Showing entry for Prostatic Intraepithelial Neoplasias


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD006820
Disease NameProstatic Intraepithelial Neoplasias
Disease CUI IdC0282612
MeSH Codes C04  
Disease Class NameNeoplasms
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00141 BXGT003882 Serine/threonine-protein kinase Sgk1 6446 reviewed Kinase
O00159 BXGT003886 Unconventional myosin-Ic 4641 reviewed Cellular structure
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O00472 BXGT003927 RNA polymerase II elongation factor ELL2 22936 reviewed Cell-cell junction
O14965 BXGT004117 Aurora kinase A 6790 reviewed Kinase
O60760 BXGT004899 Hematopoietic prostaglandin D synthase 27306 reviewed
O75164 BXGT005104 Lysine-specific demethylase 4A 9682 reviewed
O75387 BXGT005122 Large neutral amino acids transporter small subunit 3 8501 reviewed Transporter
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P00749 BXGT005641 Urokinase-type plasminogen activator 5328 reviewed Enzyme
P01034 BXGT005721 Cystatin-C 1471 reviewed
P01106 BXGT005730 Myc proto-oncogene protein 4609 reviewed Transcription factor
P02533 BXGT005887 Keratin, type I cytoskeletal 14 3861 reviewed
P02545 BXGT005889 Prelamin-A/C 4000 reviewed
P02795 BXGT005968 Metallothionein-2 4502 reviewed
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P03950 BXGT006116 Angiogenin 283 reviewed
P03956 BXGT006120 Interstitial collagenase 4312 reviewed Enzyme
P04083 BXGT006147 Annexin A1 301 reviewed
P04271 BXGT006177 Protein S100-B 6285 reviewed Calcium-binding protein
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 2064 reviewed Kinase
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P05109 BXGT006318 Protein S100-A8 6279 reviewed Calcium-binding protein
P05154 BXGT006327 Plasma serine protease inhibitor 5104 reviewed Enzyme modulator
P05787 BXGT006385 Keratin, type II cytoskeletal 8 3856 reviewed
P06241 BXGT006429 Tyrosine-protein kinase Fyn 2534 reviewed Kinase
P06454 BXGT006441 Prothymosin alpha 5757 reviewed
P06702 BXGT006476 Protein S100-A9 6280 reviewed Calcium-binding protein
P06731 BXGT006488 Carcinoembryonic antigen-related cell adhesion molecule 5 1048 reviewed
P07225 BXGT006572 Vitamin K-dependent protein S 5627 reviewed
P07288 BXGT006591 Prostate-specific antigen 354 reviewed Enzyme
P07355 BXGT006609 Annexin A2 302 reviewed
P07741 BXGT006666 Adenine phosphoribosyltransferase 353 reviewed
P07900 BXGT006696 Heat shock protein HSP 90-alpha 3320 reviewed Chaperone
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P08263 BXGT006759 Glutathione S-transferase A1 2938 reviewed
P08473 BXGT006773 Neprilysin 4311 reviewed Enzyme
P08581 BXGT006794 Hepatocyte growth factor receptor 4233 reviewed Kinase
P08670 BXGT006810 Vimentin 7431 reviewed
P09211 BXGT006869 Glutathione S-transferase P 2950 reviewed
P09237 BXGT006874 Matrilysin 4316 reviewed Enzyme
P09601 BXGT006909 Heme oxygenase 1 3162 reviewed
P10275 BXGT007552 Androgen receptor 367 reviewed Nuclear receptor
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10826 BXGT007622 Retinoic acid receptor beta 5915 reviewed Nuclear receptor
P10909 BXGT007630 Clusterin 1191 reviewed
P11308 BXGT007684 Transcriptional regulator ERG 2078 reviewed Transcription factor
P11309 BXGT007685 Serine/threonine-protein kinase pim-1 5292 reviewed Kinase
P12830 BXGT007852 Cadherin-1 999 reviewed
P13688 BXGT007943 Carcinoembryonic antigen-related cell adhesion molecule 1 634 reviewed
P14210 BXGT007994 Hepatocyte growth factor 3082 reviewed Enzyme
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P15311 BXGT008106 Ezrin 7430 reviewed Cellular structure
P15531 BXGT008136 Nucleoside diphosphate kinase A 4830 reviewed Kinase
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P16050 BXGT008184 Arachidonate 15-lipoxygenase 246 reviewed Enzyme
P16455 BXGT008229 Methylated-DNA--protein-cysteine methyltransferase 4255 reviewed
P17936 BXGT008357 Insulin-like growth factor-binding protein 3 3486 reviewed Enzyme modulator
P17948 BXGT008358 Vascular endothelial growth factor receptor 1 2321 reviewed Kinase
P18054 BXGT008370 Arachidonate 12-lipoxygenase, 12S-type 239 reviewed Enzyme
P18847 BXGT008431 Cyclic AMP-dependent transcription factor ATF-3 467 reviewed Transcription factor
P19793 BXGT008515 Retinoic acid receptor RXR-alpha 6256 reviewed Nuclear receptor
P21579 BXGT008665 Synaptotagmin-1 6857 reviewed Transporter
P21860 BXGT008698 Receptor tyrosine-protein kinase erbB-3 2065 reviewed Kinase
P22413 BXGT008764 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 5167 reviewed Enzyme
P22897 BXGT008816 Macrophage mannose receptor 1 4360 reviewed
P23297 BXGT008848 Protein S100-A1 6271 reviewed Calcium-binding protein
P24385 BXGT008965 G1/S-specific cyclin-D1 595 reviewed Enzyme modulator
P24593 BXGT008979 Insulin-like growth factor-binding protein 5 3488 reviewed Enzyme modulator
P26358 BXGT009104 DNA (cytosine-5)-methyltransferase 1 1786 reviewed Epigenetic regulator
P28562 BXGT009270 Dual specificity protein phosphatase 1 1843 reviewed
P30536 BXGT009435 Translocator protein 706 reviewed
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35790 BXGT009866 Choline kinase alpha 1119 reviewed Kinase
P41143 BXGT010223 Delta-type opioid receptor 4985 reviewed G-protein coupled receptor
P42226 BXGT010288 Signal transducer and activator of transcription 6 6778 reviewed Nucleic acid binding
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P43235 BXGT010368 Cathepsin K 1513 reviewed Enzyme
P46527 BXGT010525 Cyclin-dependent kinase inhibitor 1B 1027 reviewed
P48060 BXGT010615 Glioma pathogenesis-related protein 1 11010 reviewed Immune response
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P49116 BXGT010678 Nuclear receptor subfamily 2 group C member 2 7182 reviewed Nuclear receptor
P49327 BXGT010694 Fatty acid synthase 2194 reviewed Enzyme
P50281 BXGT010788 Matrix metalloproteinase-14 4323 reviewed Enzyme
P51813 BXGT010894 Cytoplasmic tyrosine-protein kinase BMX 660 reviewed Kinase
P53350 BXGT010984 Serine/threonine-protein kinase PLK1 5347 reviewed Kinase
P54278 BXGT011038 Mismatch repair endonuclease PMS2 5395 reviewed Nucleic acid binding
P55786 BXGT011125 Puromycin-sensitive aminopeptidase 9520 reviewed Enzyme
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
Q01105 BXGT012569 Protein SET 6418 reviewed Enzyme modulator
Q02880 BXGT012677 DNA topoisomerase 2-beta 7155 reviewed
Q03405 BXGT012713 Urokinase plasminogen activator surface receptor 5329 reviewed
Q04206 BXGT012754 Transcription factor p65 5970 reviewed Transcription factor
Q05397 BXGT012815 Focal adhesion kinase 1 5747 reviewed Kinase
Q12931 BXGT013282 Heat shock protein 75 kDa, mitochondrial 10131 reviewed Chaperone
Q12965 BXGT013285 Unconventional myosin-Ie 4643 reviewed Cellular structure
Q13526 BXGT013369 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 5300 reviewed
Q13547 BXGT013373 Histone deacetylase 1 3065 reviewed Epigenetic regulator
Q15109 BXGT013537 Advanced glycosylation end product-specific receptor 177 reviewed Receptor
Q15796 BXGT013599 Mothers against decapentaplegic homolog 2 4087 reviewed Transcription factor
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q8TD43 BXGT018806 Transient receptor potential cation channel subfamily M member 4 54795 reviewed Ion channel
Q92731 BXGT019366 Estrogen receptor beta 2100 reviewed Nuclear receptor
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 23411 reviewed Epigenetic regulator
Q96Q83 BXGT019715 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 221120 reviewed
Q99828 BXGT019967 Calcium and integrin-binding protein 1 10519 reviewed
Q9BYW2 BXGT020192 Histone-lysine N-methyltransferase SETD2 29072 reviewed Epigenetic regulator
Q9BZS1 BXGT020203 Forkhead box protein P3 50943 reviewed
Q9H4A3 BXGT020473 Serine/threonine-protein kinase WNK1 65125 reviewed Kinase
Q9NP79 BXGT021145 Vacuolar protein sorting-associated protein VTA1 homolog 51534 reviewed
Q9NWM0 BXGT021232 Spermine oxidase 54498 reviewed
Q9P0U3 BXGT021292 Sentrin-specific protease 1 29843 reviewed Enzyme
Q9UKV8 BXGT021752 Protein argonaute-2 27161 reviewed
Q9Y237 BXGT022212 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 5303 reviewed
Q9Y5K2 BXGT022293 Kallikrein-4 9622 reviewed Enzyme
Q9Y617 BXGT022314 Phosphoserine aminotransferase 29968 reviewed
P19235 BXGT022895 Erythropoietin receptor 2057 reviewed Receptor
Q13330 BXGT023103 Metastasis-associated protein MTA1 9112 reviewed Nucleic acid binding
Q9BQQ3 BXGT024065 Golgi reassembly-stacking protein 1 64689 reviewed
P63167 BXGT024120 Dynein light chain 1, cytoplasmic 8655 reviewed Cellular structure
O60232 BXGT024169 Protein ZNRD2 10534 reviewed
P33993 BXGT025970 DNA replication licensing factor MCM7 4176 reviewed Enzyme
P00403 BXGT026137 Cytochrome c oxidase subunit 2 4513 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease