adisease

Showing entry for Malocclusion

General Disease Information
BXGD Id	BXGD001793
Disease Name	Malocclusion
Disease CUI Id	C0024636
MeSH Codes	C07
Disease Class Name	Stomatognathic Diseases
Semantic Type	Anatomical Abnormality
Human Phenotype Ontology Id	HP:0000152
Human Phenotype Ontology Term	Abnormality of head or neck
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00159	BXGT003886	Unconventional myosin-Ic	4641	reviewed	Cellular structure
O00522	BXGT003935	Krev interaction trapped protein 1	889	reviewed
O15550	BXGT004179	Lysine-specific demethylase 6A	7403	reviewed	Epigenetic regulator
O75147	BXGT005102	Obscurin-like protein 1	23363	reviewed
O75469	BXGT005128	Nuclear receptor subfamily 1 group I member 2	8856	reviewed	Nuclear receptor
P00918	BXGT005690	Carbonic anhydrase 2	760	reviewed
P01589	BXGT005773	Interleukin-2 receptor subunit alpha	3559	reviewed	Receptor
P02452	BXGT005878	Collagen alpha-1(I) chain	1277	reviewed
P02458	BXGT005879	Collagen alpha-1(II) chain	1280	reviewed
P04150	BXGT006154	Glucocorticoid receptor	2908	reviewed	Nuclear receptor
P08069	BXGT006723	Insulin-like growth factor 1 receptor	3480	reviewed	Kinase
P08754	BXGT006820	Guanine nucleotide-binding protein G(i) subunit alpha	2773	reviewed	Enzyme modulator
P0DP23	BXGT007520	Calmodulin-1	808	reviewed
P0DP24	BXGT007521	Calmodulin-2	808	reviewed
P10070	BXGT007534	Zinc finger protein GLI2	2736	reviewed
P10644	BXGT007597	cAMP-dependent protein kinase type I-alpha regulatory subunit	5573	reviewed
P12830	BXGT007852	Cadherin-1	999	reviewed
P14784	BXGT008054	Interleukin-2 receptor subunit beta	3560	reviewed	Receptor
P15056	BXGT008075	Serine/threonine-protein kinase B-raf	673	reviewed	Kinase
P17706	BXGT008330	Tyrosine-protein phosphatase non-receptor type 2	5771	reviewed
P17936	BXGT008357	Insulin-like growth factor-binding protein 3	3486	reviewed	Enzyme modulator
P18146	BXGT008384	Early growth response protein 1	1958	reviewed	Nucleic acid binding
P21333	BXGT008638	Filamin-A	2316	reviewed
P21802	BXGT008691	Fibroblast growth factor receptor 2	2263	reviewed	Kinase
P22607	BXGT008784	Fibroblast growth factor receptor 3	2261	reviewed	Kinase
P27482	BXGT009185	Calmodulin-like protein 3	810	reviewed	Calcium-binding protein
P27708	BXGT009202	CAD protein	790	reviewed	Enzyme
P27986	BXGT009216	Phosphatidylinositol 3-kinase regulatory subunit alpha	5295	reviewed	Kinase
P29033	BXGT009308	Gap junction beta-2 protein	2706	reviewed	Cell-cell junction
P35372	BXGT009823	Mu-type opioid receptor	4988	reviewed	G-protein coupled receptor
P38398	BXGT010037	Breast cancer type 1 susceptibility protein	672	reviewed	Enzyme
P49585	BXGT010712	Choline-phosphate cytidylyltransferase A	5130	reviewed
P51812	BXGT010893	Ribosomal protein S6 kinase alpha-3	6197	reviewed	Kinase
P53667	BXGT011008	LIM domain kinase 1	3984	reviewed	Kinase
P56524	BXGT011176	Histone deacetylase 4	9759	reviewed	Epigenetic regulator
P60953	BXGT011342	Cell division control protein 42 homolog	998	reviewed	Enzyme modulator
P84022	BXGT012027	Mothers against decapentaplegic homolog 3	4088	reviewed	Transcription factor
P98160	BXGT012228	Basement membrane-specific heparan sulfate proteoglycan core protein	3339	reviewed	Enzyme modulator
Q02750	BXGT012662	Dual specificity mitogen-activated protein kinase kinase 1	5604	reviewed	Kinase
Q03468	BXGT012716	DNA excision repair protein ERCC-6	2074	reviewed
Q04721	BXGT012777	Neurogenic locus notch homolog protein 2	4853	reviewed
Q04844	BXGT012789	Acetylcholine receptor subunit epsilon	1145	reviewed	Ion channel
Q06124	BXGT012856	Tyrosine-protein phosphatase non-receptor type 11	5781	reviewed
Q06210	BXGT012864	Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1	2673	reviewed	Enzyme
Q07889	BXGT012946	Son of sevenless homolog 1	6654	reviewed	Enzyme modulator
Q09472	BXGT013038	Histone acetyltransferase p300	2033	reviewed
Q12797	BXGT013266	Aspartyl/asparaginyl beta-hydroxylase	444	reviewed
Q12959	BXGT013283	Disks large homolog 1	1739	reviewed	Receptor
Q13535	BXGT013370	Serine/threonine-protein kinase ATR	545	reviewed	Kinase
Q13936	BXGT013404	Voltage-dependent L-type calcium channel subunit alpha-1C	775	reviewed	Ion channel
Q15223	BXGT013551	Nectin-1	5818	reviewed
Q8TC12	BXGT018793	Retinol dehydrogenase 11	51109	reviewed	Enzyme
Q92793	BXGT019374	CREB-binding protein	1387	reviewed
Q9BYT8	BXGT020190	Neurolysin, mitochondrial	57486	reviewed	Enzyme
Q9Y2R2	BXGT022243	Tyrosine-protein phosphatase non-receptor type 22	26191	reviewed
Q9Y646	BXGT022317	Carboxypeptidase Q	10404	reviewed	Enzyme
Q7Z624	BXGT022792	Calmodulin-lysine N-methyltransferase	79823	reviewed
Q59FF6	BXGT023693	Excision repair cross-complementing rodent repair deficiency, complementation group 6 variant	2074	unreviewed
P08123	BXGT024477	Collagen alpha-2(I) chain	1278	reviewed
P0DP25	BXGT024595	Calmodulin-3	808	reviewed
P35250	BXGT025854	Replication factor C subunit 2	5982	reviewed	Enzyme
P51798	BXGT026083	H(+)/Cl(-) exchange transporter 7	1186	reviewed	Ion channel

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}