 reviewed Enzyme
P00750 BXGT005642 Tissue-type plasminogen activator 5327 reviewed Enzyme
P01019 BXGT005717 Angiotensinogen 183 reviewed Enzyme modulator
P01024 BXGT005719 Complement C3 718 reviewed Enzyme modulator
P01034 BXGT005721 Cystatin-C 1471 reviewed
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01583 BXGT005771 Interleukin-1 alpha 3552 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P02751 BXGT005943 Fibronectin 2335 reviewed Signaling
P04264 BXGT006176 Keratin, type II cytoskeletal 1 3848 reviewed
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P05121 BXGT006320 Plasminogen activator inhibitor 1 5054 reviewed Enzyme modulator
P05231 BXGT006345 Interleukin-6 3569 reviewed
P07438 BXGT006625 Metallothionein-1B 4490 reviewed
P07996 BXGT006710 Thrombospondin-1 7057 reviewed
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P08670 BXGT006810 Vimentin 7431 reviewed
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10599 BXGT007583 Thioredoxin 7295 reviewed
P12643 BXGT007830 Bone morphogenetic protein 2 650 reviewed Signaling
P12830 BXGT007852 Cadherin-1 999 reviewed
P13501 BXGT007917 C-C motif chemokine 5 6352 reviewed Signaling
P14210 BXGT007994 Hepatocyte growth factor 3082 reviewed Enzyme
P14618 BXGT008027 Pyruvate kinase PKM 5315 reviewed Kinase
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P15090 BXGT008079 Fatty acid-binding protein, adipocyte 2167 reviewed
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P18146 BXGT008384 Early growth response protein 1 1958 reviewed Nucleic acid binding
P19883 BXGT008528 Follistatin 10468 reviewed Enzyme modulator
P25116 BXGT009025 Proteinase-activated receptor 1 2149 reviewed G-protein coupled receptor
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P29274 BXGT009327 Adenosine receptor A2a 135 reviewed G-protein coupled receptor
P29323 BXGT009334 Ephrin type-B receptor 2 2048 reviewed Kinase
P30405 BXGT009423 Peptidyl-prolyl cis-trans isomerase F, mitochondrial 10105 reviewed
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P35610 BXGT009855 Sterol O-acyltransferase 1 6646 reviewed Enzyme
P38936 BXGT010074 Cyclin-dependent kinase inhibitor 1 1026 reviewed
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P45983 BXGT010494 Mitogen-activated protein kinase 8 5599 reviewed Kinase
P46531 BXGT010526 Neurogenic locus notch homolog protein 1 4851 reviewed
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P49116 BXGT010678 Nuclear receptor subfamily 2 group C member 2 7182 reviewed Nuclear receptor
P49767 BXGT010739 Vascular endothelial growth factor C 7424 reviewed Signaling
P50052 BXGT010768 Type-2 angiotensin II receptor 186 reviewed G-protein coupled receptor
P51681 BXGT010878 C-C chemokine receptor type 5 1234 reviewed G-protein coupled receptor
P55157 BXGT011108 Microsomal triglyceride transfer protein large subunit 4547 reviewed Transporter
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
P84022 BXGT012027 Mothers against decapentaplegic homolog 3 4088 reviewed Transcription factor
P98164 BXGT012230 Low-density lipoprotein receptor-related protein 2 4036 reviewed
Q13418 BXGT013351 Integrin-linked protein kinase 3611 reviewed Kinase
Q14116 BXGT013442 Interleukin-18 3606 reviewed
Q15796 BXGT013599 Mothers against decapentaplegic homolog 2 4087 reviewed Transcription factor
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q16772 BXGT013666 Glutathione S-transferase A3 2940 reviewed
Q16832 BXGT013678 Discoidin domain-containing receptor 2 4921 reviewed Kinase
Q5NUL3 BXGT015621 Free fatty acid receptor 4 338557 reviewed
Q96D42 BXGT019636 Hepatitis A virus cellular receptor 1 26762 reviewed
Q99538 BXGT019931 Legumain 5641 reviewed Enzyme
Q99683 BXGT019947 Mitogen-activated protein kinase kinase kinase 5 4217 reviewed Kinase
Q99836 BXGT019970 Myeloid differentiation primary response protein MyD88 4615 reviewed Enzyme modulator
Q9HC29 BXGT020526 Nucleotide-binding oligomerization domain-containing protein 2 64127 reviewed Enzyme
Q9UHI8 BXGT021701 A disintegrin and metalloproteinase with thrombospondin motifs 1 9510 reviewed Enzyme
Q9Y239 BXGT022213 Nucleotide-binding oligomerization domain-containing protein 1 10392 reviewed Enzyme
Q16552 BXGT023419 Interleukin-17A 3605 reviewed
Q9BYC5 BXGT025656 Alpha-(1,6)-fucosyltransferase 2530 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease